Click here to switch to the map view.

The map label for this gene is ribH [H]

Identifier: 88607155

GI number: 88607155

Start: 558970

End: 559428

Strand: Reverse

Name: ribH [H]

Synonym: APH_0539

Alternate gene names: 88607155

Gene position: 559428-558970 (Counterclockwise)

Preceding gene: 88607700

Following gene: 88607519

Centisome position: 38.02

GC content: 43.79

Gene sequence:

>459_bases
ATGGGAAGTGTTATGGATGCTAAATTGAGTGCTTTGATTGTTGTTGGGTCTTTTCATACTGAGGTTTGTGGACAGCTTGT
AAAGGGGGCTATAGAAAGGATCAAGGCTTATAATGCTGCTGCAGAATGTGAGGTTATTGAAGTGCCTGGGGCTCTAGAGG
TACCACCGGCAATCTCTTTTGCTGTCATGAGTGATAGGGAGTCTTACGATGGGTTTGTAGCGTTGGGATGTGTTCTAAAG
GGATATACAGACCATAATATTCATGTTTCGAACTCGGCTTTTTCGGCCCTGAGTGACATTGCTGTGCAACATGCAGTGCC
GATGGGTACGGGTATAATAACTGCTGATACTATGAGTTTGGCTATGGAAAGGGCTGATGTAAATGGAATAAATATAGGTG
GTAGAGCGGCTGCTGCAATGTTAAGAATGCTGGAATTGTATAGAAGGTTTTTGGGCTAG

Upstream 100 bases:

>100_bases
CTGGATATGTAGCAACGTTATAACCATTCTGCAGCAAATCGTAATCAGGTACTTTGTCTGTAGAAAAGAGCTAGGTGCAA
ATGGTTAGTGTGTAGTCGTG

Downstream 100 bases:

>100_bases
CATGATGGAAAAAGTGGTTAATGGAGCTCACGATGACATGCCATGGCATGTTGGAAAAACTTCTGCTAGATTCCTAGCGG
TACAGGGTGCTTACGCCATG

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MGSVMDAKLSALIVVGSFHTEVCGQLVKGAIERIKAYNAAAECEVIEVPGALEVPPAISFAVMSDRESYDGFVALGCVLK
GYTDHNIHVSNSAFSALSDIAVQHAVPMGTGIITADTMSLAMERADVNGINIGGRAAAAMLRMLELYRRFLG

Sequences:

>Translated_152_residues
MGSVMDAKLSALIVVGSFHTEVCGQLVKGAIERIKAYNAAAECEVIEVPGALEVPPAISFAVMSDRESYDGFVALGCVLK
GYTDHNIHVSNSAFSALSDIAVQHAVPMGTGIITADTMSLAMERADVNGINIGGRAAAAMLRMLELYRRFLG
>Mature_151_residues
GSVMDAKLSALIVVGSFHTEVCGQLVKGAIERIKAYNAAAECEVIEVPGALEVPPAISFAVMSDRESYDGFVALGCVLKG
YTDHNIHVSNSAFSALSDIAVQHAVPMGTGIITADTMSLAMERADVNGINIGGRAAAAMLRMLELYRRFLG

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=145, Percent_Identity=28.9655172413793, Blast_Score=68, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16019; Mature: 15888

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSVMDAKLSALIVVGSFHTEVCGQLVKGAIERIKAYNAAAECEVIEVPGALEVPPAISF
CCCCHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEE
AVMSDRESYDGFVALGCVLKGYTDHNIHVSNSAFSALSDIAVQHAVPMGTGIITADTMSL
EEECCCCCCCCHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCCEEEHHHHHH
AMERADVNGINIGGRAAAAMLRMLELYRRFLG
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GSVMDAKLSALIVVGSFHTEVCGQLVKGAIERIKAYNAAAECEVIEVPGALEVPPAISF
CCCHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEE
AVMSDRESYDGFVALGCVLKGYTDHNIHVSNSAFSALSDIAVQHAVPMGTGIITADTMSL
EEECCCCCCCCHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCCEEEHHHHHH
AMERADVNGINIGGRAAAAMLRMLELYRRFLG
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA