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The map label for this gene is htpX [H]

Identifier: 86751733

GI number: 86751733

Start: 5238884

End: 5239834

Strand: Reverse

Name: htpX [H]

Synonym: RPB_4635

Alternate gene names: 86751733

Gene position: 5239834-5238884 (Counterclockwise)

Preceding gene: 86751735

Following gene: 86751732

Centisome position: 98.28

GC content: 68.14

Gene sequence:

>951_bases
ATGAGTTACTTCAAAACCGCGATGTTGCTCGCCGGTATGACCGCGCTGTTCATGGGCGTCGGCTACCTGATCGGCGGCGC
CAGCGGCGCGATGATCGCGCTGGTCGTCGCTGCGGCGATGAACATCTTCACCTACTGGAATTCCGACCGGATGGTGCTGT
CGATGTACGGCGCGCAGCAGGTCGACGAACGCTCCGCGCCGGACCTGGTGCGGATGGTCGCCGAGCTGGCGGGTCGCGCC
GGCCTGCCGATGCCGCGCGTGTTCATCATGGACAACCCGCAGCCGAACGCGTTCGCGACCGGCCGCAATCCGGAGAACGC
CGCGGTCGCCGTCACCACCGGCCTGATGCAGTCGCTCAGCCGCGAGGAACTCGCCGGCGTGGTGGCGCACGAGCTCGCGC
ACATCAAGAACCACGACACGCTGCTGATGACCATCACCGCGACGATCGCCGGTGCGATCTCGATGGTGGCGCAGTTCGGC
ATGTTCTTCGGCGGCAACCGCGAGAACAACAACGGCCCGGGCCTGATCGGCTCGATTGCACTGATGATCCTGGCACCGCT
GGGCGCCATGTTGGTGCAGATGGCGATCAGCCGGACCCGTGAATACGCCGCGGACGAAATGGGCGCGCGGATCTGCGGCC
AGCCGATGTGGCTCGCTTCCGCGCTCGGCCGGATTGAAAACGCTGCGCATCAGGTGCCGAACTACGAGGCCGAGCGGGCG
CCGGCGACCGCGCATATGTTCATCATCAACCCGCTGTCGGGTCAGGGCATGGACAATCTGTTCTCGACCCATCCAGCGAC
CGCAAACCGGGTCGCTGCATTGCAGCGGCTGGCCGGTGAGATCGGCGGCGGTGGCGCGAGCTTCGGCCGGCCGACCCCGT
CACCGCGCGGGCCGTGGAGCGGTGCGCCGCGCGGCAGCGGCGAGCCCCGCGCGCGCGGCCCGTGGGGTTGA

Upstream 100 bases:

>100_bases
CGACGCGCTGCCGCACAAGACGATCTTGTTCGAAACCAAAGAGTTACCATCTCACGGATGCGTGACCTGCTCTACCGGAG
CGGGACGCAGGAGGAGGACC

Downstream 100 bases:

>100_bases
TGCGCCGGCACCGACCGCATTGCAGCATGAGAGAGCGAAGGCCCCAGATCACACCGGGGCCTTTTTGCTGACCATTGTTC
GCCCCCCTTATTGCGAGAGC

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSYFKTAMLLAGMTALFMGVGYLIGGASGAMIALVVAAAMNIFTYWNSDRMVLSMYGAQQVDERSAPDLVRMVAELAGRA
GLPMPRVFIMDNPQPNAFATGRNPENAAVAVTTGLMQSLSREELAGVVAHELAHIKNHDTLLMTITATIAGAISMVAQFG
MFFGGNRENNNGPGLIGSIALMILAPLGAMLVQMAISRTREYAADEMGARICGQPMWLASALGRIENAAHQVPNYEAERA
PATAHMFIINPLSGQGMDNLFSTHPATANRVAALQRLAGEIGGGGASFGRPTPSPRGPWSGAPRGSGEPRARGPWG

Sequences:

>Translated_316_residues
MSYFKTAMLLAGMTALFMGVGYLIGGASGAMIALVVAAAMNIFTYWNSDRMVLSMYGAQQVDERSAPDLVRMVAELAGRA
GLPMPRVFIMDNPQPNAFATGRNPENAAVAVTTGLMQSLSREELAGVVAHELAHIKNHDTLLMTITATIAGAISMVAQFG
MFFGGNRENNNGPGLIGSIALMILAPLGAMLVQMAISRTREYAADEMGARICGQPMWLASALGRIENAAHQVPNYEAERA
PATAHMFIINPLSGQGMDNLFSTHPATANRVAALQRLAGEIGGGGASFGRPTPSPRGPWSGAPRGSGEPRARGPWG
>Mature_315_residues
SYFKTAMLLAGMTALFMGVGYLIGGASGAMIALVVAAAMNIFTYWNSDRMVLSMYGAQQVDERSAPDLVRMVAELAGRAG
LPMPRVFIMDNPQPNAFATGRNPENAAVAVTTGLMQSLSREELAGVVAHELAHIKNHDTLLMTITATIAGAISMVAQFGM
FFGGNRENNNGPGLIGSIALMILAPLGAMLVQMAISRTREYAADEMGARICGQPMWLASALGRIENAAHQVPNYEAERAP
ATAHMFIINPLSGQGMDNLFSTHPATANRVAALQRLAGEIGGGGASFGRPTPSPRGPWSGAPRGSGEPRARGPWG

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=219, Percent_Identity=34.703196347032, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 33259; Mature: 33128

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYFKTAMLLAGMTALFMGVGYLIGGASGAMIALVVAAAMNIFTYWNSDRMVLSMYGAQQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCEEEEECCCHH
VDERSAPDLVRMVAELAGRAGLPMPRVFIMDNPQPNAFATGRNPENAAVAVTTGLMQSLS
HHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEECCCCCCCCEEHHHHHHHHHHH
REELAGVVAHELAHIKNHDTLLMTITATIAGAISMVAQFGMFFGGNRENNNGPGLIGSIA
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
LMILAPLGAMLVQMAISRTREYAADEMGARICGQPMWLASALGRIENAAHQVPNYEAERA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
PATAHMFIINPLSGQGMDNLFSTHPATANRVAALQRLAGEIGGGGASFGRPTPSPRGPWS
CCEEEEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GAPRGSGEPRARGPWG
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SYFKTAMLLAGMTALFMGVGYLIGGASGAMIALVVAAAMNIFTYWNSDRMVLSMYGAQQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCEEEEECCCHH
VDERSAPDLVRMVAELAGRAGLPMPRVFIMDNPQPNAFATGRNPENAAVAVTTGLMQSLS
HHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEECCCCCCCCEEHHHHHHHHHHH
REELAGVVAHELAHIKNHDTLLMTITATIAGAISMVAQFGMFFGGNRENNNGPGLIGSIA
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
LMILAPLGAMLVQMAISRTREYAADEMGARICGQPMWLASALGRIENAAHQVPNYEAERA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
PATAHMFIINPLSGQGMDNLFSTHPATANRVAALQRLAGEIGGGGASFGRPTPSPRGPWS
CCEEEEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GAPRGSGEPRARGPWG
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA