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The map label for this gene is fabG [H]

Identifier: 89053836

GI number: 89053836

Start: 1310550

End: 1311275

Strand: Direct

Name: fabG [H]

Synonym: Jann_1345

Alternate gene names: 89053836

Gene position: 1310550-1311275 (Clockwise)

Preceding gene: 89053835

Following gene: 89053837

Centisome position: 30.35

GC content: 63.77

Gene sequence:

>726_bases
ATGAGCGATCTGACAGCCGTCATTACGGGCGGGAACAAGGGGATCGGCGCCGATCTGGCGCGCGCGTTGCTCGATCGGGA
CTACACCGTCGTCTCGGTCTCCCGCCATGCGCCCGATTGGACCCATCCGCGATTGTCCTCGGTGGAGGCGGATTTGCTGA
ACGCGGAGACAGTCAAGCTCGCGGCGGACCATATCGCCGCAACCCATGACGTCAGCCATCTGATCCACAATGCAGGGATG
ATCTGGCCCAATCTGGTGGAGGAGGCGCAGCCCTCGGACATCACCGGCCTGGCACAACTGCACCTCGGCTCGGCGCTAAC
GCTGCTGCAAGCCACGCTACCCTCAATGAAAGCGCGCGGCATGGGGCGGGTCATGTTCAATGCCTCCCGTGCGGCCCTCG
GCGCGCCCACGCGCACGGCCTACAGCGCCAGCAAGGCAGGTATGATCGGCATGGCGCGCACCTGGGCGTTGGAACTTGCG
CCACATGGCATCACCGTGAACGTCGTCGCCCCCGGTCCGATCCTGACGGACAATTTCTGGGGCATCATAGACAAAGACAG
CCCCCAGCAAGAGGCGCTGGCCAAACGTATCCCGGTGGGTCGGCTTGGCACGGTCGAGGACGTCACCAACGCGTTCCTGT
TTTTCTGCGATCCGACCAATGGGTTCGTGACGGGGCAAACGCTCTATGTGTGCGGTGGGGCCAGCGTTGGGACGCTCCAG
ATCTAG

Upstream 100 bases:

>100_bases
TTCATGATTTGGCGCTCGTCGACGGCGCGTTGCGGATCGCGGGCAAAAAGGTTGTGCTGCTAAACTCGGACGCCGCGTTC
GGCAATATTCAGTTGCTGCC

Downstream 100 bases:

>100_bases
CGCGCGCATCTCGATTGGGCGCGAAGGATGTCCTGACCCAGGCCCGCATGGTACTCATTTTGGCACCAACGAGGTCAAGA
CCAGGTTGCGCCAAATGGAA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSDLTAVITGGNKGIGADLARALLDRDYTVVSVSRHAPDWTHPRLSSVEADLLNAETVKLAADHIAATHDVSHLIHNAGM
IWPNLVEEAQPSDITGLAQLHLGSALTLLQATLPSMKARGMGRVMFNASRAALGAPTRTAYSASKAGMIGMARTWALELA
PHGITVNVVAPGPILTDNFWGIIDKDSPQQEALAKRIPVGRLGTVEDVTNAFLFFCDPTNGFVTGQTLYVCGGASVGTLQ
I

Sequences:

>Translated_241_residues
MSDLTAVITGGNKGIGADLARALLDRDYTVVSVSRHAPDWTHPRLSSVEADLLNAETVKLAADHIAATHDVSHLIHNAGM
IWPNLVEEAQPSDITGLAQLHLGSALTLLQATLPSMKARGMGRVMFNASRAALGAPTRTAYSASKAGMIGMARTWALELA
PHGITVNVVAPGPILTDNFWGIIDKDSPQQEALAKRIPVGRLGTVEDVTNAFLFFCDPTNGFVTGQTLYVCGGASVGTLQ
I
>Mature_240_residues
SDLTAVITGGNKGIGADLARALLDRDYTVVSVSRHAPDWTHPRLSSVEADLLNAETVKLAADHIAATHDVSHLIHNAGMI
WPNLVEEAQPSDITGLAQLHLGSALTLLQATLPSMKARGMGRVMFNASRAALGAPTRTAYSASKAGMIGMARTWALELAP
HGITVNVVAPGPILTDNFWGIIDKDSPQQEALAKRIPVGRLGTVEDVTNAFLFFCDPTNGFVTGQTLYVCGGASVGTLQI

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=29.4354838709677, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI126723750, Length=161, Percent_Identity=35.4037267080745, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI32483357, Length=127, Percent_Identity=35.4330708661417, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI7705925, Length=237, Percent_Identity=29.1139240506329, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=27.9352226720648, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=27.5590551181102, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI66933014, Length=186, Percent_Identity=26.3440860215054, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4503301, Length=199, Percent_Identity=25.1256281407035, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=236, Percent_Identity=28.8135593220339, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1789208, Length=239, Percent_Identity=29.2887029288703, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=30, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1786812, Length=243, Percent_Identity=26.3374485596708, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=26.1044176706827, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI87082160, Length=240, Percent_Identity=27.5, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=25.0980392156863, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=27.5303643724696, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786701, Length=218, Percent_Identity=27.5229357798165, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=28.099173553719, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI2367365, Length=228, Percent_Identity=28.0701754385965, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=28.0632411067194, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=28.1124497991968, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=26.8292682926829, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=28.2786885245902, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=26.9961977186312, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=259, Percent_Identity=25.8687258687259, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=26.4822134387352, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=146, Percent_Identity=32.1917808219178, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=28.2786885245902, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=27.6422764227642, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=29.2181069958848, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=26.1410788381743, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI18859837, Length=183, Percent_Identity=26.775956284153, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25417; Mature: 25286

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLTAVITGGNKGIGADLARALLDRDYTVVSVSRHAPDWTHPRLSSVEADLLNAETVKL
CCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHH
AADHIAATHDVSHLIHNAGMIWPNLVEEAQPSDITGLAQLHLGSALTLLQATLPSMKARG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
MGRVMFNASRAALGAPTRTAYSASKAGMIGMARTWALELAPHGITVNVVAPGPILTDNFW
CEEEEEECCHHHCCCCCCHHHCCCCCCCEEEHHEEEEEECCCCEEEEEEECCCEEECCCC
GIIDKDSPQQEALAKRIPVGRLGTVEDVTNAFLFFCDPTNGFVTGQTLYVCGGASVGTLQ
EEECCCCCHHHHHHHHCCCCCCCCHHHHCCEEEEEECCCCCEEECCEEEEECCCCCEEEE
I
C
>Mature Secondary Structure 
SDLTAVITGGNKGIGADLARALLDRDYTVVSVSRHAPDWTHPRLSSVEADLLNAETVKL
CCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHH
AADHIAATHDVSHLIHNAGMIWPNLVEEAQPSDITGLAQLHLGSALTLLQATLPSMKARG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
MGRVMFNASRAALGAPTRTAYSASKAGMIGMARTWALELAPHGITVNVVAPGPILTDNFW
CEEEEEECCHHHCCCCCCHHHCCCCCCCEEEHHEEEEEECCCCEEEEEEECCCEEECCCC
GIIDKDSPQQEALAKRIPVGRLGTVEDVTNAFLFFCDPTNGFVTGQTLYVCGGASVGTLQ
EEECCCCCHHHHHHHHCCCCCCCCHHHHCCEEEEEECCCCCEEECCEEEEECCCCCEEEE
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]