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The map label for this gene is pilQ [H]

Identifier: 89256170

GI number: 89256170

Start: 784469

End: 786241

Strand: Direct

Name: pilQ [H]

Synonym: FTL_0800

Alternate gene names: 89256170

Gene position: 784469-786241 (Clockwise)

Preceding gene: 89256169

Following gene: 89256171

Centisome position: 41.38

GC content: 35.31

Gene sequence:

>1773_bases
ATGTTTTTTGCAAAAAAGAAGTTATTAGTTGTTCTAACAATATTGGGTGGTATTCTAGGTTATGATGTCTCGGTAGCTGA
TACTAAAGAATCTCAAGTATCTAATCAGCCGCAAACTTCAGAGCAGCCTGTAGCCAAAATTGTTGGTCGAGAGGAAAATA
AAGATAAAGTTACTGATAAACATATCAAAAATCTTGAATTTCATCGTAGTTTAAATGGTAGTGCTGTTTTTGAAGTTGCT
TTTGAGGAGAATATAAGTAATTTTTCGGGCTATAAAACTAAGCTGTCACAAGATGGCTATACACTGACAATAACTTTTAA
TGATACCACTATATCGGATAAGTGGGTTAGTAATATTGATACTAAAGTTTTTAACACTATAGTTGATTCGATCAAGATTT
TTAAAGAAGGTGGAGGTGTCGTTTTTGTAATTCATTCTCTTGATAAAATTTCTCTAAGTGACTTCAAAGAAGGTAATATA
TTTAAGTTTAAAATTGATAGACGCAACAGCCGTGTTGAAGGATTTAATGTTAATGAGCCAATTTCAATATCTTTCAAAGA
TGCTCCAGTGCAGACTGTATTACAGGTGTTATCTGAATTTGCTGGTCTAAATCTAGTGGTTAGTAGTAGTGTGCGTGGTA
ATATTTCTATTGATCTAAAAAATGTGCCTTGGAATGAGGTGATGAATATTGTATTAGTCAGTAAAGGTCTAGCTACAAAA
AAAATGAGTAGTATATTATATGTAGCTACTGCCGCTGAAATTGCAGCTCAAGAGCAGTTAGAGTTACAAACAAAACGTTT
ATTGGAAAATAATGCTATCTTGGTGACAGAATTTATACCATTAAACTATACTACTGCTCAGGCTGCACAAACGGTTATTA
CTTCAATGGCAAAACAAAATGGTGGTATTATGTCACCCCGAGGTAGTATTACTGCGGATGCACGTACAAATACTTTAATA
GTAACAGATACCGAAGAAAAATTGCCGCGTATCAAAGAGGTTGTTAATGATATTGATATTCCAAATGATCAAGTTTTGAT
AGAAGCTAGAATAGTCGAAGTACTTAGAACAAGTGCACTTGAACTTGGCTTTAACTATGGTGTTGTTGATCCTTCTAGTA
GAGTTAATATAGGTCTATATACTTTTAATAGTAATCCTAATCCTGCTCCAGGACCAACTCCAACCCCAGTAGATACTTTT
GTTGGGACAACAGCAAAGCTAGCGTATACTATAGCTGGAGGAGTAAGGCTTGAGATGGAAGTCAGAGCTCTTGAGAGTGA
GTCACTAGCAGAAGAAGTGGCATCTCCACACCTAGTAGTTGCAAATAACCAAGTAGCATTTATCAAAGATGGTGAAGATG
TACCATATAACCAAGCAACAGCTTCTGGTGCCGCAGCTGTTGCTTTCCAAGAGGCGGTTTTAGAATTACAAGTTACGCCA
CAAATTGCTCCTGATGGTAATATTATTATGGATATTCTTGTTACTAAAAACTCAGTAGGAGCTTCTCCTGGTAAAACCCC
ACAAGGAGGTGATTTGCCACCAATTATCAAAAAGAGAGAGATAACCACCAAAGTTATGACCAAAGATGGTGATACTGTCG
TAATTGGTGGGATATACCAAAAAACCCAAAAAGAAGAGCGTAATAAAATCCCATTCTTAGGTGATATTCCTTATTTGGGT
TATCTATTTAGTTATACGAAAATTACTGATCAGGATTCTGAGTTGTTAATTTTTATAACTCCAAAAATCATTGAGTCAAG
AGTCCAAAAATGA

Upstream 100 bases:

>100_bases
TGTAACCAAAGAAGGTATTGTTATTGATGAGTGGAAGAAGGATGACCTCAAGAGAGTCTGGGAAAAGATTCAAACTGTTA
TACATTAGTAAGGTAAAGTG

Downstream 100 bases:

>100_bases
TAGCAGATAATAGTTGCAAAAATATCAATATTTAGGTATCTTATAGCCTATAATTTTTTATGTACAAGGGGTGATTAGTA
ACTAACTATCACGGTGTGTA

Product: Type IV pilin multimeric outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MFFAKKKLLVVLTILGGILGYDVSVADTKESQVSNQPQTSEQPVAKIVGREENKDKVTDKHIKNLEFHRSLNGSAVFEVA
FEENISNFSGYKTKLSQDGYTLTITFNDTTISDKWVSNIDTKVFNTIVDSIKIFKEGGGVVFVIHSLDKISLSDFKEGNI
FKFKIDRRNSRVEGFNVNEPISISFKDAPVQTVLQVLSEFAGLNLVVSSSVRGNISIDLKNVPWNEVMNIVLVSKGLATK
KMSSILYVATAAEIAAQEQLELQTKRLLENNAILVTEFIPLNYTTAQAAQTVITSMAKQNGGIMSPRGSITADARTNTLI
VTDTEEKLPRIKEVVNDIDIPNDQVLIEARIVEVLRTSALELGFNYGVVDPSSRVNIGLYTFNSNPNPAPGPTPTPVDTF
VGTTAKLAYTIAGGVRLEMEVRALESESLAEEVASPHLVVANNQVAFIKDGEDVPYNQATASGAAAVAFQEAVLELQVTP
QIAPDGNIIMDILVTKNSVGASPGKTPQGGDLPPIIKKREITTKVMTKDGDTVVIGGIYQKTQKEERNKIPFLGDIPYLG
YLFSYTKITDQDSELLIFITPKIIESRVQK

Sequences:

>Translated_590_residues
MFFAKKKLLVVLTILGGILGYDVSVADTKESQVSNQPQTSEQPVAKIVGREENKDKVTDKHIKNLEFHRSLNGSAVFEVA
FEENISNFSGYKTKLSQDGYTLTITFNDTTISDKWVSNIDTKVFNTIVDSIKIFKEGGGVVFVIHSLDKISLSDFKEGNI
FKFKIDRRNSRVEGFNVNEPISISFKDAPVQTVLQVLSEFAGLNLVVSSSVRGNISIDLKNVPWNEVMNIVLVSKGLATK
KMSSILYVATAAEIAAQEQLELQTKRLLENNAILVTEFIPLNYTTAQAAQTVITSMAKQNGGIMSPRGSITADARTNTLI
VTDTEEKLPRIKEVVNDIDIPNDQVLIEARIVEVLRTSALELGFNYGVVDPSSRVNIGLYTFNSNPNPAPGPTPTPVDTF
VGTTAKLAYTIAGGVRLEMEVRALESESLAEEVASPHLVVANNQVAFIKDGEDVPYNQATASGAAAVAFQEAVLELQVTP
QIAPDGNIIMDILVTKNSVGASPGKTPQGGDLPPIIKKREITTKVMTKDGDTVVIGGIYQKTQKEERNKIPFLGDIPYLG
YLFSYTKITDQDSELLIFITPKIIESRVQK
>Mature_590_residues
MFFAKKKLLVVLTILGGILGYDVSVADTKESQVSNQPQTSEQPVAKIVGREENKDKVTDKHIKNLEFHRSLNGSAVFEVA
FEENISNFSGYKTKLSQDGYTLTITFNDTTISDKWVSNIDTKVFNTIVDSIKIFKEGGGVVFVIHSLDKISLSDFKEGNI
FKFKIDRRNSRVEGFNVNEPISISFKDAPVQTVLQVLSEFAGLNLVVSSSVRGNISIDLKNVPWNEVMNIVLVSKGLATK
KMSSILYVATAAEIAAQEQLELQTKRLLENNAILVTEFIPLNYTTAQAAQTVITSMAKQNGGIMSPRGSITADARTNTLI
VTDTEEKLPRIKEVVNDIDIPNDQVLIEARIVEVLRTSALELGFNYGVVDPSSRVNIGLYTFNSNPNPAPGPTPTPVDTF
VGTTAKLAYTIAGGVRLEMEVRALESESLAEEVASPHLVVANNQVAFIKDGEDVPYNQATASGAAAVAFQEAVLELQVTP
QIAPDGNIIMDILVTKNSVGASPGKTPQGGDLPPIIKKREITTKVMTKDGDTVVIGGIYQKTQKEERNKIPFLGDIPYLG
YLFSYTKITDQDSELLIFITPKIIESRVQK

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=419, Percent_Identity=33.890214797136, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI87082242, Length=392, Percent_Identity=29.0816326530612, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 64494; Mature: 64494

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFAKKKLLVVLTILGGILGYDVSVADTKESQVSNQPQTSEQPVAKIVGREENKDKVTDK
CCCCHHHHHHHHHHHHHHHCCCEEECCCCHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHH
HIKNLEFHRSLNGSAVFEVAFEENISNFSGYKTKLSQDGYTLTITFNDTTISDKWVSNID
HHHCCHHHCCCCCCEEEEEEEHHCCCCCCCCEEEECCCCEEEEEEECCCCCCHHHHHHHH
TKVFNTIVDSIKIFKEGGGVVFVIHSLDKISLSDFKEGNIFKFKIDRRNSRVEGFNVNEP
HHHHHHHHHHHHHEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCC
ISISFKDAPVQTVLQVLSEFAGLNLVVSSSVRGNISIDLKNVPWNEVMNIVLVSKGLATK
EEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCHHHHHEEEEEECCCCHH
KMSSILYVATAAEIAAQEQLELQTKRLLENNAILVTEFIPLNYTTAQAAQTVITSMAKQN
HHHHEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHC
GGIMSPRGSITADARTNTLIVTDTEEKLPRIKEVVNDIDIPNDQVLIEARIVEVLRTSAL
CCEECCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
ELGFNYGVVDPSSRVNIGLYTFNSNPNPAPGPTPTPVDTFVGTTAKLAYTIAGGVRLEME
HCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHCCCHHEEEEEEECCEEEEEE
VRALESESLAEEVASPHLVVANNQVAFIKDGEDVPYNQATASGAAAVAFQEAVLELQVTP
EEHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCCCCCCCCCHHHHHHHHEEEEEEECC
QIAPDGNIIMDILVTKNSVGASPGKTPQGGDLPPIIKKREITTKVMTKDGDTVVIGGIYQ
CCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCHHH
KTQKEERNKIPFLGDIPYLGYLFSYTKITDQDSELLIFITPKIIESRVQK
HHHHHHHCCCCEEECCCHHHHHHHHEEECCCCCCEEEEECHHHHHHHHCC
>Mature Secondary Structure
MFFAKKKLLVVLTILGGILGYDVSVADTKESQVSNQPQTSEQPVAKIVGREENKDKVTDK
CCCCHHHHHHHHHHHHHHHCCCEEECCCCHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHH
HIKNLEFHRSLNGSAVFEVAFEENISNFSGYKTKLSQDGYTLTITFNDTTISDKWVSNID
HHHCCHHHCCCCCCEEEEEEEHHCCCCCCCCEEEECCCCEEEEEEECCCCCCHHHHHHHH
TKVFNTIVDSIKIFKEGGGVVFVIHSLDKISLSDFKEGNIFKFKIDRRNSRVEGFNVNEP
HHHHHHHHHHHHHEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCC
ISISFKDAPVQTVLQVLSEFAGLNLVVSSSVRGNISIDLKNVPWNEVMNIVLVSKGLATK
EEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCHHHHHEEEEEECCCCHH
KMSSILYVATAAEIAAQEQLELQTKRLLENNAILVTEFIPLNYTTAQAAQTVITSMAKQN
HHHHEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHC
GGIMSPRGSITADARTNTLIVTDTEEKLPRIKEVVNDIDIPNDQVLIEARIVEVLRTSAL
CCEECCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
ELGFNYGVVDPSSRVNIGLYTFNSNPNPAPGPTPTPVDTFVGTTAKLAYTIAGGVRLEME
HCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHCCCHHEEEEEEECCEEEEEE
VRALESESLAEEVASPHLVVANNQVAFIKDGEDVPYNQATASGAAAVAFQEAVLELQVTP
EEHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCCCCCCCCCHHHHHHHHEEEEEEECC
QIAPDGNIIMDILVTKNSVGASPGKTPQGGDLPPIIKKREITTKVMTKDGDTVVIGGIYQ
CCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCHHH
KTQKEERNKIPFLGDIPYLGYLFSYTKITDQDSELLIFITPKIIESRVQK
HHHHHHHCCCCEEECCCHHHHHHHHEEECCCCCCEEEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]