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The map label for this gene is trpD

Identifier: 89054370

GI number: 89054370

Start: 1867440

End: 1868477

Strand: Reverse

Name: trpD

Synonym: Jann_1879

Alternate gene names: 89054370

Gene position: 1868477-1867440 (Counterclockwise)

Preceding gene: 89054371

Following gene: 89054369

Centisome position: 43.27

GC content: 66.57

Gene sequence:

>1038_bases
ATGACTGATGCCCCCCTGTCCGAAGCGATGAAGCCGATCATCTTTTCCGCCTCCGAAGGCCCGCTGTCGCGCGCTCAGGC
CGAAGAGGCGTTCAACCTGATGTTTGAGGGTTTAGCCTCCCCGGCGCAGATGGGCGGTCTGATCATGGCGATCCGCGCGC
GCGGCGAGTCGGTGGCCGAATACGCCGCCGCAGCCCAGGTCATGCGCGACAGATGCGTGAAGGTGAGCGCGCCCGACGGC
GCGATGGATATCGTGGGCACCGGCGGCGACGGCATGGGGACACTGAACATCTCCACCGCCACGGCCTTTGTGGTGGCGGG
CGCGGGCGTGCCGGTGGCCAAACACGGCAACCGCAACCTGTCGTCCAAATCCGGCGCGGCAGATGTGCTGACCCAGATGG
GCATCAACGTGATGGTCGGTGCAGCGGTTGTGGAACAGTCGCTCAAGGAAGCGGGCATCGGCTTCATGATGGCCCCCATG
CATCACCCGGCGGTCAAACACGTGATGCCGATCCGGCAGGAGCTTGGCTGCAAGACGATCTTCAACATTCTGGGGCCGCT
GACCAACCCCGCAGGCGCGAAACGCCAGCTGACGGGCGCCTTTGCCATCGACCTGATCTATCCCATGGCCGAGACGCTGA
AGGAGTTGGGGTCCGAGGCCGCCTGGCTGGTCCACGGCTCCGACGGCACGGACGAGATCTCGATCTCCGGCAAGACGGAT
GTGGTAGAGTTGAAGGACGGTGCCCTGCGGTCCCGCGTGGTGCATCCCGAAGATGCGGGTCTGCCCGTCCACCCGTTCCG
CGACATCCTTGGCGGCACGCCGGACGAGAATGCGCAGGCGTTCCGCGACCTGCTGGATGGTGCTCAGGGGGCCTACCGCG
ATGCGGTTCTGTTGAACGCGGCGGCGGCGCTGATCGTGGCGGGGCGCGTGACAGAACTGCGCGACGGCGTGGAGATCGCG
CGGGAGTCCATCGACAGCGGGGCGGCGAAACGGGCGGTGGAGGCCGTGGCCCGCGTGACCTCTACCTCTACCGCGTGA

Upstream 100 bases:

>100_bases
CGATCGAGGGCGTGCAATTCCACCCCGAAAGCATCCGGTCCGAGCATGGCCACGCGATGTTAAGAAATTTCCTGAATAAG
ACCGACGAGAAAGTGCCCGC

Downstream 100 bases:

>100_bases
GGCGGGTCTGGCTCCAAAAGATGAGTTGTATTGGCCCAGATGAAGGAGAAGCGGTGCGCCTGTGCCCTCACCCAGGACGC
CCGGGCGCATCGGAGCATTC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTDAPLSEAMKPIIFSASEGPLSRAQAEEAFNLMFEGLASPAQMGGLIMAIRARGESVAEYAAAAQVMRDRCVKVSAPDG
AMDIVGTGGDGMGTLNISTATAFVVAGAGVPVAKHGNRNLSSKSGAADVLTQMGINVMVGAAVVEQSLKEAGIGFMMAPM
HHPAVKHVMPIRQELGCKTIFNILGPLTNPAGAKRQLTGAFAIDLIYPMAETLKELGSEAAWLVHGSDGTDEISISGKTD
VVELKDGALRSRVVHPEDAGLPVHPFRDILGGTPDENAQAFRDLLDGAQGAYRDAVLLNAAAALIVAGRVTELRDGVEIA
RESIDSGAAKRAVEAVARVTSTSTA

Sequences:

>Translated_345_residues
MTDAPLSEAMKPIIFSASEGPLSRAQAEEAFNLMFEGLASPAQMGGLIMAIRARGESVAEYAAAAQVMRDRCVKVSAPDG
AMDIVGTGGDGMGTLNISTATAFVVAGAGVPVAKHGNRNLSSKSGAADVLTQMGINVMVGAAVVEQSLKEAGIGFMMAPM
HHPAVKHVMPIRQELGCKTIFNILGPLTNPAGAKRQLTGAFAIDLIYPMAETLKELGSEAAWLVHGSDGTDEISISGKTD
VVELKDGALRSRVVHPEDAGLPVHPFRDILGGTPDENAQAFRDLLDGAQGAYRDAVLLNAAAALIVAGRVTELRDGVEIA
RESIDSGAAKRAVEAVARVTSTSTA
>Mature_344_residues
TDAPLSEAMKPIIFSASEGPLSRAQAEEAFNLMFEGLASPAQMGGLIMAIRARGESVAEYAAAAQVMRDRCVKVSAPDGA
MDIVGTGGDGMGTLNISTATAFVVAGAGVPVAKHGNRNLSSKSGAADVLTQMGINVMVGAAVVEQSLKEAGIGFMMAPMH
HPAVKHVMPIRQELGCKTIFNILGPLTNPAGAKRQLTGAFAIDLIYPMAETLKELGSEAAWLVHGSDGTDEISISGKTDV
VELKDGALRSRVVHPEDAGLPVHPFRDILGGTPDENAQAFRDLLDGAQGAYRDAVLLNAAAALIVAGRVTELRDGVEIAR
ESIDSGAAKRAVEAVARVTSTSTA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=333, Percent_Identity=38.4384384384384, Blast_Score=205, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6320561, Length=331, Percent_Identity=31.1178247734139, Blast_Score=134, Evalue=3e-32,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_JANSC (Q28R66)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_509821.1
- HSSP:   P50384
- ProteinModelPortal:   Q28R66
- SMR:   Q28R66
- STRING:   Q28R66
- GeneID:   3934330
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_1879
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   Q28R66
- ProtClustDB:   PRK00188
- BioCyc:   JSP290400:JANN_1879-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35725; Mature: 35594

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAPLSEAMKPIIFSASEGPLSRAQAEEAFNLMFEGLASPAQMGGLIMAIRARGESVAE
CCCCCHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCCHHHHH
YAAAAQVMRDRCVKVSAPDGAMDIVGTGGDGMGTLNISTATAFVVAGAGVPVAKHGNRNL
HHHHHHHHHHHCEEEECCCCCEEEEECCCCCCEEEEEHHHHEEEEECCCCCEECCCCCCC
SSKSGAADVLTQMGINVMVGAAVVEQSLKEAGIGFMMAPMHHPAVKHVMPIRQELGCKTI
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCHHHH
FNILGPLTNPAGAKRQLTGAFAIDLIYPMAETLKELGSEAAWLVHGSDGTDEISISGKTD
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCC
VVELKDGALRSRVVHPEDAGLPVHPFRDILGGTPDENAQAFRDLLDGAQGAYRDAVLLNA
EEEECCCHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
AAALIVAGRVTELRDGVEIARESIDSGAAKRAVEAVARVTSTSTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDAPLSEAMKPIIFSASEGPLSRAQAEEAFNLMFEGLASPAQMGGLIMAIRARGESVAE
CCCCHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCCHHHHH
YAAAAQVMRDRCVKVSAPDGAMDIVGTGGDGMGTLNISTATAFVVAGAGVPVAKHGNRNL
HHHHHHHHHHHCEEEECCCCCEEEEECCCCCCEEEEEHHHHEEEEECCCCCEECCCCCCC
SSKSGAADVLTQMGINVMVGAAVVEQSLKEAGIGFMMAPMHHPAVKHVMPIRQELGCKTI
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCHHHH
FNILGPLTNPAGAKRQLTGAFAIDLIYPMAETLKELGSEAAWLVHGSDGTDEISISGKTD
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCC
VVELKDGALRSRVVHPEDAGLPVHPFRDILGGTPDENAQAFRDLLDGAQGAYRDAVLLNA
EEEECCCHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
AAALIVAGRVTELRDGVEIARESIDSGAAKRAVEAVARVTSTSTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA