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The map label for this gene is nuoC [H]

Identifier: 88658220

GI number: 88658220

Start: 804784

End: 805362

Strand: Direct

Name: nuoC [H]

Synonym: ECH_0788

Alternate gene names: 88658220

Gene position: 804784-805362 (Clockwise)

Preceding gene: 88658003

Following gene: 88657731

Centisome position: 68.42

GC content: 29.02

Gene sequence:

>579_bases
ATGTCAGATAGTAATAATGCAATAGATAATATTAGTACATATATCAATACATCTATAAATGTAGAATGTGTCATAAAAGA
CAATATAACGTTGGAACTACATTCAGATGTACAAAACATCTATAATCATATTTCATTTTTACGTACTGATACAAAGTGTA
AATTTCATATTTTAGTTGATATTTTTGCAATAGATTATCCAACAAGATTGGCTAGATTTGAAGTAATCTATTCATTATTA
AGTATAATCAACAATATAAGAGTATCTTGTAAAGTACCTTTACAAGAGAATGAGAGCATTCCATCTATTACTAACATTTT
CAGTGCTGCAGGATGGTTTGAAAGAGAAGTATTTGATATGTATGGAATAATATTTGCCAATAATCCAGATCTACGCAGAA
TTCTAACAGATTATGGATTTTCTGGCCACCCAATGCTAAAAGATTTTCCTTTAACTGGCTATAAAGAAGTACGGTATGAC
ATATCAAAAAAAGAAGTAGCTTATGAAAACGTAAATTTACAGCAAGATTTCAGATCGTTTGATTTCCTGTCTCCATGGAA
GGAATTAAAGAATGAATGA

Upstream 100 bases:

>100_bases
ATAAACAAGATATACTAGTATTCAACATACATAATATTAATGTTAATACCTTAATTCAGAAAAATAATGTATAGTAAAGA
AAAAATAAAAGAGGATACAG

Downstream 100 bases:

>100_bases
AACAACTATTATTATATAACTAAATATCACACATTTTTTATACATGAAACAACAATTAAACTTAACATCATAAATTCACT
AAACAAACTTTTATGTTGTT

Product: NADH dehydrogenase I, C subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MSDSNNAIDNISTYINTSINVECVIKDNITLELHSDVQNIYNHISFLRTDTKCKFHILVDIFAIDYPTRLARFEVIYSLL
SIINNIRVSCKVPLQENESIPSITNIFSAAGWFEREVFDMYGIIFANNPDLRRILTDYGFSGHPMLKDFPLTGYKEVRYD
ISKKEVAYENVNLQQDFRSFDFLSPWKELKNE

Sequences:

>Translated_192_residues
MSDSNNAIDNISTYINTSINVECVIKDNITLELHSDVQNIYNHISFLRTDTKCKFHILVDIFAIDYPTRLARFEVIYSLL
SIINNIRVSCKVPLQENESIPSITNIFSAAGWFEREVFDMYGIIFANNPDLRRILTDYGFSGHPMLKDFPLTGYKEVRYD
ISKKEVAYENVNLQQDFRSFDFLSPWKELKNE
>Mature_191_residues
SDSNNAIDNISTYINTSINVECVIKDNITLELHSDVQNIYNHISFLRTDTKCKFHILVDIFAIDYPTRLARFEVIYSLLS
IINNIRVSCKVPLQENESIPSITNIFSAAGWFEREVFDMYGIIFANNPDLRRILTDYGFSGHPMLKDFPLTGYKEVRYDI
SKKEVAYENVNLQQDFRSFDFLSPWKELKNE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=170, Percent_Identity=48.2352941176471, Blast_Score=167, Evalue=4e-42,
Organism=Escherichia coli, GI145693162, Length=117, Percent_Identity=35.042735042735, Blast_Score=82, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71990788, Length=167, Percent_Identity=48.502994011976, Blast_Score=160, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI32563621, Length=168, Percent_Identity=48.2142857142857, Blast_Score=160, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24656494, Length=161, Percent_Identity=47.2049689440994, Blast_Score=161, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 22368; Mature: 22236

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSNNAIDNISTYINTSINVECVIKDNITLELHSDVQNIYNHISFLRTDTKCKFHILVD
CCCCCCHHHHHHHHCCCCCEEEEEEECCEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEE
IFAIDYPTRLARFEVIYSLLSIINNIRVSCKVPLQENESIPSITNIFSAAGWFEREVFDM
EEECCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHH
YGIIFANNPDLRRILTDYGFSGHPMLKDFPLTGYKEVRYDISKKEVAYENVNLQQDFRSF
HEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHCCCHHHHHHHC
DFLSPWKELKNE
CCCCHHHHHCCC
>Mature Secondary Structure 
SDSNNAIDNISTYINTSINVECVIKDNITLELHSDVQNIYNHISFLRTDTKCKFHILVD
CCCCCHHHHHHHHCCCCCEEEEEEECCEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEE
IFAIDYPTRLARFEVIYSLLSIINNIRVSCKVPLQENESIPSITNIFSAAGWFEREVFDM
EEECCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHH
YGIIFANNPDLRRILTDYGFSGHPMLKDFPLTGYKEVRYDISKKEVAYENVNLQQDFRSF
HEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHCCCHHHHHHHC
DFLSPWKELKNE
CCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA