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The map label for this gene is ygfA [H]

Identifier: 89256113

GI number: 89256113

Start: 713713

End: 714261

Strand: Reverse

Name: ygfA [H]

Synonym: FTL_0724

Alternate gene names: 89256113

Gene position: 714261-713713 (Counterclockwise)

Preceding gene: 89256120

Following gene: 89256112

Centisome position: 37.67

GC content: 28.96

Gene sequence:

>549_bases
ATGGATAAAAATCAAATACGTAGAGAGCTTTTAAATATTAGAGATTCTCTTATAAACAAAACCTACCTTAGCGAGCAAAT
TAGTTCTAAACTAATAAGTTACATACAAGCAAATTTTACTAATCCTAAAATTGGTAGTTTTGCGTCGCTAAAAAATGAAA
TAGATACCCAAACTATTAATAATCACTTTGAAAATATATATTTACCTATAGTTCACCCTTTTATAAAACATGGGCTTTGG
TTTGCTAGAGATTCTAAGAAATATTATCTAAATAAATATAAAATCAAAGAACCAGTTTATTGCGTTAAAGATGTAGTTAC
AGCTTGGGAGCTAGATATTATTATCGTACCGATGGTTGGTTTTACTAGCGATAAATTTAGAATGGGCATGGGTGGAGGCT
TCTATGACTATAATCTAAGCTTTAAAAAAATACATAAATGGCCATTAACTATAGGTATAGCCTTTGATGAGCAGCAAAAT
AATGCTATTATCATAGATAAACATGACATTAAGCTTGATTTAATTATTACACCTACGAGGATATTATAA

Upstream 100 bases:

>100_bases
GCCCAACGTTGAAACTATGGTACCCACCTTGATACCATAGGGATCAAGAATATTGAACTAAAACGGTAATCTGGACAACT
AATTTTTTATACTTGAAGTC

Downstream 100 bases:

>100_bases
CTATGGATAGTACTACTGTAGCACAACAAATCAAAAATCAGATATTATCCAAAGTTGAACCTCAAGCTATAATCGAAATA
ATTGACGAAACACATAAGCA

Product: 5-formyltetrahydroformate cycloligase family protein

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MDKNQIRRELLNIRDSLINKTYLSEQISSKLISYIQANFTNPKIGSFASLKNEIDTQTINNHFENIYLPIVHPFIKHGLW
FARDSKKYYLNKYKIKEPVYCVKDVVTAWELDIIIVPMVGFTSDKFRMGMGGGFYDYNLSFKKIHKWPLTIGIAFDEQQN
NAIIIDKHDIKLDLIITPTRIL

Sequences:

>Translated_182_residues
MDKNQIRRELLNIRDSLINKTYLSEQISSKLISYIQANFTNPKIGSFASLKNEIDTQTINNHFENIYLPIVHPFIKHGLW
FARDSKKYYLNKYKIKEPVYCVKDVVTAWELDIIIVPMVGFTSDKFRMGMGGGFYDYNLSFKKIHKWPLTIGIAFDEQQN
NAIIIDKHDIKLDLIITPTRIL
>Mature_182_residues
MDKNQIRRELLNIRDSLINKTYLSEQISSKLISYIQANFTNPKIGSFASLKNEIDTQTINNHFENIYLPIVHPFIKHGLW
FARDSKKYYLNKYKIKEPVYCVKDVVTAWELDIIIVPMVGFTSDKFRMGMGGGFYDYNLSFKKIHKWPLTIGIAFDEQQN
NAIIIDKHDIKLDLIITPTRIL

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Escherichia coli, GI1789278, Length=165, Percent_Identity=30.3030303030303, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: 6.3.3.2

Molecular weight: Translated: 21289; Mature: 21289

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKNQIRRELLNIRDSLINKTYLSEQISSKLISYIQANFTNPKIGSFASLKNEIDTQTIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
NHFENIYLPIVHPFIKHGLWFARDSKKYYLNKYKIKEPVYCVKDVVTAWELDIIIVPMVG
HHHCEEEHHHHHHHHHCCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHEEEEEEEEEEC
FTSDKFRMGMGGGFYDYNLSFKKIHKWPLTIGIAFDEQQNNAIIIDKHDIKLDLIITPTR
CCCCCEEECCCCCEEEECCCHHHEECCEEEEEEEEECCCCCEEEEECCCEEEEEEECCCC
IL
CC
>Mature Secondary Structure
MDKNQIRRELLNIRDSLINKTYLSEQISSKLISYIQANFTNPKIGSFASLKNEIDTQTIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
NHFENIYLPIVHPFIKHGLWFARDSKKYYLNKYKIKEPVYCVKDVVTAWELDIIIVPMVG
HHHCEEEHHHHHHHHHCCEEEEECCCEEEEEEECCCCCHHHHHHHHHHHEEEEEEEEEEC
FTSDKFRMGMGGGFYDYNLSFKKIHKWPLTIGIAFDEQQNNAIIIDKHDIKLDLIITPTR
CCCCCEEECCCCCEEEECCCHHHEECCEEEEEEEEECCCCCEEEEECCCEEEEEEECCCC
IL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]