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The map label for this gene is rocE [H]

Identifier: 89256541

GI number: 89256541

Start: 1171299

End: 1172666

Strand: Direct

Name: rocE [H]

Synonym: FTL_1220

Alternate gene names: 89256541

Gene position: 1171299-1172666 (Clockwise)

Preceding gene: 89256529

Following gene: 89256542

Centisome position: 61.78

GC content: 30.19

Gene sequence:

>1368_bases
ATGGATAATAATCAAGACAAATTAAAAAGAGATATTTTATCACGTCATATCGTTATGATTTCTTTAGGTGGGACTATTTC
AGCAAGTTTTTTCCTTGGCATAGGAAGTATTCTAAATACTGTTGGAGCATTTGGCACCGTAATAGGATTTTTTATTGGTG
GCATAATAATGATGTTAGTAATGATCAGCTTGGCTGAGATGGCTATTGAAATGCCTATAAGTGGTTCATTTCAAAGCTAT
GCAACCAAATTTATATCACCATATTCAGGATTCCTAACAGGTTGGTTATATTTATTAAATTGGTTGACTGCGGCAGCTGG
AGGACTTGTTGCAGCAGGGATTATTTGTAATAATTTCTACCCTGCTATTAGTGTTTGGCAATTCTGCTTAGCTATTATAC
TAATTGTCAGTTTGCTAAATTTATGTGCAGTTAGAGTATTTGCAGAAATAGAGTTTTGGCTATCAGCTATAAAAATTATA
ACTATCATAATTTTTATAATAATAGGAATTGGTATTATTGGTGGTTTTTTACATTCTAATAAGCCTATTGCAGGATTAGT
CAATTTTTATGTAGATGGACTTTTTCCAAATGGTTTTAAAGCTTTTTTATTTGGTTTAGTAATTATAGTCTGTACTTTCC
AAGGTGCTGAAGTAGTTGGTATAGCAGCTGGAGAAACTAAAGAACCTGAAAAAAATATTCGTAAAGCTATTAGAAGTGTG
GCTGTTAGAATACTTTTATTTTTTGTATTCTCATCCTTTATCATAGCTTATGTTATTCCATATAAAGATTCCGGAATTAC
TAACACTCCTTTTGTGACAGTATTACAATTAGTCAATATTAAATATGTTGATACGATTATGCAGCTAGTAATTCTCTCAG
CAAGTCTTTCTGCTGTTAATTCATGTTTTTATACTTGTGCAAGGCTAATGTGGTCGATGGCAGAAGCTAATCAAGCCCCA
AAAATTTTTGCTAAAATTAGTAAAAAACAGATCCCTATATATGGTGTAGTATTTGTAGCATTATTATCATGTATTTGCTT
AATCACAAAATTTATTGGAGCTGAAAAAATATTTATATTAGTAATATCATCATCTGGTATGGTTGGATGTATGATATGGA
TTATAATTAGTATGTGTCATATATATTTTAGAAAATCTCTTACAGCATCACAAATTGAAAGTTTACGTTTTAAAGCATGG
GGATTTCCTTTGATACCTTATACAAGCATTTTGTTTAACTCATGTGTCATATTAGCAATGTTTTGGGATCCTGAACAACG
TATGGTTGTATACTCAGGTGTAATATTAATTTTGTTATTTTCATTTCTCTATAAGTTTTATTATAAAAAAATAATAGTAA
AAACTTGA

Upstream 100 bases:

>100_bases
ATAATAATTTTACAAATTCAATTTAGTGATAAAACATTTCTTGACCAATATTGATTATGAAATACTCTATCCTTAGTAGT
AACTATCAACAAATATAAAA

Downstream 100 bases:

>100_bases
TAAACTATTAATTTAATAGTACTATTAAAAAATAGTATGGAACAATAAGATATGAAAGATTATCAAAGTTTAACAGAACA
AATCAATAATATTGAGAATA

Product: amino-acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MDNNQDKLKRDILSRHIVMISLGGTISASFFLGIGSILNTVGAFGTVIGFFIGGIIMMLVMISLAEMAIEMPISGSFQSY
ATKFISPYSGFLTGWLYLLNWLTAAAGGLVAAGIICNNFYPAISVWQFCLAIILIVSLLNLCAVRVFAEIEFWLSAIKII
TIIIFIIIGIGIIGGFLHSNKPIAGLVNFYVDGLFPNGFKAFLFGLVIIVCTFQGAEVVGIAAGETKEPEKNIRKAIRSV
AVRILLFFVFSSFIIAYVIPYKDSGITNTPFVTVLQLVNIKYVDTIMQLVILSASLSAVNSCFYTCARLMWSMAEANQAP
KIFAKISKKQIPIYGVVFVALLSCICLITKFIGAEKIFILVISSSGMVGCMIWIIISMCHIYFRKSLTASQIESLRFKAW
GFPLIPYTSILFNSCVILAMFWDPEQRMVVYSGVILILLFSFLYKFYYKKIIVKT

Sequences:

>Translated_455_residues
MDNNQDKLKRDILSRHIVMISLGGTISASFFLGIGSILNTVGAFGTVIGFFIGGIIMMLVMISLAEMAIEMPISGSFQSY
ATKFISPYSGFLTGWLYLLNWLTAAAGGLVAAGIICNNFYPAISVWQFCLAIILIVSLLNLCAVRVFAEIEFWLSAIKII
TIIIFIIIGIGIIGGFLHSNKPIAGLVNFYVDGLFPNGFKAFLFGLVIIVCTFQGAEVVGIAAGETKEPEKNIRKAIRSV
AVRILLFFVFSSFIIAYVIPYKDSGITNTPFVTVLQLVNIKYVDTIMQLVILSASLSAVNSCFYTCARLMWSMAEANQAP
KIFAKISKKQIPIYGVVFVALLSCICLITKFIGAEKIFILVISSSGMVGCMIWIIISMCHIYFRKSLTASQIESLRFKAW
GFPLIPYTSILFNSCVILAMFWDPEQRMVVYSGVILILLFSFLYKFYYKKIIVKT
>Mature_455_residues
MDNNQDKLKRDILSRHIVMISLGGTISASFFLGIGSILNTVGAFGTVIGFFIGGIIMMLVMISLAEMAIEMPISGSFQSY
ATKFISPYSGFLTGWLYLLNWLTAAAGGLVAAGIICNNFYPAISVWQFCLAIILIVSLLNLCAVRVFAEIEFWLSAIKII
TIIIFIIIGIGIIGGFLHSNKPIAGLVNFYVDGLFPNGFKAFLFGLVIIVCTFQGAEVVGIAAGETKEPEKNIRKAIRSV
AVRILLFFVFSSFIIAYVIPYKDSGITNTPFVTVLQLVNIKYVDTIMQLVILSASLSAVNSCFYTCARLMWSMAEANQAP
KIFAKISKKQIPIYGVVFVALLSCICLITKFIGAEKIFILVISSSGMVGCMIWIIISMCHIYFRKSLTASQIESLRFKAW
GFPLIPYTSILFNSCVILAMFWDPEQRMVVYSGVILILLFSFLYKFYYKKIIVKT

Specific function: Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine [H]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081708, Length=445, Percent_Identity=34.1573033707865, Blast_Score=295, Evalue=3e-81,
Organism=Escherichia coli, GI48994972, Length=453, Percent_Identity=34.878587196468, Blast_Score=271, Evalue=6e-74,
Organism=Escherichia coli, GI1788480, Length=459, Percent_Identity=33.5511982570806, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1786302, Length=434, Percent_Identity=32.0276497695853, Blast_Score=251, Evalue=8e-68,
Organism=Escherichia coli, GI1786602, Length=456, Percent_Identity=32.4561403508772, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1789017, Length=433, Percent_Identity=32.3325635103926, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1786789, Length=444, Percent_Identity=31.0810810810811, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1790653, Length=395, Percent_Identity=31.3924050632911, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI87081915, Length=416, Percent_Identity=29.5673076923077, Blast_Score=215, Evalue=4e-57,
Organism=Escherichia coli, GI87081869, Length=359, Percent_Identity=21.4484679665738, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082023, Length=335, Percent_Identity=23.5820895522388, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320772, Length=429, Percent_Identity=29.8368298368298, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6324061, Length=433, Percent_Identity=31.1778290993072, Blast_Score=203, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6324553, Length=472, Percent_Identity=29.4491525423729, Blast_Score=190, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6322892, Length=422, Percent_Identity=31.9905213270142, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6324059, Length=435, Percent_Identity=28.5057471264368, Blast_Score=176, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6324990, Length=491, Percent_Identity=27.0875763747454, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6324924, Length=483, Percent_Identity=26.7080745341615, Blast_Score=166, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6321053, Length=430, Percent_Identity=26.9767441860465, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6319543, Length=441, Percent_Identity=27.891156462585, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319824, Length=442, Percent_Identity=27.8280542986425, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6320717, Length=402, Percent_Identity=27.1144278606965, Blast_Score=152, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6320251, Length=440, Percent_Identity=25.6818181818182, Blast_Score=149, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6321629, Length=404, Percent_Identity=26.4851485148515, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6322967, Length=400, Percent_Identity=29.5, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6319542, Length=440, Percent_Identity=25.9090909090909, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6319608, Length=485, Percent_Identity=25.1546391752577, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6324981, Length=389, Percent_Identity=29.5629820051414, Blast_Score=119, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6320364, Length=488, Percent_Identity=23.3606557377049, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50355; Mature: 50355

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNNQDKLKRDILSRHIVMISLGGTISASFFLGIGSILNTVGAFGTVIGFFIGGIIMMLV
CCCCHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MISLAEMAIEMPISGSFQSYATKFISPYSGFLTGWLYLLNWLTAAAGGLVAAGIICNNFY
HHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PAISVWQFCLAIILIVSLLNLCAVRVFAEIEFWLSAIKIITIIIFIIIGIGIIGGFLHSN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KPIAGLVNFYVDGLFPNGFKAFLFGLVIIVCTFQGAEVVGIAAGETKEPEKNIRKAIRSV
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHH
AVRILLFFVFSSFIIAYVIPYKDSGITNTPFVTVLQLVNIKYVDTIMQLVILSASLSAVN
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SCFYTCARLMWSMAEANQAPKIFAKISKKQIPIYGVVFVALLSCICLITKFIGAEKIFIL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEE
VISSSGMVGCMIWIIISMCHIYFRKSLTASQIESLRFKAWGFPLIPYTSILFNSCVILAM
EEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEE
FWDPEQRMVVYSGVILILLFSFLYKFYYKKIIVKT
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7540694; 9384377 [H]