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The map label for this gene is pdxA

Identifier: 89054301

GI number: 89054301

Start: 1798449

End: 1799432

Strand: Reverse

Name: pdxA

Synonym: Jann_1810

Alternate gene names: 89054301

Gene position: 1799432-1798449 (Counterclockwise)

Preceding gene: 89054302

Following gene: 89054300

Centisome position: 41.67

GC content: 66.26

Gene sequence:

>984_bases
ATGGCGGCCCTGCCCATTGCGCTCTCCGTCGGTGAGCCCGCGGGCATTGGCCCCGAGATTGCCGCCCGCGCCTGGGCCGC
ATTGGGTGCGGAGATCCCGTTCTTCGTGATCGGCGACCCGGCGCATCTGGCAGGCCATGGCGCGCCTCTGGTTAAGGTGG
CCAAGGCATCCGAAGCCGTTGCTGCCTGCCGCGACGGCCTGCCCGTTTTGCCCCATAGCTTCGCCGAACCTGCAGTTCCC
GGCCGACCCGATCCGGCCAACGCCCAGGGCGTGATCGACGTGATCGCGCGCGGCGTGGATCTGGTGATGCGGGGGGAGGC
TGCGGCGCTCACCACCGGGCCGATCCACAAGAAGGCGCTGAAGGACGGCGCGGGCTTCGCCTTCCCGGGCCACACCGAAT
ATCTGGCGCATCTGGCTGGGGTAAGGCAGGTGGTGATGATGCTCGCCTGCCCGGAGCTGCGTGTGGTGCCGGTGACGATC
CACATCCCCGTCGCGGAGGTGCCCCGTTTGCTGACCGCAAAGTTGCTCCGCGATACCATTCGCATCACCGAGGCCGCGTT
GCGGCAGGATTTCGGGATCGCGAGGCCTCGGATCGCGGTCGCGGGCCTCAACCCCCATGCAGGCGAAGGTGGGGCCATGG
GCCGTGAGGAAATCGAGTTGATTACACCGGTGCTGGACGAATTGCGGGCCAATGGACTGACCATCAACGGGCCTGCCTCT
GCCGATACAATGTTCCACGCAAGCGCTCGGGCGGGTTATGACGTTGCAATCGCGATGTACCACGATCAGGCCCTGATCCC
GATCAAGACGGTGGATTTCTCGGGCGGGGTGAACGTGACCCTCGGCCTGCCATTCATCCGCACGTCACCGGACCACGGCA
CGGCGTTTGATATCGCGGGCCAGGGCATCGCCGATGCGACATCGCTGATTGCCGCGTTGAAAATGGCGCGCGATATGGCT
GTGGCGCGGGGCGAGACCCGATGA

Upstream 100 bases:

>100_bases
CCGGATCCGCGAACAGCTATTCGGTCAGCAATTGCAGCGTCTGGCGGCGAACTATCTGGAAGAGCTGCGCGCTGAGGCCC
GCATCAATTACGTCAACTGA

Downstream 100 bases:

>100_bases
GCCTGCGTCCTTGGCCGATGGCGTTGCGGGGCTGTCTGCCCCCCTGGAGCATCGAAGATGCCCCATCCCCCCGAGAGGTG
TATGGCCAAGATGAAGGAGC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MAALPIALSVGEPAGIGPEIAARAWAALGAEIPFFVIGDPAHLAGHGAPLVKVAKASEAVAACRDGLPVLPHSFAEPAVP
GRPDPANAQGVIDVIARGVDLVMRGEAAALTTGPIHKKALKDGAGFAFPGHTEYLAHLAGVRQVVMMLACPELRVVPVTI
HIPVAEVPRLLTAKLLRDTIRITEAALRQDFGIARPRIAVAGLNPHAGEGGAMGREEIELITPVLDELRANGLTINGPAS
ADTMFHASARAGYDVAIAMYHDQALIPIKTVDFSGGVNVTLGLPFIRTSPDHGTAFDIAGQGIADATSLIAALKMARDMA
VARGETR

Sequences:

>Translated_327_residues
MAALPIALSVGEPAGIGPEIAARAWAALGAEIPFFVIGDPAHLAGHGAPLVKVAKASEAVAACRDGLPVLPHSFAEPAVP
GRPDPANAQGVIDVIARGVDLVMRGEAAALTTGPIHKKALKDGAGFAFPGHTEYLAHLAGVRQVVMMLACPELRVVPVTI
HIPVAEVPRLLTAKLLRDTIRITEAALRQDFGIARPRIAVAGLNPHAGEGGAMGREEIELITPVLDELRANGLTINGPAS
ADTMFHASARAGYDVAIAMYHDQALIPIKTVDFSGGVNVTLGLPFIRTSPDHGTAFDIAGQGIADATSLIAALKMARDMA
VARGETR
>Mature_326_residues
AALPIALSVGEPAGIGPEIAARAWAALGAEIPFFVIGDPAHLAGHGAPLVKVAKASEAVAACRDGLPVLPHSFAEPAVPG
RPDPANAQGVIDVIARGVDLVMRGEAAALTTGPIHKKALKDGAGFAFPGHTEYLAHLAGVRQVVMMLACPELRVVPVTIH
IPVAEVPRLLTAKLLRDTIRITEAALRQDFGIARPRIAVAGLNPHAGEGGAMGREEIELITPVLDELRANGLTINGPASA
DTMFHASARAGYDVAIAMYHDQALIPIKTVDFSGGVNVTLGLPFIRTSPDHGTAFDIAGQGIADATSLIAALKMARDMAV
ARGETR

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=326, Percent_Identity=44.7852760736196, Blast_Score=248, Evalue=5e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001804
- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 33838; Mature: 33706

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALPIALSVGEPAGIGPEIAARAWAALGAEIPFFVIGDPAHLAGHGAPLVKVAKASEAV
CCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHCCCCCCCEEEHHHHHHH
AACRDGLPVLPHSFAEPAVPGRPDPANAQGVIDVIARGVDLVMRGEAAALTTGPIHKKAL
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCEEECCCHHHHHH
KDGAGFAFPGHTEYLAHLAGVRQVVMMLACPELRVVPVTIHIPVAEVPRLLTAKLLRDTI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHH
RITEAALRQDFGIARPRIAVAGLNPHAGEGGAMGREEIELITPVLDELRANGLTINGPAS
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCC
ADTMFHASARAGYDVAIAMYHDQALIPIKTVDFSGGVNVTLGLPFIRTSPDHGTAFDIAG
CCCEEEECCCCCCEEEEEEECCCEEEEEEEEECCCCCEEEEECCEEEECCCCCCEEEECC
QGIADATSLIAALKMARDMAVARGETR
CCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AALPIALSVGEPAGIGPEIAARAWAALGAEIPFFVIGDPAHLAGHGAPLVKVAKASEAV
CCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHCCCCCCCEEEHHHHHHH
AACRDGLPVLPHSFAEPAVPGRPDPANAQGVIDVIARGVDLVMRGEAAALTTGPIHKKAL
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCEEECCCHHHHHH
KDGAGFAFPGHTEYLAHLAGVRQVVMMLACPELRVVPVTIHIPVAEVPRLLTAKLLRDTI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHH
RITEAALRQDFGIARPRIAVAGLNPHAGEGGAMGREEIELITPVLDELRANGLTINGPAS
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCC
ADTMFHASARAGYDVAIAMYHDQALIPIKTVDFSGGVNVTLGLPFIRTSPDHGTAFDIAG
CCCEEEECCCCCCEEEEEEECCCEEEEEEEEECCCCCEEEEECCEEEECCCCCCEEEECC
QGIADATSLIAALKMARDMAVARGETR
CCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA