Click here to switch to the map view.

The map label for this gene is oxyR [H]

Identifier: 89256353

GI number: 89256353

Start: 974513

End: 975382

Strand: Reverse

Name: oxyR [H]

Synonym: FTL_1014

Alternate gene names: 89256353

Gene position: 975382-974513 (Counterclockwise)

Preceding gene: 89256356

Following gene: 89256339

Centisome position: 51.44

GC content: 30.11

Gene sequence:

>870_bases
ATGAATACACGTACTCTTAAATATATCATTTCTGTGTATGAGACAAAAAGCTTTATTACAGCATCAGAAAAATGTTTTGT
CAGCCAACCTGCATTAAGTATGCAAATAAAGAAATTTGAAGAGTATATTGGTATCCAAATTTTTGAGCGCGGTACAAAAC
AAGTCTTGATAACTAAATCAGGAATGAAAATCGTCAACCAAGCTTATAAAATTCTTGATGAAGTAAATAATCTTAAGAAA
ATTGCTGAGCTACTCTTAGAGAATGGTAAAATCAGCATTACTATTGGCGCATTTCCAACTCTGTGTCCATACTTAATGCC
TAAAATTCTCCCTGCTATCAAACAAGAACTTCCGAATCTAAGTATTGCTGTAATTGAAGAAAAAACAGACATCCTTGTTA
AAATGCTTGATCAAGGTAAAATCGATTTTGCTTTACTAGCAACTCCTACTGAAAACTACCAATTCCATAGAAAAAAAGTT
TTTGATGATAAATTTTATGTAGCTGTAGCTAAAACTAATCCATTAGCAAAAAATAAACAAATATGTATAAGAGAAATAGT
TAAACAGAATCTTATGCTTCTTGATGAAGGTCATTGTCTTAGAGATCAAACTCTTAAACTCTGTGCGTTAAAAGAGTTTA
ATAATAACGACTTTAAAGGTAGTAGTCTAGAGACCCTAAGACAAATGGTATCTATCGATGAAGGTATAACTCTAGTACCT
AAAATTGCTTGCACTAAAGCCGATAATGTTAAATATATTGATATTGATAATAGAGATTTCTATAGAGAAATTGATTTAGT
TATGCGTAAAAGCTCAATATACGAAGATTTATTTGCTAAGATCGCTAAAATAATTTCAAATAATCATTAA

Upstream 100 bases:

>100_bases
CATGTCTAACTCCTTTGTTTTGTTAAGCTACGCTATTATTGTATTACTCTTGCACATAATTTAAAATATATAATATTTAT
AGTAACTATAAGATTTAGTT

Downstream 100 bases:

>100_bases
GCTCACATAAATATCATCCAAATACCCATAGCTATCATCATAATATTTTCTGTTAATGATAAAAATCCTAGAGGAACATT
ACTATTACCTCCTACACATG

Product: oxidative stress transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MNTRTLKYIISVYETKSFITASEKCFVSQPALSMQIKKFEEYIGIQIFERGTKQVLITKSGMKIVNQAYKILDEVNNLKK
IAELLLENGKISITIGAFPTLCPYLMPKILPAIKQELPNLSIAVIEEKTDILVKMLDQGKIDFALLATPTENYQFHRKKV
FDDKFYVAVAKTNPLAKNKQICIREIVKQNLMLLDEGHCLRDQTLKLCALKEFNNNDFKGSSLETLRQMVSIDEGITLVP
KIACTKADNVKYIDIDNRDFYREIDLVMRKSSIYEDLFAKIAKIISNNH

Sequences:

>Translated_289_residues
MNTRTLKYIISVYETKSFITASEKCFVSQPALSMQIKKFEEYIGIQIFERGTKQVLITKSGMKIVNQAYKILDEVNNLKK
IAELLLENGKISITIGAFPTLCPYLMPKILPAIKQELPNLSIAVIEEKTDILVKMLDQGKIDFALLATPTENYQFHRKKV
FDDKFYVAVAKTNPLAKNKQICIREIVKQNLMLLDEGHCLRDQTLKLCALKEFNNNDFKGSSLETLRQMVSIDEGITLVP
KIACTKADNVKYIDIDNRDFYREIDLVMRKSSIYEDLFAKIAKIISNNH
>Mature_289_residues
MNTRTLKYIISVYETKSFITASEKCFVSQPALSMQIKKFEEYIGIQIFERGTKQVLITKSGMKIVNQAYKILDEVNNLKK
IAELLLENGKISITIGAFPTLCPYLMPKILPAIKQELPNLSIAVIEEKTDILVKMLDQGKIDFALLATPTENYQFHRKKV
FDDKFYVAVAKTNPLAKNKQICIREIVKQNLMLLDEGHCLRDQTLKLCALKEFNNNDFKGSSLETLRQMVSIDEGITLVP
KIACTKADNVKYIDIDNRDFYREIDLVMRKSSIYEDLFAKIAKIISNNH

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=289, Percent_Identity=35.9861591695502, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI157672245, Length=273, Percent_Identity=23.4432234432234, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788887, Length=195, Percent_Identity=27.6923076923077, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787879, Length=274, Percent_Identity=23.7226277372263, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693105, Length=287, Percent_Identity=23.6933797909408, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787530, Length=273, Percent_Identity=21.978021978022, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788748, Length=241, Percent_Identity=21.1618257261411, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788296, Length=265, Percent_Identity=22.6415094339623, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI2367136, Length=236, Percent_Identity=22.4576271186441, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788481, Length=237, Percent_Identity=23.2067510548523, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=180, Percent_Identity=24.4444444444444, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87081904, Length=203, Percent_Identity=20.6896551724138, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33099; Mature: 33099

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRTLKYIISVYETKSFITASEKCFVSQPALSMQIKKFEEYIGIQIFERGTKQVLITKS
CCCHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCHHEEECCCCEEEEECC
GMKIVNQAYKILDEVNNLKKIAELLLENGKISITIGAFPTLCPYLMPKILPAIKQELPNL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCC
SIAVIEEKTDILVKMLDQGKIDFALLATPTENYQFHRKKVFDDKFYVAVAKTNPLAKNKQ
EEEEEECHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCCEEEEEEECCCCCCCCHH
ICIREIVKQNLMLLDEGHCLRDQTLKLCALKEFNNNDFKGSSLETLRQMVSIDEGITLVP
HHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEC
KIACTKADNVKYIDIDNRDFYREIDLVMRKSSIYEDLFAKIAKIISNNH
CEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTRTLKYIISVYETKSFITASEKCFVSQPALSMQIKKFEEYIGIQIFERGTKQVLITKS
CCCHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCHHEEECCCCEEEEECC
GMKIVNQAYKILDEVNNLKKIAELLLENGKISITIGAFPTLCPYLMPKILPAIKQELPNL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCC
SIAVIEEKTDILVKMLDQGKIDFALLATPTENYQFHRKKVFDDKFYVAVAKTNPLAKNKQ
EEEEEECHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCCEEEEEEECCCCCCCCHH
ICIREIVKQNLMLLDEGHCLRDQTLKLCALKEFNNNDFKGSSLETLRQMVSIDEGITLVP
HHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEC
KIACTKADNVKYIDIDNRDFYREIDLVMRKSSIYEDLFAKIAKIISNNH
CEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8890216 [H]