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The map label for this gene is adiC [H]

Identifier: 87199691

GI number: 87199691

Start: 1755648

End: 1756964

Strand: Reverse

Name: adiC [H]

Synonym: Saro_1674

Alternate gene names: 87199691

Gene position: 1756964-1755648 (Counterclockwise)

Preceding gene: 87199694

Following gene: 87199688

Centisome position: 49.33

GC content: 67.43

Gene sequence:

>1317_bases
ATGAACAAGGTTCGTGGAAGCAAGGTTCGCGGCCTGGGGTTCTGGATGACGCTGGCGCTGGTCGTGGGCAACATGATCGG
CTCGGGCATCTACATCCTTCCCGCGACGCTGGCGCCGTTGGGGTTCAACCAGTTGATCGGCTGGGCAGTCACTCTTGCCG
GGGCGCTGTGCCTTGCGGCTGCCTTTGCAAGAATGGGAGCAAGGTTGCCGCTGGCGGGCGGGCCCTATGCCTATGCCCAG
GCCGCATTCGGACCGATCCCGGGCTTCGTGACGGCATGGTCGTACTGGACCATGCTGTGGGCGGGCAATGGCGCGGTCGC
GGTAGCGCTGGTCAGCAACCTCAGCCTGATCGCGCCCTGGATCGGCGCGACGCCAGCCGTCCCCGCGCTGCTTTCAGTCG
GTTTCGTGTGGCTGCTGACGCTGGTCAACATTCGCGGCGTGCGCGCGGCGGGGGACGTGTCGGTGGTGACGACCGCGCTG
AAGCTCGTGCCGCTGGCCGGGCTGATAGGCCTGGCGATCTGGCTGCTGATCACGGGCGCGCCAACGGTGGTCCAGCCCGA
GGTCCCGTTGTCGGGCGGGGTGATCGCCACCGCCGCGGGACTTACCTTCTGGGGCTTCCTCGGCCTTGAATCCGCCACCG
TCCCCGCCGACAAGGTGGAGAATGCGCGGACAGTGGTGCCGCGCGCGACGCTGATCGGCGTTGCAATCACCGGCCTCGTC
TACATGGGCATTTCAGGCGCCTTCGCGCTCTACATGCCAATGGCGGATGCTGCCGCCTCCCCTGCCCCGGTGGCCGATTT
CCTCGCACGCTTCTTCGGCTCGGGCATGGGCCAGGTCGTCGCCCTATTCGCCGCGATCAGCGCGTTCGGCACGCTGAACG
GCTTCATCCTGCTGCAAGGCGAAGTGCCGTGGGCCATGGCGCGCGGCGGCGTCTTTCCCCGGTGGTTCGCCGCCGAAGGC
CCGCGCGGTACGCCGGTGCGGTCGCACGTGGTGTCGAGCATACTGCTGAGTATCGTGACCCTGCTCAACTACGGGCGCGG
GATGGGCGACCTGTTCGCCTTCATCGCCTCGGTCAGCCTCGCCGCAGGGATGCTGTCCTATTTCGTCGCGATGCTCGCAG
CCGTGCGCCTGCTACCCGACGAGCGCCCGATGGTGATCGCGGCACTCGTCGGTGCGGCATTCATCGCATGGGCGGCGTGG
GGACTTGGCGCGGAGGCGCTGACCTATGGGGCAGGCTTCGTCGCGCTAGGCCTGCCCGTGTACCTCTGGATCAGGCGCGA
TGGAGCAGCTTCCACAACAGCGAACGATCCCGGATGA

Upstream 100 bases:

>100_bases
ACGCCTCGCGATCAAGCGTTAGTCTGCGCACGATGCACAGGACCGATCGCGCCGAACCACTTCAAATGGACGGGCGACCA
TGCAGCAGGGAAGCGGCGCA

Downstream 100 bases:

>100_bases
TCTCATGCGCCGCATTGTGCCCCGGCGCGCCGGTCACGCCGCCGCCGGGATGCGTGCCCGAGCCGCACATGTAGAGCCCC
TTGATCGGCGAGCGATAGTC

Product: phospholipid binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MNKVRGSKVRGLGFWMTLALVVGNMIGSGIYILPATLAPLGFNQLIGWAVTLAGALCLAAAFARMGARLPLAGGPYAYAQ
AAFGPIPGFVTAWSYWTMLWAGNGAVAVALVSNLSLIAPWIGATPAVPALLSVGFVWLLTLVNIRGVRAAGDVSVVTTAL
KLVPLAGLIGLAIWLLITGAPTVVQPEVPLSGGVIATAAGLTFWGFLGLESATVPADKVENARTVVPRATLIGVAITGLV
YMGISGAFALYMPMADAAASPAPVADFLARFFGSGMGQVVALFAAISAFGTLNGFILLQGEVPWAMARGGVFPRWFAAEG
PRGTPVRSHVVSSILLSIVTLLNYGRGMGDLFAFIASVSLAAGMLSYFVAMLAAVRLLPDERPMVIAALVGAAFIAWAAW
GLGAEALTYGAGFVALGLPVYLWIRRDGAASTTANDPG

Sequences:

>Translated_438_residues
MNKVRGSKVRGLGFWMTLALVVGNMIGSGIYILPATLAPLGFNQLIGWAVTLAGALCLAAAFARMGARLPLAGGPYAYAQ
AAFGPIPGFVTAWSYWTMLWAGNGAVAVALVSNLSLIAPWIGATPAVPALLSVGFVWLLTLVNIRGVRAAGDVSVVTTAL
KLVPLAGLIGLAIWLLITGAPTVVQPEVPLSGGVIATAAGLTFWGFLGLESATVPADKVENARTVVPRATLIGVAITGLV
YMGISGAFALYMPMADAAASPAPVADFLARFFGSGMGQVVALFAAISAFGTLNGFILLQGEVPWAMARGGVFPRWFAAEG
PRGTPVRSHVVSSILLSIVTLLNYGRGMGDLFAFIASVSLAAGMLSYFVAMLAAVRLLPDERPMVIAALVGAAFIAWAAW
GLGAEALTYGAGFVALGLPVYLWIRRDGAASTTANDPG
>Mature_438_residues
MNKVRGSKVRGLGFWMTLALVVGNMIGSGIYILPATLAPLGFNQLIGWAVTLAGALCLAAAFARMGARLPLAGGPYAYAQ
AAFGPIPGFVTAWSYWTMLWAGNGAVAVALVSNLSLIAPWIGATPAVPALLSVGFVWLLTLVNIRGVRAAGDVSVVTTAL
KLVPLAGLIGLAIWLLITGAPTVVQPEVPLSGGVIATAAGLTFWGFLGLESATVPADKVENARTVVPRATLIGVAITGLV
YMGISGAFALYMPMADAAASPAPVADFLARFFGSGMGQVVALFAAISAFGTLNGFILLQGEVPWAMARGGVFPRWFAAEG
PRGTPVRSHVVSSILLSIVTLLNYGRGMGDLFAFIASVSLAAGMLSYFVAMLAAVRLLPDERPMVIAALVGAAFIAWAAW
GLGAEALTYGAGFVALGLPVYLWIRRDGAASTTANDPG

Specific function: Major component of the acid-resistance (AR) system allowing enteric pathogens to survive the acidic environment in the stomach. Exchanges extracellular arginine for its intracellular decarboxylation product agmatine (Agm) thereby expelling intracellular p

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI186910308, Length=348, Percent_Identity=27.2988505747126, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI186910306, Length=348, Percent_Identity=27.2988505747126, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI186910304, Length=348, Percent_Identity=27.2988505747126, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI9790235, Length=397, Percent_Identity=25.9445843828715, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI33286428, Length=445, Percent_Identity=27.1910112359551, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI115648063, Length=365, Percent_Identity=25.4794520547945, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI115648022, Length=365, Percent_Identity=25.4794520547945, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI187423910, Length=315, Percent_Identity=25.7142857142857, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI7657591, Length=315, Percent_Identity=25.7142857142857, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI71979932, Length=452, Percent_Identity=26.7699115044248, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI2367353, Length=395, Percent_Identity=33.9240506329114, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1786908, Length=429, Percent_Identity=28.4382284382284, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790575, Length=440, Percent_Identity=27.5, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1787890, Length=452, Percent_Identity=26.7699115044248, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87082250, Length=333, Percent_Identity=26.1261261261261, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786302, Length=350, Percent_Identity=22.8571428571429, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081869, Length=406, Percent_Identity=23.6453201970443, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786789, Length=386, Percent_Identity=22.5388601036269, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1786694, Length=452, Percent_Identity=24.7787610619469, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790584, Length=386, Percent_Identity=23.8341968911917, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI87082023, Length=280, Percent_Identity=24.2857142857143, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI32566699, Length=408, Percent_Identity=25.4901960784314, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71995388, Length=352, Percent_Identity=24.1477272727273, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71995382, Length=352, Percent_Identity=24.1477272727273, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71993915, Length=365, Percent_Identity=23.8356164383562, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531343, Length=363, Percent_Identity=24.2424242424242, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI221331183, Length=321, Percent_Identity=27.4143302180685, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI17647653, Length=321, Percent_Identity=27.4143302180685, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24664379, Length=321, Percent_Identity=27.4143302180685, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24651635, Length=434, Percent_Identity=26.9585253456221, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24651633, Length=434, Percent_Identity=26.9585253456221, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641995, Length=370, Percent_Identity=26.2162162162162, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641993, Length=370, Percent_Identity=26.2162162162162, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45550968, Length=365, Percent_Identity=26.3013698630137, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19921172, Length=365, Percent_Identity=26.3013698630137, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357367, Length=415, Percent_Identity=23.6144578313253, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 45037; Mature: 45037

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVRGSKVRGLGFWMTLALVVGNMIGSGIYILPATLAPLGFNQLIGWAVTLAGALCLAA
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHH
AFARMGARLPLAGGPYAYAQAAFGPIPGFVTAWSYWTMLWAGNGAVAVALVSNLSLIAPW
HHHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHEEECCCCEEHHHHHCCHHHHHH
IGATPAVPALLSVGFVWLLTLVNIRGVRAAGDVSVVTTALKLVPLAGLIGLAIWLLITGA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTVVQPEVPLSGGVIATAAGLTFWGFLGLESATVPADKVENARTVVPRATLIGVAITGLV
CCEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHCCHHHHHHHHHHHHH
YMGISGAFALYMPMADAAASPAPVADFLARFFGSGMGQVVALFAAISAFGTLNGFILLQG
HHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEC
EVPWAMARGGVFPRWFAAEGPRGTPVRSHVVSSILLSIVTLLNYGRGMGDLFAFIASVSL
CCCHHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AAGMLSYFVAMLAAVRLLPDERPMVIAALVGAAFIAWAAWGLGAEALTYGAGFVALGLPV
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHCCEE
YLWIRRDGAASTTANDPG
EEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MNKVRGSKVRGLGFWMTLALVVGNMIGSGIYILPATLAPLGFNQLIGWAVTLAGALCLAA
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHH
AFARMGARLPLAGGPYAYAQAAFGPIPGFVTAWSYWTMLWAGNGAVAVALVSNLSLIAPW
HHHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHEEECCCCEEHHHHHCCHHHHHH
IGATPAVPALLSVGFVWLLTLVNIRGVRAAGDVSVVTTALKLVPLAGLIGLAIWLLITGA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTVVQPEVPLSGGVIATAAGLTFWGFLGLESATVPADKVENARTVVPRATLIGVAITGLV
CCEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHCCHHHHHHHHHHHHH
YMGISGAFALYMPMADAAASPAPVADFLARFFGSGMGQVVALFAAISAFGTLNGFILLQG
HHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEC
EVPWAMARGGVFPRWFAAEGPRGTPVRSHVVSSILLSIVTLLNYGRGMGDLFAFIASVSL
CCCHHHHCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AAGMLSYFVAMLAAVRLLPDERPMVIAALVGAAFIAWAAWGLGAEALTYGAGFVALGLPV
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHCCEE
YLWIRRDGAASTTANDPG
EEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]