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The map label for this gene is mmgC [H]

Identifier: 86751041

GI number: 86751041

Start: 4487123

End: 4488295

Strand: Reverse

Name: mmgC [H]

Synonym: RPB_3933

Alternate gene names: 86751041

Gene position: 4488295-4487123 (Counterclockwise)

Preceding gene: 86751047

Following gene: 86751038

Centisome position: 84.18

GC content: 65.81

Gene sequence:

>1173_bases
ATGATCCCCAACGCGCAGAGCATGTTCAATTTCGATCTCGGCGAGACCGCCGATGCGATCCGCGAGACGGTGCGGGATTT
CGCCTCGAACGAGATCGCGCCGCGCGCCGACGCGATCGACAAGACCAACACCTTCCCGCGCGATCTGTGGCCGAAGCTCG
GCGAGCTCGGGCTGCACGGCATCACCGTCGAGGAGGAGTATGGCGGGTCCGGTCTCGGTTATCTCGAGCACTGCATCGCG
GTCGAGGAAATCTCCCGCGCCTCCGCCTCGGTCGGCCTGTCCTACGGCGCGCATTCCAATCTCTGCATCAACCAGATCCG
CCGCAACGGCAGCGAGGCGCAGAAGCGCAAATATCTGCCGAAGCTGATCAGCGGCGAACATGTCGGCGCGCTGGCGATGT
CCGAGCCCGGCGCCGGCTCCGACGTGGTGTCGATGAAGACTCGCGCCGAGAAGAAGGGCGACCGCTTCGTCCTCAACGGC
AACAAGATGTGGATCACCAACGGCCCGATCGCCGAGACGCTGGTGGTCTACGCCAAGACCGATCCGAATGCCGGGCCGCG
CGGTATGACCGCGTTCCTGGTCGAGAAAGGCTTCAAGGGATTCAGCACCGCGCAGAAACTCGACAAGCTCGGCATGCGCG
GCTCCGACACCGGCGAACTGGTGTTCGAGGATTGCGAGGTGCCGGAGGAGAACGTGCTCGGCGAGGTCGGTCGCGGCGTC
AACGTGCTGATGAGCGGGCTGGACTACGAGCGCGCGGTGCTGGCGGCGGGGCCGCTCGGCATCATGCAGGCGTGCATGGA
CGTGGTGATGCCCTATGTGCACGAGCGCAAGCAGTTCGGGGAGCCGATCGGCACGTTCCAGCTGGTGCAGGCCAAGATCG
CCGACATGTATGTGACGATGAACGCCTCGCGCGCCTACGTCTATGCGGTGGCGAAGGCCTGCGACCGCGGCCAGACCACC
CGCGAGGACGCCGCCGGCGCCATCCTCTACGCTGCCGAGAAGGCGACGCAATGCGCGCTCGATGCGATCCAGCTGCTGGG
CGGCAACGGCTACATCAACGACTACCCGACCGGGCGCCTGTTGCGCGACGCCAAGCTCTACGAAATCGGCGCCGGCACCA
GCGAAATCCGCCGGATGCTGATCGGCCGCGAGCTGTTCGCCAAGACGGCGTAG

Upstream 100 bases:

>100_bases
GGAGCCTTCTCAGCCCTGCGGCGCCATGACATGGTGGCCGCAACCAGAACACTGGCGCGCGGCTTCAACGCTGCGCCCGA
CGAGTGGAGACGTTCCGACC

Downstream 100 bases:

>100_bases
GGCGGATAGTTCGGCGAAGAGCCTTCCCCGCGCAGGGCGTCATCTCTCCCCGCGCGCGGGGAGAGGTCGACCGGCGTAGC
GCAGCGAAGCCGGTCGGGTG

Product: Acyl-CoA dehydrogenase-like

Products: 3-methylbut-2-enoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MIPNAQSMFNFDLGETADAIRETVRDFASNEIAPRADAIDKTNTFPRDLWPKLGELGLHGITVEEEYGGSGLGYLEHCIA
VEEISRASASVGLSYGAHSNLCINQIRRNGSEAQKRKYLPKLISGEHVGALAMSEPGAGSDVVSMKTRAEKKGDRFVLNG
NKMWITNGPIAETLVVYAKTDPNAGPRGMTAFLVEKGFKGFSTAQKLDKLGMRGSDTGELVFEDCEVPEENVLGEVGRGV
NVLMSGLDYERAVLAAGPLGIMQACMDVVMPYVHERKQFGEPIGTFQLVQAKIADMYVTMNASRAYVYAVAKACDRGQTT
REDAAGAILYAAEKATQCALDAIQLLGGNGYINDYPTGRLLRDAKLYEIGAGTSEIRRMLIGRELFAKTA

Sequences:

>Translated_390_residues
MIPNAQSMFNFDLGETADAIRETVRDFASNEIAPRADAIDKTNTFPRDLWPKLGELGLHGITVEEEYGGSGLGYLEHCIA
VEEISRASASVGLSYGAHSNLCINQIRRNGSEAQKRKYLPKLISGEHVGALAMSEPGAGSDVVSMKTRAEKKGDRFVLNG
NKMWITNGPIAETLVVYAKTDPNAGPRGMTAFLVEKGFKGFSTAQKLDKLGMRGSDTGELVFEDCEVPEENVLGEVGRGV
NVLMSGLDYERAVLAAGPLGIMQACMDVVMPYVHERKQFGEPIGTFQLVQAKIADMYVTMNASRAYVYAVAKACDRGQTT
REDAAGAILYAAEKATQCALDAIQLLGGNGYINDYPTGRLLRDAKLYEIGAGTSEIRRMLIGRELFAKTA
>Mature_390_residues
MIPNAQSMFNFDLGETADAIRETVRDFASNEIAPRADAIDKTNTFPRDLWPKLGELGLHGITVEEEYGGSGLGYLEHCIA
VEEISRASASVGLSYGAHSNLCINQIRRNGSEAQKRKYLPKLISGEHVGALAMSEPGAGSDVVSMKTRAEKKGDRFVLNG
NKMWITNGPIAETLVVYAKTDPNAGPRGMTAFLVEKGFKGFSTAQKLDKLGMRGSDTGELVFEDCEVPEENVLGEVGRGV
NVLMSGLDYERAVLAAGPLGIMQACMDVVMPYVHERKQFGEPIGTFQLVQAKIADMYVTMNASRAYVYAVAKACDRGQTT
REDAAGAILYAAEKATQCALDAIQLLGGNGYINDYPTGRLLRDAKLYEIGAGTSEIRRMLIGRELFAKTA

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=379, Percent_Identity=65.4353562005277, Blast_Score=513, Evalue=1e-145,
Organism=Homo sapiens, GI226958414, Length=362, Percent_Identity=66.2983425414365, Blast_Score=492, Evalue=1e-139,
Organism=Homo sapiens, GI4557233, Length=377, Percent_Identity=41.3793103448276, Blast_Score=291, Evalue=6e-79,
Organism=Homo sapiens, GI4501859, Length=369, Percent_Identity=37.940379403794, Blast_Score=268, Evalue=6e-72,
Organism=Homo sapiens, GI187960098, Length=383, Percent_Identity=38.3812010443864, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI4557231, Length=383, Percent_Identity=38.3812010443864, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI4501857, Length=370, Percent_Identity=34.8648648648649, Blast_Score=238, Evalue=8e-63,
Organism=Homo sapiens, GI21361497, Length=372, Percent_Identity=38.4408602150538, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI76496475, Length=384, Percent_Identity=36.1979166666667, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI4557235, Length=384, Percent_Identity=36.1979166666667, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI7656849, Length=378, Percent_Identity=33.5978835978836, Blast_Score=222, Evalue=6e-58,
Organism=Homo sapiens, GI4503943, Length=371, Percent_Identity=31.5363881401617, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI7669494, Length=367, Percent_Identity=32.1525885558583, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI48976061, Length=284, Percent_Identity=28.169014084507, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI211971008, Length=284, Percent_Identity=28.169014084507, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI38505218, Length=320, Percent_Identity=23.75, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI218563752, Length=228, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI87081958, Length=380, Percent_Identity=31.3157894736842, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786223, Length=380, Percent_Identity=28.1578947368421, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI87082384, Length=258, Percent_Identity=27.906976744186, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87081702, Length=335, Percent_Identity=25.3731343283582, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=385, Percent_Identity=64.9350649350649, Blast_Score=518, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI17569725, Length=394, Percent_Identity=38.3248730964467, Blast_Score=265, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17534899, Length=385, Percent_Identity=37.6623376623377, Blast_Score=257, Evalue=6e-69,
Organism=Caenorhabditis elegans, GI17570075, Length=384, Percent_Identity=36.1979166666667, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17506239, Length=362, Percent_Identity=35.9116022099448, Blast_Score=245, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=35.8490566037736, Blast_Score=244, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI17533517, Length=371, Percent_Identity=34.5013477088949, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI71990804, Length=280, Percent_Identity=42.5, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI71985184, Length=351, Percent_Identity=34.7578347578348, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=36.1313868613139, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17534353, Length=375, Percent_Identity=29.3333333333333, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=38.695652173913, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI71985192, Length=285, Percent_Identity=35.0877192982456, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17551932, Length=369, Percent_Identity=30.8943089430894, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17505929, Length=384, Percent_Identity=30.7291666666667, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=30.9623430962343, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI86563381, Length=281, Percent_Identity=27.4021352313167, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI86563383, Length=281, Percent_Identity=27.4021352313167, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355753, Length=387, Percent_Identity=63.3074935400517, Blast_Score=494, Evalue=1e-140,
Organism=Drosophila melanogaster, GI21356377, Length=378, Percent_Identity=42.8571428571429, Blast_Score=312, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=40.3743315508021, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24660351, Length=387, Percent_Identity=39.5348837209302, Blast_Score=265, Evalue=6e-71,
Organism=Drosophila melanogaster, GI24666513, Length=364, Percent_Identity=36.2637362637363, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI281363737, Length=366, Percent_Identity=35.792349726776, Blast_Score=216, Evalue=1e-56,
Organism=Drosophila melanogaster, GI19920834, Length=388, Percent_Identity=30.6701030927835, Blast_Score=182, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.10

Molecular weight: Translated: 42211; Mature: 42211

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPNAQSMFNFDLGETADAIRETVRDFASNEIAPRADAIDKTNTFPRDLWPKLGELGLHG
CCCCCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
ITVEEEYGGSGLGYLEHCIAVEEISRASASVGLSYGAHSNLCINQIRRNGSEAQKRKYLP
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHH
KLISGEHVGALAMSEPGAGSDVVSMKTRAEKKGDRFVLNGNKMWITNGPIAETLVVYAKT
HHHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEECCCEEEEECCCCCEEEEEEEEC
DPNAGPRGMTAFLVEKGFKGFSTAQKLDKLGMRGSDTGELVFEDCEVPEENVLGEVGRGV
CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHCCCH
NVLMSGLDYERAVLAAGPLGIMQACMDVVMPYVHERKQFGEPIGTFQLVQAKIADMYVTM
HHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEE
NASRAYVYAVAKACDRGQTTREDAAGAILYAAEKATQCALDAIQLLGGNGYINDYPTGRL
CCCCHHHHHHHHHHHCCCCCHHHHCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LRDAKLYEIGAGTSEIRRMLIGRELFAKTA
HHCCCEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIPNAQSMFNFDLGETADAIRETVRDFASNEIAPRADAIDKTNTFPRDLWPKLGELGLHG
CCCCCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCC
ITVEEEYGGSGLGYLEHCIAVEEISRASASVGLSYGAHSNLCINQIRRNGSEAQKRKYLP
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHH
KLISGEHVGALAMSEPGAGSDVVSMKTRAEKKGDRFVLNGNKMWITNGPIAETLVVYAKT
HHHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEECCCEEEEECCCCCEEEEEEEEC
DPNAGPRGMTAFLVEKGFKGFSTAQKLDKLGMRGSDTGELVFEDCEVPEENVLGEVGRGV
CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHCCCH
NVLMSGLDYERAVLAAGPLGIMQACMDVVMPYVHERKQFGEPIGTFQLVQAKIADMYVTM
HHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEE
NASRAYVYAVAKACDRGQTTREDAAGAILYAAEKATQCALDAIQLLGGNGYINDYPTGRL
CCCCHHHHHHHHHHHCCCCCHHHHCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LRDAKLYEIGAGTSEIRRMLIGRELFAKTA
HHCCCEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-methylbutanoyl-CoA; acceptor

Specific reaction: 3-methylbutanoyl-CoA + acceptor = 3-methylbut-2-enoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]