Click here to switch to the map view.

The map label for this gene is pabB [H]

Identifier: 87198470

GI number: 87198470

Start: 487393

End: 489180

Strand: Direct

Name: pabB [H]

Synonym: Saro_0445

Alternate gene names: 87198470

Gene position: 487393-489180 (Clockwise)

Preceding gene: 87198468

Following gene: 87198471

Centisome position: 13.68

GC content: 68.74

Gene sequence:

>1788_bases
ATGACCCGTGCTCCCTTCATCCTGCTCGACGACGCCCGCAGCGAGGGCGCGAGTGATGCGCGCCTCTACGAGGACGCCGT
CGAGATCGTCGTCGCGCGCCGCGCCGAGGAGGTCGAGGCCGCGCTTGAACGGATCGCGGCTGTCCCCGGCAACTGGGCAG
GCTACCTCGCCTACGAGGCGGGCCTCGCGCTCGAACCGCGTCTCTTGCCGCTGGCGGCGGTGCGAACCGGTGCTGACGGC
CCGTTGGTGTGGTTCGCGCGCTTCGACCGCGTCACCCGGATGCCGAGCGCGGAGGTCGAGCAGTGGCTGGTGCGCAATGC
GCGCGGCCCCGGGCGCCTCGGTCCGCTCGGCCCTGCGCTGTCGTCGGGCGGCTATGCCCGCGCCTTCGACCTGGTGCAGG
AGGCGATCCGCGCGGGCGACATCTACCAGGCGAACCTGACCTTCCCGCTGACCGGCACCTGGGATGGCGATCCGCTGTCG
ATCTACGGCGAAGTGCGCCGCGATGCGCGCGCGGGCTATGGCGGCGTGATATGGGACGGCGCGCATTGGCACCTCTCGTT
CTCGCCCGAACTCTTCTTCAAGCTTTCCGGCGGAGAAGCGCGGGTGCGCCCGATGAAGGGCACTGCCCCGCGCGGGGCAA
CCCCCGAAGAGGACGCGCGCTTCAAGGCCGACCTCTCCGCCAGTGTAAAAGACCGCGCCGAAAACCTGATGATCGTCGAT
CTCATGCGAAACGATCTCGCGCGCGTTTCACAGGCCGGGTCGGTCAAGGTCGAGGCGCCCTTCGCCATCGAATCCTATCC
TACCGTCCACCAGATGGTCACCACCGTGCGCGCCAGGCTTGCCCCCGGCGAGGACGTGCGCAGCCTCCTGCGCGCGATCT
TCCCCTGCGGTTCGATCACCGGAGCGCCCAAGATCCGCGCGATGGAGATCATCCATGCCGCAGAACGGGACGCGCGCGGG
CTCTATTGCGGCTCGATCGGACGGATCGACCCCACTGGCGAGGCGGCGTTCAATGTGGCAATCCGCACGCTGCGTCTTTC
GAGCGATCACGCCGGGGCCTCCGGGGGCCGCGCGGTCATGGGCGTCGGCTCTGCGGTCGTTGCCGATTCGGCCATGATCG
GCGAATGGCGGGAATGCGTGGTGAAGGGGAATTTCTTGCGTCTGTCCGCCGGCCATGCCGACCTTATCGAGACCATGGCC
TTCGATCCGGCCAAGGGTATCGAACTGCTCGAACTGCACCTCGAACGCATGAAGGCCAGTGCGCTTGCGCTAGGCTACAG
CTTCGACCGGCACGCGGTGCGCAATGCGATCCATGCGCTTTGCTTCGATCTCGACGCGCCCTCGCGGGTCCGGCTCGTCG
TGTCGAAGGGGGGCGCCCATGCGCTCGATGCCTCGGCCATGCCGGCGCCGATCGAAAGCCTGACCTGCGCGGTGCTCTCG
CTTCCGGTGTCGGACGGCGACTGGCGCCTGCGCCACAAGACCACGGACCGCGCCTTCTACGAGGCGGGCCTGTCCGCCGC
GAAACGGGCGGGCGCCGGTGAGGCCCTGTTCCTGCGCGACGATGGCTTCCTTACCGAAGGCACGTTCACCAACATCTTCG
TCGAGCGCGATGGCATTCTGCTCACCCCCCGCGCCGAACTCGGCCTGCTTCCCGGCGTACTGCGCCGAAGCCTGATCGAG
GCCGGACGTGCGGTCGAGGCGGACCTGACGCTCGATGACCTTGCCGGCGGCTTCCTCGTCGGCAACGCGCTGCGCGGCCT
CATCCCGGCTCGCCTGCTTGGCGCCTGA

Upstream 100 bases:

>100_bases
TGGCCCGAGACCAGTTGGCCCGAGACTAGGCCGCAGCCTTGTCCCTTGCGAGGGGTTTTTGCATCCGGAGCGGGTAACGG
CTAGAGCGCGCAGGAACGCC

Downstream 100 bases:

>100_bases
CATCATGAACCAGCTCTCCCGGGCGCTTGCGCGCATCGCTCCTTCCCGTACCACCGCTATCACCGACCGCGCGATCCAGC
TTCGCGCCGAAGGCCGCGAC

Product: para-aminobenzoate synthase, component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 595; Mature: 594

Protein sequence:

>595_residues
MTRAPFILLDDARSEGASDARLYEDAVEIVVARRAEEVEAALERIAAVPGNWAGYLAYEAGLALEPRLLPLAAVRTGADG
PLVWFARFDRVTRMPSAEVEQWLVRNARGPGRLGPLGPALSSGGYARAFDLVQEAIRAGDIYQANLTFPLTGTWDGDPLS
IYGEVRRDARAGYGGVIWDGAHWHLSFSPELFFKLSGGEARVRPMKGTAPRGATPEEDARFKADLSASVKDRAENLMIVD
LMRNDLARVSQAGSVKVEAPFAIESYPTVHQMVTTVRARLAPGEDVRSLLRAIFPCGSITGAPKIRAMEIIHAAERDARG
LYCGSIGRIDPTGEAAFNVAIRTLRLSSDHAGASGGRAVMGVGSAVVADSAMIGEWRECVVKGNFLRLSAGHADLIETMA
FDPAKGIELLELHLERMKASALALGYSFDRHAVRNAIHALCFDLDAPSRVRLVVSKGGAHALDASAMPAPIESLTCAVLS
LPVSDGDWRLRHKTTDRAFYEAGLSAAKRAGAGEALFLRDDGFLTEGTFTNIFVERDGILLTPRAELGLLPGVLRRSLIE
AGRAVEADLTLDDLAGGFLVGNALRGLIPARLLGA

Sequences:

>Translated_595_residues
MTRAPFILLDDARSEGASDARLYEDAVEIVVARRAEEVEAALERIAAVPGNWAGYLAYEAGLALEPRLLPLAAVRTGADG
PLVWFARFDRVTRMPSAEVEQWLVRNARGPGRLGPLGPALSSGGYARAFDLVQEAIRAGDIYQANLTFPLTGTWDGDPLS
IYGEVRRDARAGYGGVIWDGAHWHLSFSPELFFKLSGGEARVRPMKGTAPRGATPEEDARFKADLSASVKDRAENLMIVD
LMRNDLARVSQAGSVKVEAPFAIESYPTVHQMVTTVRARLAPGEDVRSLLRAIFPCGSITGAPKIRAMEIIHAAERDARG
LYCGSIGRIDPTGEAAFNVAIRTLRLSSDHAGASGGRAVMGVGSAVVADSAMIGEWRECVVKGNFLRLSAGHADLIETMA
FDPAKGIELLELHLERMKASALALGYSFDRHAVRNAIHALCFDLDAPSRVRLVVSKGGAHALDASAMPAPIESLTCAVLS
LPVSDGDWRLRHKTTDRAFYEAGLSAAKRAGAGEALFLRDDGFLTEGTFTNIFVERDGILLTPRAELGLLPGVLRRSLIE
AGRAVEADLTLDDLAGGFLVGNALRGLIPARLLGA
>Mature_594_residues
TRAPFILLDDARSEGASDARLYEDAVEIVVARRAEEVEAALERIAAVPGNWAGYLAYEAGLALEPRLLPLAAVRTGADGP
LVWFARFDRVTRMPSAEVEQWLVRNARGPGRLGPLGPALSSGGYARAFDLVQEAIRAGDIYQANLTFPLTGTWDGDPLSI
YGEVRRDARAGYGGVIWDGAHWHLSFSPELFFKLSGGEARVRPMKGTAPRGATPEEDARFKADLSASVKDRAENLMIVDL
MRNDLARVSQAGSVKVEAPFAIESYPTVHQMVTTVRARLAPGEDVRSLLRAIFPCGSITGAPKIRAMEIIHAAERDARGL
YCGSIGRIDPTGEAAFNVAIRTLRLSSDHAGASGGRAVMGVGSAVVADSAMIGEWRECVVKGNFLRLSAGHADLIETMAF
DPAKGIELLELHLERMKASALALGYSFDRHAVRNAIHALCFDLDAPSRVRLVVSKGGAHALDASAMPAPIESLTCAVLSL
PVSDGDWRLRHKTTDRAFYEAGLSAAKRAGAGEALFLRDDGFLTEGTFTNIFVERDGILLTPRAELGLLPGVLRRSLIEA
GRAVEADLTLDDLAGGFLVGNALRGLIPARLLGA

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=265, Percent_Identity=41.8867924528302, Blast_Score=198, Evalue=1e-51,
Organism=Escherichia coli, GI1787518, Length=268, Percent_Identity=30.9701492537313, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1786809, Length=195, Percent_Identity=26.1538461538462, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320935, Length=277, Percent_Identity=32.129963898917, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324361, Length=286, Percent_Identity=26.9230769230769, Blast_Score=87, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 63752; Mature: 63620

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAPFILLDDARSEGASDARLYEDAVEIVVARRAEEVEAALERIAAVPGNWAGYLAYEA
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
GLALEPRLLPLAAVRTGADGPLVWFARFDRVTRMPSAEVEQWLVRNARGPGRLGPLGPAL
CCCCCCCCCCHHHHHCCCCCCEEEEEHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCC
SSGGYARAFDLVQEAIRAGDIYQANLTFPLTGTWDGDPLSIYGEVRRDARAGYGGVIWDG
CCCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCEEHHHHHHHHHCCCCCCEEECC
AHWHLSFSPELFFKLSGGEARVRPMKGTAPRGATPEEDARFKADLSASVKDRAENLMIVD
EEEEEEECCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCEECCCCHHHHHHCCCEEEEH
LMRNDLARVSQAGSVKVEAPFAIESYPTVHQMVTTVRARLAPGEDVRSLLRAIFPCGSIT
HHHHHHHHHHCCCCEEEECCEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
GAPKIRAMEIIHAAERDARGLYCGSIGRIDPTGEAAFNVAIRTLRLSSDHAGASGGRAVM
CCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHEEEEEEEEECCCCCCCCCCEEEE
GVGSAVVADSAMIGEWRECVVKGNFLRLSAGHADLIETMAFDPAKGIELLELHLERMKAS
ECCCHHHHCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ALALGYSFDRHAVRNAIHALCFDLDAPSRVRLVVSKGGAHALDASAMPAPIESLTCAVLS
HHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEECCCCCCCCHHHHEEEEEE
LPVSDGDWRLRHKTTDRAFYEAGLSAAKRAGAGEALFLRDDGFLTEGTFTNIFVERDGIL
EECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCCEEEEEEECCCEE
LTPRAELGLLPGVLRRSLIEAGRAVEADLTLDDLAGGFLVGNALRGLIPARLLGA
ECCCHHHCCCHHHHHHHHHHCCCCEEECCCHHHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRAPFILLDDARSEGASDARLYEDAVEIVVARRAEEVEAALERIAAVPGNWAGYLAYEA
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
GLALEPRLLPLAAVRTGADGPLVWFARFDRVTRMPSAEVEQWLVRNARGPGRLGPLGPAL
CCCCCCCCCCHHHHHCCCCCCEEEEEHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCC
SSGGYARAFDLVQEAIRAGDIYQANLTFPLTGTWDGDPLSIYGEVRRDARAGYGGVIWDG
CCCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCEEHHHHHHHHHCCCCCCEEECC
AHWHLSFSPELFFKLSGGEARVRPMKGTAPRGATPEEDARFKADLSASVKDRAENLMIVD
EEEEEEECCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCEECCCCHHHHHHCCCEEEEH
LMRNDLARVSQAGSVKVEAPFAIESYPTVHQMVTTVRARLAPGEDVRSLLRAIFPCGSIT
HHHHHHHHHHCCCCEEEECCEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
GAPKIRAMEIIHAAERDARGLYCGSIGRIDPTGEAAFNVAIRTLRLSSDHAGASGGRAVM
CCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHEEEEEEEEECCCCCCCCCCEEEE
GVGSAVVADSAMIGEWRECVVKGNFLRLSAGHADLIETMAFDPAKGIELLELHLERMKAS
ECCCHHHHCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ALALGYSFDRHAVRNAIHALCFDLDAPSRVRLVVSKGGAHALDASAMPAPIESLTCAVLS
HHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEECCCCCCCCHHHHEEEEEE
LPVSDGDWRLRHKTTDRAFYEAGLSAAKRAGAGEALFLRDDGFLTEGTFTNIFVERDGIL
EECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCCEEEEEEECCCEE
LTPRAELGLLPGVLRRSLIEAGRAVEADLTLDDLAGGFLVGNALRGLIPARLLGA
ECCCHHHCCCHHHHHHHHHHCCCCEEECCCHHHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]