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The map label for this gene is cdr [H]

Identifier: 89256026

GI number: 89256026

Start: 621339

End: 621959

Strand: Direct

Name: cdr [H]

Synonym: FTL_0635

Alternate gene names: 89256026

Gene position: 621339-621959 (Clockwise)

Preceding gene: 89256025

Following gene: 89256027

Centisome position: 32.77

GC content: 34.46

Gene sequence:

>621_bases
ATGACTCCGGAGAAGTTTGATAAACAATATAATATCGATGCACGTACAAACTCTGAGGTTATAGCTATTGATAGGATAAA
TAAGCTCGTAACTGTTATAAATCACCATAGTGGTGACAAATATAGCGAAAGTTATGATAAGTTAATCTTGGCTGTTGGAG
CTAAGCTGATAGTGCCACCATTTAAGGGGTTAGAGACTATTGAGCATTTTATCCTTAGAAATGTTGTTGATGTCAAAAAG
ATTCATCAAGCAGTTTTTGATAAACAAAAGCCTGTCAAAGATATAACAGTAATTGGCGCTGGCTTTATCGGTGTTGAGGT
TGCAGAAAATCTCAAAGAAAAAGGCTTTAATGTAACTATAATCGAGATGGCTAATCAGATTATGCGACCTTTTGATTATG
AAATGGCAAAATTCTTAGAGAAAGAGCTACTAGATAATAGTGTTAATCTACTACTTGGTGAAAAAGTTGTTGGCTTTGAA
TCTGATAAGGTCTTACTTGAGTCAGGTAAAGAGATAAAAACCGATTTGGCTATTTTGGCTATAGGTGTTGCGCCAGATAC
TAACTTCCTAAAAGAAGTAGGTATTGATTTAGCAAAAACTGGTCATATTCATTGTAAATGA

Upstream 100 bases:

>100_bases
GATTATCATATTTGAGAAAGGTCCACATGTGTCATTCTAAAACTGTGGTTTACCATATCATCTAGGTGGTTATATTGAGA
CAGCTGAAAAGCTGATTTTG

Downstream 100 bases:

>100_bases
TAACTATCAAACATCTGATGAAAATATCTATGCCGCTGGTGATGCTATTTTGGTCAAAAATGCTCTTACATCTCAGGATT
TCAATTTACCTTTGGCAGGT

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MTPEKFDKQYNIDARTNSEVIAIDRINKLVTVINHHSGDKYSESYDKLILAVGAKLIVPPFKGLETIEHFILRNVVDVKK
IHQAVFDKQKPVKDITVIGAGFIGVEVAENLKEKGFNVTIIEMANQIMRPFDYEMAKFLEKELLDNSVNLLLGEKVVGFE
SDKVLLESGKEIKTDLAILAIGVAPDTNFLKEVGIDLAKTGHIHCK

Sequences:

>Translated_206_residues
MTPEKFDKQYNIDARTNSEVIAIDRINKLVTVINHHSGDKYSESYDKLILAVGAKLIVPPFKGLETIEHFILRNVVDVKK
IHQAVFDKQKPVKDITVIGAGFIGVEVAENLKEKGFNVTIIEMANQIMRPFDYEMAKFLEKELLDNSVNLLLGEKVVGFE
SDKVLLESGKEIKTDLAILAIGVAPDTNFLKEVGIDLAKTGHIHCK
>Mature_205_residues
TPEKFDKQYNIDARTNSEVIAIDRINKLVTVINHHSGDKYSESYDKLILAVGAKLIVPPFKGLETIEHFILRNVVDVKKI
HQAVFDKQKPVKDITVIGAGFIGVEVAENLKEKGFNVTIIEMANQIMRPFDYEMAKFLEKELLDNSVNLLLGEKVVGFES
DKVLLESGKEIKTDLAILAIGVAPDTNFLKEVGIDLAKTGHIHCK

Specific function: Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=210, Percent_Identity=29.0476190476191, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI226437568, Length=210, Percent_Identity=29.0476190476191, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI65787454, Length=210, Percent_Identity=29.0476190476191, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1789065, Length=203, Percent_Identity=26.6009852216749, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788892, Length=200, Percent_Identity=24.5, Blast_Score=70, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17559934, Length=210, Percent_Identity=30.952380952381, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24639257, Length=207, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI281359715, Length=207, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI281359713, Length=207, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24639250, Length=207, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI18543267, Length=207, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24639252, Length=207, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 23017; Mature: 22886

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPEKFDKQYNIDARTNSEVIAIDRINKLVTVINHHSGDKYSESYDKLILAVGAKLIVPP
CCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHCCCC
FKGLETIEHFILRNVVDVKKIHQAVFDKQKPVKDITVIGAGFIGVEVAENLKEKGFNVTI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEH
IEMANQIMRPFDYEMAKFLEKELLDNSVNLLLGEKVVGFESDKVLLESGKEIKTDLAILA
HHHHHHHHCCCCHHHHHHHHHHHHCCCHHEEECCEEECCCCCHHHHHCCCHHHHCEEEEE
IGVAPDTNFLKEVGIDLAKTGHIHCK
EECCCCHHHHHHHCCCHHCCCCCCCC
>Mature Secondary Structure 
TPEKFDKQYNIDARTNSEVIAIDRINKLVTVINHHSGDKYSESYDKLILAVGAKLIVPP
CCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHCCCC
FKGLETIEHFILRNVVDVKKIHQAVFDKQKPVKDITVIGAGFIGVEVAENLKEKGFNVTI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEH
IEMANQIMRPFDYEMAKFLEKELLDNSVNLLLGEKVVGFESDKVLLESGKEIKTDLAILA
HHHHHHHHCCCCHHHHHHHHHHHHCCCHHEEECCEEECCCCCHHHHHCCCHHHHCEEEEE
IGVAPDTNFLKEVGIDLAKTGHIHCK
EECCCCHHHHHHHCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA