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The map label for this gene is gmk

Identifier: 88607831

GI number: 88607831

Start: 150021

End: 150308

Strand: Reverse

Name: gmk

Synonym: APH_0147

Alternate gene names: 88607831

Gene position: 150308-150021 (Counterclockwise)

Preceding gene: 88607203

Following gene: 88607478

Centisome position: 10.22

GC content: 43.06

Gene sequence:

>288_bases
ATGAGAGAGCACGTAGTGAGCATATTCATAATGCCCCCTTCTATGGAAGAACTGCGTAGGAGATTATGTGGTAGAAGAGC
TGATGATTCAGAGGTTGTGGAAGCAAGGCTAAAAGGAGCAGCGTTTGAGATCAGTCACTGCGAAGCTTACGACTACGTAA
TAGTAAACGAAGATATAGAGGAAACAGCAGACAGAATTAGCAATATCCTGAGGGCAGAACAGATGAAAACTTGCAGGCAA
GTTGGGCTGAGGGAATTATTAGAGAGTAGGTTCCCTATAGAAGATTAA

Upstream 100 bases:

>100_bases
CTACGGTGTTCCCCGCAAGAATCTAGAAGACAATGTAGATAAGGGAGTCAGCACGTTACTAGTAATTGACTGGCAAGGAG
CTTTCAAGTTCATGGAGATG

Downstream 100 bases:

>100_bases
GCAATCTGTAGAATAGAATGCTGGTTGCACATTAACTGATATGTAGAACTCTATATTATTGGTCTCTGTGTTTTGCTTTT
AGTATCATAAAATGCGTATA

Product: guanylate kinase, truncation

Products: NA

Alternate protein names: GMP kinase

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MREHVVSIFIMPPSMEELRRRLCGRRADDSEVVEARLKGAAFEISHCEAYDYVIVNEDIEETADRISNILRAEQMKTCRQ
VGLRELLESRFPIED

Sequences:

>Translated_95_residues
MREHVVSIFIMPPSMEELRRRLCGRRADDSEVVEARLKGAAFEISHCEAYDYVIVNEDIEETADRISNILRAEQMKTCRQ
VGLRELLESRFPIED
>Mature_95_residues
MREHVVSIFIMPPSMEELRRRLCGRRADDSEVVEARLKGAAFEISHCEAYDYVIVNEDIEETADRISNILRAEQMKTCRQ
VGLRELLESRFPIED

Specific function: Essential for recycling GMP and indirectly, cGMP

COG id: COG0194

COG function: function code F; Guanylate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate kinase-like domain

Homologues:

Organism=Escherichia coli, GI1790080, Length=77, Percent_Identity=46.7532467532467, Blast_Score=74, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KGUA_ANAPZ (Q2GLF7)

Other databases:

- EMBL:   CP000235
- RefSeq:   YP_504794.1
- PDB:   3LNC
- PDBsum:   3LNC
- ProteinModelPortal:   Q2GLF7
- SMR:   Q2GLF7
- STRING:   Q2GLF7
- GeneID:   3930277
- GenomeReviews:   CP000235_GR
- KEGG:   aph:APH_0170
- NMPDR:   fig|212042.5.peg.165
- TIGR:   APH_0170
- eggNOG:   COG0194
- HOGENOM:   HBG671982
- OMA:   DIDWQGT
- PhylomeDB:   Q2GLF7
- ProtClustDB:   PRK00300
- BioCyc:   APHA212042:APH_0170-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00328
- InterPro:   IPR008144
- InterPro:   IPR008145
- InterPro:   IPR020590
- InterPro:   IPR017665
- SMART:   SM00072
- TIGRFAMs:   TIGR03263

Pfam domain/function: PF00625 Guanylate_kin

EC number: =2.7.4.8

Molecular weight: Translated: 11084; Mature: 11084

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00856 GUANYLATE_KINASE_1; PS50052 GUANYLATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREHVVSIFIMPPSMEELRRRLCGRRADDSEVVEARLKGAAFEISHCEAYDYVIVNEDIE
CCCCEEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCCCEEEECCCHH
ETADRISNILRAEQMKTCRQVGLRELLESRFPIED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MREHVVSIFIMPPSMEELRRRLCGRRADDSEVVEARLKGAAFEISHCEAYDYVIVNEDIE
CCCCEEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCCCEEEECCCHH
ETADRISNILRAEQMKTCRQVGLRELLESRFPIED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA