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The map label for this gene is ydgK [H]

Identifier: 89054417

GI number: 89054417

Start: 1914397

End: 1915587

Strand: Reverse

Name: ydgK [H]

Synonym: Jann_1926

Alternate gene names: 89054417

Gene position: 1915587-1914397 (Counterclockwise)

Preceding gene: 89054418

Following gene: 89054416

Centisome position: 44.36

GC content: 68.85

Gene sequence:

>1191_bases
ATGATAGCCACGCCCGCAAAGACCCCGCCCCGGCTTGTCACGCTGATCCTGCTGGCGGCGCTGTCGACGATGACGCTCAA
CATGATCCTGCCCTCGCTTGCGGCCATCGCCCGCACCTTTGAGGCGGAATATGCCGTGGCGAGCCTTGCGATCGGCGGCT
ATCTGGCCGTGACCGCCGTGGTGCAGCTGGTCGTGGGGCCGCTCTCGGACCGGATCGGGCGGCGGCCGGTGCTCTTGGGG
GGCTTGGTCATCTTCATCCTGGCCTCCGTCCTCTGCATGGTGGCGCAAAACATCTGGGTGTTCCTGGCCGCCCGTATGGC
CCAGAGCGCCATGTCGATGGGCTACGCGATCTCCCTCGCCGTCGTGCGCGACACGACCGAGCCCCGCCGCGCCGCCTCGG
TCATCGGCACAATCGGGACGATCATGGCGATCGCGCCGATCCTGGGACCGGTCCTGGGCGGCGTGCTGGACACGTATCTG
GGTTGGCGGGCGAGCTTCGTCGTCTATGCGCTCGCGGGCCTCGCCATGCTGGCCTGGTGCTGGGTGGATCTGGGGGAAAC
GCGCCCCGAGCGGGCCGATGCGCGCCCCTCAGCGGTCTCTGCGGCGCGCACGCTCCTGCGCCTGCCCGCCTTCCGCGCCT
ATCTGGCCTGCACCGCGCTTTCCACCGGCGGCTTCTTCGCCTTTCTTGCGGGCGTCCCCTTCGTGGCGACCGAGACGTTC
GGCATCACCACCGCACGCCTTGGGTTTTTCATCGGCTCAATCACTGCGGGGTATATGGCGGGCAGTTTCATCTCATCCCG
GCTCGCGTCGGGCCTTGCGCTGTCGACGATGATGCTGGCGGGCCGGATCGTGGCCTGTACCGGGCTAACATGCGGCTTGA
TCGCGCTGGCCTTCGGGATCGTCACCCCCCTCACCTTCTTCGGCAGCACGATCTGTGTGGGTATGGGCAACGGCCTGACC
ATGCCGTCCAGCAATGCGGGTGCCATGTCCGTGCGGCCCGAGCTTGCGGGCAGTGCGGCGGGCTTCACCGGGGCCGCCAC
CGTGGCCTGCGGCGCGATCCTGACCAGCGTCGCGGGGATCATCGTCCCCGGCCCCCATGCGCCCGCCACCGTCCTCGCGC
TTATGCTGGCGGCGTCGCTTGCCGCACTTGTGGCCGCACTCGCCGCCCGTCGGCACGAAACGACACCCTAG

Upstream 100 bases:

>100_bases
TTCGCGCAGGCTCCGGTAACGGACCCATCAGACTTATGCTCCTTGCGCCCCCAACTTCGGTTCGGGGGCTTTTTGTTGTC
CCCTGCCGGAAGCTCGCACC

Downstream 100 bases:

>100_bases
CGCTTTCCCCGGACCCCCAAACCTGCCATTATTGAGAAAATCGACCACAAGATAGAGCAGACCCATGGCAGATGACCTCC
TCTCCGGCGCGCCTGATGAC

Product: major facilitator transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MIATPAKTPPRLVTLILLAALSTMTLNMILPSLAAIARTFEAEYAVASLAIGGYLAVTAVVQLVVGPLSDRIGRRPVLLG
GLVIFILASVLCMVAQNIWVFLAARMAQSAMSMGYAISLAVVRDTTEPRRAASVIGTIGTIMAIAPILGPVLGGVLDTYL
GWRASFVVYALAGLAMLAWCWVDLGETRPERADARPSAVSAARTLLRLPAFRAYLACTALSTGGFFAFLAGVPFVATETF
GITTARLGFFIGSITAGYMAGSFISSRLASGLALSTMMLAGRIVACTGLTCGLIALAFGIVTPLTFFGSTICVGMGNGLT
MPSSNAGAMSVRPELAGSAAGFTGAATVACGAILTSVAGIIVPGPHAPATVLALMLAASLAALVAALAARRHETTP

Sequences:

>Translated_396_residues
MIATPAKTPPRLVTLILLAALSTMTLNMILPSLAAIARTFEAEYAVASLAIGGYLAVTAVVQLVVGPLSDRIGRRPVLLG
GLVIFILASVLCMVAQNIWVFLAARMAQSAMSMGYAISLAVVRDTTEPRRAASVIGTIGTIMAIAPILGPVLGGVLDTYL
GWRASFVVYALAGLAMLAWCWVDLGETRPERADARPSAVSAARTLLRLPAFRAYLACTALSTGGFFAFLAGVPFVATETF
GITTARLGFFIGSITAGYMAGSFISSRLASGLALSTMMLAGRIVACTGLTCGLIALAFGIVTPLTFFGSTICVGMGNGLT
MPSSNAGAMSVRPELAGSAAGFTGAATVACGAILTSVAGIIVPGPHAPATVLALMLAASLAALVAALAARRHETTP
>Mature_396_residues
MIATPAKTPPRLVTLILLAALSTMTLNMILPSLAAIARTFEAEYAVASLAIGGYLAVTAVVQLVVGPLSDRIGRRPVLLG
GLVIFILASVLCMVAQNIWVFLAARMAQSAMSMGYAISLAVVRDTTEPRRAASVIGTIGTIMAIAPILGPVLGGVLDTYL
GWRASFVVYALAGLAMLAWCWVDLGETRPERADARPSAVSAARTLLRLPAFRAYLACTALSTGGFFAFLAGVPFVATETF
GITTARLGFFIGSITAGYMAGSFISSRLASGLALSTMMLAGRIVACTGLTCGLIALAFGIVTPLTFFGSTICVGMGNGLT
MPSSNAGAMSVRPELAGSAAGFTGAATVACGAILTSVAGIIVPGPHAPATVLALMLAASLAALVAALAARRHETTP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI1790146, Length=333, Percent_Identity=32.1321321321321, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082312, Length=350, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI48994889, Length=254, Percent_Identity=30.3149606299213, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788509, Length=354, Percent_Identity=26.5536723163842, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790794, Length=239, Percent_Identity=28.8702928870293, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787065, Length=320, Percent_Identity=26.875, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87081738, Length=167, Percent_Identity=32.3353293413174, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 40389; Mature: 40389

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIATPAKTPPRLVTLILLAALSTMTLNMILPSLAAIARTFEAEYAVASLAIGGYLAVTAV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQLVVGPLSDRIGRRPVLLGGLVIFILASVLCMVAQNIWVFLAARMAQSAMSMGYAISLA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEE
VVRDTTEPRRAASVIGTIGTIMAIAPILGPVLGGVLDTYLGWRASFVVYALAGLAMLAWC
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVDLGETRPERADARPSAVSAARTLLRLPAFRAYLACTALSTGGFFAFLAGVPFVATETF
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHEECCC
GITTARLGFFIGSITAGYMAGSFISSRLASGLALSTMMLAGRIVACTGLTCGLIALAFGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTPLTFFGSTICVGMGNGLTMPSSNAGAMSVRPELAGSAAGFTGAATVACGAILTSVAGI
HHHHHHHCCHHEEECCCCCCCCCCCCCCEEECHHHCCCCCCCCHHHHHHHHHHHHHHHHE
IVPGPHAPATVLALMLAASLAALVAALAARRHETTP
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIATPAKTPPRLVTLILLAALSTMTLNMILPSLAAIARTFEAEYAVASLAIGGYLAVTAV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQLVVGPLSDRIGRRPVLLGGLVIFILASVLCMVAQNIWVFLAARMAQSAMSMGYAISLA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEE
VVRDTTEPRRAASVIGTIGTIMAIAPILGPVLGGVLDTYLGWRASFVVYALAGLAMLAWC
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVDLGETRPERADARPSAVSAARTLLRLPAFRAYLACTALSTGGFFAFLAGVPFVATETF
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHEECCC
GITTARLGFFIGSITAGYMAGSFISSRLASGLALSTMMLAGRIVACTGLTCGLIALAFGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTPLTFFGSTICVGMGNGLTMPSSNAGAMSVRPELAGSAAGFTGAATVACGAILTSVAGI
HHHHHHHCCHHEEECCCCCCCCCCCCCCEEECHHHCCCCCCCCHHHHHHHHHHHHHHHHE
IVPGPHAPATVLALMLAASLAALVAALAARRHETTP
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9202461 [H]