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The map label for this gene is atoS [C]

Identifier: 88657797

GI number: 88657797

Start: 759946

End: 762432

Strand: Direct

Name: atoS [C]

Synonym: ECH_0755

Alternate gene names: 88657797

Gene position: 759946-762432 (Clockwise)

Preceding gene: 88657893

Following gene: 88658405

Centisome position: 64.61

GC content: 26.82

Gene sequence:

>2487_bases
ATGAAAAAAAGACATACTGACAACACACAAAACAATAAAGTAGATTTTGTAATAAGAAGACATGGATTGTCAGTATGCAA
GCTAGCCATTTTTTTAATAGCTCCACTATTATGCATATCCAGCTTATACCTTTTTAATATATACGATAGCTACATAAATA
TAATTATTAACTGCATATTTACCAGCATTAGTATATTAGCAATATCAATACAATTAAGACAATACTTGTATACTATTGCT
TCTATAGAATATCAAAATATGATTTTTGCTAATTCCTTAAATCATAATACAGAATTTTGTTTAATAATAAAAAATAATGG
TAAAATAATATATGCTGATGCAAGATTCTATGAAAGATTTATAAAAAACCAAGAAAGAAAATTAGACTTATTTGATATAT
TAAAATTAGGTAATATCAGTGAACAAGAAATCGAAGCATTTGAAAATGCATTAAAGAACAAGCTATCAATCAATACATAT
TTTTGTTTAAATACAAAAAATAAAATTTCTAACTTTACACTAATATTAGATCCAGTATTGGAGAACCCAGAAATAGAAAT
TAACTATACAAAAACTGTAAATTTATTTTTTGCTCCTCTTGCAAGACCACAAGAATATTTTGTACTTAAAGCTGTAAAAA
TCACAAAAGAACAAGTATATGAAAGATTAATTCAAAAACATTGTGTAGGAGCATATTTACTTAATCACAGAGGAGTAATA
TTATCCGTAAACGACAGTTTCCTAAAGATGTTTGAATTAAATTCTGTCGAAAATGGTACTACATTTGCTAATTTTTTAAC
AAAAAGTGACAACAAAGAAAAGGTAATAGATAACAATACTGTTACTCTATCCACAACTACAGGAATCACATTTAAAGCAC
ATATATCACAAGCTGCATTTTATGATAAAAATAATCATAGTTATATTTATGGGCTCTTAACTCCAGTAAATTCCGATATT
CTTAATTATCATTTACACCCATGTTTCACAGAAGCTCCAATAGCTATTTTACAATGTAATACAGATGGTAAGATCTTAAA
ATCAAATAATACACTAAAAAGATTAGTTAAACACAGTAAAGAATATATTTTTGAATATATACTACCTTCTTATAATAAAA
AAATTAAAAAGTACTTCCAAAATAACATTGTAAAAAATATGTCATTGGAAGCACAACTCTATAATAACTCATATGTAAAA
ATTCATTTTAATAAATTCATACATCAAAATAACATGTTTATTATATGTTATATAACTGATAGTGAAGATCGTAAAAATCT
AGAAATACAATTAGAGCAATCTCAAAAAATGCAAGCTATTGGACAATTAGCTGGAGGTATAGCTCATGATTTCAACAATA
TTTTAACAGCAATCATAGGTTTTTGCGACTTATTATTGATAAGACATACTGCAACAGATCCTTCTTTTTCAGACATAATG
CAAATAAAACAGAATGCAAACAGAGCAACAAATTTGATAAAGCAATTACTGGCTTTTTCAAGAAAGCAGACTTTACAACC
TAAAATCCTTGACGTAAACAATATAATTGCAGATTTACTACATATGATTAAGAGATTAATCAATGAAAGCATAGAATTAA
AAATTCAATACGAACAAAATATTAATTTAGTAAAAGCAGATTTATGTCAACTAGAACAAGTAATTATCAACCTTGTAGTA
AATGCAAGAGCTGCAATGGAAACAGGGGGACAGCTAAGTATAAAAACCTACAATACGAAAACAGATGTTTTAAAGGTACT
ATTAAAAGACATGTTTTCTCCAGATAAAGAACAAATAGAAGATGGAGAATACGTTGCAATAGAAGTGTCAGATACAGGAC
ATGGAATGGAAGATAAGATAATGAAAAAAATCTTTGACCCATTTTTTTCAACAAAAGAAACAACTGCTGGCATAGGGTTA
GGTTTATCTACAGTGTATGGAATAGTTAAACAAACAGATGGATATATATATGTTAAAAGTATAGTAAATTCAGGTACTAC
TTTTATTATCCTTATCCCTACAGTACATTTATCAAATAATAACGATATTGAAATACCATATAATAAATATTCAAATGAAA
CAAGCACCACAGTACCAGAAGTCAATACTTCTACAACTATTTTACTCATTGAAGATGAAGATCCTGTTAGAATATTTACA
ACAAAAGCATTGACTAAAAAAGGATTCAAAGTCATAGATATAAATTGTGGAGATCAAGCATTAGACATAATCAATAAATA
TCCTATAGATATTGTTATCAGTGATGTAGTGATGCCAAAAATAAGTGGTCCAGAAATTGTAGAACAAATACTAAAAGTAA
AACCAAATATTCAAATCATTTTTATTTCTGGATATGCTGAAGAAGTATTCAATAAATACAGCAATATAGATGTAAGTAAA
ATCAATTTCCTATCTAAACCTTTCACTCTTAAACAACTTACAGAAAAAGTACTAGAAATATCAGACAATTCTTTCTTGCA
GAATTAA

Upstream 100 bases:

>100_bases
TAAATTATGTGATCACCCTCTACCCAACAGTATAATATTCATATAGCAATCTTAGGCATTTATATTATCATGTCATCAGT
AAGTATTAAGTCATATTGAA

Downstream 100 bases:

>100_bases
ATATAACCTTTATTACATACAAGCAATATTTAGCTATAAAACTTGATCTAAACTCGTTTTTACAATAAAAACCATAATAT
CTAAACTACAATAAAATTAT

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 828; Mature: 828

Protein sequence:

>828_residues
MKKRHTDNTQNNKVDFVIRRHGLSVCKLAIFLIAPLLCISSLYLFNIYDSYINIIINCIFTSISILAISIQLRQYLYTIA
SIEYQNMIFANSLNHNTEFCLIIKNNGKIIYADARFYERFIKNQERKLDLFDILKLGNISEQEIEAFENALKNKLSINTY
FCLNTKNKISNFTLILDPVLENPEIEINYTKTVNLFFAPLARPQEYFVLKAVKITKEQVYERLIQKHCVGAYLLNHRGVI
LSVNDSFLKMFELNSVENGTTFANFLTKSDNKEKVIDNNTVTLSTTTGITFKAHISQAAFYDKNNHSYIYGLLTPVNSDI
LNYHLHPCFTEAPIAILQCNTDGKILKSNNTLKRLVKHSKEYIFEYILPSYNKKIKKYFQNNIVKNMSLEAQLYNNSYVK
IHFNKFIHQNNMFIICYITDSEDRKNLEIQLEQSQKMQAIGQLAGGIAHDFNNILTAIIGFCDLLLIRHTATDPSFSDIM
QIKQNANRATNLIKQLLAFSRKQTLQPKILDVNNIIADLLHMIKRLINESIELKIQYEQNINLVKADLCQLEQVIINLVV
NARAAMETGGQLSIKTYNTKTDVLKVLLKDMFSPDKEQIEDGEYVAIEVSDTGHGMEDKIMKKIFDPFFSTKETTAGIGL
GLSTVYGIVKQTDGYIYVKSIVNSGTTFIILIPTVHLSNNNDIEIPYNKYSNETSTTVPEVNTSTTILLIEDEDPVRIFT
TKALTKKGFKVIDINCGDQALDIINKYPIDIVISDVVMPKISGPEIVEQILKVKPNIQIIFISGYAEEVFNKYSNIDVSK
INFLSKPFTLKQLTEKVLEISDNSFLQN

Sequences:

>Translated_828_residues
MKKRHTDNTQNNKVDFVIRRHGLSVCKLAIFLIAPLLCISSLYLFNIYDSYINIIINCIFTSISILAISIQLRQYLYTIA
SIEYQNMIFANSLNHNTEFCLIIKNNGKIIYADARFYERFIKNQERKLDLFDILKLGNISEQEIEAFENALKNKLSINTY
FCLNTKNKISNFTLILDPVLENPEIEINYTKTVNLFFAPLARPQEYFVLKAVKITKEQVYERLIQKHCVGAYLLNHRGVI
LSVNDSFLKMFELNSVENGTTFANFLTKSDNKEKVIDNNTVTLSTTTGITFKAHISQAAFYDKNNHSYIYGLLTPVNSDI
LNYHLHPCFTEAPIAILQCNTDGKILKSNNTLKRLVKHSKEYIFEYILPSYNKKIKKYFQNNIVKNMSLEAQLYNNSYVK
IHFNKFIHQNNMFIICYITDSEDRKNLEIQLEQSQKMQAIGQLAGGIAHDFNNILTAIIGFCDLLLIRHTATDPSFSDIM
QIKQNANRATNLIKQLLAFSRKQTLQPKILDVNNIIADLLHMIKRLINESIELKIQYEQNINLVKADLCQLEQVIINLVV
NARAAMETGGQLSIKTYNTKTDVLKVLLKDMFSPDKEQIEDGEYVAIEVSDTGHGMEDKIMKKIFDPFFSTKETTAGIGL
GLSTVYGIVKQTDGYIYVKSIVNSGTTFIILIPTVHLSNNNDIEIPYNKYSNETSTTVPEVNTSTTILLIEDEDPVRIFT
TKALTKKGFKVIDINCGDQALDIINKYPIDIVISDVVMPKISGPEIVEQILKVKPNIQIIFISGYAEEVFNKYSNIDVSK
INFLSKPFTLKQLTEKVLEISDNSFLQN
>Mature_828_residues
MKKRHTDNTQNNKVDFVIRRHGLSVCKLAIFLIAPLLCISSLYLFNIYDSYINIIINCIFTSISILAISIQLRQYLYTIA
SIEYQNMIFANSLNHNTEFCLIIKNNGKIIYADARFYERFIKNQERKLDLFDILKLGNISEQEIEAFENALKNKLSINTY
FCLNTKNKISNFTLILDPVLENPEIEINYTKTVNLFFAPLARPQEYFVLKAVKITKEQVYERLIQKHCVGAYLLNHRGVI
LSVNDSFLKMFELNSVENGTTFANFLTKSDNKEKVIDNNTVTLSTTTGITFKAHISQAAFYDKNNHSYIYGLLTPVNSDI
LNYHLHPCFTEAPIAILQCNTDGKILKSNNTLKRLVKHSKEYIFEYILPSYNKKIKKYFQNNIVKNMSLEAQLYNNSYVK
IHFNKFIHQNNMFIICYITDSEDRKNLEIQLEQSQKMQAIGQLAGGIAHDFNNILTAIIGFCDLLLIRHTATDPSFSDIM
QIKQNANRATNLIKQLLAFSRKQTLQPKILDVNNIIADLLHMIKRLINESIELKIQYEQNINLVKADLCQLEQVIINLVV
NARAAMETGGQLSIKTYNTKTDVLKVLLKDMFSPDKEQIEDGEYVAIEVSDTGHGMEDKIMKKIFDPFFSTKETTAGIGL
GLSTVYGIVKQTDGYIYVKSIVNSGTTFIILIPTVHLSNNNDIEIPYNKYSNETSTTVPEVNTSTTILLIEDEDPVRIFT
TKALTKKGFKVIDINCGDQALDIINKYPIDIVISDVVMPKISGPEIVEQILKVKPNIQIIFISGYAEEVFNKYSNIDVSK
INFLSKPFTLKQLTEKVLEISDNSFLQN

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=268, Percent_Identity=27.2388059701493, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790436, Length=252, Percent_Identity=28.968253968254, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI145693157, Length=299, Percent_Identity=27.4247491638796, Blast_Score=83, Evalue=9e-17,
Organism=Escherichia coli, GI1788713, Length=392, Percent_Identity=22.4489795918367, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI48994928, Length=423, Percent_Identity=22.2222222222222, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1790300, Length=340, Percent_Identity=24.1176470588235, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081816, Length=186, Percent_Identity=24.7311827956989, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 94603; Mature: 94603

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRHTDNTQNNKVDFVIRRHGLSVCKLAIFLIAPLLCISSLYLFNIYDSYINIIINCIF
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSISILAISIQLRQYLYTIASIEYQNMIFANSLNHNTEFCLIIKNNGKIIYADARFYERF
HHHHHHHHHHHHHHHHHHHHHCCHHCEEEEECCCCCCEEEEEEECCCEEEEECHHHHHHH
IKNQERKLDLFDILKLGNISEQEIEAFENALKNKLSINTYFCLNTKNKISNFTLILDPVL
HCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEEECCC
ENPEIEINYTKTVNLFFAPLARPQEYFVLKAVKITKEQVYERLIQKHCVGAYLLNHRGVI
CCCEEEEEEEEEEEEEEECCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHEECCCCEE
LSVNDSFLKMFELNSVENGTTFANFLTKSDNKEKVIDNNTVTLSTTTGITFKAHISQAAF
EEECHHHEEHEECCCCCCCCHHHHHHHCCCCCCEEECCCEEEEEEECCEEEEEECCHHHE
YDKNNHSYIYGLLTPVNSDILNYHLHPCFTEAPIAILQCNTDGKILKSNNTLKRLVKHSK
EECCCCCEEEEEECCCCCCHHEEECCCCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHH
EYIFEYILPSYNKKIKKYFQNNIVKNMSLEAQLYNNSYVKIHFNKFIHQNNMFIICYITD
HHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEEEEEEECCCEEEEEEEEC
SEDRKNLEIQLEQSQKMQAIGQLAGGIAHDFNNILTAIIGFCDLLLIRHTATDPSFSDIM
CCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
QIKQNANRATNLIKQLLAFSRKQTLQPKILDVNNIIADLLHMIKRLINESIELKIQYEQN
HHHHCCHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHCCCCEEEEEEECCC
INLVKADLCQLEQVIINLVVNARAAMETGGQLSIKTYNTKTDVLKVLLKDMFSPDKEQIE
CCEEHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCCHHHCC
DGEYVAIEVSDTGHGMEDKIMKKIFDPFFSTKETTAGIGLGLSTVYGIVKQTDGYIYVKS
CCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEE
IVNSGTTFIILIPTVHLSNNNDIEIPYNKYSNETSTTVPEVNTSTTILLIEDEDPVRIFT
HHCCCCEEEEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEE
TKALTKKGFKVIDINCGDQALDIINKYPIDIVISDVVMPKISGPEIVEQILKVKPNIQII
EHHHHHCCCEEEEECCCHHHHHHHHCCCCEEEEECHHCCCCCCHHHHHHHHHCCCCEEEE
FISGYAEEVFNKYSNIDVSKINFLSKPFTLKQLTEKVLEISDNSFLQN
EEECCHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure
MKKRHTDNTQNNKVDFVIRRHGLSVCKLAIFLIAPLLCISSLYLFNIYDSYINIIINCIF
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSISILAISIQLRQYLYTIASIEYQNMIFANSLNHNTEFCLIIKNNGKIIYADARFYERF
HHHHHHHHHHHHHHHHHHHHHCCHHCEEEEECCCCCCEEEEEEECCCEEEEECHHHHHHH
IKNQERKLDLFDILKLGNISEQEIEAFENALKNKLSINTYFCLNTKNKISNFTLILDPVL
HCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEEEECCC
ENPEIEINYTKTVNLFFAPLARPQEYFVLKAVKITKEQVYERLIQKHCVGAYLLNHRGVI
CCCEEEEEEEEEEEEEEECCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHEECCCCEE
LSVNDSFLKMFELNSVENGTTFANFLTKSDNKEKVIDNNTVTLSTTTGITFKAHISQAAF
EEECHHHEEHEECCCCCCCCHHHHHHHCCCCCCEEECCCEEEEEEECCEEEEEECCHHHE
YDKNNHSYIYGLLTPVNSDILNYHLHPCFTEAPIAILQCNTDGKILKSNNTLKRLVKHSK
EECCCCCEEEEEECCCCCCHHEEECCCCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHH
EYIFEYILPSYNKKIKKYFQNNIVKNMSLEAQLYNNSYVKIHFNKFIHQNNMFIICYITD
HHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEEEEEEECCCEEEEEEEEC
SEDRKNLEIQLEQSQKMQAIGQLAGGIAHDFNNILTAIIGFCDLLLIRHTATDPSFSDIM
CCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
QIKQNANRATNLIKQLLAFSRKQTLQPKILDVNNIIADLLHMIKRLINESIELKIQYEQN
HHHHCCHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHCCCCEEEEEEECCC
INLVKADLCQLEQVIINLVVNARAAMETGGQLSIKTYNTKTDVLKVLLKDMFSPDKEQIE
CCEEHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCCHHHCC
DGEYVAIEVSDTGHGMEDKIMKKIFDPFFSTKETTAGIGLGLSTVYGIVKQTDGYIYVKS
CCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEE
IVNSGTTFIILIPTVHLSNNNDIEIPYNKYSNETSTTVPEVNTSTTILLIEDEDPVRIFT
HHCCCCEEEEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEE
TKALTKKGFKVIDINCGDQALDIINKYPIDIVISDVVMPKISGPEIVEQILKVKPNIQII
EHHHHHCCCEEEEECCCHHHHHHHHCCCCEEEEECHHCCCCCCHHHHHHHHHCCCCEEEE
FISGYAEEVFNKYSNIDVSKINFLSKPFTLKQLTEKVLEISDNSFLQN
EEECCHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA