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The map label for this gene is hsdM [C]

Identifier: 89256323

GI number: 89256323

Start: 945953

End: 948280

Strand: Direct

Name: hsdM [C]

Synonym: FTL_0976

Alternate gene names: 89256323

Gene position: 945953-948280 (Clockwise)

Preceding gene: 89256322

Following gene: 89256324

Centisome position: 49.89

GC content: 31.01

Gene sequence:

>2328_bases
ATGGATCAAGAAGTTAAGCTTACTAGCTCAAGCCGTGGTACAGGCAGAGCATTAGCTGATTTAATTGTTTGGAAAAGTGC
TGAAGACAAAAAGAAAAATAAAACTGCTTTTATGGTCTTAGAGTTTAAAGCTGAAAACCTAGAACTAAAAGTAGAAGACT
GTTATCAGGATTATAACTATGCAACTTGGTCAAGAGCAGATCTTTTTGCAGTATCTAATGGTAAAGAAACTCAAGTTTAT
AAAGTTGTAGATACCGAGCTACCTTTAAGTTTGAAGCCTCTTGGTGAAATACCAAATGCTAATATTATAAATAATGCAAA
GAAACTAAAAGAAGAGCTAGAAAAAACGGTAGAGTTTAAGGGCGATGAGTTTGCAAAGGTTCTAAATAAGTGTCATAACA
TTATTAGAAATAATGACAAGCTTTCACCAGAAGCAGCTTTTGATGAGATTAGTAAAGTTCTTTTTATCAAGATAATGTAT
GAAAGAAATATTAATCAAAACCAGATGTTTTCACTAGATGAATTTAAAAGGTTAAGAGAAAACTTTAGAGAAATTCACAA
GGGAACATCTCAAGAAAATGACTCTTTTATTCAGTATAGATTTGAGCAGGTAAAAAGAGAGTTTGAAAAAGATCATATTT
TCGAACCAAATGAAACTATCCGTATTAGAGAATCTAGTTTTGAAGACATTGTAAAAGAGCTAGAAAAATATAATTTAACA
AAAACTGGTGCGGATGTTAAAGGTATAGCTTTTGAGACCTTCTTAGGACGCACATTTAGGGGTGAGCTAGGACAATTTTT
CACACCACGAAAAGTCGTAGAATTTATGGTTGATGTTTTGGATATTAAGCAAAATGAGTTGATCTGTGATCCTTGTGCTG
GTAGTGGAGGCTTTTTAATACGAGCTTTTGAAATAGTCAAAGATAAAATAGATGAGAAATATATTAGGCTTAAAAAACTA
AAACAAAGAGAAGTATTTGGCGAGAATCTAGAAAATATTGATGATGAAAAGCTAAAAGCAAAGTATGAGCAAGTAATAAA
TGAACTTAATGAAAAGCAAAAACTAGAGATCCAATATCTTTCAAAATCATCTATATTTGGTACAGATGCAAACCCTAGAA
TGGCAAGAGTATCTAAAATGAATATGATAATGCATGGAGATGGGCATAATGGTATTCATCATAATGATGGTTTGCTAAAT
GTAAATGGTATTTTTAGAAATCGTTTTGATGTGATTTTGACAAATCCGCCATTTGGTACAAATCTTGGTAAAGATAATTC
TAAAGTCTCAGAAGAAGATAAATATACCGATGAAAAGATGATAACACACTATAAAAAAATCTATGGTGATGTTTATGAAG
AGGAGCTAAAACAGGTTACAGATAACTTTGGTAAACCAATCAGAAGTTTATACAAAACTGGTGAAATATCAGGAGCAACA
GAAGTTCTATTTGTTGAGAGATGTTTAGACTTACTAAAAGCTGGCGGTAGAATGGGTATAGTTTTGCCAGAAGGTGTACT
AAATAGTTCAAACTTACAAAAAGCTAGAGAATATTTTGAAAGTAGAGCAAAAATATTGCTAATAGTTTCATTACCTCAAG
ATTTATTTGTAAGCTCAGGAGCAACTGTAAAGACTAGTTTAGTTTTTTTGAAAAAGTTTACAGTAGAAGAGCAAAAGCAA
GATAAAAAAGGTCTACTTAGGTTTGTGAGGTTTGAGCAATTACAACGCTGGGATACTGATTTTTTTAAGCAAAAAGAAGG
TTATTCATCAAAATATGAAACTGTTTCTTATGAAGATTTATTTGTTAGCTTAAATAATGGTATTGCTGCAAGAAATTATG
CAAGTGATGGTATAAGATACTTGAAAGTTTCTGACATAAAGGATAATTACATAAATAATAAGCCTTTTTATGTGAATAAG
TATAAAGAATCAGATTTGATTGAAAAAGGAACATTGTTAATAACGAGGAAAGGAACAGTTGGAAACTCTTATTATCTTGA
TAAGGATGGTTCATTTGTTGCATCTTCAGAAATATTTATCATAAAGTTGAATGATAAAGTTAATGGTAATTACTTGTCTG
AAATAAATTTATCTAGTTTTGTGAAAAAACAGTATCGAGAAAAGTCAACAGGGACTATAATGCCAAGTCTTTCACAACCA
AAATTAAAAAGCATCTTAATACCTCTACCACCACTAGAAATCCAAAACCATATAGCTGTGCGTATTCAAAAGCTAAAAGA
TTATATAAAAGCACTAGAACAACAAGCAGAGCAAAATAGAGAAAATGCTCTAAGGAATTTTGAAGCCGAGATTTTTAGTA
AAGAATGA

Upstream 100 bases:

>100_bases
CCCATTAAAAAATAAATGGTTAGAAGCAAAGCCTGAAGAAAAAGTAAGACAACGATTTATTTGTGATTTAGTTAATGACT
ACAGTTATTCTTTAGAGCAA

Downstream 100 bases:

>100_bases
TTCTCCTCTTGAGAGGAGTACCTTGCGAAGCAAGGGGAGGTGTGGTTGACAGAAGTTGAGTTAATCCGCTAGGTATACTT
TTAGAACACACCCCGCCAAC

Product: hypothetical protein

Products: S-Adenosyl-L-Homocysteine; DNA 6-Methylaminopurine. [C]

Alternate protein names: Type I Restriction- System M Subunit; Type I Restriction- System Methyltransferase Subunit; DNA Methylase-Type I Restriction- System; Type I Site-Specific Deoxyribonuclease; Type I Restriction EcoEI M Protein; N-6 DNA Methylase Family; Restriction- Protein; Restriction Endonuclease N6_Mtase Domain Protein; Type I Restriction System N-6 DNA Methylase; Type I Restriction- System Methylation Subunit; Type I Restriction/ System N-6 DNA Methyltransferase; NAD-Dependent DNA Ligase LigA; Type I Restriction- System; SsmT Protein; Restriction System Methylase; Type I Restriction- System M-Subunit-Like Protein; XmnI Methyltransferase

Number of amino acids: Translated: 775; Mature: 775

Protein sequence:

>775_residues
MDQEVKLTSSSRGTGRALADLIVWKSAEDKKKNKTAFMVLEFKAENLELKVEDCYQDYNYATWSRADLFAVSNGKETQVY
KVVDTELPLSLKPLGEIPNANIINNAKKLKEELEKTVEFKGDEFAKVLNKCHNIIRNNDKLSPEAAFDEISKVLFIKIMY
ERNINQNQMFSLDEFKRLRENFREIHKGTSQENDSFIQYRFEQVKREFEKDHIFEPNETIRIRESSFEDIVKELEKYNLT
KTGADVKGIAFETFLGRTFRGELGQFFTPRKVVEFMVDVLDIKQNELICDPCAGSGGFLIRAFEIVKDKIDEKYIRLKKL
KQREVFGENLENIDDEKLKAKYEQVINELNEKQKLEIQYLSKSSIFGTDANPRMARVSKMNMIMHGDGHNGIHHNDGLLN
VNGIFRNRFDVILTNPPFGTNLGKDNSKVSEEDKYTDEKMITHYKKIYGDVYEEELKQVTDNFGKPIRSLYKTGEISGAT
EVLFVERCLDLLKAGGRMGIVLPEGVLNSSNLQKAREYFESRAKILLIVSLPQDLFVSSGATVKTSLVFLKKFTVEEQKQ
DKKGLLRFVRFEQLQRWDTDFFKQKEGYSSKYETVSYEDLFVSLNNGIAARNYASDGIRYLKVSDIKDNYINNKPFYVNK
YKESDLIEKGTLLITRKGTVGNSYYLDKDGSFVASSEIFIIKLNDKVNGNYLSEINLSSFVKKQYREKSTGTIMPSLSQP
KLKSILIPLPPLEIQNHIAVRIQKLKDYIKALEQQAEQNRENALRNFEAEIFSKE

Sequences:

>Translated_775_residues
MDQEVKLTSSSRGTGRALADLIVWKSAEDKKKNKTAFMVLEFKAENLELKVEDCYQDYNYATWSRADLFAVSNGKETQVY
KVVDTELPLSLKPLGEIPNANIINNAKKLKEELEKTVEFKGDEFAKVLNKCHNIIRNNDKLSPEAAFDEISKVLFIKIMY
ERNINQNQMFSLDEFKRLRENFREIHKGTSQENDSFIQYRFEQVKREFEKDHIFEPNETIRIRESSFEDIVKELEKYNLT
KTGADVKGIAFETFLGRTFRGELGQFFTPRKVVEFMVDVLDIKQNELICDPCAGSGGFLIRAFEIVKDKIDEKYIRLKKL
KQREVFGENLENIDDEKLKAKYEQVINELNEKQKLEIQYLSKSSIFGTDANPRMARVSKMNMIMHGDGHNGIHHNDGLLN
VNGIFRNRFDVILTNPPFGTNLGKDNSKVSEEDKYTDEKMITHYKKIYGDVYEEELKQVTDNFGKPIRSLYKTGEISGAT
EVLFVERCLDLLKAGGRMGIVLPEGVLNSSNLQKAREYFESRAKILLIVSLPQDLFVSSGATVKTSLVFLKKFTVEEQKQ
DKKGLLRFVRFEQLQRWDTDFFKQKEGYSSKYETVSYEDLFVSLNNGIAARNYASDGIRYLKVSDIKDNYINNKPFYVNK
YKESDLIEKGTLLITRKGTVGNSYYLDKDGSFVASSEIFIIKLNDKVNGNYLSEINLSSFVKKQYREKSTGTIMPSLSQP
KLKSILIPLPPLEIQNHIAVRIQKLKDYIKALEQQAEQNRENALRNFEAEIFSKE
>Mature_775_residues
MDQEVKLTSSSRGTGRALADLIVWKSAEDKKKNKTAFMVLEFKAENLELKVEDCYQDYNYATWSRADLFAVSNGKETQVY
KVVDTELPLSLKPLGEIPNANIINNAKKLKEELEKTVEFKGDEFAKVLNKCHNIIRNNDKLSPEAAFDEISKVLFIKIMY
ERNINQNQMFSLDEFKRLRENFREIHKGTSQENDSFIQYRFEQVKREFEKDHIFEPNETIRIRESSFEDIVKELEKYNLT
KTGADVKGIAFETFLGRTFRGELGQFFTPRKVVEFMVDVLDIKQNELICDPCAGSGGFLIRAFEIVKDKIDEKYIRLKKL
KQREVFGENLENIDDEKLKAKYEQVINELNEKQKLEIQYLSKSSIFGTDANPRMARVSKMNMIMHGDGHNGIHHNDGLLN
VNGIFRNRFDVILTNPPFGTNLGKDNSKVSEEDKYTDEKMITHYKKIYGDVYEEELKQVTDNFGKPIRSLYKTGEISGAT
EVLFVERCLDLLKAGGRMGIVLPEGVLNSSNLQKAREYFESRAKILLIVSLPQDLFVSSGATVKTSLVFLKKFTVEEQKQ
DKKGLLRFVRFEQLQRWDTDFFKQKEGYSSKYETVSYEDLFVSLNNGIAARNYASDGIRYLKVSDIKDNYINNKPFYVNK
YKESDLIEKGTLLITRKGTVGNSYYLDKDGSFVASSEIFIIKLNDKVNGNYLSEINLSSFVKKQYREKSTGTIMPSLSQP
KLKSILIPLPPLEIQNHIAVRIQKLKDYIKALEQQAEQNRENALRNFEAEIFSKE

Specific function: The M And S Subunits Together Form A Methyltransferase (Mtase) That Methylates Two Adenine Residues In Complementary Strands Of A Bipartite DNA Recognition Sequence. In The Presence Of The R Subunit The Complex Can Also Act As An Endonuclease, Binding To

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.72 [C]

Molecular weight: Translated: 89504; Mature: 89504

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQEVKLTSSSRGTGRALADLIVWKSAEDKKKNKTAFMVLEFKAENLELKVEDCYQDYNY
CCCCEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCEEEHHHHHCCCCC
ATWSRADLFAVSNGKETQVYKVVDTELPLSLKPLGEIPNANIINNAKKLKEELEKTVEFK
CCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
GDEFAKVLNKCHNIIRNNDKLSPEAAFDEISKVLFIKIMYERNINQNQMFSLDEFKRLRE
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEHHHCCCCCCCCCCHHHHHHHHH
NFREIHKGTSQENDSFIQYRFEQVKREFEKDHIFEPNETIRIRESSFEDIVKELEKYNLT
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCC
KTGADVKGIAFETFLGRTFRGELGQFFTPRKVVEFMVDVLDIKQNELICDPCAGSGGFLI
CCCCCCCCCHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHH
RAFEIVKDKIDEKYIRLKKLKQREVFGENLENIDDEKLKAKYEQVINELNEKQKLEIQYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHEEEEEEE
SKSSIFGTDANPRMARVSKMNMIMHGDGHNGIHHNDGLLNVNGIFRNRFDVILTNPPFGT
CCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCCCCCCEEEECCEECCCEEEEEECCCCCC
NLGKDNSKVSEEDKYTDEKMITHYKKIYGDVYEEELKQVTDNFGKPIRSLYKTGEISGAT
CCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCH
EVLFVERCLDLLKAGGRMGIVLPEGVLNSSNLQKAREYFESRAKILLIVSLPQDLFVSSG
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCHHHHHCCC
ATVKTSLVFLKKFTVEEQKQDKKGLLRFVRFEQLQRWDTDFFKQKEGYSSKYETVSYEDL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCEEEHHHE
FVSLNNGIAARNYASDGIRYLKVSDIKDNYINNKPFYVNKYKESDLIEKGTLLITRKGTV
EEEECCCEEECCCCCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCEEEEECCCC
GNSYYLDKDGSFVASSEIFIIKLNDKVNGNYLSEINLSSFVKKQYREKSTGTIMPSLSQP
CCCEEECCCCCEEEECCEEEEEECCCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCC
KLKSILIPLPPLEIQNHIAVRIQKLKDYIKALEQQAEQNRENALRNFEAEIFSKE
CHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDQEVKLTSSSRGTGRALADLIVWKSAEDKKKNKTAFMVLEFKAENLELKVEDCYQDYNY
CCCCEEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCEEEHHHHHCCCCC
ATWSRADLFAVSNGKETQVYKVVDTELPLSLKPLGEIPNANIINNAKKLKEELEKTVEFK
CCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
GDEFAKVLNKCHNIIRNNDKLSPEAAFDEISKVLFIKIMYERNINQNQMFSLDEFKRLRE
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEHHHCCCCCCCCCCHHHHHHHHH
NFREIHKGTSQENDSFIQYRFEQVKREFEKDHIFEPNETIRIRESSFEDIVKELEKYNLT
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCC
KTGADVKGIAFETFLGRTFRGELGQFFTPRKVVEFMVDVLDIKQNELICDPCAGSGGFLI
CCCCCCCCCHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHH
RAFEIVKDKIDEKYIRLKKLKQREVFGENLENIDDEKLKAKYEQVINELNEKQKLEIQYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHEEEEEEE
SKSSIFGTDANPRMARVSKMNMIMHGDGHNGIHHNDGLLNVNGIFRNRFDVILTNPPFGT
CCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCCCCCCEEEECCEECCCEEEEEECCCCCC
NLGKDNSKVSEEDKYTDEKMITHYKKIYGDVYEEELKQVTDNFGKPIRSLYKTGEISGAT
CCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCH
EVLFVERCLDLLKAGGRMGIVLPEGVLNSSNLQKAREYFESRAKILLIVSLPQDLFVSSG
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCHHHHHCCC
ATVKTSLVFLKKFTVEEQKQDKKGLLRFVRFEQLQRWDTDFFKQKEGYSSKYETVSYEDL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCEEEHHHE
FVSLNNGIAARNYASDGIRYLKVSDIKDNYINNKPFYVNKYKESDLIEKGTLLITRKGTV
EEEECCCEEECCCCCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCEEEEECCCC
GNSYYLDKDGSFVASSEIFIIKLNDKVNGNYLSEINLSSFVKKQYREKSTGTIMPSLSQP
CCCEEECCCCCEEEECCEEEEEECCCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCC
KLKSILIPLPPLEIQNHIAVRIQKLKDYIKALEQQAEQNRENALRNFEAEIFSKE
CHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; DNA Adenine; DNA [C]

Specific reaction: S-Adenosyl-L-Methionine + DNA Adenine = S-Adenosyl-L-Homocysteine + DNA 6-Methylaminopurine. Protein + DNA = Protein-DNA [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA