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The map label for this gene is crt [H]

Identifier: 87198881

GI number: 87198881

Start: 909537

End: 910583

Strand: Direct

Name: crt [H]

Synonym: Saro_0859

Alternate gene names: 87198881

Gene position: 909537-910583 (Clockwise)

Preceding gene: 87198880

Following gene: 87198882

Centisome position: 25.54

GC content: 66.28

Gene sequence:

>1047_bases
GTGATCGACGAAGTACTTGCCAAACGCGAAGGCGCCGCCGGCATCCTTTCGCTCAACCGGCCCAAGGCGATCCACGCGCT
GACGCTGGACATGGTCCATGCGATGACTGCCTCGCTTCTCCAATGGCGTGGCGATGCCTCGGTTGGCGTGGTCCTGATCG
ACCATGCCGAAGGGCGTGGTTTCTGCGCGGGCGGCGACATTGCCTTCCTGCGCAATTCGGCGCTGAACGACGGGGGCACC
TCGGGTCGCAGGTTCTTCCACGACGAATACCAGCTCAACCACCTGCTGATGACCTACGGAAAGCCCGTGGTGGCCTTCAT
GGACGGCATCACCATGGGCGGCGGCGTCGGCATTTCCGGTCCGGCGACCTACCGCGTAGCCACCGAAAGCACCAAGCTCG
CCATGCCCGAAACGGGGATCGGCCTGTTTCCGGACGTCGGTGGCGGCTGGTTCCTTTCGCGGCTGAAGGGGCGGCTTGGC
CAGTACCTTGCGCTCACCGGCGCGCGGCTGGACGGCGCGGAATGCCTCTGGGCGGGCCTTGCCAGCCATTACCTGCCGGC
GGAGAATCTGGCCGAGGCCAAGGCACGCATCGCCGCCGATCCCGCCTCGATCCCCACCATTCTGCGCGAACTTTCCGCCG
TCCCGCCCGAGCCGAAGATCGCGGCCCATGCCGCCGAGATCGAGCGGCTGTTCGCTTCGGACCGCTACGAGGACATCCTT
GGCGCGCTCGATGCGGATGGTTCGGATTTTGCCGCGGCCACGCTGGCGACCCTTCGCACCAAGAGCCCGCAGACCTGCAA
GGTCGCACTGCGCCAGCTCGCCACGAGCCTGACCCTGCCCGATTTCGCCGCCAACATGGCGATGGAGTATCGGGTCGGTT
CGCGCGTGCTCGTCCTGCCCGACTTTGCCGAGGGCGTGCGCGCGGTCATCGTCGACAAGGACCACGCTCCGAAGTGGTCG
CCTGAGACGGCGGAAGGCGTTACCGACGACCTCCTCGACCAGATTTTCGCGCCGCTTCCGCCTGCGGAGGAATGGCAGCC
ACTTTAA

Upstream 100 bases:

>100_bases
ATTACCCGATCGAGCGCTTCTGGCGCGACCTTCGCGTCCACCGCATCCTCGAAGGCACGAACGAAGTCATGCGCATGATC
GTGGGAAGGGACCTCTTGAA

Downstream 100 bases:

>100_bases
GAGCAGCGTCATGCTGAACTCGTTTCAGCATCCATCGTGCCCCACGCGCGATGCTCCGAATTGAAACATGGACCCTGAAA
CAAGTTCAGGGTGACGAATT

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MIDEVLAKREGAAGILSLNRPKAIHALTLDMVHAMTASLLQWRGDASVGVVLIDHAEGRGFCAGGDIAFLRNSALNDGGT
SGRRFFHDEYQLNHLLMTYGKPVVAFMDGITMGGGVGISGPATYRVATESTKLAMPETGIGLFPDVGGGWFLSRLKGRLG
QYLALTGARLDGAECLWAGLASHYLPAENLAEAKARIAADPASIPTILRELSAVPPEPKIAAHAAEIERLFASDRYEDIL
GALDADGSDFAAATLATLRTKSPQTCKVALRQLATSLTLPDFAANMAMEYRVGSRVLVLPDFAEGVRAVIVDKDHAPKWS
PETAEGVTDDLLDQIFAPLPPAEEWQPL

Sequences:

>Translated_348_residues
MIDEVLAKREGAAGILSLNRPKAIHALTLDMVHAMTASLLQWRGDASVGVVLIDHAEGRGFCAGGDIAFLRNSALNDGGT
SGRRFFHDEYQLNHLLMTYGKPVVAFMDGITMGGGVGISGPATYRVATESTKLAMPETGIGLFPDVGGGWFLSRLKGRLG
QYLALTGARLDGAECLWAGLASHYLPAENLAEAKARIAADPASIPTILRELSAVPPEPKIAAHAAEIERLFASDRYEDIL
GALDADGSDFAAATLATLRTKSPQTCKVALRQLATSLTLPDFAANMAMEYRVGSRVLVLPDFAEGVRAVIVDKDHAPKWS
PETAEGVTDDLLDQIFAPLPPAEEWQPL
>Mature_348_residues
MIDEVLAKREGAAGILSLNRPKAIHALTLDMVHAMTASLLQWRGDASVGVVLIDHAEGRGFCAGGDIAFLRNSALNDGGT
SGRRFFHDEYQLNHLLMTYGKPVVAFMDGITMGGGVGISGPATYRVATESTKLAMPETGIGLFPDVGGGWFLSRLKGRLG
QYLALTGARLDGAECLWAGLASHYLPAENLAEAKARIAADPASIPTILRELSAVPPEPKIAAHAAEIERLFASDRYEDIL
GALDADGSDFAAATLATLRTKSPQTCKVALRQLATSLTLPDFAANMAMEYRVGSRVLVLPDFAEGVRAVIVDKDHAPKWS
PETAEGVTDDLLDQIFAPLPPAEEWQPL

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=348, Percent_Identity=41.3793103448276, Blast_Score=258, Evalue=6e-69,
Organism=Homo sapiens, GI37594469, Length=303, Percent_Identity=40.9240924092409, Blast_Score=218, Evalue=7e-57,
Organism=Homo sapiens, GI194097323, Length=208, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1787660, Length=269, Percent_Identity=29.368029739777, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787659, Length=263, Percent_Identity=26.615969581749, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25144160, Length=346, Percent_Identity=42.7745664739884, Blast_Score=278, Evalue=4e-75,
Organism=Caenorhabditis elegans, GI25144157, Length=346, Percent_Identity=42.7745664739884, Blast_Score=277, Evalue=5e-75,
Organism=Caenorhabditis elegans, GI25145438, Length=215, Percent_Identity=28.3720930232558, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17549921, Length=194, Percent_Identity=25.7731958762887, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=178, Percent_Identity=29.7752808988764, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320241, Length=378, Percent_Identity=33.8624338624339, Blast_Score=184, Evalue=3e-47,
Organism=Drosophila melanogaster, GI28571729, Length=345, Percent_Identity=40.8695652173913, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI28571730, Length=345, Percent_Identity=40.8695652173913, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI20129971, Length=178, Percent_Identity=27.5280898876405, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24653477, Length=178, Percent_Identity=27.5280898876405, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 37088; Mature: 37088

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDEVLAKREGAAGILSLNRPKAIHALTLDMVHAMTASLLQWRGDASVGVVLIDHAEGRG
CCHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
FCAGGDIAFLRNSALNDGGTSGRRFFHDEYQLNHLLMTYGKPVVAFMDGITMGGGVGISG
EECCCCHHHHHHCCCCCCCCCCCCEECHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCC
PATYRVATESTKLAMPETGIGLFPDVGGGWFLSRLKGRLGQYLALTGARLDGAECLWAGL
CCEEEEEECCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
ASHYLPAENLAEAKARIAADPASIPTILRELSAVPPEPKIAAHAAEIERLFASDRYEDIL
HHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHH
GALDADGSDFAAATLATLRTKSPQTCKVALRQLATSLTLPDFAANMAMEYRVGSRVLVLP
HHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHEEECCCEEEEEC
DFAEGVRAVIVDKDHAPKWSPETAEGVTDDLLDQIFAPLPPAEEWQPL
CHHCCCEEEEEECCCCCCCCCCHHCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIDEVLAKREGAAGILSLNRPKAIHALTLDMVHAMTASLLQWRGDASVGVVLIDHAEGRG
CCHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
FCAGGDIAFLRNSALNDGGTSGRRFFHDEYQLNHLLMTYGKPVVAFMDGITMGGGVGISG
EECCCCHHHHHHCCCCCCCCCCCCEECHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCC
PATYRVATESTKLAMPETGIGLFPDVGGGWFLSRLKGRLGQYLALTGARLDGAECLWAGL
CCEEEEEECCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
ASHYLPAENLAEAKARIAADPASIPTILRELSAVPPEPKIAAHAAEIERLFASDRYEDIL
HHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHH
GALDADGSDFAAATLATLRTKSPQTCKVALRQLATSLTLPDFAANMAMEYRVGSRVLVLP
HHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHEEECCCEEEEEC
DFAEGVRAVIVDKDHAPKWSPETAEGVTDDLLDQIFAPLPPAEEWQPL
CHHCCCEEEEEECCCCCCCCCCHHCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]