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The map label for this gene is acpS

Identifier: 88606943

GI number: 88606943

Start: 669495

End: 669863

Strand: Reverse

Name: acpS

Synonym: APH_0646

Alternate gene names: 88606943

Gene position: 669863-669495 (Counterclockwise)

Preceding gene: 88607069

Following gene: 88607230

Centisome position: 45.53

GC content: 42.82

Gene sequence:

>369_bases
ATGATACTGGGCATAGGTGTAGATTTAGTATGCACGAGAAGGATACAAGCTTTAATTGCGAAGTATGGGAACAAGTTCAC
CAATAGAATATTTTCTGAGAAAGAAATACTGGATTCTCTGAAGTATCGGGATGAGTATGCTCGTGCAAGACATTTTGCCA
AGAGGTTTGCTGCTAAGGAAGCGTATGTAAAGGCGCTAGGTTTGGGTTTTGGTCGCGGAGTAGAGGCTAAGGATATATCT
GTGCATAACGATCCTTATGGCCAGCCCATGATTTCACTTGAGGGCGGTGCTCTGCGCAATGGTCATGTAAAGCTTTCTAT
GAGCGATGATGGTGATTATGCAATAGCCTTCGTTACATTACATACTTAG

Upstream 100 bases:

>100_bases
GAAACTCCTTTATCAAGGATGGTGTATTAGAGTTAAAAAATCGTGCAACTGGTGATATAGAGCTCCTTTCTGTTGATGAT
GTAGTTTCTAGGATTAGCGT

Downstream 100 bases:

>100_bases
TTTTGGTACAAAATTAAGAAGCAAAGTCGTTATCTGTGAAGCGCCGGTATAGAAAGTAAAAAACATAGGCGATAATACGA
GTAAAAAACGAAGGCGCTGC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MILGIGVDLVCTRRIQALIAKYGNKFTNRIFSEKEILDSLKYRDEYARARHFAKRFAAKEAYVKALGLGFGRGVEAKDIS
VHNDPYGQPMISLEGGALRNGHVKLSMSDDGDYAIAFVTLHT

Sequences:

>Translated_122_residues
MILGIGVDLVCTRRIQALIAKYGNKFTNRIFSEKEILDSLKYRDEYARARHFAKRFAAKEAYVKALGLGFGRGVEAKDIS
VHNDPYGQPMISLEGGALRNGHVKLSMSDDGDYAIAFVTLHT
>Mature_122_residues
MILGIGVDLVCTRRIQALIAKYGNKFTNRIFSEKEILDSLKYRDEYARARHFAKRFAAKEAYVKALGLGFGRGVEAKDIS
VHNDPYGQPMISLEGGALRNGHVKLSMSDDGDYAIAFVTLHT

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=129, Percent_Identity=35.6589147286822, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_ANAPZ (Q2GK71)

Other databases:

- EMBL:   CP000235
- RefSeq:   YP_505230.1
- ProteinModelPortal:   Q2GK71
- SMR:   Q2GK71
- STRING:   Q2GK71
- GeneID:   3930378
- GenomeReviews:   CP000235_GR
- KEGG:   aph:APH_0646
- NMPDR:   fig|212042.5.peg.631
- TIGR:   APH_0646
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- PhylomeDB:   Q2GK71
- ProtClustDB:   PRK14659
- BioCyc:   APHA212042:APH_0646-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13580; Mature: 13580

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILGIGVDLVCTRRIQALIAKYGNKFTNRIFSEKEILDSLKYRDEYARARHFAKRFAAKE
CEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYVKALGLGFGRGVEAKDISVHNDPYGQPMISLEGGALRNGHVKLSMSDDGDYAIAFVTL
HHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEECCCEEECCEEEEEECCCCCEEEEEEEE
HT
EC
>Mature Secondary Structure
MILGIGVDLVCTRRIQALIAKYGNKFTNRIFSEKEILDSLKYRDEYARARHFAKRFAAKE
CEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYVKALGLGFGRGVEAKDISVHNDPYGQPMISLEGGALRNGHVKLSMSDDGDYAIAFVTL
HHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEECCCEEECCEEEEEECCCCCEEEEEEEE
HT
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA