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The map label for this gene is tlyC [H]

Identifier: 89053195

GI number: 89053195

Start: 675679

End: 676617

Strand: Direct

Name: tlyC [H]

Synonym: Jann_0704

Alternate gene names: 89053195

Gene position: 675679-676617 (Clockwise)

Preceding gene: 89053194

Following gene: 89053196

Centisome position: 15.65

GC content: 62.09

Gene sequence:

>939_bases
TTGGCCCGGGTGATACCTTGGAAAGGAGCCATGAGCTCAAACCCTGATCCGTCGTCTTCTGCGGCGCGTGGCGCGCCCCC
TGCAGATATTGAGACCGACGAAGAGACCCCGACCCAGAGGCCGGGATTTTTTGCCCGCATTTTCGGGACAGAGGAGCAAG
GGCCTGATCCCGAGCTTGATCCGTTCCCCGACAACGCATCGACCCCTCAAACATTCGGTCCCCGGTTGCCTGGCATCTCA
AACCTGCGGCGCATGCGGGTGGAGGATGTGGCAATCCCCCGGGCCGAAATCACCTCTGTCGCCGCCGACACGGATCTGCC
TGATCTGGTGCAGGTCTTCCGCGATAGCGGGCTGACGCGGCTGCCGGTCTATGACGGTGCGCTGGACGAACCTATCGGTC
TTGTGCACCTCAAGGACATTGCACTGCGCCATGGCTTCAACGGCGACGGAGAGGATTTTATCCTGTCCGAAAGCCTGCGC
CCGGTCCTGTATGTGCCGCCTTCGATGCCCATTGGCGTTCTGCTCACGAAGATGCAGGCCGACCGCACCCATATGGCGCT
GGTGATTGACGAATATGGCGGCGTCGACGGGCTGCTGACCATTGAGGATCTGATCGAACAGGTCATCGGTGAGATCGAGG
ATGAACACGACGTTGAAGAGGCGCAGCCCTGGGTGCGCGAGGACGACGGTGCGTTTCTTGCGCTGGCCCGTGCGCCGCTC
GACGAGTTTGAATCCGAGATCGGCATGGAGCTGGTTGATGATGAGGAAGAGGAGGAGGTCGATACCCTCGGCGGGCTTGT
CTTCCTTCTGACAGGTCGCGTGCCTGCGCGGGGCGAAGTCGTTCCCCACCCCACGGGCTTGGAGTTTGAGGTGATCGACG
CCGATCCGCGCCGCATCAAGCGGCTGCGCGTGCGTTTGCCTGCCGAGAAGGCCGGTTGA

Upstream 100 bases:

>100_bases
CCATGAAACCGATGCAGACGCGGATCTTATGGAACGCCTTGAGACGCGCATACTTGCCAGACTGGGGGTCCCTGACCCAT
ATTAGGGTCTACGGGCAATT

Downstream 100 bases:

>100_bases
AGGATCTCACGCGTTGGCAGGGCCGTGGTTTGGCCGCCCTTGGGGGCGGTGTTGCCGCGCTGTCCTTGCCACCGTTTGAT
CTTTGGGCCGTGATCTTCCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MARVIPWKGAMSSNPDPSSSAARGAPPADIETDEETPTQRPGFFARIFGTEEQGPDPELDPFPDNASTPQTFGPRLPGIS
NLRRMRVEDVAIPRAEITSVAADTDLPDLVQVFRDSGLTRLPVYDGALDEPIGLVHLKDIALRHGFNGDGEDFILSESLR
PVLYVPPSMPIGVLLTKMQADRTHMALVIDEYGGVDGLLTIEDLIEQVIGEIEDEHDVEEAQPWVREDDGAFLALARAPL
DEFESEIGMELVDDEEEEEVDTLGGLVFLLTGRVPARGEVVPHPTGLEFEVIDADPRRIKRLRVRLPAEKAG

Sequences:

>Translated_312_residues
MARVIPWKGAMSSNPDPSSSAARGAPPADIETDEETPTQRPGFFARIFGTEEQGPDPELDPFPDNASTPQTFGPRLPGIS
NLRRMRVEDVAIPRAEITSVAADTDLPDLVQVFRDSGLTRLPVYDGALDEPIGLVHLKDIALRHGFNGDGEDFILSESLR
PVLYVPPSMPIGVLLTKMQADRTHMALVIDEYGGVDGLLTIEDLIEQVIGEIEDEHDVEEAQPWVREDDGAFLALARAPL
DEFESEIGMELVDDEEEEEVDTLGGLVFLLTGRVPARGEVVPHPTGLEFEVIDADPRRIKRLRVRLPAEKAG
>Mature_311_residues
ARVIPWKGAMSSNPDPSSSAARGAPPADIETDEETPTQRPGFFARIFGTEEQGPDPELDPFPDNASTPQTFGPRLPGISN
LRRMRVEDVAIPRAEITSVAADTDLPDLVQVFRDSGLTRLPVYDGALDEPIGLVHLKDIALRHGFNGDGEDFILSESLRP
VLYVPPSMPIGVLLTKMQADRTHMALVIDEYGGVDGLLTIEDLIEQVIGEIEDEHDVEEAQPWVREDDGAFLALARAPLD
EFESEIGMELVDDEEEEEVDTLGGLVFLLTGRVPARGEVVPHPTGLEFEVIDADPRRIKRLRVRLPAEKAG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=197, Percent_Identity=26.9035532994924, Blast_Score=95, Evalue=9e-20,
Organism=Escherichia coli, GI1786879, Length=280, Percent_Identity=33.5714285714286, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI145693175, Length=232, Percent_Identity=23.7068965517241, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082033, Length=278, Percent_Identity=26.6187050359712, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 34200; Mature: 34069

Theoretical pI: Translated: 4.05; Mature: 4.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVIPWKGAMSSNPDPSSSAARGAPPADIETDEETPTQRPGFFARIFGTEEQGPDPELD
CCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
PFPDNASTPQTFGPRLPGISNLRRMRVEDVAIPRAEITSVAADTDLPDLVQVFRDSGLTR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHCCCEE
LPVYDGALDEPIGLVHLKDIALRHGFNGDGEDFILSESLRPVLYVPPSMPIGVLLTKMQA
CCCCCCCCCCCCCEEEHHHHHHHCCCCCCCCCEEECCCCCCEEEECCCCCHHHHHHHHHC
DRTHMALVIDEYGGVDGLLTIEDLIEQVIGEIEDEHDVEEAQPWVREDDGAFLALARAPL
CCCEEEEEEECCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHCCCEECCCCCEEEEECCCH
DEFESEIGMELVDDEEEEEVDTLGGLVFLLTGRVPARGEVVPHPTGLEFEVIDADPRRIK
HHHHHHCCCEECCCCCHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHH
RLRVRLPAEKAG
HHHHCCCHHCCC
>Mature Secondary Structure 
ARVIPWKGAMSSNPDPSSSAARGAPPADIETDEETPTQRPGFFARIFGTEEQGPDPELD
CEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
PFPDNASTPQTFGPRLPGISNLRRMRVEDVAIPRAEITSVAADTDLPDLVQVFRDSGLTR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHCCCEE
LPVYDGALDEPIGLVHLKDIALRHGFNGDGEDFILSESLRPVLYVPPSMPIGVLLTKMQA
CCCCCCCCCCCCCEEEHHHHHHHCCCCCCCCCEEECCCCCCEEEECCCCCHHHHHHHHHC
DRTHMALVIDEYGGVDGLLTIEDLIEQVIGEIEDEHDVEEAQPWVREDDGAFLALARAPL
CCCEEEEEEECCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHCCCEECCCCCEEEEECCCH
DEFESEIGMELVDDEEEEEVDTLGGLVFLLTGRVPARGEVVPHPTGLEFEVIDADPRRIK
HHHHHHCCCEECCCCCHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHH
RLRVRLPAEKAG
HHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA