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The map label for this gene is ftsK [H]

Identifier: 88657569

GI number: 88657569

Start: 914420

End: 916903

Strand: Reverse

Name: ftsK [H]

Synonym: ECH_0890

Alternate gene names: 88657569

Gene position: 916903-914420 (Counterclockwise)

Preceding gene: 88657974

Following gene: 88658057

Centisome position: 77.95

GC content: 33.45

Gene sequence:

>2484_bases
ATGCTTTGCGTTACTATTTTGGGTAAGATAGTTGTGAGTATAAAATCTGTCCTTAATAAAACTTTTGTTTCCTTTAAGAT
ATTTTTACTATCTTTTGTGGTAGCATTTGTTTCTTTGTCAATTCTTACTTATCATGAAAATGATTTATCTTTCAATCTGG
CGACTGACTCTCCTGTGAGAAATTTAGGTGGCGTTGTTGGGTCGCATCTAGCTGATATTTTTGTACAAATATTTGGTATA
TCTAGCCTTATAGCAATTCCTTTAATGGTCTTTTGCGTTGTTAATATACTATGTCGTGTCAATAGGAATATTTACCTGTA
CCTTGGTAGCAGTTTGATGATTATGGTTGGAATAAGTGGATTGGTATCGAATGTTTCTCTAAAGGTCATCCATAAATACT
ATTATGGTGGTGTTCTAGGTATCTATTTTCAAAGCTGTCCAATTATTGTATTGCTTGCTATAGTATTGTTGGGTACTGCT
GGAATTATTGGTTGGAAAAAAATTGTATATCTTTATGATATCTTATTAAAAATGTTTAGTAGGATAATTCATAAATCTAA
CAATATTAGTGATACTGTTATAAGAGAAGAAATCTCTCAAAATGTAGGACAAGCTCAAGAGTATTATAATATAGAAGATT
CATTGGATGAGAGAGAATTTACAGAGGAAGAAGAGGAAATAGAGGAAGACGAATTAACGAAAGAGTTAATAGAAGAAGAA
ATAGAAGAGGAAGAATCAATAGAAGAGTTTATGGAAGAGGAGGTGGAAGGAGAGGAATTAGCAGAAGAATTAGATTTTCC
AGATGAAGAAGAAGGGTTAGAATTTCAAGTTGAAGAAGATGATGATGAATGTGAAGAAGAAGATGAGGAAAGTAATTACG
ATGAAGAATGTCATGATAAATATGATGATAAAGACGATTATATTGATGACAGTAATGAAAAAGAGATAGTAGTTTATAAG
AGACCTCAGGCAACTCCTCAAGTAGTTCAAGAAAAAAAAAAGTATAAAGAATTTGTCCTACCTAGTGTTGATTATTTATC
AAAACCTAATCCAGTAGATAAAAGAGAGTTTCATCCAGATGATAATGTTGTCAATTTGCTTAATAAAGTACTTAAGGATT
TTTCTATACATGGAAACATAGTTAATATTAGGTATGGTCCAGTAGTAACATTATATGAGTTTGAACCATCTGCTGGTACT
AAATCATCAAGGGTTATAGGATTGTCTGATGATATTGCTCGTTCAATGAGTGCTTTGTCAACACGTATATCAGTTATTCC
TGGAAGAAATGTTATGGGTATAGAACTACCAAATCACTATAGGGAAATAGTGATGTTACGTGATTTATTTGAAAGTGAAC
AGTATAGGGATTCTAGGCTTAAATTACCCATAGCTTTAGGAAAGGGTATAGATGGGGAAGTAGTTATTGCTGATTTAGTA
AAAATGCCGCATCTTCTTATTGCTGGTACTACAGGGTCTGGAAAATCTGTAGCAATTAATACTATGATTTTATCTCTGAT
CTACAGTTTAACTCCAGATCAATGCAAAATGATTATGATTGATCCTAAAGTACTAGAATTGTCAGTCTATAATTCTATTC
CACATTTGTTAACTCCAGTAGTGACTGAATCCAAAAAGGCTATTGCTGCTTTAAAGTGGGTAGTAAGTGAAATGGAAAAT
CGTTACCGGTTAATGTCTGATATTGGAGTACGTAATATTGTTAGTTATAATGATAAAATTAAAGAAGCAATTGATGAGAA
TAGAACTCTAGAAAAAGTATTACAGACAGGGTTTGATAAAGAGACAGGGGAGGCAATTTTCGAAAGAATTGCAATAGAGC
CTAGTGTTTTTCCTTACATTGTAGTGATAGTAGATGAAATGGCAGATTTAATGCTTGTAGCTGGGAAAGAAATTGAATCT
TCGATACAAAGATTATCTCAGATGGCAAGGGCTGCTGGAATTCATATAATTATGGCAACTCAGCGTCCTTCTGTTGATAT
AATCACAGGGGTAGTAAAAGCAAATTTCCCAACAAGAATTAGCTTTGCCGTAACATCGAAGATAGATAGTAGAACTATCC
TTGGTGAACAAGGAGCAGAGCAGTTACTTGGTATGGGTGACATGCTGTATATGGTATCTGGTGGTAGAATAATACGTGTG
CATGGAGCTTTTGTTAGCGATGATGAAATACAGAATATAGTTGAATATTTGAGGTCTCAAGGAACTCCAGATTATATAGA
AGGTATTACACGGATCCAACAAGATTATGATTATTGTATAGATGATAATATTCCTGAACGGGATGATGAATTGTATAAAC
AAGCAGTGTCGATAGTAATAAGGGATCGAAGAACTTCTATTAGCTATATCCAGAGACAATTAAGAATAGGATATAATAGA
GCTGCAAATTTAGTAGAGCGTATGGAAAGAGATGGTGTTATTGGAGTTGCAAGTGCTGGAAAGCGAGAAATATTGCTTGA
ATAG

Upstream 100 bases:

>100_bases
CCTGCCTTGAATTTTATCAGGAAGATTCTGCCTTTTACTATTTCCTATAATTTTGATCTTTCACCACTTGTATTGTTGAT
ATTTATTAATTTTATAAGAT

Downstream 100 bases:

>100_bases
TATCGAATATGTAAACAATGATGATTATTACTACCTTAGATTATTAAAAAATTACATCAGCATTTAAAAGTTGTAAGTTA
GTTGTACAGTTATACATTTT

Product: putative cell division protein FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 827; Mature: 827

Protein sequence:

>827_residues
MLCVTILGKIVVSIKSVLNKTFVSFKIFLLSFVVAFVSLSILTYHENDLSFNLATDSPVRNLGGVVGSHLADIFVQIFGI
SSLIAIPLMVFCVVNILCRVNRNIYLYLGSSLMIMVGISGLVSNVSLKVIHKYYYGGVLGIYFQSCPIIVLLAIVLLGTA
GIIGWKKIVYLYDILLKMFSRIIHKSNNISDTVIREEISQNVGQAQEYYNIEDSLDEREFTEEEEEIEEDELTKELIEEE
IEEEESIEEFMEEEVEGEELAEELDFPDEEEGLEFQVEEDDDECEEEDEESNYDEECHDKYDDKDDYIDDSNEKEIVVYK
RPQATPQVVQEKKKYKEFVLPSVDYLSKPNPVDKREFHPDDNVVNLLNKVLKDFSIHGNIVNIRYGPVVTLYEFEPSAGT
KSSRVIGLSDDIARSMSALSTRISVIPGRNVMGIELPNHYREIVMLRDLFESEQYRDSRLKLPIALGKGIDGEVVIADLV
KMPHLLIAGTTGSGKSVAINTMILSLIYSLTPDQCKMIMIDPKVLELSVYNSIPHLLTPVVTESKKAIAALKWVVSEMEN
RYRLMSDIGVRNIVSYNDKIKEAIDENRTLEKVLQTGFDKETGEAIFERIAIEPSVFPYIVVIVDEMADLMLVAGKEIES
SIQRLSQMARAAGIHIIMATQRPSVDIITGVVKANFPTRISFAVTSKIDSRTILGEQGAEQLLGMGDMLYMVSGGRIIRV
HGAFVSDDEIQNIVEYLRSQGTPDYIEGITRIQQDYDYCIDDNIPERDDELYKQAVSIVIRDRRTSISYIQRQLRIGYNR
AANLVERMERDGVIGVASAGKREILLE

Sequences:

>Translated_827_residues
MLCVTILGKIVVSIKSVLNKTFVSFKIFLLSFVVAFVSLSILTYHENDLSFNLATDSPVRNLGGVVGSHLADIFVQIFGI
SSLIAIPLMVFCVVNILCRVNRNIYLYLGSSLMIMVGISGLVSNVSLKVIHKYYYGGVLGIYFQSCPIIVLLAIVLLGTA
GIIGWKKIVYLYDILLKMFSRIIHKSNNISDTVIREEISQNVGQAQEYYNIEDSLDEREFTEEEEEIEEDELTKELIEEE
IEEEESIEEFMEEEVEGEELAEELDFPDEEEGLEFQVEEDDDECEEEDEESNYDEECHDKYDDKDDYIDDSNEKEIVVYK
RPQATPQVVQEKKKYKEFVLPSVDYLSKPNPVDKREFHPDDNVVNLLNKVLKDFSIHGNIVNIRYGPVVTLYEFEPSAGT
KSSRVIGLSDDIARSMSALSTRISVIPGRNVMGIELPNHYREIVMLRDLFESEQYRDSRLKLPIALGKGIDGEVVIADLV
KMPHLLIAGTTGSGKSVAINTMILSLIYSLTPDQCKMIMIDPKVLELSVYNSIPHLLTPVVTESKKAIAALKWVVSEMEN
RYRLMSDIGVRNIVSYNDKIKEAIDENRTLEKVLQTGFDKETGEAIFERIAIEPSVFPYIVVIVDEMADLMLVAGKEIES
SIQRLSQMARAAGIHIIMATQRPSVDIITGVVKANFPTRISFAVTSKIDSRTILGEQGAEQLLGMGDMLYMVSGGRIIRV
HGAFVSDDEIQNIVEYLRSQGTPDYIEGITRIQQDYDYCIDDNIPERDDELYKQAVSIVIRDRRTSISYIQRQLRIGYNR
AANLVERMERDGVIGVASAGKREILLE
>Mature_827_residues
MLCVTILGKIVVSIKSVLNKTFVSFKIFLLSFVVAFVSLSILTYHENDLSFNLATDSPVRNLGGVVGSHLADIFVQIFGI
SSLIAIPLMVFCVVNILCRVNRNIYLYLGSSLMIMVGISGLVSNVSLKVIHKYYYGGVLGIYFQSCPIIVLLAIVLLGTA
GIIGWKKIVYLYDILLKMFSRIIHKSNNISDTVIREEISQNVGQAQEYYNIEDSLDEREFTEEEEEIEEDELTKELIEEE
IEEEESIEEFMEEEVEGEELAEELDFPDEEEGLEFQVEEDDDECEEEDEESNYDEECHDKYDDKDDYIDDSNEKEIVVYK
RPQATPQVVQEKKKYKEFVLPSVDYLSKPNPVDKREFHPDDNVVNLLNKVLKDFSIHGNIVNIRYGPVVTLYEFEPSAGT
KSSRVIGLSDDIARSMSALSTRISVIPGRNVMGIELPNHYREIVMLRDLFESEQYRDSRLKLPIALGKGIDGEVVIADLV
KMPHLLIAGTTGSGKSVAINTMILSLIYSLTPDQCKMIMIDPKVLELSVYNSIPHLLTPVVTESKKAIAALKWVVSEMEN
RYRLMSDIGVRNIVSYNDKIKEAIDENRTLEKVLQTGFDKETGEAIFERIAIEPSVFPYIVVIVDEMADLMLVAGKEIES
SIQRLSQMARAAGIHIIMATQRPSVDIITGVVKANFPTRISFAVTSKIDSRTILGEQGAEQLLGMGDMLYMVSGGRIIRV
HGAFVSDDEIQNIVEYLRSQGTPDYIEGITRIQQDYDYCIDDNIPERDDELYKQAVSIVIRDRRTSISYIQRQLRIGYNR
AANLVERMERDGVIGVASAGKREILLE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=494, Percent_Identity=48.7854251012146, Blast_Score=463, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 93461; Mature: 93461

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCVTILGKIVVSIKSVLNKTFVSFKIFLLSFVVAFVSLSILTYHENDLSFNLATDSPVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCHH
NLGGVVGSHLADIFVQIFGISSLIAIPLMVFCVVNILCRVNRNIYLYLGSSLMIMVGISG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
LVSNVSLKVIHKYYYGGVLGIYFQSCPIIVLLAIVLLGTAGIIGWKKIVYLYDILLKMFS
HHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RIIHKSNNISDTVIREEISQNVGQAQEYYNIEDSLDEREFTEEEEEIEEDELTKELIEEE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHCCCHHHHHHHHHHHHHHHHHH
IEEEESIEEFMEEEVEGEELAEELDFPDEEEGLEFQVEEDDDECEEEDEESNYDEECHDK
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEECCCCHHHHCCHHCCCCCHHHHHC
YDDKDDYIDDSNEKEIVVYKRPQATPQVVQEKKKYKEFVLPSVDYLSKPNPVDKREFHPD
CCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCC
DNVVNLLNKVLKDFSIHGNIVNIRYGPVVTLYEFEPSAGTKSSRVIGLSDDIARSMSALS
HHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCCCCCCEEEECCHHHHHHHHHHH
TRISVIPGRNVMGIELPNHYREIVMLRDLFESEQYRDSRLKLPIALGKGIDGEVVIADLV
HHHEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHH
KMPHLLIAGTTGSGKSVAINTMILSLIYSLTPDQCKMIMIDPKVLELSVYNSIPHLLTPV
HCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEHHHCCHHHHHHH
VTESKKAIAALKWVVSEMENRYRLMSDIGVRNIVSYNDKIKEAIDENRTLEKVLQTGFDK
HHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
ETGEAIFERIAIEPSVFPYIVVIVDEMADLMLVAGKEIESSIQRLSQMARAAGIHIIMAT
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCEEEEEEC
QRPSVDIITGVVKANFPTRISFAVTSKIDSRTILGEQGAEQLLGMGDMLYMVSGGRIIRV
CCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCHHHHHCCCCEEEEECCCEEEEE
HGAFVSDDEIQNIVEYLRSQGTPDYIEGITRIQQDYDYCIDDNIPERDDELYKQAVSIVI
ECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
RDRRTSISYIQRQLRIGYNRAANLVERMERDGVIGVASAGKREILLE
HCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MLCVTILGKIVVSIKSVLNKTFVSFKIFLLSFVVAFVSLSILTYHENDLSFNLATDSPVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCCHH
NLGGVVGSHLADIFVQIFGISSLIAIPLMVFCVVNILCRVNRNIYLYLGSSLMIMVGISG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
LVSNVSLKVIHKYYYGGVLGIYFQSCPIIVLLAIVLLGTAGIIGWKKIVYLYDILLKMFS
HHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RIIHKSNNISDTVIREEISQNVGQAQEYYNIEDSLDEREFTEEEEEIEEDELTKELIEEE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHCCCHHHHHHHHHHHHHHHHHH
IEEEESIEEFMEEEVEGEELAEELDFPDEEEGLEFQVEEDDDECEEEDEESNYDEECHDK
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEECCCCHHHHCCHHCCCCCHHHHHC
YDDKDDYIDDSNEKEIVVYKRPQATPQVVQEKKKYKEFVLPSVDYLSKPNPVDKREFHPD
CCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCC
DNVVNLLNKVLKDFSIHGNIVNIRYGPVVTLYEFEPSAGTKSSRVIGLSDDIARSMSALS
HHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCCCCCCEEEECCHHHHHHHHHHH
TRISVIPGRNVMGIELPNHYREIVMLRDLFESEQYRDSRLKLPIALGKGIDGEVVIADLV
HHHEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHH
KMPHLLIAGTTGSGKSVAINTMILSLIYSLTPDQCKMIMIDPKVLELSVYNSIPHLLTPV
HCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEHHHCCHHHHHHH
VTESKKAIAALKWVVSEMENRYRLMSDIGVRNIVSYNDKIKEAIDENRTLEKVLQTGFDK
HHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
ETGEAIFERIAIEPSVFPYIVVIVDEMADLMLVAGKEIESSIQRLSQMARAAGIHIIMAT
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCEEEEEEC
QRPSVDIITGVVKANFPTRISFAVTSKIDSRTILGEQGAEQLLGMGDMLYMVSGGRIIRV
CCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCHHHHHCCCCEEEEECCCEEEEE
HGAFVSDDEIQNIVEYLRSQGTPDYIEGITRIQQDYDYCIDDNIPERDDELYKQAVSIVI
ECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
RDRRTSISYIQRQLRIGYNRAANLVERMERDGVIGVASAGKREILLE
HCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]