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The map label for this gene is rpe [H]

Identifier: 88607073

GI number: 88607073

Start: 2838

End: 3548

Strand: Direct

Name: rpe [H]

Synonym: APH_0002

Alternate gene names: 88607073

Gene position: 2838-3548 (Clockwise)

Preceding gene: 88607943

Following gene: 88607911

Centisome position: 0.19

GC content: 42.33

Gene sequence:

>711_bases
TTGTTAGCTAAAAAGGAAGACTTTCACACCTTTGGTAATGGTGTTGGCTCTGCTGGAACAGGTGGAGTTGTAGTTTCTGC
ATCCATGTTGTCTGCGGATTTTTCAAATCTTAGAGAAGAGATAGCAGCGGTTAGTACGGCTGGTGCAGATTGGTTACACA
TTGATGTGATGGATGGGTGCTTCGTCCCCAGTTTGACTATGGGTCCTGTGGTGATTTCCGGCATTAGGAAATGTACAAAT
ATGTTTCTTGATGTGCATTTGATGATTAATCGCCCAGGCGATCATCTGAAGAGTGTGGTAGATGCTGGAGCTGATATGAT
TACAGTGCATGCTGAGTCAGAAGTGCATCTATGCAGGTTAATAAAGCAAATTAAGCTTTATGGTAAAAAAGTTGGGGTAT
CCATAGTTCCAAAGACTCACCACAGCGTCTTAGAGTACATTATACATGATTTAGATGTGGTATTGGTAATGTCAGTTGAT
CCTGGTTTTGGAGGACAGGCGTTTTTGGAACCACAGTTAAAAAAGATAGAGCACATTCGCAAGATGATAGAGGAAAGCTC
ATCAACCGCGAAAATCGCTGTTGATGGTGGTGTTTCAACGGATAATGCCCGGGCTGTTATCGAGGCAGGTGCGAATATAC
TCGTTGTTGGAACGGCGCTGTTTGCTGCTGACGATATGAGTAAAGTTGTAAGAACTTTAAAATCATTTTAA

Upstream 100 bases:

>100_bases
TAAATGCGTATGCACAATTTTGGCGTTTTACCTGTTGCAGCTTGAAAGCCTCTTGTTCTGCCTATATAATACGTGAATTC
TTGTTTGGTGACTGGTTACA

Downstream 100 bases:

>100_bases
AGGAAGTAACTTATGAGGATGGAATTGTGTAAGAACATTCCCCTATTTTTTTTTGCTGCTGTGGGCAGGTATTTTGTGGG
ACTGCTCATCCCTGTAGGCA

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MLAKKEDFHTFGNGVGSAGTGGVVVSASMLSADFSNLREEIAAVSTAGADWLHIDVMDGCFVPSLTMGPVVISGIRKCTN
MFLDVHLMINRPGDHLKSVVDAGADMITVHAESEVHLCRLIKQIKLYGKKVGVSIVPKTHHSVLEYIIHDLDVVLVMSVD
PGFGGQAFLEPQLKKIEHIRKMIEESSSTAKIAVDGGVSTDNARAVIEAGANILVVGTALFAADDMSKVVRTLKSF

Sequences:

>Translated_236_residues
MLAKKEDFHTFGNGVGSAGTGGVVVSASMLSADFSNLREEIAAVSTAGADWLHIDVMDGCFVPSLTMGPVVISGIRKCTN
MFLDVHLMINRPGDHLKSVVDAGADMITVHAESEVHLCRLIKQIKLYGKKVGVSIVPKTHHSVLEYIIHDLDVVLVMSVD
PGFGGQAFLEPQLKKIEHIRKMIEESSSTAKIAVDGGVSTDNARAVIEAGANILVVGTALFAADDMSKVVRTLKSF
>Mature_236_residues
MLAKKEDFHTFGNGVGSAGTGGVVVSASMLSADFSNLREEIAAVSTAGADWLHIDVMDGCFVPSLTMGPVVISGIRKCTN
MFLDVHLMINRPGDHLKSVVDAGADMITVHAESEVHLCRLIKQIKLYGKKVGVSIVPKTHHSVLEYIIHDLDVVLVMSVD
PGFGGQAFLEPQLKKIEHIRKMIEESSSTAKIAVDGGVSTDNARAVIEAGANILVVGTALFAADDMSKVVRTLKSF

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=216, Percent_Identity=37.962962962963, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI219879828, Length=216, Percent_Identity=36.1111111111111, Blast_Score=142, Evalue=2e-34,
Organism=Homo sapiens, GI24307923, Length=169, Percent_Identity=32.5443786982249, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI1789788, Length=214, Percent_Identity=41.588785046729, Blast_Score=167, Evalue=4e-43,
Organism=Escherichia coli, GI1790523, Length=196, Percent_Identity=37.2448979591837, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790754, Length=203, Percent_Identity=27.0935960591133, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17552948, Length=217, Percent_Identity=41.0138248847926, Blast_Score=156, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6322341, Length=225, Percent_Identity=37.3333333333333, Blast_Score=150, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24586301, Length=211, Percent_Identity=40.2843601895735, Blast_Score=158, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 25184; Mature: 25184

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAKKEDFHTFGNGVGSAGTGGVVVSASMLSADFSNLREEIAAVSTAGADWLHIDVMDGC
CCCCCCCHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
FVPSLTMGPVVISGIRKCTNMFLDVHLMINRPGDHLKSVVDAGADMITVHAESEVHLCRL
CCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHCCCCEEEEECCCCHHHHHH
IKQIKLYGKKVGVSIVPKTHHSVLEYIIHDLDVVLVMSVDPGFGGQAFLEPQLKKIEHIR
HHHHHHHHHHCCEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHCCHHHHHHHHHH
KMIEESSSTAKIAVDGGVSTDNARAVIEAGANILVVGTALFAADDMSKVVRTLKSF
HHHHCCCCCEEEEECCCCCCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLAKKEDFHTFGNGVGSAGTGGVVVSASMLSADFSNLREEIAAVSTAGADWLHIDVMDGC
CCCCCCCHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
FVPSLTMGPVVISGIRKCTNMFLDVHLMINRPGDHLKSVVDAGADMITVHAESEVHLCRL
CCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHCCCCEEEEECCCCHHHHHH
IKQIKLYGKKVGVSIVPKTHHSVLEYIIHDLDVVLVMSVDPGFGGQAFLEPQLKKIEHIR
HHHHHHHHHHCCEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHCCHHHHHHHHHH
KMIEESSSTAKIAVDGGVSTDNARAVIEAGANILVVGTALFAADDMSKVVRTLKSF
HHHHCCCCCEEEEECCCCCCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231; 9298645 [H]