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The map label for this gene is pgk [H]

Identifier: 89256471

GI number: 89256471

Start: 1089209

End: 1090387

Strand: Direct

Name: pgk [H]

Synonym: FTL_1147

Alternate gene names: 89256471

Gene position: 1089209-1090387 (Clockwise)

Preceding gene: 89256470

Following gene: 89256472

Centisome position: 57.45

GC content: 36.56

Gene sequence:

>1179_bases
ATGAGTTTTCTAACATTGAAAGATGTTGATTTAAAAGATAAAAAAGTCTTGGTTCGTGTTGACTTCAACGTACCTGTTAA
AGATGGTAAGGTAACAAGTAAAGTTAGAATTGAAGCGGCTATTCCGACTATTCAATATATTCTAGATCAAGGTGGAGCTG
TGATTCTGATGTCACACCTTGGTCGTCCTACAGAGGGTGAGTATGATTCTCAGTTCTCTCTAGAGCCTGTTGCTAAAGCT
TTATCTGAAATTATCAATAAGCCGGTTAAGTTTGCTAAAGACTGGTTAGATGGTGTTGATGTTAAAGCTGGTGAAATTGT
CATGTGTGAAAATGTCCGCTTTAATATTGGTGAGAAAAAATCAACAGATGATTTATCTAAAAAGATTGCAAGCTTAGGTG
ATGTGTTTGTTATGGACGCTTTTGCTACAGCGCATAGAGCTCAAGCTTCGACCTACGGTGTTGCTAAGTATATTCCTGTA
GCATGTGCAGGGATATTGTTAACTAATGAAATTCAAGCATTAGAAAAAGCTTTAAAATCGCCGAAAAAACCAATGGCAGC
AATAGTTGGAGGGTCTAAGGTCTCTACTAAACTATCGGTGCTAAATAACCTTCTTGATAAGGTTGAAATTCTTATTGTTG
GTGGTGGTATTGCTAATACTTTCATAAAAGCAGAAGGTTTTGATGTTGGTAATTCATTGTATGAACAAGATCTTGTTGCT
GAAGCAACAGAGATTTTAGCTAAAGCTAAGGCTTTAGGGGTTAATATTCCTGTGCCAGTTGATGTAAGAGTTGCTAAAGA
GTTTAGCGAAAATGCCCAAGCAATCATTAAAAAGGTTTCCTATGTTGTTGCGGATGAGATGATTCTAGATATAGGTCCAG
AATCTCAAAAGATAATTGCTGAGCTGTTAAAATCAGCAAATACTATTTTATGGAATGGACCTGTTGGAGTATTTGAGTTT
GATAACTTTGCAGAGGGTACAAAAGCTTTATCTTTAGCTATAGCACAATCGCACGCTTTTTCAGTAGCTGGTGGTGGTGA
TACTATTGCTGCGATAGAAAAATTTGGCATTAAAGACCAAGTTTCTTATATATCAACAGCTGGTGGAGCATTCTTAGAGT
TTCTTGAAGGCAAGAAATTACCAGCTATAGAGATACTTAAAGAAAAAGCAATCAGGTAA

Upstream 100 bases:

>100_bases
TAAAGTAGTATCTTGGTATGACAATGAAATGTCTTATACAAATCAAATGGTTAGAGTAGTAGAGTACTTCGGAGCTCTAT
AAACATTATAGGTGATATAA

Downstream 100 bases:

>100_bases
TTTAGGATAATTTATATGAGAAGAACAAAAATTTTAGCTACTCTTGGTCCTGCTAGTGAATCAAGAGAAGCTCTAACAGA
GATGATTAAAGCAGGGGTTA

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGGAVILMSHLGRPTEGEYDSQFSLEPVAKA
LSEIINKPVKFAKDWLDGVDVKAGEIVMCENVRFNIGEKKSTDDLSKKIASLGDVFVMDAFATAHRAQASTYGVAKYIPV
ACAGILLTNEIQALEKALKSPKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGGIANTFIKAEGFDVGNSLYEQDLVA
EATEILAKAKALGVNIPVPVDVRVAKEFSENAQAIIKKVSYVVADEMILDIGPESQKIIAELLKSANTILWNGPVGVFEF
DNFAEGTKALSLAIAQSHAFSVAGGGDTIAAIEKFGIKDQVSYISTAGGAFLEFLEGKKLPAIEILKEKAIR

Sequences:

>Translated_392_residues
MSFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGGAVILMSHLGRPTEGEYDSQFSLEPVAKA
LSEIINKPVKFAKDWLDGVDVKAGEIVMCENVRFNIGEKKSTDDLSKKIASLGDVFVMDAFATAHRAQASTYGVAKYIPV
ACAGILLTNEIQALEKALKSPKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGGIANTFIKAEGFDVGNSLYEQDLVA
EATEILAKAKALGVNIPVPVDVRVAKEFSENAQAIIKKVSYVVADEMILDIGPESQKIIAELLKSANTILWNGPVGVFEF
DNFAEGTKALSLAIAQSHAFSVAGGGDTIAAIEKFGIKDQVSYISTAGGAFLEFLEGKKLPAIEILKEKAIR
>Mature_391_residues
SFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGGAVILMSHLGRPTEGEYDSQFSLEPVAKAL
SEIINKPVKFAKDWLDGVDVKAGEIVMCENVRFNIGEKKSTDDLSKKIASLGDVFVMDAFATAHRAQASTYGVAKYIPVA
CAGILLTNEIQALEKALKSPKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGGIANTFIKAEGFDVGNSLYEQDLVAE
ATEILAKAKALGVNIPVPVDVRVAKEFSENAQAIIKKVSYVVADEMILDIGPESQKIIAELLKSANTILWNGPVGVFEFD
NFAEGTKALSLAIAQSHAFSVAGGGDTIAAIEKFGIKDQVSYISTAGGAFLEFLEGKKLPAIEILKEKAIR

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=413, Percent_Identity=42.3728813559322, Blast_Score=308, Evalue=7e-84,
Organism=Homo sapiens, GI31543397, Length=411, Percent_Identity=42.5790754257908, Blast_Score=303, Evalue=1e-82,
Organism=Escherichia coli, GI1789294, Length=390, Percent_Identity=62.8205128205128, Blast_Score=483, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI17508823, Length=414, Percent_Identity=43.4782608695652, Blast_Score=321, Evalue=5e-88,
Organism=Saccharomyces cerevisiae, GI6319857, Length=414, Percent_Identity=43.2367149758454, Blast_Score=306, Evalue=3e-84,
Organism=Drosophila melanogaster, GI24581203, Length=413, Percent_Identity=38.9830508474576, Blast_Score=278, Evalue=6e-75,
Organism=Drosophila melanogaster, GI17136394, Length=416, Percent_Identity=39.6634615384615, Blast_Score=272, Evalue=3e-73,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 42011; Mature: 41880

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGGAVILMSHL
CCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCEEEEEECC
GRPTEGEYDSQFSLEPVAKALSEIINKPVKFAKDWLDGVDVKAGEIVMCENVRFNIGEKK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEECCCCCC
STDDLSKKIASLGDVFVMDAFATAHRAQASTYGVAKYIPVACAGILLTNEIQALEKALKS
CHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGGIANTFIKAEGFDVGNSLYEQDLVA
CCCCCEEEECCCHHHHHHHHHHHHHHHEEEEEECCCHHHHEEEECCCCCCHHHHHHHHHH
EATEILAKAKALGVNIPVPVDVRVAKEFSENAQAIIKKVSYVVADEMILDIGPESQKIIA
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHH
ELLKSANTILWNGPVGVFEFDNFAEGTKALSLAIAQSHAFSVAGGGDTIAAIEKFGIKDQ
HHHHCCCEEEECCCCCEEECCCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCCHHH
VSYISTAGGAFLEFLEGKKLPAIEILKEKAIR
HHHHHHCHHHHHHHHCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
SFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGGAVILMSHL
CEEEEECCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCEEEEEECC
GRPTEGEYDSQFSLEPVAKALSEIINKPVKFAKDWLDGVDVKAGEIVMCENVRFNIGEKK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEECCCCCC
STDDLSKKIASLGDVFVMDAFATAHRAQASTYGVAKYIPVACAGILLTNEIQALEKALKS
CHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGGIANTFIKAEGFDVGNSLYEQDLVA
CCCCCEEEECCCHHHHHHHHHHHHHHHEEEEEECCCHHHHEEEECCCCCCHHHHHHHHHH
EATEILAKAKALGVNIPVPVDVRVAKEFSENAQAIIKKVSYVVADEMILDIGPESQKIIA
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHH
ELLKSANTILWNGPVGVFEFDNFAEGTKALSLAIAQSHAFSVAGGGDTIAAIEKFGIKDQ
HHHHCCCEEEECCCCCEEECCCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCCHHH
VSYISTAGGAFLEFLEGKKLPAIEILKEKAIR
HHHHHHCHHHHHHHHCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA