| Definition | Francisella tularensis subsp. holarctica LVS chromosome, complete genome. |
|---|---|
| Accession | NC_007880 |
| Length | 1,895,994 |
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The map label for this gene is cphA [H]
Identifier: 89256191
GI number: 89256191
Start: 812028
End: 814850
Strand: Direct
Name: cphA [H]
Synonym: FTL_0831
Alternate gene names: 89256191
Gene position: 812028-814850 (Clockwise)
Preceding gene: 89256189
Following gene: 89256192
Centisome position: 42.83
GC content: 36.1
Gene sequence:
>2823_bases ATGAAAATACTATCTACTAATGTTTATGTGGGACCTAACATTTATGCTAACTTTCCTGTTATAAGACATGAGATTGATCT AGGAGTGCTAGAAAATTGGCCTTCTGCAAAGATTGGAGACAAGTTTATAGATCAACTGGTGGAGAGCTTACCAGGATTAC AAGAGCATGGCTGTTCTTATAGAGAAAAAGGAGGATTCATCCGTAGATTAAGAGAGGATGAAGGTACTTGGATGGGACAT ATTTGGGAGCATGTGATTTTAGAGCTTCAAAGTATGGCTGGTAGTGATGTAACATTTGGACGTACTAGATCAACCGGTGA AGTAGGTCATTATAATATGGTTTATGAGTATAAGCAAAAGGATGTTGGTCTAAGAGCTATGGAATTAGCTAGAGACTTAT TGATATCTATATTGCCAGAGAACCTAAAAAAACAAGTAGAATTTGCAAATGAATATTTTGACTTTGAGTATGAAAAGGTT AAATTTATAAAATTTGCTCAAAGTAAAGAATTTGGACCTAGTACAGCTTCATTGGTAGAAGCCGCAAAGAAAAGAGATAT TCCATATATCCGTCTAAACGATCAATCTTTAGTACAGTTTGGTTATGGTAAGTATCAACAAAGAATTAGAGCAACGATTA CTGGTAAAACAACTAGTATTGCTGTTGATCTATCATGTGATAAAGAGCAGACAAACACGATATTGAGTAGTTTAGGCTTA CCTGTACCAAAGCAAAGAATGGTTACAACAGAAGAAGGCGCTGTAAGATCAGCTAAAATTTTAGGTTTTCCTTTAGTTGT TAAACCATTAGACGGTAACCATGGTAGAGGTATTTCAATTAATCTTAAGACAATTGAAGAAATAAAAGAAGCATTTGTTG AGGCTAATAAAGTTTCGCGTTATGTATTATTAGAACAATATGTAATAGGCTTTGACCATAGGATGCTTGTCGTTGATGGT AAGCTTATAGCTGTTGCAAAGAGAGTGCCTGGTCATGTAGTTGGTGATGGTAAGCATACAATTGCAGAACTAGTTGAGAT AGTTAACCAAGATCCACGTAGAGGTATCGGTCATGAGAAAGTTCTAACAAAGTTAGAGTTAGATTATCAGGCAAGAACAT TGCTAAGAGCAGCTGGTTATGATGAGAATACTATTCTTAAAGATGGCGAAGTATTTTACCTAAGATCTACAGCTAATTTA TCAACTGGTGGTACAGCTATAGATGTGACAGATATTGTTCATCCAGATAACAGAGATATGGCAGAGAGAGCTATTAAGGC AATTGGCTTAGATGTTGGTGGTGTGGATTTCCTTATTGATGATATTTCACAATCATATCATGATATCGGTGGAGCAATTT GTGAATGTAATGCCGCGCCAGGATTTAGAATGCATGTGGCACCAAGTGAAGGTAAGCCAAGAGACGTTGCTGGTGCAGTT ATTGATATGCTTATTCCTAGAGAGTACGGTAATGCTAGAATTCCTATTGCTGCAATCACAGGTACTAATGGTAAAACTAC AACTTCACGTATGGTAGCACATATGTGGAAAAATGCTGGTAAAGTTGTTGGATTAACAACTACTGATGGTGTATACATAA ATGGTAAACTTACAGTAGCGGGAGATACCACAGGACCAGCTTCAGCGCAAATGGTTTTGAAAGATCCATCTGTAGAAATG GCTATTTTGGAAACAGCAAGAGGCGGACTATTAAGAAGTGGTCTAGGTTATGACTATTGTAATGTTGGAGCTTGCTTAAA CATTTCTGCTGATCATTTAGGCTTGAAAGGTATTAACACTCTAGAAGACTTAGCTAAAGTGAAAAGTATAGTTGTTGAAG CTGCAAAAGATGTTGCAGTTTTAAATGCAGATGACCCTAATGTCTTGAAAATGTCAGCTAAAGTTACAGCTAAACATATT TTCTATGTGACAATGAACCCAGAGCATGCGTTAGTTAAACAGCATATACGTGCAGGTGGTAAGGCATGTATTATCGAGAA GGGTGTAAATGGAGATATGATTACAATCTTTGATAATCATATCCATATACCAGTATTATGGACACACTTAATACCAGCAA CTATGGAAGGTAAAGCTATTCATAATGTTCAAAACTCAATGTTTGCAATAGCTATATGCTATAGTATGGGAATGAGCTTA GATGATATGCGAGATGGTTTAAGAACTTTCGTAACATCATTCTATCAAGCCCCAGGACGTATGAATTGGTTTGAAGAACA TCCATTTAAAGTACTAATGGATTATGGACACAATCCAGCTGCTATCAAACTAGTTAGTCAAATGATTATGAATATGGAAT TCGCTGGCAAAAAAATATGCGTACTAGCTTCTCCTGGAGATAGAAGAGATGAGGATATTGCCGAGTTAGCAAAAACTGCG ACACCTTATTATGACTACTTTATTTGTAAGCGTGATGATGATACTAGAGGTAGAGCACCAGATGAAGTGCCAAGAATATT AAAAGAAGCATTAATTGAAGCAGGTATATCTGCTGATAATATTGAAATTATAGAAAGTGAAAAAGAAGCGGTGGATGCAG CACTGAATATGGCAGAAGAAGGCGACTTAGTAGTAATATTTGCTGATAAGCTAAAAAGAACTTGGAAGCAGATTATATAC TTTAACAAGGATCAAGAGTTTGATGGTAAAGATAAAAAACTTGAGAAACAAGAAATGTTTTCGGCTTCTGTAATAGCTCA AACCCCTAGCTTATCAGAAGAAATATCACAAGTTATAAAAGCTGGGATAATTTCTGATGATAGTGGTGTTAGAGTGGTGT ATCATGAAGAAGATAATGATTAA
Upstream 100 bases:
>100_bases CTTTATCAAAATCCGCTACTCTTGATTATATTTTTTATATATTATGTTTTATGAAGTATATATTATGTGTATACAAGATT GAATATCTAAGGAGCCTTGA
Downstream 100 bases:
>100_bases ATAGTCTTTTTAGAAGGAGACTTGTATGATTCCTGAAGGTTATTCACGTAGGCTAGTTGGCCCTAATTTGTTCTTTAAAG AAACTGGGACAGTGTTAGAT
Product: cyanophycin synthetase
Products: NA
Alternate protein names: Cyanophycin synthase [H]
Number of amino acids: Translated: 940; Mature: 940
Protein sequence:
>940_residues MKILSTNVYVGPNIYANFPVIRHEIDLGVLENWPSAKIGDKFIDQLVESLPGLQEHGCSYREKGGFIRRLREDEGTWMGH IWEHVILELQSMAGSDVTFGRTRSTGEVGHYNMVYEYKQKDVGLRAMELARDLLISILPENLKKQVEFANEYFDFEYEKV KFIKFAQSKEFGPSTASLVEAAKKRDIPYIRLNDQSLVQFGYGKYQQRIRATITGKTTSIAVDLSCDKEQTNTILSSLGL PVPKQRMVTTEEGAVRSAKILGFPLVVKPLDGNHGRGISINLKTIEEIKEAFVEANKVSRYVLLEQYVIGFDHRMLVVDG KLIAVAKRVPGHVVGDGKHTIAELVEIVNQDPRRGIGHEKVLTKLELDYQARTLLRAAGYDENTILKDGEVFYLRSTANL STGGTAIDVTDIVHPDNRDMAERAIKAIGLDVGGVDFLIDDISQSYHDIGGAICECNAAPGFRMHVAPSEGKPRDVAGAV IDMLIPREYGNARIPIAAITGTNGKTTTSRMVAHMWKNAGKVVGLTTTDGVYINGKLTVAGDTTGPASAQMVLKDPSVEM AILETARGGLLRSGLGYDYCNVGACLNISADHLGLKGINTLEDLAKVKSIVVEAAKDVAVLNADDPNVLKMSAKVTAKHI FYVTMNPEHALVKQHIRAGGKACIIEKGVNGDMITIFDNHIHIPVLWTHLIPATMEGKAIHNVQNSMFAIAICYSMGMSL DDMRDGLRTFVTSFYQAPGRMNWFEEHPFKVLMDYGHNPAAIKLVSQMIMNMEFAGKKICVLASPGDRRDEDIAELAKTA TPYYDYFICKRDDDTRGRAPDEVPRILKEALIEAGISADNIEIIESEKEAVDAALNMAEEGDLVVIFADKLKRTWKQIIY FNKDQEFDGKDKKLEKQEMFSASVIAQTPSLSEEISQVIKAGIISDDSGVRVVYHEEDND
Sequences:
>Translated_940_residues MKILSTNVYVGPNIYANFPVIRHEIDLGVLENWPSAKIGDKFIDQLVESLPGLQEHGCSYREKGGFIRRLREDEGTWMGH IWEHVILELQSMAGSDVTFGRTRSTGEVGHYNMVYEYKQKDVGLRAMELARDLLISILPENLKKQVEFANEYFDFEYEKV KFIKFAQSKEFGPSTASLVEAAKKRDIPYIRLNDQSLVQFGYGKYQQRIRATITGKTTSIAVDLSCDKEQTNTILSSLGL PVPKQRMVTTEEGAVRSAKILGFPLVVKPLDGNHGRGISINLKTIEEIKEAFVEANKVSRYVLLEQYVIGFDHRMLVVDG KLIAVAKRVPGHVVGDGKHTIAELVEIVNQDPRRGIGHEKVLTKLELDYQARTLLRAAGYDENTILKDGEVFYLRSTANL STGGTAIDVTDIVHPDNRDMAERAIKAIGLDVGGVDFLIDDISQSYHDIGGAICECNAAPGFRMHVAPSEGKPRDVAGAV IDMLIPREYGNARIPIAAITGTNGKTTTSRMVAHMWKNAGKVVGLTTTDGVYINGKLTVAGDTTGPASAQMVLKDPSVEM AILETARGGLLRSGLGYDYCNVGACLNISADHLGLKGINTLEDLAKVKSIVVEAAKDVAVLNADDPNVLKMSAKVTAKHI FYVTMNPEHALVKQHIRAGGKACIIEKGVNGDMITIFDNHIHIPVLWTHLIPATMEGKAIHNVQNSMFAIAICYSMGMSL DDMRDGLRTFVTSFYQAPGRMNWFEEHPFKVLMDYGHNPAAIKLVSQMIMNMEFAGKKICVLASPGDRRDEDIAELAKTA TPYYDYFICKRDDDTRGRAPDEVPRILKEALIEAGISADNIEIIESEKEAVDAALNMAEEGDLVVIFADKLKRTWKQIIY FNKDQEFDGKDKKLEKQEMFSASVIAQTPSLSEEISQVIKAGIISDDSGVRVVYHEEDND >Mature_940_residues MKILSTNVYVGPNIYANFPVIRHEIDLGVLENWPSAKIGDKFIDQLVESLPGLQEHGCSYREKGGFIRRLREDEGTWMGH IWEHVILELQSMAGSDVTFGRTRSTGEVGHYNMVYEYKQKDVGLRAMELARDLLISILPENLKKQVEFANEYFDFEYEKV KFIKFAQSKEFGPSTASLVEAAKKRDIPYIRLNDQSLVQFGYGKYQQRIRATITGKTTSIAVDLSCDKEQTNTILSSLGL PVPKQRMVTTEEGAVRSAKILGFPLVVKPLDGNHGRGISINLKTIEEIKEAFVEANKVSRYVLLEQYVIGFDHRMLVVDG KLIAVAKRVPGHVVGDGKHTIAELVEIVNQDPRRGIGHEKVLTKLELDYQARTLLRAAGYDENTILKDGEVFYLRSTANL STGGTAIDVTDIVHPDNRDMAERAIKAIGLDVGGVDFLIDDISQSYHDIGGAICECNAAPGFRMHVAPSEGKPRDVAGAV IDMLIPREYGNARIPIAAITGTNGKTTTSRMVAHMWKNAGKVVGLTTTDGVYINGKLTVAGDTTGPASAQMVLKDPSVEM AILETARGGLLRSGLGYDYCNVGACLNISADHLGLKGINTLEDLAKVKSIVVEAAKDVAVLNADDPNVLKMSAKVTAKHI FYVTMNPEHALVKQHIRAGGKACIIEKGVNGDMITIFDNHIHIPVLWTHLIPATMEGKAIHNVQNSMFAIAICYSMGMSL DDMRDGLRTFVTSFYQAPGRMNWFEEHPFKVLMDYGHNPAAIKLVSQMIMNMEFAGKKICVLASPGDRRDEDIAELAKTA TPYYDYFICKRDDDTRGRAPDEVPRILKEALIEAGISADNIEIIESEKEAVDAALNMAEEGDLVVIFADKLKRTWKQIIY FNKDQEFDGKDKKLEKQEMFSASVIAQTPSLSEEISQVIKAGIISDDSGVRVVYHEEDND
Specific function: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) [H]
COG id: COG1181
COG function: function code M; D-alanine-D-alanine ligase and related ATP-grasp enzymes
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ATP-grasp domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011761 - InterPro: IPR013651 - InterPro: IPR013815 - InterPro: IPR013816 - InterPro: IPR011810 - InterPro: IPR004101 - InterPro: IPR013221 [H]
Pfam domain/function: PF02875 Mur_ligase_C; PF08245 Mur_ligase_M; PF08443 RimK [H]
EC number: =6.3.2.29; =6.3.2.30 [H]
Molecular weight: Translated: 103994; Mature: 103994
Theoretical pI: Translated: 5.95; Mature: 5.95
Prosite motif: PS50975 ATP_GRASP
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKILSTNVYVGPNIYANFPVIRHEIDLGVLENWPSAKIGDKFIDQLVESLPGLQEHGCSY CEEEEEEEEECCCCEECCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCHHHHCCCC REKGGFIRRLREDEGTWMGHIWEHVILELQSMAGSDVTFGRTRSTGEVGHYNMVYEYKQK HHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCC DVGLRAMELARDLLISILPENLKKQVEFANEYFDFEYEKVKFIKFAQSKEFGPSTASLVE CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCCHHHHHH AAKKRDIPYIRLNDQSLVQFGYGKYQQRIRATITGKTTSIAVDLSCDKEQTNTILSSLGL HHHHCCCCEEEECCCHHHHHCHHHHHHHEEEEEECCEEEEEEEEECCCHHHHHHHHHCCC PVPKQRMVTTEEGAVRSAKILGFPLVVKPLDGNHGRGISINLKTIEEIKEAFVEANKVSR CCCHHHEEECCCCCCCEEEEECCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH YVLLEQYVIGFDHRMLVVDGKLIAVAKRVPGHVVGDGKHTIAELVEIVNQDPRRGIGHEK HHHHHHHHHCCCCEEEEECCCEEEEEHHCCCCEECCCHHHHHHHHHHHCCCCCCCCCHHH VLTKLELDYQARTLLRAAGYDENTILKDGEVFYLRSTANLSTGGTAIDVTDIVHPDNRDM HHHHHCCCHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCCCEEEEEECCCCCCHHH AERAIKAIGLDVGGVDFLIDDISQSYHDIGGAICECNAAPGFRMHVAPSEGKPRDVAGAV HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCCHHHHHH IDMLIPREYGNARIPIAAITGTNGKTTTSRMVAHMWKNAGKVVGLTTTDGVYINGKLTVA HHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEEE GDTTGPASAQMVLKDPSVEMAILETARGGLLRSGLGYDYCNVGACLNISADHLGLKGINT CCCCCCCCCEEEEECCCCEEEEEEHHCCCHHHCCCCCCCCCCCCEEECCCCCCCCCCCHH LEDLAKVKSIVVEAAKDVAVLNADDPNVLKMSAKVTAKHIFYVTMNPEHALVKQHIRAGG HHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEEEEEEEEEEEEECCCHHHHHHHHHCCC KACIIEKGVNGDMITIFDNHIHIPVLWTHLIPATMEGKAIHNVQNSMFAIAICYSMGMSL CEEEEEECCCCCEEEEECCEEEEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCH DDMRDGLRTFVTSFYQAPGRMNWFEEHPFKVLMDYGHNPAAIKLVSQMIMNMEFAGKKIC HHHHHHHHHHHHHHHCCCCCCCCHHHCCHHEEECCCCCHHHHHHHHHHHHHHHCCCCEEE VLASPGDRRDEDIAELAKTATPYYDYFICKRDDDTRGRAPDEVPRILKEALIEAGISADN EEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCC IEIIESEKEAVDAALNMAEEGDLVVIFADKLKRTWKQIIYFNKDQEFDGKDKKLEKQEMF EEEEECHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHH SASVIAQTPSLSEEISQVIKAGIISDDSGVRVVYHEEDND HHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCC >Mature Secondary Structure MKILSTNVYVGPNIYANFPVIRHEIDLGVLENWPSAKIGDKFIDQLVESLPGLQEHGCSY CEEEEEEEEECCCCEECCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCHHHHCCCC REKGGFIRRLREDEGTWMGHIWEHVILELQSMAGSDVTFGRTRSTGEVGHYNMVYEYKQK HHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCC DVGLRAMELARDLLISILPENLKKQVEFANEYFDFEYEKVKFIKFAQSKEFGPSTASLVE CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCCHHHHHH AAKKRDIPYIRLNDQSLVQFGYGKYQQRIRATITGKTTSIAVDLSCDKEQTNTILSSLGL HHHHCCCCEEEECCCHHHHHCHHHHHHHEEEEEECCEEEEEEEEECCCHHHHHHHHHCCC PVPKQRMVTTEEGAVRSAKILGFPLVVKPLDGNHGRGISINLKTIEEIKEAFVEANKVSR CCCHHHEEECCCCCCCEEEEECCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH YVLLEQYVIGFDHRMLVVDGKLIAVAKRVPGHVVGDGKHTIAELVEIVNQDPRRGIGHEK HHHHHHHHHCCCCEEEEECCCEEEEEHHCCCCEECCCHHHHHHHHHHHCCCCCCCCCHHH VLTKLELDYQARTLLRAAGYDENTILKDGEVFYLRSTANLSTGGTAIDVTDIVHPDNRDM HHHHHCCCHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCCCEEEEEECCCCCCHHH AERAIKAIGLDVGGVDFLIDDISQSYHDIGGAICECNAAPGFRMHVAPSEGKPRDVAGAV HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCCHHHHHH IDMLIPREYGNARIPIAAITGTNGKTTTSRMVAHMWKNAGKVVGLTTTDGVYINGKLTVA HHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEEEE GDTTGPASAQMVLKDPSVEMAILETARGGLLRSGLGYDYCNVGACLNISADHLGLKGINT CCCCCCCCCEEEEECCCCEEEEEEHHCCCHHHCCCCCCCCCCCCEEECCCCCCCCCCCHH LEDLAKVKSIVVEAAKDVAVLNADDPNVLKMSAKVTAKHIFYVTMNPEHALVKQHIRAGG HHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEEEEEEEEEEEEECCCHHHHHHHHHCCC KACIIEKGVNGDMITIFDNHIHIPVLWTHLIPATMEGKAIHNVQNSMFAIAICYSMGMSL CEEEEEECCCCCEEEEECCEEEEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCH DDMRDGLRTFVTSFYQAPGRMNWFEEHPFKVLMDYGHNPAAIKLVSQMIMNMEFAGKKIC HHHHHHHHHHHHHHHCCCCCCCCHHHCCHHEEECCCCCHHHHHHHHHHHHHHHCCCCEEE VLASPGDRRDEDIAELAKTATPYYDYFICKRDDDTRGRAPDEVPRILKEALIEAGISADN EEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCC IEIIESEKEAVDAALNMAEEGDLVVIFADKLKRTWKQIIYFNKDQEFDGKDKKLEKQEMF EEEEECHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHH SASVIAQTPSLSEEISQVIKAGIISDDSGVRVVYHEEDND HHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9652408 [H]