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The map label for this gene is vllY [H]

Identifier: 87199603

GI number: 87199603

Start: 1643707

End: 1645572

Strand: Reverse

Name: vllY [H]

Synonym: Saro_1586

Alternate gene names: 87199603

Gene position: 1645572-1643707 (Counterclockwise)

Preceding gene: 87199608

Following gene: 87199602

Centisome position: 46.2

GC content: 65.92

Gene sequence:

>1866_bases
ATGAAGACCTCGATCGCCACCGTCTCGATCAGCGGCACGCTCGATGCCAAGCTGCAAGCCATTGCCGACGCTGGCTATGA
TGGCGCGGAAATCTTCGAGAACGACCTGCTCTCCACCCATCTCTCCGCACGCGAGATCGGCGCAATGATGCGCGACCTCG
GCCTCGCCTGCACGATGTTCCAACCCTTCCGCGACCTGGAAGGGCTTCCCGCCGAACAACGCGCCCGCGCCTTCGACCGG
CTCGAACGCAAGTTCGACGTGATGGAGGAACTCGGCACCGACCTGCTCCTCGCTTGCTCGTCATGCTCGCCCATTGCGGA
GGGGAACCGTGAACGCATCGTTGCCGACCTTGCCGACGCGGGAGAACGCGCCGCGCGGCGTGGGCTTCGCATCGGCTATG
AAGCGCTGGCCTGGGGTCGACACATCAATGACCACCGCGATGCGTGGAGCATCGTGCGCGACGTGGATCATCCGGCCATC
GGGTTGGTCCTCGACAGCTTCCACTCGCTTTCGCGCCGCATCCCGTCGAGCAGCATCGGCGATATCCGCCCCGAAAAGCT
TTTCATCGTCCAGGTGGCCGATGCTCCGGTCCTCAACATGGACCTCCTGCAATGGAGCCGCCATTTCCGCTCCATGCCCG
GCCAGGGCGATTTCCCGCTGGACGACTGGGCTGAAGCGATCCGCCGCATCGGCTATGATGGCTACTGGAGCCTCGAGATA
TTCAACGACCGGTTCCGCGCCGGTTCGGCGCACGGCGTTGCGCTCGACGGATATCGCTCGCTCCGCCTGATGCAGGGCGG
TATCGCCCGGGCCGCCAGCGGTGCCTCGGCGCTGCCCGCGAAGGCAAGGCCGCTCGGCGTCGAGTTCATCGAGTTTGCCG
CCAGCCACGAAGAGGCCGAGGCCCTTGGCGGCATGCTGCGCCCGCTAGGCTTCCGTCCCACCGCGCGGCACCGCACCAAG
GATGTCACTCGCTGGCAGCAAGGCGGAATCAACATCGTCGTCAACTGTGAACCGGAAGGCCTCGCCCACAGCTTCGACGT
CGTTCACGGCGCGTCGGTCTGCGCGATCGGCCTGGCCGTCGAGGACGTGCCCGCCGCACTGGCCCGCGCCGAATTCCTGC
GCGTTCCCCGCTTCGAACAGGCCGTCGCCCCCGGCGAGTGGCCAATTCCGAGCGTTCGCGGGGTGGGCGGAAGCCTGCTC
TACTTCGTCGATGCCGCGACCCGCGAAGCGATGTGGGCGCATGAATTCCCCCACGCGCTCGAACCCTTGCCCGAAGCCCC
CCTACTCACTTCGATCGACCACATCGCACAGACGATGCAGTACGAGGAGTTCCTGAGCTGGCTTCTGTTCTACGTCGCGC
TGTTCGACCTGGAAAAGACTCCGCAACTCGAGATCGCCGATCCCATGGGCCTCGTGCAGAGCCAGGCGGTGGAGAGCGCC
GACCGTTCGGTGCGCTTCACCCTCAACGGGTCGCTCGCGGCGCAGTCGCTCACTTCGCGGTTCGTGCAGAACTATTTCGG
CGCGGGCGTGCAGCATGTCGCCTTTGCCACCGGCGACGCCTTTGCAGCTTCGGAAAGCGCGGCATCCAAAGGACTTGAGC
GGCTCGCGATCCCCCGCAACTACCACGACGATCTCGAGGCGCGGTGGGGGCTGGAAGGCAACCTGGCCGACCGGATGGCC
GCCGACGATCTGCTATACGACCGCGACGGCGAGGCCGAGTACTTCCAGTTCTACAGCCGCGCCTTTGCGCGGCGCGTGTT
CTTCGAGGTGGTCGAACGGCGCGGATACGAGGGTTACGGCGCGGCGAACGCCCCGATCCGTCTCGCTGCGCAGGCTCGGC
ACAAGCCTGACCTGAACGGCCTCTAA

Upstream 100 bases:

>100_bases
CTTGCGTCACGCCGCCATTTATGTAACGAACTAGTCCCTAACATTTTGTGTTGTCAACACCGACCCGAGAGTCGGGGTGA
CGGAGAGCCCGGACCCGCGC

Downstream 100 bases:

>100_bases
CCATACACGAGACGCAAAAAAGCATACCCGAAGGGAGAGAAGAATGACCGGAAAGTTCCTCAGTGCGGCCCTGCTCGCGG
TCCTTGCCGCGCAGCCTGCG

Product: 4-hydroxyphenylpyruvate dioxygenase

Products: homogentisate; CO2

Alternate protein names: NA

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MKTSIATVSISGTLDAKLQAIADAGYDGAEIFENDLLSTHLSAREIGAMMRDLGLACTMFQPFRDLEGLPAEQRARAFDR
LERKFDVMEELGTDLLLACSSCSPIAEGNRERIVADLADAGERAARRGLRIGYEALAWGRHINDHRDAWSIVRDVDHPAI
GLVLDSFHSLSRRIPSSSIGDIRPEKLFIVQVADAPVLNMDLLQWSRHFRSMPGQGDFPLDDWAEAIRRIGYDGYWSLEI
FNDRFRAGSAHGVALDGYRSLRLMQGGIARAASGASALPAKARPLGVEFIEFAASHEEAEALGGMLRPLGFRPTARHRTK
DVTRWQQGGINIVVNCEPEGLAHSFDVVHGASVCAIGLAVEDVPAALARAEFLRVPRFEQAVAPGEWPIPSVRGVGGSLL
YFVDAATREAMWAHEFPHALEPLPEAPLLTSIDHIAQTMQYEEFLSWLLFYVALFDLEKTPQLEIADPMGLVQSQAVESA
DRSVRFTLNGSLAAQSLTSRFVQNYFGAGVQHVAFATGDAFAASESAASKGLERLAIPRNYHDDLEARWGLEGNLADRMA
ADDLLYDRDGEAEYFQFYSRAFARRVFFEVVERRGYEGYGAANAPIRLAAQARHKPDLNGL

Sequences:

>Translated_621_residues
MKTSIATVSISGTLDAKLQAIADAGYDGAEIFENDLLSTHLSAREIGAMMRDLGLACTMFQPFRDLEGLPAEQRARAFDR
LERKFDVMEELGTDLLLACSSCSPIAEGNRERIVADLADAGERAARRGLRIGYEALAWGRHINDHRDAWSIVRDVDHPAI
GLVLDSFHSLSRRIPSSSIGDIRPEKLFIVQVADAPVLNMDLLQWSRHFRSMPGQGDFPLDDWAEAIRRIGYDGYWSLEI
FNDRFRAGSAHGVALDGYRSLRLMQGGIARAASGASALPAKARPLGVEFIEFAASHEEAEALGGMLRPLGFRPTARHRTK
DVTRWQQGGINIVVNCEPEGLAHSFDVVHGASVCAIGLAVEDVPAALARAEFLRVPRFEQAVAPGEWPIPSVRGVGGSLL
YFVDAATREAMWAHEFPHALEPLPEAPLLTSIDHIAQTMQYEEFLSWLLFYVALFDLEKTPQLEIADPMGLVQSQAVESA
DRSVRFTLNGSLAAQSLTSRFVQNYFGAGVQHVAFATGDAFAASESAASKGLERLAIPRNYHDDLEARWGLEGNLADRMA
ADDLLYDRDGEAEYFQFYSRAFARRVFFEVVERRGYEGYGAANAPIRLAAQARHKPDLNGL
>Mature_621_residues
MKTSIATVSISGTLDAKLQAIADAGYDGAEIFENDLLSTHLSAREIGAMMRDLGLACTMFQPFRDLEGLPAEQRARAFDR
LERKFDVMEELGTDLLLACSSCSPIAEGNRERIVADLADAGERAARRGLRIGYEALAWGRHINDHRDAWSIVRDVDHPAI
GLVLDSFHSLSRRIPSSSIGDIRPEKLFIVQVADAPVLNMDLLQWSRHFRSMPGQGDFPLDDWAEAIRRIGYDGYWSLEI
FNDRFRAGSAHGVALDGYRSLRLMQGGIARAASGASALPAKARPLGVEFIEFAASHEEAEALGGMLRPLGFRPTARHRTK
DVTRWQQGGINIVVNCEPEGLAHSFDVVHGASVCAIGLAVEDVPAALARAEFLRVPRFEQAVAPGEWPIPSVRGVGGSLL
YFVDAATREAMWAHEFPHALEPLPEAPLLTSIDHIAQTMQYEEFLSWLLFYVALFDLEKTPQLEIADPMGLVQSQAVESA
DRSVRFTLNGSLAAQSLTSRFVQNYFGAGVQHVAFATGDAFAASESAASKGLERLAIPRNYHDDLEARWGLEGNLADRMA
ADDLLYDRDGEAEYFQFYSRAFARRVFFEVVERRGYEGYGAANAPIRLAAQARHKPDLNGL

Specific function: Unknown

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 4HPPD family [H]

Homologues:

Organism=Homo sapiens, GI285002264, Length=279, Percent_Identity=25.089605734767, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4504477, Length=279, Percent_Identity=25.089605734767, Blast_Score=74, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17555220, Length=280, Percent_Identity=23.9285714285714, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005956
- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 1.13.11.27

Molecular weight: Translated: 68403; Mature: 68403

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSIATVSISGTLDAKLQAIADAGYDGAEIFENDLLSTHLSAREIGAMMRDLGLACTMF
CCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QPFRDLEGLPAEQRARAFDRLERKFDVMEELGTDLLLACSSCSPIAEGNRERIVADLADA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEHCCCCCCCCCCCHHHHHHHHHHH
GERAARRGLRIGYEALAWGRHINDHRDAWSIVRDVDHPAIGLVLDSFHSLSRRIPSSSIG
HHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCC
DIRPEKLFIVQVADAPVLNMDLLQWSRHFRSMPGQGDFPLDDWAEAIRRIGYDGYWSLEI
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEE
FNDRFRAGSAHGVALDGYRSLRLMQGGIARAASGASALPAKARPLGVEFIEFAASHEEAE
ECCHHCCCCCCCEEECCHHHHHHHHCCHHHHCCCCCCCCCCCCCCCHHHHHHHHCHHHHH
ALGGMLRPLGFRPTARHRTKDVTRWQQGGINIVVNCEPEGLAHSFDVVHGASVCAIGLAV
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCHHHHHHHHH
EDVPAALARAEFLRVPRFEQAVAPGEWPIPSVRGVGGSLLYFVDAATREAMWAHEFPHAL
HHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCHHH
EPLPEAPLLTSIDHIAQTMQYEEFLSWLLFYVALFDLEKTPQLEIADPMGLVQSQAVESA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHC
DRSVRFTLNGSLAAQSLTSRFVQNYFGAGVQHVAFATGDAFAASESAASKGLERLAIPRN
CCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHEEECCCCHHHCHHHHHHCHHHHCCCCC
YHDDLEARWGLEGNLADRMAADDLLYDRDGEAEYFQFYSRAFARRVFFEVVERRGYEGYG
CCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AANAPIRLAAQARHKPDLNGL
CCCCCEEEEEHHCCCCCCCCC
>Mature Secondary Structure
MKTSIATVSISGTLDAKLQAIADAGYDGAEIFENDLLSTHLSAREIGAMMRDLGLACTMF
CCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QPFRDLEGLPAEQRARAFDRLERKFDVMEELGTDLLLACSSCSPIAEGNRERIVADLADA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEHCCCCCCCCCCCHHHHHHHHHHH
GERAARRGLRIGYEALAWGRHINDHRDAWSIVRDVDHPAIGLVLDSFHSLSRRIPSSSIG
HHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCC
DIRPEKLFIVQVADAPVLNMDLLQWSRHFRSMPGQGDFPLDDWAEAIRRIGYDGYWSLEI
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEE
FNDRFRAGSAHGVALDGYRSLRLMQGGIARAASGASALPAKARPLGVEFIEFAASHEEAE
ECCHHCCCCCCCEEECCHHHHHHHHCCHHHHCCCCCCCCCCCCCCCHHHHHHHHCHHHHH
ALGGMLRPLGFRPTARHRTKDVTRWQQGGINIVVNCEPEGLAHSFDVVHGASVCAIGLAV
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCHHHHHHHHH
EDVPAALARAEFLRVPRFEQAVAPGEWPIPSVRGVGGSLLYFVDAATREAMWAHEFPHAL
HHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCHHH
EPLPEAPLLTSIDHIAQTMQYEEFLSWLLFYVALFDLEKTPQLEIADPMGLVQSQAVESA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHC
DRSVRFTLNGSLAAQSLTSRFVQNYFGAGVQHVAFATGDAFAASESAASKGLERLAIPRN
CCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHEEECCCCHHHCHHHHHHCHHHHCCCCC
YHDDLEARWGLEGNLADRMAADDLLYDRDGEAEYFQFYSRAFARRVFFEVVERRGYEGYG
CCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AANAPIRLAAQARHKPDLNGL
CCCCCEEEEEHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-hydroxyphenylpyruvate; O2

Specific reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA