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The map label for this gene is 86750868

Identifier: 86750868

GI number: 86750868

Start: 4294448

End: 4295200

Strand: Reverse

Name: 86750868

Synonym: RPB_3759

Alternate gene names: NA

Gene position: 4295200-4294448 (Counterclockwise)

Preceding gene: 86750871

Following gene: 86750866

Centisome position: 80.56

GC content: 59.5

Gene sequence:

>753_bases
TTGCCGTGGAATCGCTCTAGAAGACAGCCTCGCGATCCGTTCACCGCCTGGAAGATCATGCCCGCTTTGTCGAACAAGCC
CTACCGCATCGGCCGCTCCAAAACCGGGCTCGGCCTGTTCGCCACCCAGCCGATCAAGAAGGGCACCAAGATCATCCGTT
ATTTCGGGCCGATGCTCGACTGCAACAAGAAGAAGGACGACGCGGTCGAGAACAAATATCTGTTCCAGATCAGCAAGCGC
TGGACCGTCGACGGCTCGGTGCGCAAGAACATCGCGCGCTACATCAACCACGCCTGCAATCCGAACGCGGAGTCGGATGT
GAACGTGCGCAAGCGCAAGATCATCATCCGCGCGATCAAGAACATCGAGCCCGGCGACGAGATCAACTACGACTACGGCA
CCGATTACTTCAAAGAATATCTGAAGCCGATCGGCTGCAAATGCGAATCCTGCGAAAAGAAGCGCAAGAAGAAGGCCGCC
GAAGCCCGCGCCGAGAAGGCGAAGCTGAAAGAGAAGGCCGCGCGCAAGGCGCAGAAGCAGGCCGACAGGGACGCTGGCAA
GGCGAAGGCCGGCGGAAAGGCGAAGCCCGAGAAGGCCGTCAAGGCGAAGACGCCGAAGGGCAAATCTGCGAAGGCCAAGA
CTTCCAAGTCCGCGGCGTCCAAGTCCGATGCGTCCAAGTCCGCGGCGTCCAAGCCCAAGGCTTCGAAGACGTCGACGTCC
AAGATGTCGAAGTCCAAATCGAAAGCCGCCTAG

Upstream 100 bases:

>100_bases
CACATTCGAGGCCGTCGCGCGCGGCCGACGATGCCAGGCTGAACCGCAGATTTCGCCAGGCTGGGGAAGGTTCGTCGGGG
GGCCACGAAACCCCTGCCAA

Downstream 100 bases:

>100_bases
TTCGGTTCCCACCAAGGTCGTCATGCCGGGCTTGTCCCGAGCATCCACCAACGACGGCAGTTGCGGCGGGGAAGAACGTG
GATGGCCGGGACGAGCCCGG

Product: nuclear protein SET

Products: NA

Alternate protein names: Histone-Lysine N-Methyltransferase; HistoNe-Lysine N-Methyltransferase H3 Lysine-4 Specific

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MPWNRSRRQPRDPFTAWKIMPALSNKPYRIGRSKTGLGLFATQPIKKGTKIIRYFGPMLDCNKKKDDAVENKYLFQISKR
WTVDGSVRKNIARYINHACNPNAESDVNVRKRKIIIRAIKNIEPGDEINYDYGTDYFKEYLKPIGCKCESCEKKRKKKAA
EARAEKAKLKEKAARKAQKQADRDAGKAKAGGKAKPEKAVKAKTPKGKSAKAKTSKSAASKSDASKSAASKPKASKTSTS
KMSKSKSKAA

Sequences:

>Translated_250_residues
MPWNRSRRQPRDPFTAWKIMPALSNKPYRIGRSKTGLGLFATQPIKKGTKIIRYFGPMLDCNKKKDDAVENKYLFQISKR
WTVDGSVRKNIARYINHACNPNAESDVNVRKRKIIIRAIKNIEPGDEINYDYGTDYFKEYLKPIGCKCESCEKKRKKKAA
EARAEKAKLKEKAARKAQKQADRDAGKAKAGGKAKPEKAVKAKTPKGKSAKAKTSKSAASKSDASKSAASKPKASKTSTS
KMSKSKSKAA
>Mature_249_residues
PWNRSRRQPRDPFTAWKIMPALSNKPYRIGRSKTGLGLFATQPIKKGTKIIRYFGPMLDCNKKKDDAVENKYLFQISKRW
TVDGSVRKNIARYINHACNPNAESDVNVRKRKIIIRAIKNIEPGDEINYDYGTDYFKEYLKPIGCKCESCEKKRKKKAAE
ARAEKAKLKEKAARKAQKQADRDAGKAKAGGKAKPEKAVKAKTPKGKSAKAKTSKSAASKSDASKSAASKPKASKTSTSK
MSKSKSKAA

Specific function: Unknown

COG id: COG2940

COG function: function code R; Proteins containing SET domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91718902, Length=134, Percent_Identity=33.5820895522388, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI13699811, Length=160, Percent_Identity=29.375, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71993684, Length=218, Percent_Identity=29.8165137614679, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17565204, Length=136, Percent_Identity=36.7647058823529, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193210440, Length=131, Percent_Identity=32.824427480916, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321911, Length=134, Percent_Identity=29.1044776119403, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19550184, Length=126, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17136556, Length=126, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI62472551, Length=126, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17136558, Length=126, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19550181, Length=126, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24639197, Length=134, Percent_Identity=36.5671641791045, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28571451, Length=134, Percent_Identity=36.5671641791045, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281360813, Length=135, Percent_Identity=32.5925925925926, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641786, Length=135, Percent_Identity=32.5925925925926, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650756, Length=159, Percent_Identity=30.8176100628931, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737643, Length=187, Percent_Identity=27.807486631016, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 27830; Mature: 27699

Theoretical pI: Translated: 10.99; Mature: 10.99

Prosite motif: PS50280 SET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCC
>Mature Secondary Structure 
PWNRSRRQPRDPFTAWKIMPALSNKPYRIGRSKTGLGLFATQPIKKGTKIIRYFGPMLD
CCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCEEECCCHHHHHHHHHHHCCHHC
CNKKKDDAVENKYLFQISKRWTVDGSVRKNIARYINHACNPNAESDVNVRKRKIIIRAIK
CCCCCHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
NIEPGDEINYDYGTDYFKEYLKPIGCKCESCEKKRKKKAAEARAEKAKLKEKAARKAQKQ
CCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADRDAGKAKAGGKAKPEKAVKAKTPKGKSAKAKTSKSAASKSDASKSAASKPKASKTSTS
HHHHHCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KMSKSKSKAA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA