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The map label for this gene is minD [H]

Identifier: 89255926

GI number: 89255926

Start: 499758

End: 500582

Strand: Reverse

Name: minD [H]

Synonym: FTL_0519

Alternate gene names: 89255926

Gene position: 500582-499758 (Counterclockwise)

Preceding gene: 89255927

Following gene: 89255925

Centisome position: 26.4

GC content: 35.27

Gene sequence:

>825_bases
ATGAGTGAAAAAAAACAAGGCAAGGTATTTGTAGTAACTTCTGGTAAAGGTGGTGTTGGTAAAACTACTTCAAGTGCCGC
TGTTGCATATGCTTTTGCTAAAAAAGGCCTTAAAACAGTTGTTATTGACTTTGATGTTGGTTTAAGAAATCTTGATCTTA
TTATGGGATGTGAAAGAAGAGTTGTTTATGATTTGATAAACGTTGTCAGAGAAGAAGCAACTATAAATCAAGCTATTATC
AAAGATAAAAGAATTGATGATTTATACATTATTCCAGCATCACAGACTAGAGATAAAGATGCTCTAACTGAAGAAGGTGT
TGACAGACTCATTGAAGAATTAAGAAACTCTTTTGATATTGTTTTATGCGATTCTCCAGCAGGTATTGAGAAAGGTTCGC
TAATGGCTATGAGATGTGCAGATGCTGCAATTATAGTCACTAACCCTGAAGTATCATCTGTTAGAGACTCTGATAGAATA
CTCGGTATGCTTTCTAGCAAAACTCTTAAAGCTCAAAGAGAAGGTGAATTCAAAGAGATTCATCTACTTCTTAATAGATA
TGATGCTGCTAGAGCCAGAGCCGGTGCGATGCTTAAGGCTGAAGACGTTAGTGAAATACTATATACCCCTATTGTTGGTA
TCATTCCAGAGTCTAAAGATATTCTAGAGGCTTCAAATAGTGGTCATCCAATTACACACTTTAGTGACTCGATTGCTGCT
AAAGCTTATTTCGATGCTGTGGATAGAATACTTGGTAAAGACGTACCAATGAGATATACTGAACAAAAGACTAGTTTCTT
CAAAAAATTGATAGGTAAATCATAA

Upstream 100 bases:

>100_bases
TAACACAGATGGGTATATAGTCTATCTACAAGATGACAAGATACATATAGAAGGTTTTTAATTTTTAAAGAAATTTAAAT
GAAAGAGGCTTAGGCTAAAA

Downstream 100 bases:

>100_bases
TTATGCTAGCTAAACTTTTTGGATTAAGTAAAAAACAACAGAGTGCTTCAGTAGCTAAAGAAAGGCTACAGATCATTGTT
GCTCATCAAAGAAGTGAGTT

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSEKKQGKVFVVTSGKGGVGKTTSSAAVAYAFAKKGLKTVVIDFDVGLRNLDLIMGCERRVVYDLINVVREEATINQAII
KDKRIDDLYIIPASQTRDKDALTEEGVDRLIEELRNSFDIVLCDSPAGIEKGSLMAMRCADAAIIVTNPEVSSVRDSDRI
LGMLSSKTLKAQREGEFKEIHLLLNRYDAARARAGAMLKAEDVSEILYTPIVGIIPESKDILEASNSGHPITHFSDSIAA
KAYFDAVDRILGKDVPMRYTEQKTSFFKKLIGKS

Sequences:

>Translated_274_residues
MSEKKQGKVFVVTSGKGGVGKTTSSAAVAYAFAKKGLKTVVIDFDVGLRNLDLIMGCERRVVYDLINVVREEATINQAII
KDKRIDDLYIIPASQTRDKDALTEEGVDRLIEELRNSFDIVLCDSPAGIEKGSLMAMRCADAAIIVTNPEVSSVRDSDRI
LGMLSSKTLKAQREGEFKEIHLLLNRYDAARARAGAMLKAEDVSEILYTPIVGIIPESKDILEASNSGHPITHFSDSIAA
KAYFDAVDRILGKDVPMRYTEQKTSFFKKLIGKS
>Mature_273_residues
SEKKQGKVFVVTSGKGGVGKTTSSAAVAYAFAKKGLKTVVIDFDVGLRNLDLIMGCERRVVYDLINVVREEATINQAIIK
DKRIDDLYIIPASQTRDKDALTEEGVDRLIEELRNSFDIVLCDSPAGIEKGSLMAMRCADAAIIVTNPEVSSVRDSDRIL
GMLSSKTLKAQREGEFKEIHLLLNRYDAARARAGAMLKAEDVSEILYTPIVGIIPESKDILEASNSGHPITHFSDSIAAK
AYFDAVDRILGKDVPMRYTEQKTSFFKKLIGKS

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=267, Percent_Identity=60.2996254681648, Blast_Score=323, Evalue=5e-90,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 30121; Mature: 29990

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKKQGKVFVVTSGKGGVGKTTSSAAVAYAFAKKGLKTVVIDFDVGLRNLDLIMGCERR
CCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCHH
VVYDLINVVREEATINQAIIKDKRIDDLYIIPASQTRDKDALTEEGVDRLIEELRNSFDI
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEE
VLCDSPAGIEKGSLMAMRCADAAIIVTNPEVSSVRDSDRILGMLSSKTLKAQREGEFKEI
EEECCCCCCCCCCEEEEEECCEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHCCCHHHH
HLLLNRYDAARARAGAMLKAEDVSEILYTPIVGIIPESKDILEASNSGHPITHFSDSIAA
HHHHHHHHHHHHHHCCEEEHHHHHHHHHHCHHEECCCCHHHHHCCCCCCCCCCCCHHHHH
KAYFDAVDRILGKDVPMRYTEQKTSFFKKLIGKS
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEKKQGKVFVVTSGKGGVGKTTSSAAVAYAFAKKGLKTVVIDFDVGLRNLDLIMGCERR
CCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCHH
VVYDLINVVREEATINQAIIKDKRIDDLYIIPASQTRDKDALTEEGVDRLIEELRNSFDI
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEE
VLCDSPAGIEKGSLMAMRCADAAIIVTNPEVSSVRDSDRILGMLSSKTLKAQREGEFKEI
EEECCCCCCCCCCEEEEEECCEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHCCCHHHH
HLLLNRYDAARARAGAMLKAEDVSEILYTPIVGIIPESKDILEASNSGHPITHFSDSIAA
HHHHHHHHHHHHHHCCEEEHHHHHHHHHHCHHEECCCCHHHHHCCCCCCCCCCCCHHHHH
KAYFDAVDRILGKDVPMRYTEQKTSFFKKLIGKS
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]