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The map label for this gene is cph1 [H]

Identifier: 86750138

GI number: 86750138

Start: 3443780

End: 3445312

Strand: Direct

Name: cph1 [H]

Synonym: RPB_3021

Alternate gene names: 86750138

Gene position: 3443780-3445312 (Clockwise)

Preceding gene: 86750137

Following gene: 86750139

Centisome position: 64.59

GC content: 63.67

Gene sequence:

>1533_bases
GTGACGCCGGAATCCACGCGGCGACGCGCTTTCATCCAGATCACGTTGCTGTCGCTGTCTTTTGCCGTGCTGGTTCTGAT
CAGCGTCGCCTCGGTGTTTCTGTTGCAGAAAGCCCGGGAGGACAGCGCCTGGGTCGCCCACACGCTCGAAGTCGAGAACC
AGATTTCCCTCGCCCAGCTGCAGATGCGCCGTGCCGAAAGCGCGGAGCGAGGCTTTCTGCTGACGAGTCAGCCTGAATTC
GTCGAAGAGTTCGAGAATTCCTCCGGCCAGGTGGTGCCGATGCTGCAACGCCTGCAGCAGCGGGTAGCCGACAATCCGGT
GCAGCGCGGGTTGGTCGACAAGAGCATCGTCATCGCACAGGCGAGGATCGAGCGGTTCAGGGAACTGATCGCGCTCGCGC
AGGCGGACCGCGCCGAGGAAGCTCGGCGCATCGTGCGCGCCGAAAGCGGCCGTGAGGCCATGAACCAGTTCGCCAACTTC
ATGGCGGCGATGCGGGCCGAAGAAAACAAGCTATTCGTGATGCGGACGGCGGCGGCCGATCGCAGCCAGTCTCTGGCGTC
GATCGTCACCACCACCGGCTCCGGCCTGGTGCTGGTGCTGGCCGGGCTCTCGATCTTCCTGGTGCGGCGCTCCGCGCGCG
CCCGTGACGACGCCGAAGCGCTGCTACGCGAGAACAATCTCAACCTCGAGAGCACCGTGTCCGAGCGCACCGCCGACCTG
CGCGAGGCCAACGAAGAGATCCAGCGCTTCGCCTATATCGTGAGCCACGATTTGCGCTCGCCGCTGGTGAACATCATGGG
ATTCACCAGCGAGCTCGAAGAACTGCGCAGCGACATCTTTCGCCGCATCGCCACGCTGAGCCGCGAAGTCGCCGACAAGC
AGATGCCGGAGAAGGCCGACAGCGACGGCGAGCCGGAGCTGCAGCCGGCCGACCAACAATTGTCGGAGGACTTCACCGAG
GCACTCGCCTTCATCAAATCGTCGATCGGCAAGATGGACCGGCTGATCAGCGCGATCCTCAACCTCACGCGCGAAGGCCG
CCGTCAGTTCCAGCCGGTTTCGATCGACACCCGGGAGCTGATCGAGAACATCGTCTCGACGGTGGCGCATCAGGCCGCCG
AGGCCAACGCCGAGATCCGCATCGAGCCGTTGCCGGAAATCGTCAGCGACCGCCTCGCGCTCGAACAGATCTTTTCGAAT
CTCATCGACAACGCTCTGAAATATCTCAGGAACGGTGTCCCCGGAGACATCCGGATCCGCGGTCGCCAGAAGCTCGGCTT
CGCGATCTTCGAGATCGCCGACAACGGACGGGGGATCGATCCCAAGGACCATCAGAGAATCTTTGATCTTTTCCGCCGTG
CCGGTACACAGGACAGGCCGGGTCAGGGGATCGGGCTCGCTCATGTTCGCGCGCTCGTGCGCCGCCTGGGTGGAACCATG
TCGGTGTCCTCGGCGCTCGGCGAGGGCTCGACCTTCACCATCACCTTGCCGATGAAATGGACCACGGCCACCAAACGGGA
ACCCCGCTCATGA

Upstream 100 bases:

>100_bases
GCGTGGAACCAAGTTCCGGCTCCCGCGTTAGCGTGGCTGCAGATTTGGCCGCCTTGCGGGGATTGTTCTTGCTTTGTTTC
AAATGGTCGGAGACCGCGCG

Downstream 100 bases:

>100_bases
GTAACCCAGTCACCATCATCATGATCGAGGACGACGAGGGCCACGCGCGCCTGATCGAGCGCAATATTCGCCGGTCCGGC
GTCAACAACGAGATCGTTCC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MTPESTRRRAFIQITLLSLSFAVLVLISVASVFLLQKAREDSAWVAHTLEVENQISLAQLQMRRAESAERGFLLTSQPEF
VEEFENSSGQVVPMLQRLQQRVADNPVQRGLVDKSIVIAQARIERFRELIALAQADRAEEARRIVRAESGREAMNQFANF
MAAMRAEENKLFVMRTAAADRSQSLASIVTTTGSGLVLVLAGLSIFLVRRSARARDDAEALLRENNLNLESTVSERTADL
REANEEIQRFAYIVSHDLRSPLVNIMGFTSELEELRSDIFRRIATLSREVADKQMPEKADSDGEPELQPADQQLSEDFTE
ALAFIKSSIGKMDRLISAILNLTREGRRQFQPVSIDTRELIENIVSTVAHQAAEANAEIRIEPLPEIVSDRLALEQIFSN
LIDNALKYLRNGVPGDIRIRGRQKLGFAIFEIADNGRGIDPKDHQRIFDLFRRAGTQDRPGQGIGLAHVRALVRRLGGTM
SVSSALGEGSTFTITLPMKWTTATKREPRS

Sequences:

>Translated_510_residues
MTPESTRRRAFIQITLLSLSFAVLVLISVASVFLLQKAREDSAWVAHTLEVENQISLAQLQMRRAESAERGFLLTSQPEF
VEEFENSSGQVVPMLQRLQQRVADNPVQRGLVDKSIVIAQARIERFRELIALAQADRAEEARRIVRAESGREAMNQFANF
MAAMRAEENKLFVMRTAAADRSQSLASIVTTTGSGLVLVLAGLSIFLVRRSARARDDAEALLRENNLNLESTVSERTADL
REANEEIQRFAYIVSHDLRSPLVNIMGFTSELEELRSDIFRRIATLSREVADKQMPEKADSDGEPELQPADQQLSEDFTE
ALAFIKSSIGKMDRLISAILNLTREGRRQFQPVSIDTRELIENIVSTVAHQAAEANAEIRIEPLPEIVSDRLALEQIFSN
LIDNALKYLRNGVPGDIRIRGRQKLGFAIFEIADNGRGIDPKDHQRIFDLFRRAGTQDRPGQGIGLAHVRALVRRLGGTM
SVSSALGEGSTFTITLPMKWTTATKREPRS
>Mature_509_residues
TPESTRRRAFIQITLLSLSFAVLVLISVASVFLLQKAREDSAWVAHTLEVENQISLAQLQMRRAESAERGFLLTSQPEFV
EEFENSSGQVVPMLQRLQQRVADNPVQRGLVDKSIVIAQARIERFRELIALAQADRAEEARRIVRAESGREAMNQFANFM
AAMRAEENKLFVMRTAAADRSQSLASIVTTTGSGLVLVLAGLSIFLVRRSARARDDAEALLRENNLNLESTVSERTADLR
EANEEIQRFAYIVSHDLRSPLVNIMGFTSELEELRSDIFRRIATLSREVADKQMPEKADSDGEPELQPADQQLSEDFTEA
LAFIKSSIGKMDRLISAILNLTREGRRQFQPVSIDTRELIENIVSTVAHQAAEANAEIRIEPLPEIVSDRLALEQIFSNL
IDNALKYLRNGVPGDIRIRGRQKLGFAIFEIADNGRGIDPKDHQRIFDLFRRAGTQDRPGQGIGLAHVRALVRRLGGTMS
VSSALGEGSTFTITLPMKWTTATKREPRS

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=270, Percent_Identity=28.1481481481481, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788713, Length=296, Percent_Identity=27.7027027027027, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790436, Length=317, Percent_Identity=26.1829652996845, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=297, Percent_Identity=24.2424242424242, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI145693157, Length=331, Percent_Identity=25.0755287009063, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786912, Length=285, Percent_Identity=27.719298245614, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788549, Length=250, Percent_Identity=27.2, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788393, Length=268, Percent_Identity=25, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57049; Mature: 56918

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPESTRRRAFIQITLLSLSFAVLVLISVASVFLLQKAREDSAWVAHTLEVENQISLAQL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHH
QMRRAESAERGFLLTSQPEFVEEFENSSGQVVPMLQRLQQRVADNPVQRGLVDKSIVIAQ
HHHHHHHHHCCEEECCCCHHHHHHHCCCCCEEHHHHHHHHHHCCCHHHHCCCHHHHHHHH
ARIERFRELIALAQADRAEEARRIVRAESGREAMNQFANFMAAMRAEENKLFVMRTAAAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
RSQSLASIVTTTGSGLVLVLAGLSIFLVRRSARARDDAEALLRENNLNLESTVSERTADL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHH
REANEEIQRFAYIVSHDLRSPLVNIMGFTSELEELRSDIFRRIATLSREVADKQMPEKAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SDGEPELQPADQQLSEDFTEALAFIKSSIGKMDRLISAILNLTREGRRQFQPVSIDTREL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
IENIVSTVAHQAAEANAEIRIEPLPEIVSDRLALEQIFSNLIDNALKYLRNGVPGDIRIR
HHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEC
GRQKLGFAIFEIADNGRGIDPKDHQRIFDLFRRAGTQDRPGQGIGLAHVRALVRRLGGTM
CCHHHCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCH
SVSSALGEGSTFTITLPMKWTTATKREPRS
HHHHHCCCCCEEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
TPESTRRRAFIQITLLSLSFAVLVLISVASVFLLQKAREDSAWVAHTLEVENQISLAQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHH
QMRRAESAERGFLLTSQPEFVEEFENSSGQVVPMLQRLQQRVADNPVQRGLVDKSIVIAQ
HHHHHHHHHCCEEECCCCHHHHHHHCCCCCEEHHHHHHHHHHCCCHHHHCCCHHHHHHHH
ARIERFRELIALAQADRAEEARRIVRAESGREAMNQFANFMAAMRAEENKLFVMRTAAAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
RSQSLASIVTTTGSGLVLVLAGLSIFLVRRSARARDDAEALLRENNLNLESTVSERTADL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHH
REANEEIQRFAYIVSHDLRSPLVNIMGFTSELEELRSDIFRRIATLSREVADKQMPEKAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SDGEPELQPADQQLSEDFTEALAFIKSSIGKMDRLISAILNLTREGRRQFQPVSIDTREL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
IENIVSTVAHQAAEANAEIRIEPLPEIVSDRLALEQIFSNLIDNALKYLRNGVPGDIRIR
HHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEC
GRQKLGFAIFEIADNGRGIDPKDHQRIFDLFRRAGTQDRPGQGIGLAHVRALVRRLGGTM
CCHHHCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCH
SVSSALGEGSTFTITLPMKWTTATKREPRS
HHHHHCCCCCEEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]