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The map label for this gene is cfa [H]

Identifier: 89255965

GI number: 89255965

Start: 542406

End: 543500

Strand: Reverse

Name: cfa [H]

Synonym: FTL_0561

Alternate gene names: 89255965

Gene position: 543500-542406 (Counterclockwise)

Preceding gene: 89255966

Following gene: 89255964

Centisome position: 28.67

GC content: 33.88

Gene sequence:

>1095_bases
TTGACTCCTCCTGAAGGAGAAACAATATATACCAAAGGTGCAAAACCAGGACCAATAGCAGATTTAAAACTCAAGGATTG
GCGTACAGTTGTCAACCTTAAGCTCAAATCAGATATTGGCTTTGCTGCTGATTATCGCGATGGCTATTGGGAGACTTCTG
ATCTTAAATCCCTCATACATCTAGGCTTAGAGAATGAAGAAGCTTTTGGACAGTATATGAAACCAAATATTTTCTTCAAA
TTTTTTCAAAAACTTGGCTACTTGACTAAAAGAAATAGTATCAAACAAAGTAAAAAAAATATCTATGATCATTATGACTT
GGGTAATGATTTTTATAGCTTATGGTTAGATAGAACTATGACTTACTCTTCTGCTTTGTACAAAAATGAAAATGAAACAT
TAGAACAAGCACAAATTAATAAATACAAAAATATAATTGATAAGTTCGACAAAAAAGACGGTTCTATAATCGAGGTAGGT
TGTGGTTGGGGTGGTTTTGCTGAAACAGCTCTAACTAGTGGTAACTACTCCCTCAAAGGTATTACACTTTCTGAAGAGCA
ACATGCTTACGCTAAAAAGCGCTTAGCTGGCAAAAATGCTGAAATTGTAATCGAAGACTACCGCATCCAGACTGGCAAAT
ATGATTATATTGTCTCTATTGAGATGATCGAGGCTGGTGGTAGAGAATATTGGAATACATATTTTTCAAAGCTTAAATCA
CTACTTAAAGAAGATGGTAAAATTATCATTCAAGCAATAGTTATCGATGATAAGCTCTTTACTGACTATGCTAAAGGTAC
TGATATGATTAGAACCTTTATCTTCCCAGGTGGTTTTCTGCCATCTATGGAGCAAATTAATCTTGAACTTGATAAAGTTA
ACTTAAAATGTGTTGGTAAAGAATCTTTTGCTAAAGATTATGCAAAAACTCTTGATGAATGGGATAGAAATTTTGTAAAT
GTTGAGCAAGAACTTATAAAACTAGGTTTCGATAAGCGTTTTCAAAGAATGTGGCGTTTTTATATAAACTCTTGTAGTGC
TGCATTCACACATGGTCGTATTGATGTTGTACAACTGGAGATTGTTCATGCTTAG

Upstream 100 bases:

>100_bases
ATAGAAGATACTAACCGATAGTTTTTTTAAGATATGTTTGAGAAAATAGTAAAAAAAACTACTCGAATCACTAGATAAAA
TTGATTATAGTGAACTATAT

Downstream 100 bases:

>100_bases
GAAACTGCTAATAATTATTTTTATTAGTTTACCTTTATTTGGTGTGGCTGAAGAACTAACTTTACAACAAATAAAATCAC
AACAAGTTGGTAAAGTACAT

Product: cyclopropane-fatty-acid-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MTPPEGETIYTKGAKPGPIADLKLKDWRTVVNLKLKSDIGFAADYRDGYWETSDLKSLIHLGLENEEAFGQYMKPNIFFK
FFQKLGYLTKRNSIKQSKKNIYDHYDLGNDFYSLWLDRTMTYSSALYKNENETLEQAQINKYKNIIDKFDKKDGSIIEVG
CGWGGFAETALTSGNYSLKGITLSEEQHAYAKKRLAGKNAEIVIEDYRIQTGKYDYIVSIEMIEAGGREYWNTYFSKLKS
LLKEDGKIIIQAIVIDDKLFTDYAKGTDMIRTFIFPGGFLPSMEQINLELDKVNLKCVGKESFAKDYAKTLDEWDRNFVN
VEQELIKLGFDKRFQRMWRFYINSCSAAFTHGRIDVVQLEIVHA

Sequences:

>Translated_364_residues
MTPPEGETIYTKGAKPGPIADLKLKDWRTVVNLKLKSDIGFAADYRDGYWETSDLKSLIHLGLENEEAFGQYMKPNIFFK
FFQKLGYLTKRNSIKQSKKNIYDHYDLGNDFYSLWLDRTMTYSSALYKNENETLEQAQINKYKNIIDKFDKKDGSIIEVG
CGWGGFAETALTSGNYSLKGITLSEEQHAYAKKRLAGKNAEIVIEDYRIQTGKYDYIVSIEMIEAGGREYWNTYFSKLKS
LLKEDGKIIIQAIVIDDKLFTDYAKGTDMIRTFIFPGGFLPSMEQINLELDKVNLKCVGKESFAKDYAKTLDEWDRNFVN
VEQELIKLGFDKRFQRMWRFYINSCSAAFTHGRIDVVQLEIVHA
>Mature_363_residues
TPPEGETIYTKGAKPGPIADLKLKDWRTVVNLKLKSDIGFAADYRDGYWETSDLKSLIHLGLENEEAFGQYMKPNIFFKF
FQKLGYLTKRNSIKQSKKNIYDHYDLGNDFYSLWLDRTMTYSSALYKNENETLEQAQINKYKNIIDKFDKKDGSIIEVGC
GWGGFAETALTSGNYSLKGITLSEEQHAYAKKRLAGKNAEIVIEDYRIQTGKYDYIVSIEMIEAGGREYWNTYFSKLKSL
LKEDGKIIIQAIVIDDKLFTDYAKGTDMIRTFIFPGGFLPSMEQINLELDKVNLKCVGKESFAKDYAKTLDEWDRNFVNV
EQELIKLGFDKRFQRMWRFYINSCSAAFTHGRIDVVQLEIVHA

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=365, Percent_Identity=31.7808219178082, Blast_Score=162, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI133904226, Length=280, Percent_Identity=39.6428571428571, Blast_Score=195, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 42040; Mature: 41909

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPEGETIYTKGAKPGPIADLKLKDWRTVVNLKLKSDIGFAADYRDGYWETSDLKSLIH
CCCCCCCEEEECCCCCCCCCCCEECCCEEEEEEEEECCCCEEECCCCCCCCHHHHHHHHH
LGLENEEAFGQYMKPNIFFKFFQKLGYLTKRNSIKQSKKNIYDHYDLGNDFYSLWLDRTM
CCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCHHHHHHHHHHH
TYSSALYKNENETLEQAQINKYKNIIDKFDKKDGSIIEVGCGWGGFAETALTSGNYSLKG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHEECCCEEEEE
ITLSEEQHAYAKKRLAGKNAEIVIEDYRIQTGKYDYIVSIEMIEAGGREYWNTYFSKLKS
EEECCHHHHHHHHHHCCCCCEEEEEEEEEECCCEEEEEEEEEEECCCHHHHHHHHHHHHH
LLKEDGKIIIQAIVIDDKLFTDYAKGTDMIRTFIFPGGFLPSMEQINLELDKVNLKCVGK
HHHCCCEEEEEEEEECCHHHHHHHCCHHHHHHHHCCCCCCCCHHHHEEEEEEEEEEEECC
ESFAKDYAKTLDEWDRNFVNVEQELIKLGFDKRFQRMWRFYINSCSAAFTHGRIDVVQLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
IVHA
EECC
>Mature Secondary Structure 
TPPEGETIYTKGAKPGPIADLKLKDWRTVVNLKLKSDIGFAADYRDGYWETSDLKSLIH
CCCCCCEEEECCCCCCCCCCCEECCCEEEEEEEEECCCCEEECCCCCCCCHHHHHHHHH
LGLENEEAFGQYMKPNIFFKFFQKLGYLTKRNSIKQSKKNIYDHYDLGNDFYSLWLDRTM
CCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCHHHHHHHHHHH
TYSSALYKNENETLEQAQINKYKNIIDKFDKKDGSIIEVGCGWGGFAETALTSGNYSLKG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHEECCCEEEEE
ITLSEEQHAYAKKRLAGKNAEIVIEDYRIQTGKYDYIVSIEMIEAGGREYWNTYFSKLKS
EEECCHHHHHHHHHHCCCCCEEEEEEEEEECCCEEEEEEEEEEECCCHHHHHHHHHHHHH
LLKEDGKIIIQAIVIDDKLFTDYAKGTDMIRTFIFPGGFLPSMEQINLELDKVNLKCVGK
HHHCCCEEEEEEEEECCHHHHHHHCCHHHHHHHHCCCCCCCCHHHHEEEEEEEEEEEECC
ESFAKDYAKTLDEWDRNFVNVEQELIKLGFDKRFQRMWRFYINSCSAAFTHGRIDVVQLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
IVHA
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]