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The map label for this gene is fabG [C]

Identifier: 89255962

GI number: 89255962

Start: 540620

End: 541363

Strand: Reverse

Name: fabG [C]

Synonym: FTL_0558

Alternate gene names: 89255962

Gene position: 541363-540620 (Counterclockwise)

Preceding gene: 89255963

Following gene: 89255961

Centisome position: 28.55

GC content: 32.12

Gene sequence:

>744_bases
ATGCAAAAATTTGTAGGTAAAACGATCTGGATAATTGGCGCTACAGATGGAATAGGCAAAGCAGTCCTAAAAAAACTTGA
TAATTCAATACAAGCTGATTTTATAATATCTGCACGTTCGCTAGATAAACTACAAAACATAGCAGCTAATCTTAAAAATA
CCGCTCATGTACTAAGCTTTGATGTCGCTGACTTTGCAGAATTTGAAAAAGTAGCAGCTAGTGCTCTTAACTATAAGCCT
GATTTTATTATATACTTTCCTGCATTTTATGAGCCATCATTAATTGCTGATATTGCAATCGCCAATCTTAACAAGACTAT
CCAAACTAATTTAACTGCTGTTTTCTACTTGATAAGATTTGTACTACCTTTTCTAAAGAAAAATCCTCATTGTCAACTTG
CAATAACAGCAAGTGTTGCAGGCTATATTGGTCTACCAAGATCACAACCATACGCTGCTACTAAAGCTGGTGTAATAAAC
TTAGTTGAGAATCTCAAAACTGAAAATCCAGAGATTGATATTCGCCTAATTAATCCTAGCTTTGTTAAAACTAAGCTTAC
TGATAAAAATAATTTCAAAATGCCATCTCTATTAAAACCAGAACAATCCGCTGATAGTATTATCAAAGGCTTACAAACAA
GTAAATTTGAGATTCACTTTACAAAAAAATTCACTATAATTCTAAAACTTATTGCAGCACTACCATATAAGCTATATTTC
AAGATTGCTAAGAAAATGATCTAA

Upstream 100 bases:

>100_bases
AATGATAGCGTACTTATAAATAAAAACTCATTTAAGAAGTTTGGTTTGACTGTAGGTTCTTTAACATTATTCATGCATAA
GGAAAAAACAGGAGCATAAG

Downstream 100 bases:

>100_bases
AACTGGAGAAATCATGGAAACACAGTCTAATAAATTGACAATAGTAGCATTTGCTATTATGCACTTAGCCTGCTTGGCAA
TATTTTTTTAAATTATAATA

Product: oxidoreductase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MQKFVGKTIWIIGATDGIGKAVLKKLDNSIQADFIISARSLDKLQNIAANLKNTAHVLSFDVADFAEFEKVAASALNYKP
DFIIYFPAFYEPSLIADIAIANLNKTIQTNLTAVFYLIRFVLPFLKKNPHCQLAITASVAGYIGLPRSQPYAATKAGVIN
LVENLKTENPEIDIRLINPSFVKTKLTDKNNFKMPSLLKPEQSADSIIKGLQTSKFEIHFTKKFTIILKLIAALPYKLYF
KIAKKMI

Sequences:

>Translated_247_residues
MQKFVGKTIWIIGATDGIGKAVLKKLDNSIQADFIISARSLDKLQNIAANLKNTAHVLSFDVADFAEFEKVAASALNYKP
DFIIYFPAFYEPSLIADIAIANLNKTIQTNLTAVFYLIRFVLPFLKKNPHCQLAITASVAGYIGLPRSQPYAATKAGVIN
LVENLKTENPEIDIRLINPSFVKTKLTDKNNFKMPSLLKPEQSADSIIKGLQTSKFEIHFTKKFTIILKLIAALPYKLYF
KIAKKMI
>Mature_247_residues
MQKFVGKTIWIIGATDGIGKAVLKKLDNSIQADFIISARSLDKLQNIAANLKNTAHVLSFDVADFAEFEKVAASALNYKP
DFIIYFPAFYEPSLIADIAIANLNKTIQTNLTAVFYLIRFVLPFLKKNPHCQLAITASVAGYIGLPRSQPYAATKAGVIN
LVENLKTENPEIDIRLINPSFVKTKLTDKNNFKMPSLLKPEQSADSIIKGLQTSKFEIHFTKKFTIILKLIAALPYKLYF
KIAKKMI

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI210032110, Length=241, Percent_Identity=23.2365145228216, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=188, Percent_Identity=29.2553191489362, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=252, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 27572; Mature: 27572

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKFVGKTIWIIGATDGIGKAVLKKLDNSIQADFIISARSLDKLQNIAANLKNTAHVLSF
CCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHEEE
DVADFAEFEKVAASALNYKPDFIIYFPAFYEPSLIADIAIANLNKTIQTNLTAVFYLIRF
CHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VLPFLKKNPHCQLAITASVAGYIGLPRSQPYAATKAGVINLVENLKTENPEIDIRLINPS
HHHHHCCCCCEEEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCC
FVKTKLTDKNNFKMPSLLKPEQSADSIIKGLQTSKFEIHFTKKFTIILKLIAALPYKLYF
CEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHCCHHHHH
KIAKKMI
HHHHHCC
>Mature Secondary Structure
MQKFVGKTIWIIGATDGIGKAVLKKLDNSIQADFIISARSLDKLQNIAANLKNTAHVLSF
CCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHEEE
DVADFAEFEKVAASALNYKPDFIIYFPAFYEPSLIADIAIANLNKTIQTNLTAVFYLIRF
CHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VLPFLKKNPHCQLAITASVAGYIGLPRSQPYAATKAGVINLVENLKTENPEIDIRLINPS
HHHHHCCCCCEEEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCC
FVKTKLTDKNNFKMPSLLKPEQSADSIIKGLQTSKFEIHFTKKFTIILKLIAALPYKLYF
CEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHCCHHHHH
KIAKKMI
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA