BacMap

Definition	Rhodopseudomonas palustris HaA2, complete genome.
Accession	NC_007778
Length	5,331,656

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The map label for this gene is fabG [H]

Identifier: 86751625

GI number: 86751625

Start: 5116506

End: 5117240

Strand: Reverse

Name: fabG [H]

Synonym: RPB_4527

Alternate gene names: 86751625

Gene position: 5117240-5116506 (Counterclockwise)

Preceding gene: 86751627

Following gene: 86751621

Centisome position: 95.98

GC content: 66.8

Gene sequence:

>735_bases
ATGAACGATCTCGATTTTGGCGGCCAGCAGATGCTGATCGTCGGCGGCTCGAGCGGCATCGGCAACGGCATCGCGCAGGC
GTTTCGCACGCGCGGCGCGAAAGTCTGCGTCACCGGCACCCGGGCGCAAACGTCCGACTACGCACCCGAAGACGGTAGCG
ATTTCGGCGGGCTGACTTACGCGCAGCTCGACGTCAGCAAGCCACAGGCGATCGAGGCGTTCGCGCCGGCGCTGGAGCGG
CTCGACGTGCTGGTGCTGGCGCAGGGCGCGGTGATCTATCGTCGCGGCGAGTTCGCGATGGACGGCTTCCGCCACGTGAT
GGAGGTCAATCTGATCAGCCTGATGGCCTGCGCGGTGAAGTTTCATCCGCTGCTCAAGGCGTCGTCCGGCAAGCTGATCA
TCGTCTCATCCACCGCGGCGTTTCACGCCACCAAGGGCAACCCGGCCTACAACGCCTCGAAGACCGGCGCGATGGGGCTG
ACCCGGACGCTGGCGCAGGCCTGGGCCGAGGACGGCATCCGCGTCAACGGCATCGCGCCCGGCCTGGTCGATACCAAAAT
GACCAAGGTCACCACCGCCAATCCGAAGCGGCTCGCCGGCGCCATCGAGGGCATTCCGATGCGGCGGCTCGGCACGCCGC
AGGAGATGGCCGGCGCGGCGTTGTTTCTCGCCTCGCCGTTGTCGTCCTACGTGCTCGGCCAGACCCTGGTGGTCGATGGC
GGGCTGATTTTGTAG

Upstream 100 bases:

>100_bases
CGTCGCGGTCCGGCTCCGATTGACAAGGCTCGCATCGATTGGGACACAGGTCAAACGCGCGCCGTCAGAGCCGCGACACG
ACAACAAGGGAGAAACCGCG

Downstream 100 bases:

>100_bases
CTGCGCGAACGCCCGAAACGATCAGCGGAAGATCGAGAAGAATCCCGACGCGGGCGGCGGCGGCGGGGGCGCGCGGCGCA
TCTGCGGCTGGGGCTGCGCC

Product: 3-oxoacyl-acyl carrier protein reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MNDLDFGGQQMLIVGGSSGIGNGIAQAFRTRGAKVCVTGTRAQTSDYAPEDGSDFGGLTYAQLDVSKPQAIEAFAPALER
LDVLVLAQGAVIYRRGEFAMDGFRHVMEVNLISLMACAVKFHPLLKASSGKLIIVSSTAAFHATKGNPAYNASKTGAMGL
TRTLAQAWAEDGIRVNGIAPGLVDTKMTKVTTANPKRLAGAIEGIPMRRLGTPQEMAGAALFLASPLSSYVLGQTLVVDG
GLIL

Sequences:

>Translated_244_residues
MNDLDFGGQQMLIVGGSSGIGNGIAQAFRTRGAKVCVTGTRAQTSDYAPEDGSDFGGLTYAQLDVSKPQAIEAFAPALER
LDVLVLAQGAVIYRRGEFAMDGFRHVMEVNLISLMACAVKFHPLLKASSGKLIIVSSTAAFHATKGNPAYNASKTGAMGL
TRTLAQAWAEDGIRVNGIAPGLVDTKMTKVTTANPKRLAGAIEGIPMRRLGTPQEMAGAALFLASPLSSYVLGQTLVVDG
GLIL
>Mature_244_residues
MNDLDFGGQQMLIVGGSSGIGNGIAQAFRTRGAKVCVTGTRAQTSDYAPEDGSDFGGLTYAQLDVSKPQAIEAFAPALER
LDVLVLAQGAVIYRRGEFAMDGFRHVMEVNLISLMACAVKFHPLLKASSGKLIIVSSTAAFHATKGNPAYNASKTGAMGL
TRTLAQAWAEDGIRVNGIAPGLVDTKMTKVTTANPKRLAGAIEGIPMRRLGTPQEMAGAALFLASPLSSYVLGQTLVVDG
GLIL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=240, Percent_Identity=34.1666666666667, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=32.7800829875519, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI5031737, Length=239, Percent_Identity=31.3807531380753, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=25.1968503937008, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI126723750, Length=242, Percent_Identity=29.7520661157025, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI66933014, Length=234, Percent_Identity=29.9145299145299, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=28.9795918367347, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=29.7619047619048, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=27.4590163934426, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=31.2169312169312, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI59889578, Length=168, Percent_Identity=32.7380952380952, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=32.5490196078431, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=33.739837398374, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=31.9838056680162, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=29.7619047619048, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=31.5384615384615, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=26.6409266409266, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=29.3877551020408, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI2367365, Length=245, Percent_Identity=29.3877551020408, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=27.9527559055118, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=28.8617886178862, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787545, Length=250, Percent_Identity=26, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=241, Percent_Identity=33.195020746888, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=30.4, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=30.6772908366534, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=31.0077519379845, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=31.3207547169811, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17560676, Length=240, Percent_Identity=28.75, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=31.0344827586207, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=32.0610687022901, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=28.957528957529, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=29.0076335877863, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=29.3893129770992, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=27.4809160305344, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=30.8880308880309, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=30.6513409961686, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=258, Percent_Identity=29.0697674418605, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=249, Percent_Identity=29.718875502008, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=27.4809160305344, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=29.6747967479675, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=28.7878787878788, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=27.2, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=259, Percent_Identity=25.8687258687259, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=260, Percent_Identity=24.2307692307692, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=25.3061224489796, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=264, Percent_Identity=25.3787878787879, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=26.9387755102041, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=25.8064516129032, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=28.4584980237154, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322861, Length=203, Percent_Identity=29.064039408867, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=30.9236947791165, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=30.241935483871, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644337, Length=251, Percent_Identity=34.6613545816733, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24643142, Length=239, Percent_Identity=29.2887029288703, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=29.3172690763052, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=29.3172690763052, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=29.4820717131474, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25472; Mature: 25472

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLDFGGQQMLIVGGSSGIGNGIAQAFRTRGAKVCVTGTRAQTSDYAPEDGSDFGGLTY
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEE
AQLDVSKPQAIEAFAPALERLDVLVLAQGAVIYRRGEFAMDGFRHVMEVNLISLMACAVK
EEEECCCCHHHHHHHHHHHHCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
FHPLLKASSGKLIIVSSTAAFHATKGNPAYNASKTGAMGLTRTLAQAWAEDGIRVNGIAP
HHHHEECCCCCEEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCC
GLVDTKMTKVTTANPKRLAGAIEGIPMRRLGTPQEMAGAALFLASPLSSYVLGQTLVVDG
CCCCCCEEEEECCCHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEECC
GLIL
CEEC
>Mature Secondary Structure
MNDLDFGGQQMLIVGGSSGIGNGIAQAFRTRGAKVCVTGTRAQTSDYAPEDGSDFGGLTY
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEE
AQLDVSKPQAIEAFAPALERLDVLVLAQGAVIYRRGEFAMDGFRHVMEVNLISLMACAVK
EEEECCCCHHHHHHHHHHHHCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
FHPLLKASSGKLIIVSSTAAFHATKGNPAYNASKTGAMGLTRTLAQAWAEDGIRVNGIAP
HHHHEECCCCCEEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCC
GLVDTKMTKVTTANPKRLAGAIEGIPMRRLGTPQEMAGAALFLASPLSSYVLGQTLVVDG
CCCCCCEEEEECCCHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEECC
GLIL
CEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]