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The map label for this gene is ctaC [H]

Identifier: 87198935

GI number: 87198935

Start: 966385

End: 967434

Strand: Direct

Name: ctaC [H]

Synonym: Saro_0913

Alternate gene names: 87198935

Gene position: 966385-967434 (Clockwise)

Preceding gene: 87198925

Following gene: 87198936

Centisome position: 27.13

GC content: 67.52

Gene sequence:

>1050_bases
ATGAGTCTTGCCGATACCGCCCGCGCCACGGGCAAAGCCATCCGGACCCTCGGCGTTGCTGCCGCACTGGCGTTCGGGAC
CCAGGCGATCGCCGCCACCCCCGCCGCGCCGGTCGCTGCTCCGGCTGCTGCCGCCAGCGAATCGGCTGCCGCTGCTCCGG
CTGCGGCCGCTGCTGCTGCCGATACCGCCGACAAGGGTTCCTATGTTCCCATGAAGCCGACGCCCGGCAAGGGTCAGCCG
GTTGACGGGGGCTGGACCTTCCAGGACCAGTATTCGCCCATCGGCGATCAGGGCCTGTGGATGCACGACTACGTGCTGAT
GCCGGTCATCGTCGCGATCACGCTGCTGGTGCTGATCCTGCTGCTGGTGGTGATGGCGAAGTTCCGCCGCGCCGCCAACC
CGGTCGCGTCGAAGACCAGCCACAACACGCTGATCGAAGTTATCTGGACGCTGATCCCGGTGCTTATCCTGGTGGTCATC
GCGGTTCCGTCGATCCGCCTTCTGGCCCACCAGTACGAGCCGGCGCCGAAGGGCGCGCTGACCGTCAAGGTCACCGGCTA
CCAGTGGTACTGGGGTTACACCTATCCCGACAACGGCGGCTTCGAAGTCATTTCGAACATGCTGCCCGAGGAAGAAGCCC
TGAAGCGCGGCGAGCCCGGCCATCTTGCGGTCGACAACCGCATGGTCGTTCCCGCGGGCGAGCCGATCCGCATCCAGACC
ATCGGTTCGGACGTGATCCACTCGTTCGCCGTGCCTTCGCTGTGGTTCAAGCTGGACGCCGTTCCGGGCCGGATCAACGA
GAAGGTGCTCTTCATCAAGGAGCCGGGTCTCTATTACGGCCAGTGCTCCGAACTGTGCGGCGCCCGCCACGGCTACATGC
CGATCGCGGTCGAGGCCCTGCCGCGCGCCAAGTTCGAGGCATGGGTGAAGACCCAGCCCGGCGGCACCGTCGGCCCGGTT
GCCGAAGCTGCTCCCGCTGCCGTTCCTGCGGCAGCCGCAGCTCCCGCCGAAGCCCCGGCCGCCGACGCTTCCGCAGCGCC
TGCCGCCTGA

Upstream 100 bases:

>100_bases
GTATAGGCCGCTGCAATCGAGGGACTTAGAGGGGGTGCGCATGCGCCTCCTTGATGCAGCGCAAAACGCGCGCAAACAGG
GAAAAGCGGAAACTTCGACG

Downstream 100 bases:

>100_bases
CGAATTCATCGACAAGGTTTGACCGAGATGGCCACCATACCAGCTAACGAAGGCTTCGATGCGCATCACGATGCGCACGA
CCACGACCATGATCATCCGG

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSLADTARATGKAIRTLGVAAALAFGTQAIAATPAAPVAAPAAAASESAAAAPAAAAAAADTADKGSYVPMKPTPGKGQP
VDGGWTFQDQYSPIGDQGLWMHDYVLMPVIVAITLLVLILLLVVMAKFRRAANPVASKTSHNTLIEVIWTLIPVLILVVI
AVPSIRLLAHQYEPAPKGALTVKVTGYQWYWGYTYPDNGGFEVISNMLPEEEALKRGEPGHLAVDNRMVVPAGEPIRIQT
IGSDVIHSFAVPSLWFKLDAVPGRINEKVLFIKEPGLYYGQCSELCGARHGYMPIAVEALPRAKFEAWVKTQPGGTVGPV
AEAAPAAVPAAAAAPAEAPAADASAAPAA

Sequences:

>Translated_349_residues
MSLADTARATGKAIRTLGVAAALAFGTQAIAATPAAPVAAPAAAASESAAAAPAAAAAAADTADKGSYVPMKPTPGKGQP
VDGGWTFQDQYSPIGDQGLWMHDYVLMPVIVAITLLVLILLLVVMAKFRRAANPVASKTSHNTLIEVIWTLIPVLILVVI
AVPSIRLLAHQYEPAPKGALTVKVTGYQWYWGYTYPDNGGFEVISNMLPEEEALKRGEPGHLAVDNRMVVPAGEPIRIQT
IGSDVIHSFAVPSLWFKLDAVPGRINEKVLFIKEPGLYYGQCSELCGARHGYMPIAVEALPRAKFEAWVKTQPGGTVGPV
AEAAPAAVPAAAAAPAEAPAADASAAPAA
>Mature_348_residues
SLADTARATGKAIRTLGVAAALAFGTQAIAATPAAPVAAPAAAASESAAAAPAAAAAAADTADKGSYVPMKPTPGKGQPV
DGGWTFQDQYSPIGDQGLWMHDYVLMPVIVAITLLVLILLLVVMAKFRRAANPVASKTSHNTLIEVIWTLIPVLILVVIA
VPSIRLLAHQYEPAPKGALTVKVTGYQWYWGYTYPDNGGFEVISNMLPEEEALKRGEPGHLAVDNRMVVPAGEPIRIQTI
GSDVIHSFAVPSLWFKLDAVPGRINEKVLFIKEPGLYYGQCSELCGARHGYMPIAVEALPRAKFEAWVKTQPGGTVGPVA
EAAPAAVPAAAAAPAEAPAADASAAPAA

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=221, Percent_Identity=42.0814479638009, Blast_Score=170, Evalue=2e-42,
Organism=Escherichia coli, GI1786635, Length=228, Percent_Identity=27.1929824561404, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6226540, Length=232, Percent_Identity=40.948275862069, Blast_Score=167, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 36281; Mature: 36150

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLADTARATGKAIRTLGVAAALAFGTQAIAATPAAPVAAPAAAASESAAAAPAAAAAAA
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHCCCHHHCCCHHHHHHH
DTADKGSYVPMKPTPGKGQPVDGGWTFQDQYSPIGDQGLWMHDYVLMPVIVAITLLVLIL
CCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLVVMAKFRRAANPVASKTSHNTLIEVIWTLIPVLILVVIAVPSIRLLAHQYEPAPKGAL
HHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCEE
TVKVTGYQWYWGYTYPDNGGFEVISNMLPEEEALKRGEPGHLAVDNRMVVPAGEPIRIQT
EEEEEEEEEEEEEECCCCCCHHHHHHHCCCHHHHHCCCCCCEEECCEEEECCCCCEEEEE
IGSDVIHSFAVPSLWFKLDAVPGRINEKVLFIKEPGLYYGQCSELCGARHGYMPIAVEAL
CCHHHHHHHHHHHHHEEEECCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCEEEHHHH
PRAKFEAWVKTQPGGTVGPVAEAAPAAVPAAAAAPAEAPAADASAAPAA
CCHHHHHEEEECCCCCCCCHHHHCCCCCCHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLADTARATGKAIRTLGVAAALAFGTQAIAATPAAPVAAPAAAASESAAAAPAAAAAAA
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHCCCHHHCCCHHHHHHH
DTADKGSYVPMKPTPGKGQPVDGGWTFQDQYSPIGDQGLWMHDYVLMPVIVAITLLVLIL
CCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLVVMAKFRRAANPVASKTSHNTLIEVIWTLIPVLILVVIAVPSIRLLAHQYEPAPKGAL
HHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCEE
TVKVTGYQWYWGYTYPDNGGFEVISNMLPEEEALKRGEPGHLAVDNRMVVPAGEPIRIQT
EEEEEEEEEEEEEECCCCCCHHHHHHHCCCHHHHHCCCCCCEEECCEEEECCCCCEEEEE
IGSDVIHSFAVPSLWFKLDAVPGRINEKVLFIKEPGLYYGQCSELCGARHGYMPIAVEAL
CCHHHHHHHHHHHHHEEEECCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCEEEHHHH
PRAKFEAWVKTQPGGTVGPVAEAAPAAVPAAAAAPAEAPAADASAAPAA
CCHHHHHEEEECCCCCCCCHHHHCCCCCCHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA