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The map label for this gene is nuoA [H]

Identifier: 88658152

GI number: 88658152

Start: 803441

End: 803812

Strand: Direct

Name: nuoA [H]

Synonym: ECH_0786

Alternate gene names: 88658152

Gene position: 803441-803812 (Clockwise)

Preceding gene: 88657960

Following gene: 88658003

Centisome position: 68.31

GC content: 32.53

Gene sequence:

>372_bases
ATGATACAAATGTTTAATATTGCCGAATATGTTCCTGTTCTAATTTTTTTAGCAGTTTCAGGCTTTATTTCATTTCTTTT
TTGCATCTTACCAATGCTTTTAGCTAACCGTAGCCCAGATTTAGAGAAACTTTCCCCATATGAATGTGGATTTGCCCCTC
TTGGAAATTCAAGAAAAATTTTTGACATCCGATTTTATTTAGTCGCAATATTATTCATTATATTCGACCTTGAAATAGCA
TTCTTATTTCCATGGTCTATTTGTCTTTCAGACATAGGCATAAATGGTTTTTGGTCTATGATGGTTTTTTTGGCTATATT
AACAGTAGGTTTTATATATGAGTGGAGCAAAGGTGCACTAGAATGGGAGTAA

Upstream 100 bases:

>100_bases
TTAATGATATGATTAATGATAAAGGGTGTGTAATATATGTTAATAAATTGACATAAAATTAAAACTCTGTAAGTATTTAA
CTATTCACTAAAGTACATAT

Downstream 100 bases:

>100_bases
ACTAGTATGATAAACAAGAATGATTCTGTATTAAATAATCAATTCTGGCAAAGTTACAACCATCAAGGTTTCATGGTAAC
TCAGTTTTCTGACTTAATCA

Product: NADH dehydrogenase I, A subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MIQMFNIAEYVPVLIFLAVSGFISFLFCILPMLLANRSPDLEKLSPYECGFAPLGNSRKIFDIRFYLVAILFIIFDLEIA
FLFPWSICLSDIGINGFWSMMVFLAILTVGFIYEWSKGALEWE

Sequences:

>Translated_123_residues
MIQMFNIAEYVPVLIFLAVSGFISFLFCILPMLLANRSPDLEKLSPYECGFAPLGNSRKIFDIRFYLVAILFIIFDLEIA
FLFPWSICLSDIGINGFWSMMVFLAILTVGFIYEWSKGALEWE
>Mature_123_residues
MIQMFNIAEYVPVLIFLAVSGFISFLFCILPMLLANRSPDLEKLSPYECGFAPLGNSRKIFDIRFYLVAILFIIFDLEIA
FLFPWSICLSDIGINGFWSMMVFLAILTVGFIYEWSKGALEWE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=116, Percent_Identity=34.4827586206897, Blast_Score=68, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 14155; Mature: 14155

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQMFNIAEYVPVLIFLAVSGFISFLFCILPMLLANRSPDLEKLSPYECGFAPLGNSRKI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCH
FDIRFYLVAILFIIFDLEIAFLFPWSICLSDIGINGFWSMMVFLAILTVGFIYEWSKGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
EWE
CCC
>Mature Secondary Structure
MIQMFNIAEYVPVLIFLAVSGFISFLFCILPMLLANRSPDLEKLSPYECGFAPLGNSRKI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCH
FDIRFYLVAILFIIFDLEIAFLFPWSICLSDIGINGFWSMMVFLAILTVGFIYEWSKGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
EWE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA