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The map label for this gene is dcd

Identifier: 88606935

GI number: 88606935

Start: 134999

End: 135556

Strand: Reverse

Name: dcd

Synonym: APH_0130

Alternate gene names: 88606935

Gene position: 135556-134999 (Counterclockwise)

Preceding gene: 88607217

Following gene: 88607023

Centisome position: 9.21

GC content: 45.16

Gene sequence:

>558_bases
ATGTCAGTCATGCCTGATCACTGGATCAAGGAAAGGGCCCTAAAAGATGGTATGATCTCCCCGTTCGTAGACCACAAAGA
AGGCACGGGTGTTTTGTCGTATGGTTTGTCTTCCTATGGCTATGATGCTCGGCTGGATAATAAGTTCAAGATTTTTGCCA
ATACACACTCAGTGGTAGTGGATCCTAAGAACTTTTCGCAAGATAGCTTTGTTGATCGTGAAGGAGATTTCTGCATCATT
CCACCAAACAGCTTTATGCTAGCCAAGACTGTAGAGTACTTTAACATCCCACGAGACGTTATGGTTGTTTGTGTTGGAAA
GTCAACATACGCTCGCTGTGGCATCGTAGTTAATGTGACGCCTCTTGAACCAGGGTGGTCAGGCTACGTAACTCTGGAAT
TCTCTAATACATCTCCGTTACCTGTGAAGGTATATGCGTTTGAGGGCGCATGCCAGTTCCTCTTTTTTTCAGGCAAGGAA
CGTTGCAGCAAGTCTTACGACGAAGCTGGGGGCAAGTATATGGGGCAAAGTGACGTAACATTGCCAATTATTAGTTAG

Upstream 100 bases:

>100_bases
TTCCTCATGCGTACTGTGAGAGTTTCTACTTGAAGGAATGTAAAATTGGGTATAGAGTTGGAGGTTAGTTTGTTCTTTAT
TATTGCATAGGGGTTTGCTT

Downstream 100 bases:

>100_bases
AGAACTTTGTAATTTACCGTCATCGATCCTTAATGCGCGCAGTTTTGCTGTGGCTTCAACAGGTGGTAATATATCGAATT
TTAGAATAGATAGCGCGGGA

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSVMPDHWIKERALKDGMISPFVDHKEGTGVLSYGLSSYGYDARLDNKFKIFANTHSVVVDPKNFSQDSFVDREGDFCII
PPNSFMLAKTVEYFNIPRDVMVVCVGKSTYARCGIVVNVTPLEPGWSGYVTLEFSNTSPLPVKVYAFEGACQFLFFSGKE
RCSKSYDEAGGKYMGQSDVTLPIIS

Sequences:

>Translated_185_residues
MSVMPDHWIKERALKDGMISPFVDHKEGTGVLSYGLSSYGYDARLDNKFKIFANTHSVVVDPKNFSQDSFVDREGDFCII
PPNSFMLAKTVEYFNIPRDVMVVCVGKSTYARCGIVVNVTPLEPGWSGYVTLEFSNTSPLPVKVYAFEGACQFLFFSGKE
RCSKSYDEAGGKYMGQSDVTLPIIS
>Mature_184_residues
SVMPDHWIKERALKDGMISPFVDHKEGTGVLSYGLSSYGYDARLDNKFKIFANTHSVVVDPKNFSQDSFVDREGDFCIIP
PNSFMLAKTVEYFNIPRDVMVVCVGKSTYARCGIVVNVTPLEPGWSGYVTLEFSNTSPLPVKVYAFEGACQFLFFSGKER
CSKSYDEAGGKYMGQSDVTLPIIS

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

Organism=Escherichia coli, GI1788379, Length=132, Percent_Identity=34.0909090909091, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_ANAPZ (Q2GLJ4)

Other databases:

- EMBL:   CP000235
- RefSeq:   YP_504757.1
- PDB:   3KM3
- PDBsum:   3KM3
- ProteinModelPortal:   Q2GLJ4
- SMR:   Q2GLJ4
- STRING:   Q2GLJ4
- GeneID:   3930370
- GenomeReviews:   CP000235_GR
- KEGG:   aph:APH_0130
- NMPDR:   fig|212042.5.peg.125
- TIGR:   APH_0130
- eggNOG:   COG0717
- HOGENOM:   HBG553199
- OMA:   MEYFRIP
- PhylomeDB:   Q2GLJ4
- ProtClustDB:   PRK00416
- BioCyc:   APHA212042:APH_0130-MONOMER
- HAMAP:   MF_00146
- InterPro:   IPR011962
- TIGRFAMs:   TIGR02274

Pfam domain/function: NA

EC number: =3.5.4.13

Molecular weight: Translated: 20591; Mature: 20459

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVMPDHWIKERALKDGMISPFVDHKEGTGVLSYGLSSYGYDARLDNKFKIFANTHSVVV
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCEECCEEEEEECCCEEEE
DPKNFSQDSFVDREGDFCIIPPNSFMLAKTVEYFNIPRDVMVVCVGKSTYARCGIVVNVT
CCCCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHCCCCHHEEEEECCCCCCEEEEEEEEE
PLEPGWSGYVTLEFSNTSPLPVKVYAFEGACQFLFFSGKERCSKSYDEAGGKYMGQSDVT
ECCCCCCEEEEEEECCCCCCEEEEEEECCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCE
LPIIS
EEEEC
>Mature Secondary Structure 
SVMPDHWIKERALKDGMISPFVDHKEGTGVLSYGLSSYGYDARLDNKFKIFANTHSVVV
CCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCEECCEEEEEECCCEEEE
DPKNFSQDSFVDREGDFCIIPPNSFMLAKTVEYFNIPRDVMVVCVGKSTYARCGIVVNVT
CCCCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHCCCCHHEEEEECCCCCCEEEEEEEEE
PLEPGWSGYVTLEFSNTSPLPVKVYAFEGACQFLFFSGKERCSKSYDEAGGKYMGQSDVT
ECCCCCCEEEEEEECCCCCCEEEEEEECCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCE
LPIIS
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA