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The map label for this gene is xseA [H]

Identifier: 89256140

GI number: 89256140

Start: 746799

End: 748184

Strand: Direct

Name: xseA [H]

Synonym: FTL_0754

Alternate gene names: 89256140

Gene position: 746799-748184 (Clockwise)

Preceding gene: 89256138

Following gene: 89256141

Centisome position: 39.39

GC content: 30.59

Gene sequence:

>1386_bases
ATGCAACAATCACTAAAATTAAGCGAATTTCTTGAGCTTATAAAAAGTACTATAGAAATGAGTTTTGGCTATGAAGGTTT
CTGGATAGTTGCTGAATTATCTGAATGGCGTAAGTCTGGAAAACACTATTATGGCGAACTTATTGAGCATGATGGTATAA
GTAAATACCCTATTGCTAAAATTAGGTGTAATTGTTGGGCAAATAAAGCTGATTATATTCATAATAAGTTTAGCTTAGTA
ACTGGAGAAAAACTTAGTTCTGATATGAAAGTTCTAATGAAAGTTACAGTGAGTTATCATATCAGTTTTGGATTGAGTCT
AAATATTGTTGATATTGATCCAGCTTTTACACTTGGTGATAGACAAGCTCGTAAAATAGAAATTCTTGAGAAATTAGCTA
AAAAAGGTATCTTAGAAAAAAATAAGTCTCTAGCTATGCCTTATGATTTTACAAGTATAGCTGTGATTACCAGTATAACA
GCAGCAGGAAAGGGCGATTTTTTTGAGGAAGCGGATAAACTGCAAGATTTAGGACTATGTAATTTTGATATTTATGAGGC
AAAAATGCAAGGTGCAGAATGTGCTGAAAGTGTCTCTACAGCTTTTGCAAAAATAGAAGCTAAAGCATTTGATTATGATG
CTATAGTAGTAATCCGAGGCGGAGGGTCGCAAGCTGATCTTGATTGGTTTAATAATATCACACCTGCTGAAAGTATTTGT
AATAGTAAAATACCTGTAATGATTGGTATAGGACATGAGCGTGATACAACTGTTTTAGATGAGATATGTACCAAAAAGTT
TGATACACCATCTAAAGTGATAAATTTTATCGCAAATATAATTATAACTAATGCCAAAAATGCCAAGTATAACTATGCAG
ATATACTTAAGATTACTAATAATTCAGTAAAGCAAAATAAACATCAATTAGATAGTTTATACCATAATTTTAAAACTAAA
ATTGAGCATTATTTATATCAAACAAACCAAAATATTGAGCATAATTACAAAGCGACTATATCTATAGCTAGAGGATTGGT
GAAACTATATGGCAAGTCTATGGATATGCAGTATGATAATATAATTTCTAATTCGCAAAACCTTATAAAAAACTCTCAGC
ATAATCTTGAAGAGTCATATAATCATTCGCTAAGTATTGCTAAAAATGTTATAAAATATTACAATCAAGCAAGTGAATAT
TTATACAAGCAGATATTATCGATATCTATTGAACCTACTTTGAGAAGAGGGTTTAGCATAACTAAAACAAAAGATGGTAA
GTATATCACTAGCCAAAAGCAGGCACAAAAATATCTAAATTTAGAAATAATTTATGCAGATGGTCAAGTACAAGTAGAGG
TGAAAAATAATGGCAACGCAAACTAA

Upstream 100 bases:

>100_bases
AATTTAAGTATATGAATTTTTGGCAAATATTGATTAGACTTGTATATAACATTAATAAGTGTGAAAATTTATTAATTAGC
TTGATATATAAATCTTAAAT

Downstream 100 bases:

>100_bases
AAAATTCGCAAAAAACTATGAAATATTGGCAGAAATAAATGAGAAACTACAAGAGCAGCAAGACAATCCAGCATTATTAG
ATGAGCTAGCACCTATGCTT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MQQSLKLSEFLELIKSTIEMSFGYEGFWIVAELSEWRKSGKHYYGELIEHDGISKYPIAKIRCNCWANKADYIHNKFSLV
TGEKLSSDMKVLMKVTVSYHISFGLSLNIVDIDPAFTLGDRQARKIEILEKLAKKGILEKNKSLAMPYDFTSIAVITSIT
AAGKGDFFEEADKLQDLGLCNFDIYEAKMQGAECAESVSTAFAKIEAKAFDYDAIVVIRGGGSQADLDWFNNITPAESIC
NSKIPVMIGIGHERDTTVLDEICTKKFDTPSKVINFIANIIITNAKNAKYNYADILKITNNSVKQNKHQLDSLYHNFKTK
IEHYLYQTNQNIEHNYKATISIARGLVKLYGKSMDMQYDNIISNSQNLIKNSQHNLEESYNHSLSIAKNVIKYYNQASEY
LYKQILSISIEPTLRRGFSITKTKDGKYITSQKQAQKYLNLEIIYADGQVQVEVKNNGNAN

Sequences:

>Translated_461_residues
MQQSLKLSEFLELIKSTIEMSFGYEGFWIVAELSEWRKSGKHYYGELIEHDGISKYPIAKIRCNCWANKADYIHNKFSLV
TGEKLSSDMKVLMKVTVSYHISFGLSLNIVDIDPAFTLGDRQARKIEILEKLAKKGILEKNKSLAMPYDFTSIAVITSIT
AAGKGDFFEEADKLQDLGLCNFDIYEAKMQGAECAESVSTAFAKIEAKAFDYDAIVVIRGGGSQADLDWFNNITPAESIC
NSKIPVMIGIGHERDTTVLDEICTKKFDTPSKVINFIANIIITNAKNAKYNYADILKITNNSVKQNKHQLDSLYHNFKTK
IEHYLYQTNQNIEHNYKATISIARGLVKLYGKSMDMQYDNIISNSQNLIKNSQHNLEESYNHSLSIAKNVIKYYNQASEY
LYKQILSISIEPTLRRGFSITKTKDGKYITSQKQAQKYLNLEIIYADGQVQVEVKNNGNAN
>Mature_461_residues
MQQSLKLSEFLELIKSTIEMSFGYEGFWIVAELSEWRKSGKHYYGELIEHDGISKYPIAKIRCNCWANKADYIHNKFSLV
TGEKLSSDMKVLMKVTVSYHISFGLSLNIVDIDPAFTLGDRQARKIEILEKLAKKGILEKNKSLAMPYDFTSIAVITSIT
AAGKGDFFEEADKLQDLGLCNFDIYEAKMQGAECAESVSTAFAKIEAKAFDYDAIVVIRGGGSQADLDWFNNITPAESIC
NSKIPVMIGIGHERDTTVLDEICTKKFDTPSKVINFIANIIITNAKNAKYNYADILKITNNSVKQNKHQLDSLYHNFKTK
IEHYLYQTNQNIEHNYKATISIARGLVKLYGKSMDMQYDNIISNSQNLIKNSQHNLEESYNHSLSIAKNVIKYYNQASEY
LYKQILSISIEPTLRRGFSITKTKDGKYITSQKQAQKYLNLEIIYADGQVQVEVKNNGNAN

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=478, Percent_Identity=23.4309623430962, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579 [H]

Pfam domain/function: PF02601 Exonuc_VII_L [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 52246; Mature: 52246

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQSLKLSEFLELIKSTIEMSFGYEGFWIVAELSEWRKSGKHYYGELIEHDGISKYPIAK
CCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHCCCHHHHHHHHCCCCCCCCEEE
IRCNCWANKADYIHNKFSLVTGEKLSSDMKVLMKVTVSYHISFGLSLNIVDIDPAFTLGD
EEEEECCCCHHHHHCHHEEEECHHHHHHHHHHHHHHHEEEEEECEEEEEEECCCCEECCC
RQARKIEILEKLAKKGILEKNKSLAMPYDFTSIAVITSITAAGKGDFFEEADKLQDLGLC
CHHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
NFDIYEAKMQGAECAESVSTAFAKIEAKAFDYDAIVVIRGGGSQADLDWFNNITPAESIC
CCCHHHHHHCHHHHHHHHHHHHHHHHHEEECCEEEEEEECCCCCCCHHHHCCCCCHHHHH
NSKIPVMIGIGHERDTTVLDEICTKKFDTPSKVINFIANIIITNAKNAKYNYADILKITN
CCCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCCCCCHHHEEEECC
NSVKQNKHQLDSLYHNFKTKIEHYLYQTNQNIEHNYKATISIARGLVKLYGKSMDMQYDN
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
IISNSQNLIKNSQHNLEESYNHSLSIAKNVIKYYNQASEYLYKQILSISIEPTLRRGFSI
HHCCCHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCEEE
TKTKDGKYITSQKQAQKYLNLEIIYADGQVQVEVKNNGNAN
EECCCCCEECCHHHHHHHCCEEEEEECCEEEEEECCCCCCC
>Mature Secondary Structure
MQQSLKLSEFLELIKSTIEMSFGYEGFWIVAELSEWRKSGKHYYGELIEHDGISKYPIAK
CCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHCCCHHHHHHHHCCCCCCCCEEE
IRCNCWANKADYIHNKFSLVTGEKLSSDMKVLMKVTVSYHISFGLSLNIVDIDPAFTLGD
EEEEECCCCHHHHHCHHEEEECHHHHHHHHHHHHHHHEEEEEECEEEEEEECCCCEECCC
RQARKIEILEKLAKKGILEKNKSLAMPYDFTSIAVITSITAAGKGDFFEEADKLQDLGLC
CHHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
NFDIYEAKMQGAECAESVSTAFAKIEAKAFDYDAIVVIRGGGSQADLDWFNNITPAESIC
CCCHHHHHHCHHHHHHHHHHHHHHHHHEEECCEEEEEEECCCCCCCHHHHCCCCCHHHHH
NSKIPVMIGIGHERDTTVLDEICTKKFDTPSKVINFIANIIITNAKNAKYNYADILKITN
CCCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCCCCCHHHEEEECC
NSVKQNKHQLDSLYHNFKTKIEHYLYQTNQNIEHNYKATISIARGLVKLYGKSMDMQYDN
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
IISNSQNLIKNSQHNLEESYNHSLSIAKNVIKYYNQASEYLYKQILSISIEPTLRRGFSI
HHCCCHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCEEE
TKTKDGKYITSQKQAQKYLNLEIIYADGQVQVEVKNNGNAN
EECCCCCEECCHHHHHHHCCEEEEEECCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]