Click here to switch to the map view.

The map label for this gene is alr

Identifier: 89054230

GI number: 89054230

Start: 1731022

End: 1732050

Strand: Reverse

Name: alr

Synonym: Jann_1739

Alternate gene names: 89054230

Gene position: 1732050-1731022 (Counterclockwise)

Preceding gene: 89054231

Following gene: 89054229

Centisome position: 40.11

GC content: 66.18

Gene sequence:

>1029_bases
ATGGCCACCGGAACTCTCACCGTCGATCTCGGCGCACTTGTCGCCAATTACCGCACCCTGGACCGGCTTGGTCCCGGCGC
AACGGCGGCTGTTGTCAAAGCCGACGGCTACGGGCTCGGGGCAGGGCTGGTCAGCACCGGACTGGCCAAAGCTGGTGCCT
GCCAGTTTTTCGTTGCCACGGCAGAAGAGGGCGTGGGCCTGCGCCAGGTCCTTGGACCTGCGCCGGAAATCAACGTCTTC
GCAGGTCACATGGCGGGCGATACCCCGCTGATCCGCGACGCCCACCTCACCCCCATGCTGAATTCGCCCAAGCAGGTTCA
GCGCCATCGCCATGTCCTGCCCGGCCACCCCTACGGCATCCAGCTCGACACCGGCATGCACCGCCTCGGCGTACAGCCCG
CCGATTGGCCCGCCCTGCGCGATCAGCTCCACGATGCCACGCTTCTGATGTCCCATCTTGCCTGCGCCGATGCGCCGGAT
CATCCACAAAATGCCGCACAGCTGGCGCAGTTCCGTGCGCTGACCGACGGCATCCAAACGCCCCGGTCTCTGGCTGCCAC
CGGTGGCACGCTGATGGGTCCAGACTACCACTTTGACCTCATCCGCCCGGGCGTGGGCCTCTACGGCGGCCTGCCCTTCG
CGGGTGCCCGTCCGGTCGTTCGCCTGTCCCTTCCCGTCATCCAGATCCGCTGTGTCAACCCGGGCGCTACAATCGGCTAT
GGCGCCACCTACACCGCAACCACGCCCCGTCAAATTGCAACACTATCAGCCGGTTATGCCGATGGCCTCATCCGCGCCCT
GTCGTCCAAGGCCACGCTTTGGGACGGTGATACGCCCTGCCCTCTGGTCGGCCGGGTGTCCATGGATCTGCTGACCGTCG
ACGTCACGGACTGCGACACGCCACCGGAGGCGCTCGACATTCTCGGGCCCCATCAGACCATCGATCAACTGGCCGAGGCG
GCGGGCACCATCGGCTATGAAATCCTCACCTCCCTGGGCCCTCGCTACCGGCGCGCGTTAACCCCGTGA

Upstream 100 bases:

>100_bases
CCCACCGCTTTACAAAGCGGTGTCTCACGTCCTTGCAAGGACGTGCCAAGGCTCTTGCAAGAGCCTTGACGCGATCGCCG
TTAGATCGCACGAACCCGCT

Downstream 100 bases:

>100_bases
CCCTGACCGCGCCCTTCGGCGCGCTTGGCCGCGCGACCCTCATCGCCCTGGCCACCATCGGCCAGATCGCCCTGTTCGCG
CTCGATGCCCTCCGCCACCT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MATGTLTVDLGALVANYRTLDRLGPGATAAVVKADGYGLGAGLVSTGLAKAGACQFFVATAEEGVGLRQVLGPAPEINVF
AGHMAGDTPLIRDAHLTPMLNSPKQVQRHRHVLPGHPYGIQLDTGMHRLGVQPADWPALRDQLHDATLLMSHLACADAPD
HPQNAAQLAQFRALTDGIQTPRSLAATGGTLMGPDYHFDLIRPGVGLYGGLPFAGARPVVRLSLPVIQIRCVNPGATIGY
GATYTATTPRQIATLSAGYADGLIRALSSKATLWDGDTPCPLVGRVSMDLLTVDVTDCDTPPEALDILGPHQTIDQLAEA
AGTIGYEILTSLGPRYRRALTP

Sequences:

>Translated_342_residues
MATGTLTVDLGALVANYRTLDRLGPGATAAVVKADGYGLGAGLVSTGLAKAGACQFFVATAEEGVGLRQVLGPAPEINVF
AGHMAGDTPLIRDAHLTPMLNSPKQVQRHRHVLPGHPYGIQLDTGMHRLGVQPADWPALRDQLHDATLLMSHLACADAPD
HPQNAAQLAQFRALTDGIQTPRSLAATGGTLMGPDYHFDLIRPGVGLYGGLPFAGARPVVRLSLPVIQIRCVNPGATIGY
GATYTATTPRQIATLSAGYADGLIRALSSKATLWDGDTPCPLVGRVSMDLLTVDVTDCDTPPEALDILGPHQTIDQLAEA
AGTIGYEILTSLGPRYRRALTP
>Mature_341_residues
ATGTLTVDLGALVANYRTLDRLGPGATAAVVKADGYGLGAGLVSTGLAKAGACQFFVATAEEGVGLRQVLGPAPEINVFA
GHMAGDTPLIRDAHLTPMLNSPKQVQRHRHVLPGHPYGIQLDTGMHRLGVQPADWPALRDQLHDATLLMSHLACADAPDH
PQNAAQLAQFRALTDGIQTPRSLAATGGTLMGPDYHFDLIRPGVGLYGGLPFAGARPVVRLSLPVIQIRCVNPGATIGYG
ATYTATTPRQIATLSAGYADGLIRALSSKATLWDGDTPCPLVGRVSMDLLTVDVTDCDTPPEALDILGPHQTIDQLAEAA
GTIGYEILTSLGPRYRRALTP

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1790487, Length=354, Percent_Identity=31.638418079096, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1787439, Length=351, Percent_Identity=33.048433048433, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_JANSC (Q28RK6)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_509681.1
- ProteinModelPortal:   Q28RK6
- SMR:   Q28RK6
- STRING:   Q28RK6
- GeneID:   3934187
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_1739
- eggNOG:   COG0787
- HOGENOM:   HBG712172
- OMA:   YCTPDKI
- PhylomeDB:   Q28RK6
- ProtClustDB:   CLSK933932
- BioCyc:   JSP290400:JANN_1739-MONOMER
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 35809; Mature: 35678

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 33-33 ACT_SITE 240-240

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGTLTVDLGALVANYRTLDRLGPGATAAVVKADGYGLGAGLVSTGLAKAGACQFFVAT
CCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEE
AEEGVGLRQVLGPAPEINVFAGHMAGDTPLIRDAHLTPMLNSPKQVQRHRHVLPGHPYGI
CCCCCCHHHHHCCCCCCEEEEECCCCCCCCEECCCCCCCCCCHHHHHHHCCCCCCCCCCE
QLDTGMHRLGVQPADWPALRDQLHDATLLMSHLACADAPDHPQNAAQLAQFRALTDGIQT
EECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
PRSLAATGGTLMGPDYHFDLIRPGVGLYGGLPFAGARPVVRLSLPVIQIRCVNPGATIGY
CHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCEEEEEEECCCCEECC
GATYTATTPRQIATLSAGYADGLIRALSSKATLWDGDTPCPLVGRVSMDLLTVDVTDCDT
CCEEECCCCHHHHHECCCHHHHHHHHHHCCCEEECCCCCCCEECCEEEEEEEEEECCCCC
PPEALDILGPHQTIDQLAEAAGTIGYEILTSLGPRYRRALTP
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCC
>Mature Secondary Structure 
ATGTLTVDLGALVANYRTLDRLGPGATAAVVKADGYGLGAGLVSTGLAKAGACQFFVAT
CCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEE
AEEGVGLRQVLGPAPEINVFAGHMAGDTPLIRDAHLTPMLNSPKQVQRHRHVLPGHPYGI
CCCCCCHHHHHCCCCCCEEEEECCCCCCCCEECCCCCCCCCCHHHHHHHCCCCCCCCCCE
QLDTGMHRLGVQPADWPALRDQLHDATLLMSHLACADAPDHPQNAAQLAQFRALTDGIQT
EECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
PRSLAATGGTLMGPDYHFDLIRPGVGLYGGLPFAGARPVVRLSLPVIQIRCVNPGATIGY
CHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCEEEEEEECCCCEECC
GATYTATTPRQIATLSAGYADGLIRALSSKATLWDGDTPCPLVGRVSMDLLTVDVTDCDT
CCEEECCCCHHHHHECCCHHHHHHHHHHCCCEEECCCCCCCEECCEEEEEEEEEECCCCC
PPEALDILGPHQTIDQLAEAAGTIGYEILTSLGPRYRRALTP
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA