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The map label for this gene is pksS [H]

Identifier: 87199665

GI number: 87199665

Start: 1723704

End: 1724894

Strand: Reverse

Name: pksS [H]

Synonym: Saro_1648

Alternate gene names: 87199665

Gene position: 1724894-1723704 (Counterclockwise)

Preceding gene: 87199671

Following gene: 87199664

Centisome position: 48.43

GC content: 64.32

Gene sequence:

>1191_bases
ATGGCTACCGTGATCGAGCGGCCGCAATTCCGCTTCGACCCATATTCCCCGGCAATCGACGCCGACCCGTTCCCCGCCTA
CAAGGTGCTGCGCGACGAATACCCCTGCTTCTGGTCCGAGGAGGCCGGAAAGTGGGTGCTCTCGCGCTATGACGACGTGC
TTGCAGCGCTGCAGGACTGGCGGACCTATTCTTCCGCCAAGGGCAACCTCGTGGACGAGTTTCCCGGTCGCGCCGGCTCG
ACGCTGGGATCGAGTGATCCGCCGCGCCATGACCGCCTGCGCGCCCTCATCCAGTCGGCCGTGACCAAGCGTGCGCTTGA
ACACATTATCGCACCAGCCCGGGCATCGGCCCAGGCGCATCTGGCCGCGCTGGCGGACAAGCCGGTGTTCGACCTGGTGG
GCGACTACACGTCGAAGCTGACGGTCGACCTCCTCTTCTACCTTTTCGCCCTGCCGGACGAAGGCGCGCAGCAGGTGCGC
GAGAACGCGGTGCTGATGGTCCAGACCGATCCGGTCACGCGCCAGAAGAGCCCCGAACATCTCGCGGCGTTCCATTGGAT
GGCGGACTACGCCGAAAAGCTGGTCGCCTCGCGCAAGGCGAACCCCGGCGACGACCTCCTGTCCAGCTTCATCACCGCCG
AGATCGACGGGGAGAAGTTGCTCGACAAGGAAGTCCAGCTTACCGTCACCACGCTGATCATGGCGGGCATCGAAAGCCTT
TCGGGCTTCATGGCAATGTTCGGCCTGAACCTTGCCGACTATCCCGAAGCGCGCAGCGCGCTGGTTGCCGACCCTTCGCT
GATCCCCGATGCGATCGAGGAATCGTTGCGGTTCAACACTTCCGCCCAGCGATTCAAACGGACGTTGACGCGGGACGTGG
AGCTTCACGGACAGGTGATGAAGGCTGGCGACGCGGTGATCCTCGCCTATGGATCAGCCAATCGCGACGAGCGGATGTTC
GAGAATCCGGACGTCTACGACATCACCCGCAAGCCGCGGCGCCACCTCGGCTTCGGCGGCGGTGTCCACGCCTGCCTTGG
CTCGATGATCGGGCGCCTGGCGACGCAGATCGCCTACGAGGAACTCCTGAAGGCGGTGCCCGATTTCCGGCGTGCCGACG
CCCCGCTCGACTGGGTGCCTTCATCCAACTTCCGCAGTCCGAAGTCGCTCATGCTCGAAAAGAAGGCCTGA

Upstream 100 bases:

>100_bases
ACCGATTGCATGAAAAGTACAAGGAATTGCGGCGAACCTGCGTCGCCTTCCTCACCGTGCAGAGGCAGGATGCCGGGCAC
TTGAGAGAGGACACAGGCTC

Downstream 100 bases:

>100_bases
GTTTCCGCGCGGCGGCTCGACAGGCGGCGGGTCATGCACGACTCGTCGCAAGGATGGGCCGCCGCACTTGAAGGTGTGAC
GTGCAGCATACAAATTCGGG

Product: cytochrome P450

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MATVIERPQFRFDPYSPAIDADPFPAYKVLRDEYPCFWSEEAGKWVLSRYDDVLAALQDWRTYSSAKGNLVDEFPGRAGS
TLGSSDPPRHDRLRALIQSAVTKRALEHIIAPARASAQAHLAALADKPVFDLVGDYTSKLTVDLLFYLFALPDEGAQQVR
ENAVLMVQTDPVTRQKSPEHLAAFHWMADYAEKLVASRKANPGDDLLSSFITAEIDGEKLLDKEVQLTVTTLIMAGIESL
SGFMAMFGLNLADYPEARSALVADPSLIPDAIEESLRFNTSAQRFKRTLTRDVELHGQVMKAGDAVILAYGSANRDERMF
ENPDVYDITRKPRRHLGFGGGVHACLGSMIGRLATQIAYEELLKAVPDFRRADAPLDWVPSSNFRSPKSLMLEKKA

Sequences:

>Translated_396_residues
MATVIERPQFRFDPYSPAIDADPFPAYKVLRDEYPCFWSEEAGKWVLSRYDDVLAALQDWRTYSSAKGNLVDEFPGRAGS
TLGSSDPPRHDRLRALIQSAVTKRALEHIIAPARASAQAHLAALADKPVFDLVGDYTSKLTVDLLFYLFALPDEGAQQVR
ENAVLMVQTDPVTRQKSPEHLAAFHWMADYAEKLVASRKANPGDDLLSSFITAEIDGEKLLDKEVQLTVTTLIMAGIESL
SGFMAMFGLNLADYPEARSALVADPSLIPDAIEESLRFNTSAQRFKRTLTRDVELHGQVMKAGDAVILAYGSANRDERMF
ENPDVYDITRKPRRHLGFGGGVHACLGSMIGRLATQIAYEELLKAVPDFRRADAPLDWVPSSNFRSPKSLMLEKKA
>Mature_395_residues
ATVIERPQFRFDPYSPAIDADPFPAYKVLRDEYPCFWSEEAGKWVLSRYDDVLAALQDWRTYSSAKGNLVDEFPGRAGST
LGSSDPPRHDRLRALIQSAVTKRALEHIIAPARASAQAHLAALADKPVFDLVGDYTSKLTVDLLFYLFALPDEGAQQVRE
NAVLMVQTDPVTRQKSPEHLAAFHWMADYAEKLVASRKANPGDDLLSSFITAEIDGEKLLDKEVQLTVTTLIMAGIESLS
GFMAMFGLNLADYPEARSALVADPSLIPDAIEESLRFNTSAQRFKRTLTRDVELHGQVMKAGDAVILAYGSANRDERMFE
NPDVYDITRKPRRHLGFGGGVHACLGSMIGRLATQIAYEELLKAVPDFRRADAPLDWVPSSNFRSPKSLMLEKKA

Specific function: Involved in the metabolism of the antibiotic polyketide bacillaene which is involved in secondary metabolism. The substrate is dihydrobacillaene [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 43979; Mature: 43848

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVIERPQFRFDPYSPAIDADPFPAYKVLRDEYPCFWSEEAGKWVLSRYDDVLAALQDW
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RTYSSAKGNLVDEFPGRAGSTLGSSDPPRHDRLRALIQSAVTKRALEHIIAPARASAQAH
HHHHCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LAALADKPVFDLVGDYTSKLTVDLLFYLFALPDEGAQQVRENAVLMVQTDPVTRQKSPEH
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCCCCCCHHH
LAAFHWMADYAEKLVASRKANPGDDLLSSFITAEIDGEKLLDKEVQLTVTTLIMAGIESL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
SGFMAMFGLNLADYPEARSALVADPSLIPDAIEESLRFNTSAQRFKRTLTRDVELHGQVM
HHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
KAGDAVILAYGSANRDERMFENPDVYDITRKPRRHLGFGGGVHACLGSMIGRLATQIAYE
HCCCEEEEEECCCCCCCHHCCCCCEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ELLKAVPDFRRADAPLDWVPSSNFRSPKSLMLEKKA
HHHHHCCCHHHCCCCCCCCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure 
ATVIERPQFRFDPYSPAIDADPFPAYKVLRDEYPCFWSEEAGKWVLSRYDDVLAALQDW
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RTYSSAKGNLVDEFPGRAGSTLGSSDPPRHDRLRALIQSAVTKRALEHIIAPARASAQAH
HHHHCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LAALADKPVFDLVGDYTSKLTVDLLFYLFALPDEGAQQVRENAVLMVQTDPVTRQKSPEH
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEECCCCCCCCCHHH
LAAFHWMADYAEKLVASRKANPGDDLLSSFITAEIDGEKLLDKEVQLTVTTLIMAGIESL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
SGFMAMFGLNLADYPEARSALVADPSLIPDAIEESLRFNTSAQRFKRTLTRDVELHGQVM
HHHHHHHCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
KAGDAVILAYGSANRDERMFENPDVYDITRKPRRHLGFGGGVHACLGSMIGRLATQIAYE
HCCCEEEEEECCCCCCCHHCCCCCEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ELLKAVPDFRRADAPLDWVPSSNFRSPKSLMLEKKA
HHHHHCCCHHHCCCCCCCCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]