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The map label for this gene is gpmI

Identifier: 88606919

GI number: 88606919

Start: 401407

End: 402897

Strand: Direct

Name: gpmI

Synonym: APH_0389

Alternate gene names: 88606919

Gene position: 401407-402897 (Clockwise)

Preceding gene: 88607334

Following gene: 88607190

Centisome position: 27.28

GC content: 44.94

Gene sequence:

>1491_bases
ATGTCTGGGAGCAACGTAGTACTCTGTATACTTGACGGATGGGGTAATGGTAGTGGTGGTCGTTATGATGCTATTCATGC
GGCGTATACGCCATTCTGGGACACTGCGGTTTCATGCTGTCCTATGAGTAGTTTGTCTGCTAGTGGAACGGATGTCGGAT
TGCCTTCAGGTCAGGTCGGGAATTCAGAAGTAGGGCACATAAGTATAGGATGCGGCAGGATAGTGCTTCAGGATCTGTTG
AGAATTAATCTTGAGATTAATGAGGTTCACAAGAATCCTAAATTGTTGGACTTTGTGCGCGATATACAGGCGAAGGGTGG
GGTATGCCACATGATTGGTCTGCTTTCTGATGGTGGAGTGCATTCTCTTCAGGCGCACATGGAAACCATTATTGAGGTTA
TCACCGGATTTGGCATCAAGGTTTTTATACATGTAATTCTAGATGGTAGGGATGTTCCACCGCGTTCTGCTGAGAAGTAT
ATCGGTATGCTGAACGCTAAAATTGAGCACTTAAATGCCGAAATTGCTACTGTTGCAGGGCGTTACTATGCTATGGATAG
GGATAATCGCCTGGATAGGACATGTAAAGCTTATGATGCAATAGCGTATGCTACAGGGCCGAGAAGCGGCAGTGCAATGG
AGGCTTTAGAAAAAAGCTACAATAGTGGAGTTACTGATGAGTTTATGGTACCTACGGTCATAGGCGATTATGATGGTATG
GGTGCGGAGGATGGTGTATTATTCACTAACTTCCGGAATGACCGTGTCTTGCAATTGCTAGGTATGTTGTTGCATAGGTT
TCCAGAGGTCAGTAACGTGCTGGGTATGCGGCAGTACTCGGAGAAGATGCGTATTGCTAGTCTATTTCCTCCTAGAGAGA
TACATAGAAGTTTAGGTGAGGTTATTTCCGAGCGCGGGCTTAAGCAGCTGCGTATTGCTGAAACTGAGAAGTTTGCTCAC
GTAACGTTCTTTTTTAACGGGGGTAGGGAAGAGCCTTTTACAGGGGAAGATAGGATAATAATACCGTCGCCTGATGTTAG
TACGTATGACTTGAAGCCTGAAATGTCAGCTGTGGAGATAACTGATTCGTTGGTAGAGCGCATAAATTCTCAGCAATATG
CATTGACGGTGGTTAATTATGCAAACGCTGACATGGTTGGGCATACCGGTAATATGGAAGCAGCTAAAAAAGCGGTTACT
ACTGTAGATAGTTGCTTACAGAGGGTGTTTTATGCTGCAGTAAACGCGGGAGCTGTTATGCTGATAACTGCTGACCATGG
AAATGCTGAGAAGATGTTTGATGTGCAAAATGATTCACCATTTACTGCACATACATCAAGTATGGTTCCGTTTGTGGTAT
GCAACGCTGATGGTGATATAAGCTTGTCGGATGGTAGGCTGTGTGATGTTGCTCCGACCGTTCTCGATCTTATGAATATA
CCTCAGCCTAGTGATATGACAGGGTGCTCCTTGATCACCAGAAATAGCTAG

Upstream 100 bases:

>100_bases
CGTATTATTTTTATGAATTATTTCGAGTATATACGATAGTTGTTTACTACCATAAATCACATAGGTAAAATCGCACTTTC
ATTGAGCAACGCGGTAGCGT

Downstream 100 bases:

>100_bases
TTATACCGAGGGATTGCAATCCAAATTGCGTATTGTGAGGGCCTGTTGTTGCGAAGTTATAGGACATGTAGCTTGAAACC
GCCGATAAGATTGCCAGATT

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MSGSNVVLCILDGWGNGSGGRYDAIHAAYTPFWDTAVSCCPMSSLSASGTDVGLPSGQVGNSEVGHISIGCGRIVLQDLL
RINLEINEVHKNPKLLDFVRDIQAKGGVCHMIGLLSDGGVHSLQAHMETIIEVITGFGIKVFIHVILDGRDVPPRSAEKY
IGMLNAKIEHLNAEIATVAGRYYAMDRDNRLDRTCKAYDAIAYATGPRSGSAMEALEKSYNSGVTDEFMVPTVIGDYDGM
GAEDGVLFTNFRNDRVLQLLGMLLHRFPEVSNVLGMRQYSEKMRIASLFPPREIHRSLGEVISERGLKQLRIAETEKFAH
VTFFFNGGREEPFTGEDRIIIPSPDVSTYDLKPEMSAVEITDSLVERINSQQYALTVVNYANADMVGHTGNMEAAKKAVT
TVDSCLQRVFYAAVNAGAVMLITADHGNAEKMFDVQNDSPFTAHTSSMVPFVVCNADGDISLSDGRLCDVAPTVLDLMNI
PQPSDMTGCSLITRNS

Sequences:

>Translated_496_residues
MSGSNVVLCILDGWGNGSGGRYDAIHAAYTPFWDTAVSCCPMSSLSASGTDVGLPSGQVGNSEVGHISIGCGRIVLQDLL
RINLEINEVHKNPKLLDFVRDIQAKGGVCHMIGLLSDGGVHSLQAHMETIIEVITGFGIKVFIHVILDGRDVPPRSAEKY
IGMLNAKIEHLNAEIATVAGRYYAMDRDNRLDRTCKAYDAIAYATGPRSGSAMEALEKSYNSGVTDEFMVPTVIGDYDGM
GAEDGVLFTNFRNDRVLQLLGMLLHRFPEVSNVLGMRQYSEKMRIASLFPPREIHRSLGEVISERGLKQLRIAETEKFAH
VTFFFNGGREEPFTGEDRIIIPSPDVSTYDLKPEMSAVEITDSLVERINSQQYALTVVNYANADMVGHTGNMEAAKKAVT
TVDSCLQRVFYAAVNAGAVMLITADHGNAEKMFDVQNDSPFTAHTSSMVPFVVCNADGDISLSDGRLCDVAPTVLDLMNI
PQPSDMTGCSLITRNS
>Mature_495_residues
SGSNVVLCILDGWGNGSGGRYDAIHAAYTPFWDTAVSCCPMSSLSASGTDVGLPSGQVGNSEVGHISIGCGRIVLQDLLR
INLEINEVHKNPKLLDFVRDIQAKGGVCHMIGLLSDGGVHSLQAHMETIIEVITGFGIKVFIHVILDGRDVPPRSAEKYI
GMLNAKIEHLNAEIATVAGRYYAMDRDNRLDRTCKAYDAIAYATGPRSGSAMEALEKSYNSGVTDEFMVPTVIGDYDGMG
AEDGVLFTNFRNDRVLQLLGMLLHRFPEVSNVLGMRQYSEKMRIASLFPPREIHRSLGEVISERGLKQLRIAETEKFAHV
TFFFNGGREEPFTGEDRIIIPSPDVSTYDLKPEMSAVEITDSLVERINSQQYALTVVNYANADMVGHTGNMEAAKKAVTT
VDSCLQRVFYAAVNAGAVMLITADHGNAEKMFDVQNDSPFTAHTSSMVPFVVCNADGDISLSDGRLCDVAPTVLDLMNIP
QPSDMTGCSLITRNS

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=510, Percent_Identity=43.3333333333333, Blast_Score=396, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI32564249, Length=515, Percent_Identity=40, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17507741, Length=515, Percent_Identity=40, Blast_Score=361, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_ANAPZ (Q2GKV7)

Other databases:

- EMBL:   CP000235
- RefSeq:   YP_504994.1
- ProteinModelPortal:   Q2GKV7
- SMR:   Q2GKV7
- STRING:   Q2GKV7
- GeneID:   3930060
- GenomeReviews:   CP000235_GR
- KEGG:   aph:APH_0389
- NMPDR:   fig|212042.5.peg.374
- TIGR:   APH_0389
- eggNOG:   COG0696
- HOGENOM:   HBG613255
- OMA:   DHGNAEL
- PhylomeDB:   Q2GKV7
- ProtClustDB:   PRK05434
- BioCyc:   APHA212042:APH_0389-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 53945; Mature: 53814

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: ACT_SITE 62-62

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSNVVLCILDGWGNGSGGRYDAIHAAYTPFWDTAVSCCPMSSLSASGTDVGLPSGQVG
CCCCCEEEEEEECCCCCCCCCEEEEHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
NSEVGHISIGCGRIVLQDLLRINLEINEVHKNPKLLDFVRDIQAKGGVCHMIGLLSDGGV
CCCCCEEEECHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCH
HSLQAHMETIIEVITGFGIKVFIHVILDGRDVPPRSAEKYIGMLNAKIEHLNAEIATVAG
HHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCC
RYYAMDRDNRLDRTCKAYDAIAYATGPRSGSAMEALEKSYNSGVTDEFMVPTVIGDYDGM
EEEEECCCCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCCCCCEECCEEECCCCCC
GAEDGVLFTNFRNDRVLQLLGMLLHRFPEVSNVLGMRQYSEKMRIASLFPPREIHRSLGE
CCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VISERGLKQLRIAETEKFAHVTFFFNGGREEPFTGEDRIIIPSPDVSTYDLKPEMSAVEI
HHHHCCHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCEEEECCCCCCEEECCCCCHHHHH
TDSLVERINSQQYALTVVNYANADMVGHTGNMEAAKKAVTTVDSCLQRVFYAAVNAGAVM
HHHHHHHHCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LITADHGNAEKMFDVQNDSPFTAHTSSMVPFVVCNADGDISLSDGRLCDVAPTVLDLMNI
EEEECCCCCCCEEEECCCCCCEEECCCCCEEEEECCCCCEEECCCCEEHHHHHHHHHHCC
PQPSDMTGCSLITRNS
CCCCCCCCCEEEECCC
>Mature Secondary Structure 
SGSNVVLCILDGWGNGSGGRYDAIHAAYTPFWDTAVSCCPMSSLSASGTDVGLPSGQVG
CCCCEEEEEEECCCCCCCCCEEEEHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
NSEVGHISIGCGRIVLQDLLRINLEINEVHKNPKLLDFVRDIQAKGGVCHMIGLLSDGGV
CCCCCEEEECHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCH
HSLQAHMETIIEVITGFGIKVFIHVILDGRDVPPRSAEKYIGMLNAKIEHLNAEIATVAG
HHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCC
RYYAMDRDNRLDRTCKAYDAIAYATGPRSGSAMEALEKSYNSGVTDEFMVPTVIGDYDGM
EEEEECCCCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCCCCCEECCEEECCCCCC
GAEDGVLFTNFRNDRVLQLLGMLLHRFPEVSNVLGMRQYSEKMRIASLFPPREIHRSLGE
CCCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VISERGLKQLRIAETEKFAHVTFFFNGGREEPFTGEDRIIIPSPDVSTYDLKPEMSAVEI
HHHHCCHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCEEEECCCCCCEEECCCCCHHHHH
TDSLVERINSQQYALTVVNYANADMVGHTGNMEAAKKAVTTVDSCLQRVFYAAVNAGAVM
HHHHHHHHCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LITADHGNAEKMFDVQNDSPFTAHTSSMVPFVVCNADGDISLSDGRLCDVAPTVLDLMNI
EEEECCCCCCCEEEECCCCCCEEECCCCCEEEEECCCCCEEECCCCEEHHHHHHHHHHCC
PQPSDMTGCSLITRNS
CCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA