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The map label for this gene is ppiD [H]

Identifier: 89054374

GI number: 89054374

Start: 1872773

End: 1874626

Strand: Reverse

Name: ppiD [H]

Synonym: Jann_1883

Alternate gene names: 89054374

Gene position: 1874626-1872773 (Counterclockwise)

Preceding gene: 89054375

Following gene: 89054373

Centisome position: 43.41

GC content: 63.54

Gene sequence:

>1854_bases
ATGGCGAAATCTGCCGCGAAAAAAGTCTCCAACGTCTTTGTCTGGATCCTGATGGGCCTGTTATTCGTCGCACTCGCGGG
CTTCGGCATCGGCTCTTTCAGCGGCGGCGCGAGCCAGGTCGGCTCCGTCGGTGATGTGGAGATCACGGCGGATGACTACT
TTCGCGCGCTCAACAACGAGATCAACGCCCAAAGCGCCGATGAACGCCGCGCCGTCCCATTTGCCGAAATCCGCGCGCGC
GGGATCGACGCACAGATCCTTGCAGGCCTGACCGCACGCGCCGCATTGAGCCATGAGGCCGGCGCCATGGGCATCTCCGT
GGGCGATGCGGAGGTCGCGGCCCAGATTGCGCAGGTCCAGGCCTTCCAGAACACGTCCGGCAATTTTGACCGCAACACGT
ATGAATTTGTCCTTCAACAACAGGGCGCTACCCCGCGGGAGTTTGAAGAAGACACGCGCGAAGATGTGGCGCGCGCGCTG
TTGCAGACCGCCGTCATCGGCGGCCTTACCCCCAATGAGATCTTTGCCGAAACTATCACCGCTTACCAATCCGAGACCCG
CGATTTCACCCGGCTGGAAGTGCGCGAAGGCGATCTGACCGTCCCTATCGCGGAGCCCACGGACGCGGAGCTTGCCGCCT
ATTACGACGAATTCCCCGAGCGGTTCACCCGCCCCGAAGCGCGCCGCATCACCTACGCCTGGATCATCCCGTCGGCGATC
ATGGACGACGTGGAGATTGATGAGGACGCCCTGCGGGAGCTGTATGATGACCGCATCGACGAATATGTTCAGCCCGAGCG
GCGGCTTCTGGAACGGCTGGTGTTCAACTCTGACGCAGAGGTCGACGCGGCCCTTGCAGCGATTGAGGCAGAGGAGACGG
ATTTCGACACGCTTGTCGCGGACCGCGACCTGACCCTTGAGGATGTGGATCTGGGCGAAATTGCCGCCGATGATCTGAGC
GATGCCGCCGCCGCCATCATTTTCGCCGATGAGGATAGCGAGCTTCTGGGGCCCGTCCCCTCCCCCCTCGGCCCCGCGCT
CTTCCGGGTGAACGCGGTCCTGCAATCGTCGGAAGTGCCGTTCGAGGAGGCCCGCGATGACCTGAGCGCGGAACTGGCGC
AGGAAGGCGCACGCCGTCAGATCGATGACATGCGTGAAGGGATTGACGATCTGCTGGCCTCCGGCGCGACGTTGGAAGAG
CTGAGCGATGGCACCGTCATGACCCTGGGAACACTGGATTATACGCCTGCCTCCGAGGAGGGCATCGCCGCCTACGACAA
TTTCCGCGATGCGGCTGTGTCGGTGCAGGACAGTGATTTCCCTGAACTGCTGGAGCTGAGCGATGGGGGCCTTTTTGCCC
TGCGCCTGGACGAGGTCGTACCGCCGACCCTGCCGCCGCTGGACGAGATCGAAGCCGAGGTGGCCGAGGCCTGGCAAGCA
ACAGCGTTGCGCGATGCGGTGGCCGAACGGGCCTCGCAACTGGTCGCGCAACTGGCGCAAGGGGCCACGCTGGAGGATCT
GGGCGACACGGCCGAGGAACGCCTGATCCGCCGCCAGGACCTGCTGCCCGATCTGCCCGCCACCACCGTGGCCCAGGTGT
TCCAGCTGGAGGGTACGGGCGATGTCGTGATGATCCCCGGGGCCGATGCCGCCCATATCGTGCGGCTCGATACGATCAAC
TCCGGCGTGCGCGATGCGCCTGACACGTCGGTGATCCTGTCGATCATGAACCAGAGCATCGCCCAATCCATGGCCGTCGA
TATCTTTGAGGCCTATGGTCAGGCGCTGCAGGCGAATGCGGGCATCACCACCAACCAAGGCGTGATCAACGCGGTTCACG
CGTCGTTTCCTTAG

Upstream 100 bases:

>100_bases
CCCTGACCCCCAATAGCCAAAGGCGCAGCCCCCCCTTGCCCCGCCTACCCCAAATGCGTATCCCAACCGCGAACCACTCC
TCTAAAAGGGCCTGATCCCC

Downstream 100 bases:

>100_bases
GGACCTCTGATGGCACAGCTCTCTGATTTTGAGGCATTTCGCGCGGGCTGGGAGCGGGGGGAAAATCAACTTGTCCACGC
GCGGCTGGCCGCCGATCTGG

Product: putative peptidyl-prolyl cis-trans isomerse D

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 617; Mature: 616

Protein sequence:

>617_residues
MAKSAAKKVSNVFVWILMGLLFVALAGFGIGSFSGGASQVGSVGDVEITADDYFRALNNEINAQSADERRAVPFAEIRAR
GIDAQILAGLTARAALSHEAGAMGISVGDAEVAAQIAQVQAFQNTSGNFDRNTYEFVLQQQGATPREFEEDTREDVARAL
LQTAVIGGLTPNEIFAETITAYQSETRDFTRLEVREGDLTVPIAEPTDAELAAYYDEFPERFTRPEARRITYAWIIPSAI
MDDVEIDEDALRELYDDRIDEYVQPERRLLERLVFNSDAEVDAALAAIEAEETDFDTLVADRDLTLEDVDLGEIAADDLS
DAAAAIIFADEDSELLGPVPSPLGPALFRVNAVLQSSEVPFEEARDDLSAELAQEGARRQIDDMREGIDDLLASGATLEE
LSDGTVMTLGTLDYTPASEEGIAAYDNFRDAAVSVQDSDFPELLELSDGGLFALRLDEVVPPTLPPLDEIEAEVAEAWQA
TALRDAVAERASQLVAQLAQGATLEDLGDTAEERLIRRQDLLPDLPATTVAQVFQLEGTGDVVMIPGADAAHIVRLDTIN
SGVRDAPDTSVILSIMNQSIAQSMAVDIFEAYGQALQANAGITTNQGVINAVHASFP

Sequences:

>Translated_617_residues
MAKSAAKKVSNVFVWILMGLLFVALAGFGIGSFSGGASQVGSVGDVEITADDYFRALNNEINAQSADERRAVPFAEIRAR
GIDAQILAGLTARAALSHEAGAMGISVGDAEVAAQIAQVQAFQNTSGNFDRNTYEFVLQQQGATPREFEEDTREDVARAL
LQTAVIGGLTPNEIFAETITAYQSETRDFTRLEVREGDLTVPIAEPTDAELAAYYDEFPERFTRPEARRITYAWIIPSAI
MDDVEIDEDALRELYDDRIDEYVQPERRLLERLVFNSDAEVDAALAAIEAEETDFDTLVADRDLTLEDVDLGEIAADDLS
DAAAAIIFADEDSELLGPVPSPLGPALFRVNAVLQSSEVPFEEARDDLSAELAQEGARRQIDDMREGIDDLLASGATLEE
LSDGTVMTLGTLDYTPASEEGIAAYDNFRDAAVSVQDSDFPELLELSDGGLFALRLDEVVPPTLPPLDEIEAEVAEAWQA
TALRDAVAERASQLVAQLAQGATLEDLGDTAEERLIRRQDLLPDLPATTVAQVFQLEGTGDVVMIPGADAAHIVRLDTIN
SGVRDAPDTSVILSIMNQSIAQSMAVDIFEAYGQALQANAGITTNQGVINAVHASFP
>Mature_616_residues
AKSAAKKVSNVFVWILMGLLFVALAGFGIGSFSGGASQVGSVGDVEITADDYFRALNNEINAQSADERRAVPFAEIRARG
IDAQILAGLTARAALSHEAGAMGISVGDAEVAAQIAQVQAFQNTSGNFDRNTYEFVLQQQGATPREFEEDTREDVARALL
QTAVIGGLTPNEIFAETITAYQSETRDFTRLEVREGDLTVPIAEPTDAELAAYYDEFPERFTRPEARRITYAWIIPSAIM
DDVEIDEDALRELYDDRIDEYVQPERRLLERLVFNSDAEVDAALAAIEAEETDFDTLVADRDLTLEDVDLGEIAADDLSD
AAAAIIFADEDSELLGPVPSPLGPALFRVNAVLQSSEVPFEEARDDLSAELAQEGARRQIDDMREGIDDLLASGATLEEL
SDGTVMTLGTLDYTPASEEGIAAYDNFRDAAVSVQDSDFPELLELSDGGLFALRLDEVVPPTLPPLDEIEAEVAEAWQAT
ALRDAVAERASQLVAQLAQGATLEDLGDTAEERLIRRQDLLPDLPATTVAQVFQLEGTGDVVMIPGADAAHIVRLDTINS
GVRDAPDTSVILSIMNQSIAQSMAVDIFEAYGQALQANAGITTNQGVINAVHASFP

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=526, Percent_Identity=23.0038022813688, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 66497; Mature: 66366

Theoretical pI: Translated: 3.77; Mature: 3.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSAAKKVSNVFVWILMGLLFVALAGFGIGSFSGGASQVGSVGDVEITADDYFRALNNE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEECHHHHHHHHCCC
INAQSADERRAVPFAEIRARGIDAQILAGLTARAALSHEAGAMGISVGDAEVAAQIAQVQ
CCCCCCCHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHH
AFQNTSGNFDRNTYEFVLQQQGATPREFEEDTREDVARALLQTAVIGGLTPNEIFAETIT
HHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AYQSETRDFTRLEVREGDLTVPIAEPTDAELAAYYDEFPERFTRPEARRITYAWIIPSAI
HHHHHCCCCEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHEEEEEEECHHHH
MDDVEIDEDALRELYDDRIDEYVQPERRLLERLVFNSDAEVDAALAAIEAEETDFDTLVA
HCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHC
DRDLTLEDVDLGEIAADDLSDAAAAIIFADEDSELLGPVPSPLGPALFRVNAVLQSSEVP
CCCCCEECCCCHHHHHHHHCCCEEEEEEECCCCHHCCCCCCCCCHHHHHHHHHHHCCCCC
FEEARDDLSAELAQEGARRQIDDMREGIDDLLASGATLEELSDGTVMTLGTLDYTPASEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEECCCCCCCCCC
GIAAYDNFRDAAVSVQDSDFPELLELSDGGLFALRLDEVVPPTLPPLDEIEAEVAEAWQA
CCCHHHCCHHHEEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
TALRDAVAERASQLVAQLAQGATLEDLGDTAEERLIRRQDLLPDLPATTVAQVFQLEGTG
HHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
DVVMIPGADAAHIVRLDTINSGVRDAPDTSVILSIMNQSIAQSMAVDIFEAYGQALQANA
CEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GITTNQGVINAVHASFP
CCCCCCCHHHHHHCCCC
>Mature Secondary Structure 
AKSAAKKVSNVFVWILMGLLFVALAGFGIGSFSGGASQVGSVGDVEITADDYFRALNNE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEECHHHHHHHHCCC
INAQSADERRAVPFAEIRARGIDAQILAGLTARAALSHEAGAMGISVGDAEVAAQIAQVQ
CCCCCCCHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHH
AFQNTSGNFDRNTYEFVLQQQGATPREFEEDTREDVARALLQTAVIGGLTPNEIFAETIT
HHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AYQSETRDFTRLEVREGDLTVPIAEPTDAELAAYYDEFPERFTRPEARRITYAWIIPSAI
HHHHHCCCCEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHEEEEEEECHHHH
MDDVEIDEDALRELYDDRIDEYVQPERRLLERLVFNSDAEVDAALAAIEAEETDFDTLVA
HCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHC
DRDLTLEDVDLGEIAADDLSDAAAAIIFADEDSELLGPVPSPLGPALFRVNAVLQSSEVP
CCCCCEECCCCHHHHHHHHCCCEEEEEEECCCCHHCCCCCCCCCHHHHHHHHHHHCCCCC
FEEARDDLSAELAQEGARRQIDDMREGIDDLLASGATLEELSDGTVMTLGTLDYTPASEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEECCCCCCCCCC
GIAAYDNFRDAAVSVQDSDFPELLELSDGGLFALRLDEVVPPTLPPLDEIEAEVAEAWQA
CCCHHHCCHHHEEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
TALRDAVAERASQLVAQLAQGATLEDLGDTAEERLIRRQDLLPDLPATTVAQVFQLEGTG
HHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
DVVMIPGADAAHIVRLDTINSGVRDAPDTSVILSIMNQSIAQSMAVDIFEAYGQALQANA
CEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GITTNQGVINAVHASFP
CCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]