| Definition | Ehrlichia chaffeensis str. Arkansas, complete genome. |
|---|---|
| Accession | NC_007799 |
| Length | 1,176,248 |
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The map label for this gene is topA [H]
Identifier: 88658490
GI number: 88658490
Start: 753014
End: 753796
Strand: Direct
Name: topA [H]
Synonym: ECH_0746
Alternate gene names: 88658490
Gene position: 753014-753796 (Clockwise)
Preceding gene: 88658007
Following gene: 88658100
Centisome position: 64.02
GC content: 28.86
Gene sequence:
>783_bases TTGGATTTAATCTCTAATGGGAAGATTAATTGGAAGGAAGTACTACATCAATTCTGGTTTCTGTTTATTGATAATGTTAA TTCAGTAAAAAAACTAGAATTTACTGAAGTATTAAAAGTTATTAGTTGTGAGATGGAAAATTATATTTTTTCTTCTGATA AATCTGAATCTAGTAGAGTATGTCCTGTATGTAATGATGGAACATTAGAGCTTAATATTAGTAAGAATGGTATTTTTTTA GGATGTTCTAAATATCCAGAGTGTAAGTATACAAAAAATGTTGGAAGTGGTATTGTTGATGATACAGACAATACACAATA TCCTAAAATATTAGGTATTGATGCTGCAACAGGACAAGAAATATATCTTAAAAAAGGTCCGTATGGTCTCTATTTACAGA TTGGTAATGATAAAAGTGGTAAACGTGCAGCTATTCCAAAAAATATAGATGCTAATTTATTAGATTTGCAAATGGCAGAA AAAATATTAAGTTTACCTATAAGCTTAGGTACTCATCCGGATACTGGTCAAGAAATTAAGTTAGGACTTGGTAAGTTTGG TGCATACATATTGTATGGTGGTAAGTATTTTTCAGTAAAAAATGAGCATAATTTTTTAGATATTAGCATTGAAAACGCTA TTAATATTATTGCGAATAATTCTACAAGTGGGGTTATAAAGTCTCTGGGTATCACTGAAGATAATAAAGAAGTATTCTTA ACACTAATAATGATATTACAAAAAATAGATCATGCGTTATATGATTACTTAGGGGCTAAGTAG
Upstream 100 bases:
>100_bases ACAATGGGTACCTAGTTATAACAACTACAAATAAAAATACTTCATTAATTTTTTTAGTCGCTATGTAGAATATGATTTTA CTGCTGACCTTGAAGAAAAG
Downstream 100 bases:
>100_bases TTCAGTGGCATAGTAGGAGAATCATAATTTCTCAGTCGCGGGTTCAAATCCCTCCTTAGCCACTTAATTCATTAGCATTA GAGAGTCCTTGGTATTCTAT
Product: topoisomerase DNA-binding C4 zinc finger domain-containing protein
Products: NA
Alternate protein names: DNA topoisomerase I; Omega-protein; Relaxing enzyme; Swivelase; Untwisting enzyme [H]
Number of amino acids: Translated: 260; Mature: 260
Protein sequence:
>260_residues MDLISNGKINWKEVLHQFWFLFIDNVNSVKKLEFTEVLKVISCEMENYIFSSDKSESSRVCPVCNDGTLELNISKNGIFL GCSKYPECKYTKNVGSGIVDDTDNTQYPKILGIDAATGQEIYLKKGPYGLYLQIGNDKSGKRAAIPKNIDANLLDLQMAE KILSLPISLGTHPDTGQEIKLGLGKFGAYILYGGKYFSVKNEHNFLDISIENAINIIANNSTSGVIKSLGITEDNKEVFL TLIMILQKIDHALYDYLGAK
Sequences:
>Translated_260_residues MDLISNGKINWKEVLHQFWFLFIDNVNSVKKLEFTEVLKVISCEMENYIFSSDKSESSRVCPVCNDGTLELNISKNGIFL GCSKYPECKYTKNVGSGIVDDTDNTQYPKILGIDAATGQEIYLKKGPYGLYLQIGNDKSGKRAAIPKNIDANLLDLQMAE KILSLPISLGTHPDTGQEIKLGLGKFGAYILYGGKYFSVKNEHNFLDISIENAINIIANNSTSGVIKSLGITEDNKEVFL TLIMILQKIDHALYDYLGAK >Mature_260_residues MDLISNGKINWKEVLHQFWFLFIDNVNSVKKLEFTEVLKVISCEMENYIFSSDKSESSRVCPVCNDGTLELNISKNGIFL GCSKYPECKYTKNVGSGIVDDTDNTQYPKILGIDAATGQEIYLKKGPYGLYLQIGNDKSGKRAAIPKNIDANLLDLQMAE KILSLPISLGTHPDTGQEIKLGLGKFGAYILYGGKYFSVKNEHNFLDISIENAINIIANNSTSGVIKSLGITEDNKEVFL TLIMILQKIDHALYDYLGAK
Specific function: The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another [H]
COG id: COG1754
COG function: function code R; Uncharacterized C-terminal domain of topoisomerase IA
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Toprim domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003601 - InterPro: IPR013497 - InterPro: IPR013824 - InterPro: IPR013825 - InterPro: IPR000380 - InterPro: IPR003602 - InterPro: IPR013498 - InterPro: IPR005733 - InterPro: IPR006171 [H]
Pfam domain/function: PF01131 Topoisom_bac; PF01751 Toprim; PF01396 zf-C4_Topoisom [H]
EC number: =5.99.1.2 [H]
Molecular weight: Translated: 28894; Mature: 28894
Theoretical pI: Translated: 5.73; Mature: 5.73
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDLISNGKINWKEVLHQFWFLFIDNVNSVKKLEFTEVLKVISCEMENYIFSSDKSESSRV CCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC CPVCNDGTLELNISKNGIFLGCSKYPECKYTKNVGSGIVDDTDNTQYPKILGIDAATGQE CEEECCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCE IYLKKGPYGLYLQIGNDKSGKRAAIPKNIDANLLDLQMAEKILSLPISLGTHPDTGQEIK EEEEECCEEEEEEECCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEE LGLGKFGAYILYGGKYFSVKNEHNFLDISIENAINIIANNSTSGVIKSLGITEDNKEVFL EECCCCCEEEEECCEEEEECCCCCEEEEEHHCEEEEEECCCCCHHHHCCCCCCCCHHHHH TLIMILQKIDHALYDYLGAK HHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MDLISNGKINWKEVLHQFWFLFIDNVNSVKKLEFTEVLKVISCEMENYIFSSDKSESSRV CCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC CPVCNDGTLELNISKNGIFLGCSKYPECKYTKNVGSGIVDDTDNTQYPKILGIDAATGQE CEEECCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCE IYLKKGPYGLYLQIGNDKSGKRAAIPKNIDANLLDLQMAEKILSLPISLGTHPDTGQEIK EEEEECCEEEEEEECCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEE LGLGKFGAYILYGGKYFSVKNEHNFLDISIENAINIIANNSTSGVIKSLGITEDNKEVFL EECCCCCEEEEECCEEEEECCCCCEEEEEHHCEEEEEECCCCCHHHHCCCCCCCCHHHHH TLIMILQKIDHALYDYLGAK HHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11557893 [H]