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The map label for this gene is tsaA [H]

Identifier: 89256340

GI number: 89256340

Start: 964207

End: 964806

Strand: Direct

Name: tsaA [H]

Synonym: FTL_0996

Alternate gene names: 89256340

Gene position: 964207-964806 (Clockwise)

Preceding gene: 89256335

Following gene: 89256341

Centisome position: 50.85

GC content: 37.0

Gene sequence:

>600_bases
ATGGTATTAGTAGGTAAAAAAGCACCACTATTCAATGCACCAGCTGTTTTAGGTAATGGTGAGATTGTTGATAGCTATGA
TTTTGCAAAAGCTATCCAAGGTAAGTATGCTATTGTTGTATTCTACCCATTAGATTTTACATTTGTATGTCCATCTGAGC
TTATTGCTTTAGATAAAAGAACAGCTAAGCTAAAAGAGCTTGGTGTAGAAGTTGTTTCTGTATCAATTGACTCACACTTT
ACTCATAATGCTTGGAGAAATACACCAATAAATGATGGTGGTATTGGACCAGTTAAATATACTATGGTTGCTGATATTAA
CCAAGAAATCGTTAAAGCATACGATGTCCAAGCTGCTGGTGGTATGGCTTTTAGAGGTACTTTCCTAATCGATAAGTCAG
GTGTAGTGCGTCATCAAGTGGTTAATGATCTACCATTAGGTAGAAATATGGATGAAGTTATCAGAATGGTAGAAGCTTTA
CAATTCCACGAAGAGCATGGAGAAGTTTGTCCAGCTGGGTGGAAAAAAGGTGACCAAGGTATGAAAGCTTCACCTCAAGG
TGTTGCAGAATATCTATCTGATCACGTTATCGATCTATAA

Upstream 100 bases:

>100_bases
AGCATATTATTTTCTGAAATCAATATTATTAGCGATATTATATACGATAAATAGAGTTGACATAAGTGTAATTAATAAGC
AAAATTACAAGCATGAAATT

Downstream 100 bases:

>100_bases
CAAAAATTATTTATATATAAATATTTCTAACCTGTAAAAATTCTGGGTGTTTTAAGCTGTATAGATGAGAAATGTTTTTA
TAACTCTATTGAGTTTGCTT

Product: AhpC/Tsa family protein

Products: NA

Alternate protein names: 26 kDa antigen; Thioredoxin reductase [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MVLVGKKAPLFNAPAVLGNGEIVDSYDFAKAIQGKYAIVVFYPLDFTFVCPSELIALDKRTAKLKELGVEVVSVSIDSHF
THNAWRNTPINDGGIGPVKYTMVADINQEIVKAYDVQAAGGMAFRGTFLIDKSGVVRHQVVNDLPLGRNMDEVIRMVEAL
QFHEEHGEVCPAGWKKGDQGMKASPQGVAEYLSDHVIDL

Sequences:

>Translated_199_residues
MVLVGKKAPLFNAPAVLGNGEIVDSYDFAKAIQGKYAIVVFYPLDFTFVCPSELIALDKRTAKLKELGVEVVSVSIDSHF
THNAWRNTPINDGGIGPVKYTMVADINQEIVKAYDVQAAGGMAFRGTFLIDKSGVVRHQVVNDLPLGRNMDEVIRMVEAL
QFHEEHGEVCPAGWKKGDQGMKASPQGVAEYLSDHVIDL
>Mature_199_residues
MVLVGKKAPLFNAPAVLGNGEIVDSYDFAKAIQGKYAIVVFYPLDFTFVCPSELIALDKRTAKLKELGVEVVSVSIDSHF
THNAWRNTPINDGGIGPVKYTMVADINQEIVKAYDVQAAGGMAFRGTFLIDKSGVVRHQVVNDLPLGRNMDEVIRMVEAL
QFHEEHGEVCPAGWKKGDQGMKASPQGVAEYLSDHVIDL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=194, Percent_Identity=47.9381443298969, Blast_Score=192, Evalue=1e-49,
Organism=Homo sapiens, GI4505591, Length=191, Percent_Identity=47.1204188481675, Blast_Score=191, Evalue=3e-49,
Organism=Homo sapiens, GI32455266, Length=191, Percent_Identity=47.1204188481675, Blast_Score=191, Evalue=3e-49,
Organism=Homo sapiens, GI32455264, Length=191, Percent_Identity=47.1204188481675, Blast_Score=191, Evalue=3e-49,
Organism=Homo sapiens, GI5802974, Length=191, Percent_Identity=45.5497382198953, Blast_Score=181, Evalue=3e-46,
Organism=Homo sapiens, GI32483377, Length=190, Percent_Identity=45.2631578947368, Blast_Score=181, Evalue=5e-46,
Organism=Homo sapiens, GI5453549, Length=191, Percent_Identity=42.9319371727749, Blast_Score=176, Evalue=9e-45,
Organism=Homo sapiens, GI33188454, Length=83, Percent_Identity=50.6024096385542, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1786822, Length=186, Percent_Identity=35.4838709677419, Blast_Score=124, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17554494, Length=187, Percent_Identity=44.3850267379679, Blast_Score=179, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI193204376, Length=194, Percent_Identity=44.8453608247423, Blast_Score=175, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI32565831, Length=194, Percent_Identity=44.8453608247423, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6323613, Length=190, Percent_Identity=40.5263157894737, Blast_Score=156, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6320661, Length=192, Percent_Identity=38.0208333333333, Blast_Score=146, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6319407, Length=184, Percent_Identity=24.4565217391304, Blast_Score=72, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24656348, Length=192, Percent_Identity=46.875, Blast_Score=188, Evalue=2e-48,
Organism=Drosophila melanogaster, GI17864676, Length=192, Percent_Identity=46.875, Blast_Score=188, Evalue=2e-48,
Organism=Drosophila melanogaster, GI17738015, Length=198, Percent_Identity=41.9191919191919, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI21357347, Length=199, Percent_Identity=41.7085427135678, Blast_Score=170, Evalue=6e-43,
Organism=Drosophila melanogaster, GI17157991, Length=193, Percent_Identity=42.4870466321244, Blast_Score=166, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24641739, Length=193, Percent_Identity=42.4870466321244, Blast_Score=166, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24581278, Length=185, Percent_Identity=27.027027027027, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21760; Mature: 21760

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLVGKKAPLFNAPAVLGNGEIVDSYDFAKAIQGKYAIVVFYPLDFTFVCPSELIALDKR
CEEECCCCCCCCCCEEECCCCEECCHHHHHHHCCCEEEEEEECCCEEEECCHHHHHHHHH
TAKLKELGVEVVSVSIDSHFTHNAWRNTPINDGGIGPVKYTMVADINQEIVKAYDVQAAG
HHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCC
GMAFRGTFLIDKSGVVRHQVVNDLPLGRNMDEVIRMVEALQFHEEHGEVCPAGWKKGDQG
CEEEEEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
MKASPQGVAEYLSDHVIDL
CCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVLVGKKAPLFNAPAVLGNGEIVDSYDFAKAIQGKYAIVVFYPLDFTFVCPSELIALDKR
CEEECCCCCCCCCCEEECCCCEECCHHHHHHHCCCEEEEEEECCCEEEECCHHHHHHHHH
TAKLKELGVEVVSVSIDSHFTHNAWRNTPINDGGIGPVKYTMVADINQEIVKAYDVQAAG
HHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCC
GMAFRGTFLIDKSGVVRHQVVNDLPLGRNMDEVIRMVEALQFHEEHGEVCPAGWKKGDQG
CEEEEEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
MKASPQGVAEYLSDHVIDL
CCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682; 1987145 [H]