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The map label for this gene is pgm [H]

Identifier: 87199672

GI number: 87199672

Start: 1731193

End: 1732821

Strand: Reverse

Name: pgm [H]

Synonym: Saro_1655

Alternate gene names: 87199672

Gene position: 1732821-1731193 (Counterclockwise)

Preceding gene: 87199673

Following gene: 87199671

Centisome position: 48.65

GC content: 63.97

Gene sequence:

>1629_bases
ATGACTCGTACCGTTCCGTCGACGCCCTGTTCCGGCCAGAAGCCGGGCACGTCCGGCCTGCGCAAGAAAGTGAAGGTCTT
CCAACAGCCGAACTACGCGGAAAACTTCATCCAGTCGGTATTCGACGTGGTCGAGCGCGCGCCTGGCAGCGCGCTGGTCG
TTGGCGGCGACGGCCGCTACCACAACCGCACCGTCATCCAGCAGGCCATCCGCATCGCCGCCGCCAACGGCTATGGCAAG
GTTCTGGTCGGTCGGGGCGGCATCCTTTCCACCCCCGCCGCATCCAACGTCATCCGCAAGTACGGCGCTTCTGGCGGCCT
GATCCTGTCGGCCAGCCACAACCCCGGCGGTCCGGACGAGGATTTCGGCATCAAGTACAACATTGCCAACGGCGGCCCTG
CTCCCGAGGCTGTAACCGAGGCGATCTATGCCCGCACCCAGACAATCGACCGCTGGCTGACCGTCGACGCGCCGGACGTC
GACCTCGACAGGCTCGGCTCAACCCAGGTCGAAGCGATGACAGTGGACGTCATAGACTCCGTTTCCGATTACGCCGAACT
CATGGAATCCCTTTTCGATTTCAATGCAATACGCGCCAATGTTGAGGGCGGGTTCACCATGGCCTTCGACGCGATGAGCG
CGGTCACCGGTCCCTACGCCATCGAGATCCTCGAAAACCGCCTCGGCTTTCCCAAGGGCACGGTGCGCAACGGCATTCCG
CTCGAGGACTTTGGGGGTCATCACCCCGATCCCAACATGGTCCACGCCCACGAGCTGTTCGATACGATGTTCGGCCCGGA
CGCTCCGGATTTCGGCGCCGCCTCCGATGGCGACGGCGATCGCAACCTGATCGTCGGCCGGCACCGCTTCGTCACCCCGT
CCGACAGCCTGGCCATGCTCGCCGCCAATGCGCACCTCGCACCGGGCTATGCCGGCGGTCTCAACGGCATTGCCCGCTCG
ATGCCGACAAGCGCTGCGGCTGATCGTGTGGCGGAGGCACTGGGCCTGCCCTGCTTCGAGACGCCAACCGGCTGGAAATT
CTTCGGAAACCTTCTCGATGCCGGCATGGCCACGATCTGCGGCGAGGAAAGCGCGGGCACCGGAAGCGACCATGTACGCG
AAAAGGACGGCCTCTGGGCGGTGCTGCTATGGCTCAACATCCTCGCGGTTCGCAGGATCGGCGTCGATCAGCTCGCACGG
GAGCATTGGGCGCGGTTCGGCCGCAACTACTACGCCCGCCACGACTACGAGGCGCTGCCGACCGACAGGGCCGATGCACT
CATGGCAGAACTCAACCAATCGCTCTCAAGTCTTTCAGGCAAGCCATTCGGAAATTTGACTATTTCGACAGCCGACAACT
TCTCCTATCTCGACCCGGTCGATGGATCGACCAGCAGCAATCAGGGTGTCCGCATCCTGTTCGAAGGTGGCTCGCGCGTG
GTCTTCCGTCTTTCCGGCACCGGCACCGAAGGCGCCACCCTGCGCGTCTATCTCGAACGCTACGAACCGGTGGGCGGCGA
TCTCGACCGTGAAACGCCTGAAATGCTTGCCGATCTCATCCGGGCGGCAGACGCCATCGCCGGCATCGCGCGTCACACCG
GACGCACCGCGCCCGACGTGGTGACGTGA

Upstream 100 bases:

>100_bases
GGCGCGCGATGCAGCGAGCCGGCATGAAGACCGACTTTTCGTGGAGCCGCTCGGGCAAGGCCTATGCGGACCTCTACGCC
GCCCTCATCGCGGAGGACCA

Downstream 100 bases:

>100_bases
CGCCGGGCGTCTTTCTGGCGGACGGCGCCACCCGCTTCTCCGTCCGCTCCCCTCGCGCCGAGGCACTGACGCTCTGCCTG
TTCGAGGACGAAGCCGAGCA

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 542; Mature: 541

Protein sequence:

>542_residues
MTRTVPSTPCSGQKPGTSGLRKKVKVFQQPNYAENFIQSVFDVVERAPGSALVVGGDGRYHNRTVIQQAIRIAAANGYGK
VLVGRGGILSTPAASNVIRKYGASGGLILSASHNPGGPDEDFGIKYNIANGGPAPEAVTEAIYARTQTIDRWLTVDAPDV
DLDRLGSTQVEAMTVDVIDSVSDYAELMESLFDFNAIRANVEGGFTMAFDAMSAVTGPYAIEILENRLGFPKGTVRNGIP
LEDFGGHHPDPNMVHAHELFDTMFGPDAPDFGAASDGDGDRNLIVGRHRFVTPSDSLAMLAANAHLAPGYAGGLNGIARS
MPTSAAADRVAEALGLPCFETPTGWKFFGNLLDAGMATICGEESAGTGSDHVREKDGLWAVLLWLNILAVRRIGVDQLAR
EHWARFGRNYYARHDYEALPTDRADALMAELNQSLSSLSGKPFGNLTISTADNFSYLDPVDGSTSSNQGVRILFEGGSRV
VFRLSGTGTEGATLRVYLERYEPVGGDLDRETPEMLADLIRAADAIAGIARHTGRTAPDVVT

Sequences:

>Translated_542_residues
MTRTVPSTPCSGQKPGTSGLRKKVKVFQQPNYAENFIQSVFDVVERAPGSALVVGGDGRYHNRTVIQQAIRIAAANGYGK
VLVGRGGILSTPAASNVIRKYGASGGLILSASHNPGGPDEDFGIKYNIANGGPAPEAVTEAIYARTQTIDRWLTVDAPDV
DLDRLGSTQVEAMTVDVIDSVSDYAELMESLFDFNAIRANVEGGFTMAFDAMSAVTGPYAIEILENRLGFPKGTVRNGIP
LEDFGGHHPDPNMVHAHELFDTMFGPDAPDFGAASDGDGDRNLIVGRHRFVTPSDSLAMLAANAHLAPGYAGGLNGIARS
MPTSAAADRVAEALGLPCFETPTGWKFFGNLLDAGMATICGEESAGTGSDHVREKDGLWAVLLWLNILAVRRIGVDQLAR
EHWARFGRNYYARHDYEALPTDRADALMAELNQSLSSLSGKPFGNLTISTADNFSYLDPVDGSTSSNQGVRILFEGGSRV
VFRLSGTGTEGATLRVYLERYEPVGGDLDRETPEMLADLIRAADAIAGIARHTGRTAPDVVT
>Mature_541_residues
TRTVPSTPCSGQKPGTSGLRKKVKVFQQPNYAENFIQSVFDVVERAPGSALVVGGDGRYHNRTVIQQAIRIAAANGYGKV
LVGRGGILSTPAASNVIRKYGASGGLILSASHNPGGPDEDFGIKYNIANGGPAPEAVTEAIYARTQTIDRWLTVDAPDVD
LDRLGSTQVEAMTVDVIDSVSDYAELMESLFDFNAIRANVEGGFTMAFDAMSAVTGPYAIEILENRLGFPKGTVRNGIPL
EDFGGHHPDPNMVHAHELFDTMFGPDAPDFGAASDGDGDRNLIVGRHRFVTPSDSLAMLAANAHLAPGYAGGLNGIARSM
PTSAAADRVAEALGLPCFETPTGWKFFGNLLDAGMATICGEESAGTGSDHVREKDGLWAVLLWLNILAVRRIGVDQLARE
HWARFGRNYYARHDYEALPTDRADALMAELNQSLSSLSGKPFGNLTISTADNFSYLDPVDGSTSSNQGVRILFEGGSRVV
FRLSGTGTEGATLRVYLERYEPVGGDLDRETPEMLADLIRAADAIAGIARHTGRTAPDVVT

Specific function: This enzyme participates in both the breakdown and synthesis of glucose. Required for the synthesis of capsular polysaccharide and normal lipopolysaccharide [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=558, Percent_Identity=51.7921146953405, Blast_Score=566, Evalue=1e-161,
Organism=Homo sapiens, GI290463102, Length=559, Percent_Identity=51.1627906976744, Blast_Score=563, Evalue=1e-160,
Organism=Homo sapiens, GI133922562, Length=560, Percent_Identity=46.0714285714286, Blast_Score=494, Evalue=1e-140,
Organism=Homo sapiens, GI290463104, Length=366, Percent_Identity=50.5464480874317, Blast_Score=371, Evalue=1e-103,
Organism=Homo sapiens, GI239741729, Length=173, Percent_Identity=41.6184971098266, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI239743670, Length=132, Percent_Identity=45.4545454545455, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1786904, Length=498, Percent_Identity=27.1084337349398, Blast_Score=93, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17535441, Length=561, Percent_Identity=47.9500891265597, Blast_Score=506, Evalue=1e-143,
Organism=Saccharomyces cerevisiae, GI6323752, Length=566, Percent_Identity=43.9929328621908, Blast_Score=472, Evalue=1e-134,
Organism=Saccharomyces cerevisiae, GI6322722, Length=528, Percent_Identity=45.0757575757576, Blast_Score=456, Evalue=1e-129,
Organism=Drosophila melanogaster, GI17864244, Length=556, Percent_Identity=48.5611510791367, Blast_Score=525, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 57807; Mature: 57676

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTVPSTPCSGQKPGTSGLRKKVKVFQQPNYAENFIQSVFDVVERAPGSALVVGGDGRY
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCC
HNRTVIQQAIRIAAANGYGKVLVGRGGILSTPAASNVIRKYGASGGLILSASHNPGGPDE
CHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCC
DFGIKYNIANGGPAPEAVTEAIYARTQTIDRWLTVDAPDVDLDRLGSTQVEAMTVDVIDS
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCHHHCCCCCCCEEEHHHHHH
VSDYAELMESLFDFNAIRANVEGGFTMAFDAMSAVTGPYAIEILENRLGFPKGTVRNGIP
HHHHHHHHHHHHHHHHHEEECCCCEEEHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCC
LEDFGGHHPDPNMVHAHELFDTMFGPDAPDFGAASDGDGDRNLIVGRHRFVTPSDSLAML
CHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCEEECCCCCEEEE
AANAHLAPGYAGGLNGIARSMPTSAAADRVAEALGLPCFETPTGWKFFGNLLDAGMATIC
EECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHC
GEESAGTGSDHVREKDGLWAVLLWLNILAVRRIGVDQLAREHWARFGRNYYARHDYEALP
CCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCC
TDRADALMAELNQSLSSLSGKPFGNLTISTADNFSYLDPVDGSTSSNQGVRILFEGGSRV
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCEE
VFRLSGTGTEGATLRVYLERYEPVGGDLDRETPEMLADLIRAADAIAGIARHTGRTAPDV
EEEEECCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VT
CC
>Mature Secondary Structure 
TRTVPSTPCSGQKPGTSGLRKKVKVFQQPNYAENFIQSVFDVVERAPGSALVVGGDGRY
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCC
HNRTVIQQAIRIAAANGYGKVLVGRGGILSTPAASNVIRKYGASGGLILSASHNPGGPDE
CHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCC
DFGIKYNIANGGPAPEAVTEAIYARTQTIDRWLTVDAPDVDLDRLGSTQVEAMTVDVIDS
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCHHHCCCCCCCEEEHHHHHH
VSDYAELMESLFDFNAIRANVEGGFTMAFDAMSAVTGPYAIEILENRLGFPKGTVRNGIP
HHHHHHHHHHHHHHHHHEEECCCCEEEHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCC
LEDFGGHHPDPNMVHAHELFDTMFGPDAPDFGAASDGDGDRNLIVGRHRFVTPSDSLAML
CHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCEEECCCCCEEEE
AANAHLAPGYAGGLNGIARSMPTSAAADRVAEALGLPCFETPTGWKFFGNLLDAGMATIC
EECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHC
GEESAGTGSDHVREKDGLWAVLLWLNILAVRRIGVDQLAREHWARFGRNYYARHDYEALP
CCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCC
TDRADALMAELNQSLSSLSGKPFGNLTISTADNFSYLDPVDGSTSSNQGVRILFEGGSRV
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCEE
VFRLSGTGTEGATLRVYLERYEPVGGDLDRETPEMLADLIRAADAIAGIARHTGRTAPDV
EEEEECCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VT
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959036; 2307661 [H]