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The map label for this gene is acdA [H]

Identifier: 89054400

GI number: 89054400

Start: 1897865

End: 1899010

Strand: Reverse

Name: acdA [H]

Synonym: Jann_1909

Alternate gene names: 89054400

Gene position: 1899010-1897865 (Counterclockwise)

Preceding gene: 89054401

Following gene: 89054399

Centisome position: 43.98

GC content: 63.87

Gene sequence:

>1146_bases
ATGGATTTTCAGCTGAGCGAAGAGGCGCAGGCGATCTACGACATGGCGCGCGCGTTTGGAGAGGCCGAGATTGCGCCCCA
TGCCCGTGATTGGGAACGCGACGGCACAATCCCCAAGGCGCTTTGGCCGAAGCTGGCCGAATTGGGCTTTGCCGGGCTCT
ATGTGTCCGAGGAAAACGGAGGCTCAGGTCTGTCGCGGCTGGAGGCGACGCTGGTGTTTGAAGCGCTGTCGGAGGCCTGT
GCGTCGGTCGCCGCCTTCCTGTCGATCCACAATATGTGCGCGAAGATGATTGAGACCTTCGGCTCCGACGAGATGCGCGC
GACGTTTCTGCCCCGCGCGTTGTCGATGGAAACCGTGTTCTCCTACTGCCTGACGGAGCCGGGATCCGGCTCGGACGCGG
CGGCGTTGAAGACGCGGGCGGAGCGCACGAACGAAGGCTATGCGCTGACCGGCACCAAGGCGTTCATCTCGGGCGGTGGC
TATTCGGACGCCTATATCGTGATGTGCCGCACCGGAGAGGACGGGCCGCGTGGGATCTCGGCCGTGGTCGTGGAAGACGG
CGCGGATGGCCTGTCGTTCGGCGGGCTGGAGGACAAGATGGGATGGCGGTCGCAACCCACCCGCGCGGTTCAATTGGACG
ACTGTGCGGTCCCGGCGGCGAACCTTTTGGGCGAAGAAGGCCACGGGTTCCGCTATGCCATGGCGGGGTTGGATGGGGGG
CGGTTGAACATTGCGGCTTGTTCTTTGGGTGCGGCGGCGGCGGCCTTGCGGGGGACTTTGGCCTACATGGGCGAGCGGCA
GGCGTTCGGGCAGTCGATCGACCAGTTCCAGGCATTGCAGTTCCGGCTGGCGGACATGGAGATCGAGTTGGAGGCGGCGA
AGATCTTCCTGCGACAGGCCGCCTGGAAACTCGACACCGGCGCGTCGGATGCGACCAAGGCCTGCGCCATGGCCAAGAAG
TTCTGTACCGAGGCCGGGTCACGGATTGCCGATCAATGCCTGCAACTCCACGGCGGCTATGGCTATCTGGCGGATTACGG
GATCGAGAAGATCGTGCGCGACTTGCGGGTACATCAGATCCTGGAAGGCACCAATGAAATCATGCGGATGATCGTGTCGC
GGCAGATGCTGGCGGATCGCGGGTGA

Upstream 100 bases:

>100_bases
TGGCGCGGCGGCGGGTGTGAGCTTGCAATACTCCTGCAACACTCGTTAATTAAACGTACGTTCAATTAACGCGGGCCTAA
GCAATGTCGGGGAGGCAGCC

Downstream 100 bases:

>100_bases
GGTCTGTGCGCGGGGCTGGCTGCGGGATTGAGTTGTATTTGCCAAGATGAAGGAGGGGAGCGGGAATGGACGTCGAGATC
CGAATTGAAGGGCGCGCGGG

Product: butyryl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MDFQLSEEAQAIYDMARAFGEAEIAPHARDWERDGTIPKALWPKLAELGFAGLYVSEENGGSGLSRLEATLVFEALSEAC
ASVAAFLSIHNMCAKMIETFGSDEMRATFLPRALSMETVFSYCLTEPGSGSDAAALKTRAERTNEGYALTGTKAFISGGG
YSDAYIVMCRTGEDGPRGISAVVVEDGADGLSFGGLEDKMGWRSQPTRAVQLDDCAVPAANLLGEEGHGFRYAMAGLDGG
RLNIAACSLGAAAAALRGTLAYMGERQAFGQSIDQFQALQFRLADMEIELEAAKIFLRQAAWKLDTGASDATKACAMAKK
FCTEAGSRIADQCLQLHGGYGYLADYGIEKIVRDLRVHQILEGTNEIMRMIVSRQMLADRG

Sequences:

>Translated_381_residues
MDFQLSEEAQAIYDMARAFGEAEIAPHARDWERDGTIPKALWPKLAELGFAGLYVSEENGGSGLSRLEATLVFEALSEAC
ASVAAFLSIHNMCAKMIETFGSDEMRATFLPRALSMETVFSYCLTEPGSGSDAAALKTRAERTNEGYALTGTKAFISGGG
YSDAYIVMCRTGEDGPRGISAVVVEDGADGLSFGGLEDKMGWRSQPTRAVQLDDCAVPAANLLGEEGHGFRYAMAGLDGG
RLNIAACSLGAAAAALRGTLAYMGERQAFGQSIDQFQALQFRLADMEIELEAAKIFLRQAAWKLDTGASDATKACAMAKK
FCTEAGSRIADQCLQLHGGYGYLADYGIEKIVRDLRVHQILEGTNEIMRMIVSRQMLADRG
>Mature_381_residues
MDFQLSEEAQAIYDMARAFGEAEIAPHARDWERDGTIPKALWPKLAELGFAGLYVSEENGGSGLSRLEATLVFEALSEAC
ASVAAFLSIHNMCAKMIETFGSDEMRATFLPRALSMETVFSYCLTEPGSGSDAAALKTRAERTNEGYALTGTKAFISGGG
YSDAYIVMCRTGEDGPRGISAVVVEDGADGLSFGGLEDKMGWRSQPTRAVQLDDCAVPAANLLGEEGHGFRYAMAGLDGG
RLNIAACSLGAAAAALRGTLAYMGERQAFGQSIDQFQALQFRLADMEIELEAAKIFLRQAAWKLDTGASDATKACAMAKK
FCTEAGSRIADQCLQLHGGYGYLADYGIEKIVRDLRVHQILEGTNEIMRMIVSRQMLADRG

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=52.2666666666667, Blast_Score=404, Evalue=1e-112,
Organism=Homo sapiens, GI4501859, Length=377, Percent_Identity=35.0132625994695, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=32.7176781002639, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=32.7176781002639, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI4501857, Length=380, Percent_Identity=33.6842105263158, Blast_Score=225, Evalue=6e-59,
Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=35.9042553191489, Blast_Score=224, Evalue=8e-59,
Organism=Homo sapiens, GI226958412, Length=381, Percent_Identity=33.8582677165354, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI76496475, Length=358, Percent_Identity=36.3128491620112, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI4557235, Length=358, Percent_Identity=36.3128491620112, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI226958414, Length=343, Percent_Identity=34.9854227405248, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI21361497, Length=379, Percent_Identity=33.7730870712401, Blast_Score=191, Evalue=8e-49,
Organism=Homo sapiens, GI4503943, Length=378, Percent_Identity=26.984126984127, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI7669494, Length=359, Percent_Identity=26.7409470752089, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI38505218, Length=337, Percent_Identity=25.5192878338279, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI48976061, Length=343, Percent_Identity=24.7813411078717, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI211971008, Length=343, Percent_Identity=24.7813411078717, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87081958, Length=383, Percent_Identity=30.8093994778068, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1786223, Length=385, Percent_Identity=28.3116883116883, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI87082384, Length=287, Percent_Identity=29.2682926829268, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=44.1489361702128, Blast_Score=359, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17534899, Length=384, Percent_Identity=33.59375, Blast_Score=238, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=32.8083989501312, Blast_Score=232, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=33.6021505376344, Blast_Score=218, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17508101, Length=373, Percent_Identity=31.6353887399464, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI17570075, Length=382, Percent_Identity=31.9371727748691, Blast_Score=214, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=32.5396825396825, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI71985184, Length=345, Percent_Identity=31.8840579710145, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71990804, Length=283, Percent_Identity=35.3356890459364, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=32.4468085106383, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=37.3913043478261, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17551932, Length=359, Percent_Identity=30.6406685236769, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=30.9090909090909, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71985192, Length=291, Percent_Identity=31.6151202749141, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17534353, Length=375, Percent_Identity=25.8666666666667, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17531909, Length=240, Percent_Identity=27.0833333333333, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562446, Length=370, Percent_Identity=25.4054054054054, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17531913, Length=171, Percent_Identity=28.6549707602339, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI86563381, Length=275, Percent_Identity=28, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI86563383, Length=275, Percent_Identity=28, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21356377, Length=377, Percent_Identity=36.0742705570292, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=34.3915343915344, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=35.978835978836, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24666513, Length=381, Percent_Identity=33.5958005249344, Blast_Score=214, Evalue=9e-56,
Organism=Drosophila melanogaster, GI21355753, Length=380, Percent_Identity=33.9473684210526, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI281363737, Length=349, Percent_Identity=30.945558739255, Blast_Score=185, Evalue=5e-47,
Organism=Drosophila melanogaster, GI19920834, Length=381, Percent_Identity=27.5590551181102, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 40938; Mature: 40938

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFQLSEEAQAIYDMARAFGEAEIAPHARDWERDGTIPKALWPKLAELGFAGLYVSEENG
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCC
GSGLSRLEATLVFEALSEACASVAAFLSIHNMCAKMIETFGSDEMRATFLPRALSMETVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHH
SYCLTEPGSGSDAAALKTRAERTNEGYALTGTKAFISGGGYSDAYIVMCRTGEDGPRGIS
HHHHCCCCCCCCHHHHHHHHHHCCCCEEEECCHHEECCCCCCCEEEEEEECCCCCCCCEE
AVVVEDGADGLSFGGLEDKMGWRSQPTRAVQLDDCAVPAANLLGEEGHGFRYAMAGLDGG
EEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHCCCCCCCEEEEEECCCCC
RLNIAACSLGAAAAALRGTLAYMGERQAFGQSIDQFQALQFRLADMEIELEAAKIFLRQA
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHH
AWKLDTGASDATKACAMAKKFCTEAGSRIADQCLQLHGGYGYLADYGIEKIVRDLRVHQI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LEGTNEIMRMIVSRQMLADRG
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFQLSEEAQAIYDMARAFGEAEIAPHARDWERDGTIPKALWPKLAELGFAGLYVSEENG
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCC
GSGLSRLEATLVFEALSEACASVAAFLSIHNMCAKMIETFGSDEMRATFLPRALSMETVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHH
SYCLTEPGSGSDAAALKTRAERTNEGYALTGTKAFISGGGYSDAYIVMCRTGEDGPRGIS
HHHHCCCCCCCCHHHHHHHHHHCCCCEEEECCHHEECCCCCCCEEEEEEECCCCCCCCEE
AVVVEDGADGLSFGGLEDKMGWRSQPTRAVQLDDCAVPAANLLGEEGHGFRYAMAGLDGG
EEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHCCCCCCCEEEEEECCCCC
RLNIAACSLGAAAAALRGTLAYMGERQAFGQSIDQFQALQFRLADMEIELEAAKIFLRQA
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHH
AWKLDTGASDATKACAMAKKFCTEAGSRIADQCLQLHGGYGYLADYGIEKIVRDLRVHQI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LEGTNEIMRMIVSRQMLADRG
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]