| Definition | Novosphingobium aromaticivorans DSM 12444 chromosome, complete genome. |
|---|---|
| Accession | NC_007794 |
| Length | 3,561,584 |
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The map label for this gene is ppi [H]
Identifier: 87198988
GI number: 87198988
Start: 1012810
End: 1013265
Strand: Direct
Name: ppi [H]
Synonym: Saro_0966
Alternate gene names: 87198988
Gene position: 1012810-1013265 (Clockwise)
Preceding gene: 87198985
Following gene: 87198993
Centisome position: 28.44
GC content: 64.47
Gene sequence:
>456_bases ATGGCTGATGAAAAACTGGTCCTCTCGCTCGACTCCGGCGATGTTGTGATCAAGCTGCGCCCCGATCTGGCCCCGGGCCA TGTGGAGCGCATCAAGGAACTCGCGAACGAGGGCTTCTACGACGGCGTGAAGTTCCACCGCGTGATCCCCGGCTTCATGG CGCAGGGCGGTTGTCCGCAGGGCACCGGCATGGGCGGTTCGAGCAAGCCGGATCTCAAGGCCGAATTCAACGACGAACCG CACGTGCGCGGCGTGTGTTCGATGGCGCGCACCAGCTATCCGCACTCGGCCAACAGCCAGTTCTTCATCTGCTTCGACGA TGCGCGCTTCCTCGACAAGCAGTACACCGTCTGGGGCCAGGTCGAGAGCGGCATGGAACACATCGACGCGCTGCCCAAGG GCGAGCCGCCGGCAAACCCGGGCGTGATCCGCAAGGCGAGCGTTGTCGCCGCCTGA
Upstream 100 bases:
>100_bases TAGCCACTGGGACGCCAATTGCAACCGTCTGGCAGACCTATGCGTGACTTTCTTGTCCAACCCCTTATATCCCCCGTCAA ACAGGAAGGAATTGCGACAA
Downstream 100 bases:
>100_bases TCGGGATTACCCGTTGAAATGAAAAGGGGCGGGGCCGATGGGCCGCCGCCCCTTTTCATTTCATGCGGACAGGCGGCGTA CAGCCTCGTCCTGCGCGATC
Product: cyclophilin type peptidyl-prolyl cis-trans isomerase
Products: NA
Alternate protein names: PPIase; Rotamase [H]
Number of amino acids: Translated: 151; Mature: 150
Protein sequence:
>151_residues MADEKLVLSLDSGDVVIKLRPDLAPGHVERIKELANEGFYDGVKFHRVIPGFMAQGGCPQGTGMGGSSKPDLKAEFNDEP HVRGVCSMARTSYPHSANSQFFICFDDARFLDKQYTVWGQVESGMEHIDALPKGEPPANPGVIRKASVVAA
Sequences:
>Translated_151_residues MADEKLVLSLDSGDVVIKLRPDLAPGHVERIKELANEGFYDGVKFHRVIPGFMAQGGCPQGTGMGGSSKPDLKAEFNDEP HVRGVCSMARTSYPHSANSQFFICFDDARFLDKQYTVWGQVESGMEHIDALPKGEPPANPGVIRKASVVAA >Mature_150_residues ADEKLVLSLDSGDVVIKLRPDLAPGHVERIKELANEGFYDGVKFHRVIPGFMAQGGCPQGTGMGGSSKPDLKAEFNDEPH VRGVCSMARTSYPHSANSQFFICFDDARFLDKQYTVWGQVESGMEHIDALPKGEPPANPGVIRKASVVAA
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Periplasm (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI19557636, Length=145, Percent_Identity=40, Blast_Score=89, Evalue=2e-18, Organism=Homo sapiens, GI7706339, Length=131, Percent_Identity=35.8778625954198, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI64276486, Length=158, Percent_Identity=34.8101265822785, Blast_Score=80, Evalue=5e-16, Organism=Homo sapiens, GI24308049, Length=147, Percent_Identity=36.0544217687075, Blast_Score=79, Evalue=2e-15, Organism=Homo sapiens, GI22547215, Length=141, Percent_Identity=41.8439716312057, Blast_Score=72, Evalue=1e-13, Organism=Homo sapiens, GI310127646, Length=132, Percent_Identity=36.3636363636364, Blast_Score=72, Evalue=2e-13, Organism=Homo sapiens, GI310114371, Length=132, Percent_Identity=36.3636363636364, Blast_Score=72, Evalue=2e-13, Organism=Homo sapiens, GI310119221, Length=132, Percent_Identity=36.3636363636364, Blast_Score=72, Evalue=2e-13, Organism=Homo sapiens, GI310129267, Length=128, Percent_Identity=37.5, Blast_Score=72, Evalue=2e-13, Organism=Homo sapiens, GI310120620, Length=128, Percent_Identity=37.5, Blast_Score=72, Evalue=2e-13, Organism=Homo sapiens, GI10863927, Length=130, Percent_Identity=37.6923076923077, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI22547212, Length=141, Percent_Identity=41.8439716312057, Blast_Score=70, Evalue=7e-13, Organism=Homo sapiens, GI7657473, Length=141, Percent_Identity=41.8439716312057, Blast_Score=70, Evalue=7e-13, Organism=Homo sapiens, GI256017253, Length=129, Percent_Identity=37.2093023255814, Blast_Score=70, Evalue=9e-13, Organism=Homo sapiens, GI221139811, Length=129, Percent_Identity=37.2093023255814, Blast_Score=70, Evalue=9e-13, Organism=Homo sapiens, GI256017251, Length=129, Percent_Identity=37.2093023255814, Blast_Score=70, Evalue=9e-13, Organism=Homo sapiens, GI310110104, Length=128, Percent_Identity=36.71875, Blast_Score=69, Evalue=1e-12, Organism=Homo sapiens, GI5031987, Length=128, Percent_Identity=39.0625, Blast_Score=69, Evalue=1e-12, Organism=Homo sapiens, GI178057341, Length=130, Percent_Identity=36.1538461538462, Blast_Score=68, Evalue=2e-12, Organism=Homo sapiens, GI45439316, Length=136, Percent_Identity=35.2941176470588, Blast_Score=66, Evalue=1e-11, Organism=Escherichia coli, GI1789763, Length=162, Percent_Identity=35.8024691358025, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1786736, Length=146, Percent_Identity=36.986301369863, Blast_Score=85, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17539496, Length=129, Percent_Identity=37.2093023255814, Blast_Score=82, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17532641, Length=134, Percent_Identity=35.0746268656716, Blast_Score=76, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17506311, Length=131, Percent_Identity=35.8778625954198, Blast_Score=75, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17539498, Length=143, Percent_Identity=37.0629370629371, Blast_Score=73, Evalue=5e-14, Organism=Caenorhabditis elegans, GI71980594, Length=132, Percent_Identity=36.3636363636364, Blast_Score=71, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71980590, Length=132, Percent_Identity=36.3636363636364, Blast_Score=71, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71997782, Length=128, Percent_Identity=36.71875, Blast_Score=67, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17552782, Length=151, Percent_Identity=34.4370860927152, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17565860, Length=135, Percent_Identity=34.0740740740741, Blast_Score=64, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17559074, Length=134, Percent_Identity=33.5820895522388, Blast_Score=64, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6320359, Length=148, Percent_Identity=37.8378378378378, Blast_Score=66, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6323562, Length=128, Percent_Identity=35.9375, Blast_Score=62, Evalue=3e-11, Organism=Drosophila melanogaster, GI17986117, Length=154, Percent_Identity=37.6623376623377, Blast_Score=91, Evalue=4e-19, Organism=Drosophila melanogaster, GI17647301, Length=130, Percent_Identity=37.6923076923077, Blast_Score=74, Evalue=3e-14, Organism=Drosophila melanogaster, GI19922376, Length=140, Percent_Identity=37.1428571428571, Blast_Score=74, Evalue=5e-14, Organism=Drosophila melanogaster, GI24652460, Length=145, Percent_Identity=37.2413793103448, Blast_Score=72, Evalue=1e-13, Organism=Drosophila melanogaster, GI45549139, Length=128, Percent_Identity=35.9375, Blast_Score=67, Evalue=3e-12, Organism=Drosophila melanogaster, GI24664125, Length=128, Percent_Identity=36.71875, Blast_Score=67, Evalue=4e-12, Organism=Drosophila melanogaster, GI21357783, Length=128, Percent_Identity=36.71875, Blast_Score=67, Evalue=4e-12, Organism=Drosophila melanogaster, GI19922912, Length=147, Percent_Identity=39.4557823129252, Blast_Score=65, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR020892 - InterPro: IPR002130 [H]
Pfam domain/function: PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 16360; Mature: 16229
Theoretical pI: Translated: 6.00; Mature: 6.00
Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 5.3 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 4.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MADEKLVLSLDSGDVVIKLRPDLAPGHVERIKELANEGFYDGVKFHRVIPGFMAQGGCPQ CCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCHHHHCCCCCC GTGMGGSSKPDLKAEFNDEPHVRGVCSMARTSYPHSANSQFFICFDDARFLDKQYTVWGQ CCCCCCCCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHCCCCEEECC VESGMEHIDALPKGEPPANPGVIRKASVVAA HHHHHHHHHCCCCCCCCCCCCCEECCEEECC >Mature Secondary Structure ADEKLVLSLDSGDVVIKLRPDLAPGHVERIKELANEGFYDGVKFHRVIPGFMAQGGCPQ CCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCHHHHCCCCCC GTGMGGSSKPDLKAEFNDEPHVRGVCSMARTSYPHSANSQFFICFDDARFLDKQYTVWGQ CCCCCCCCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHCCCCEEECC VESGMEHIDALPKGEPPANPGVIRKASVVAA HHHHHHHHHCCCCCCCCCCCCCEECCEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA