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The map label for this gene is aroQ

Identifier: 86750135

GI number: 86750135

Start: 3441189

End: 3441644

Strand: Direct

Name: aroQ

Synonym: RPB_3018

Alternate gene names: 86750135

Gene position: 3441189-3441644 (Clockwise)

Preceding gene: 86750133

Following gene: 86750136

Centisome position: 64.54

GC content: 64.47

Gene sequence:

>456_bases
ATGCCTCAAACGATTTACGTGCTCAATGGCCCGAACTTGAATCTGCTCGGGACCCGGGAGCCGGCGATTTACGGCCACGC
GACGCTGGCCGACGTCGAACGATTGTGCACCGAGACCGCTGCCAGTTGTGGTCTTTCAGCCGTTTGCCGGCAGTCCAACC
ACGAGGGCGAGTTGATCGACTGGATCCACCAGGCGCGCGACGAGCAGGCGGTGGGAATTGTGCTCAACGCCGGCGGCTAC
ACCCACACCTCGGTGGCGCTGCATGACGCGCTCGTCGGCGTGCAGATCCCGGCGGTGGAAGTCCACGTCTCCAACGTCTT
CGCCCGCGACAGCTTCCGCCATCATTCCTTCATCGCGAAGGCCGCCTTTGCCAGCCTGTGCGGCTTCGGCATCGACGGCT
ACCGGCTGGCCATCCTCGGCCTCGCCGCGAAAATCGGTACCAGCGCCAAGGCCTGA

Upstream 100 bases:

>100_bases
GACAATCAAGTGAATTTTGCCCGGACCGGTGCTGCAGCGCCGGATTTCGGCCCGACGGCGCGTCCGCCGGAGACCTTCGC
TGACATTGCCGGAAAGTCGG

Downstream 100 bases:

>100_bases
CCCGAGGCCGGACCCGCCCCACTCACTCAAGACATCTGGATCGAAACATGGCCCGCCAGCCTGACACCAAGACCGCCGCC
AAGCCGAAGGACGCCGCAAC

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MPQTIYVLNGPNLNLLGTREPAIYGHATLADVERLCTETAASCGLSAVCRQSNHEGELIDWIHQARDEQAVGIVLNAGGY
THTSVALHDALVGVQIPAVEVHVSNVFARDSFRHHSFIAKAAFASLCGFGIDGYRLAILGLAAKIGTSAKA

Sequences:

>Translated_151_residues
MPQTIYVLNGPNLNLLGTREPAIYGHATLADVERLCTETAASCGLSAVCRQSNHEGELIDWIHQARDEQAVGIVLNAGGY
THTSVALHDALVGVQIPAVEVHVSNVFARDSFRHHSFIAKAAFASLCGFGIDGYRLAILGLAAKIGTSAKA
>Mature_150_residues
PQTIYVLNGPNLNLLGTREPAIYGHATLADVERLCTETAASCGLSAVCRQSNHEGELIDWIHQARDEQAVGIVLNAGGYT
HTSVALHDALVGVQIPAVEVHVSNVFARDSFRHHSFIAKAAFASLCGFGIDGYRLAILGLAAKIGTSAKA

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_RHOP2 (Q2IVP0)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_486631.1
- ProteinModelPortal:   Q2IVP0
- SMR:   Q2IVP0
- STRING:   Q2IVP0
- GeneID:   3910817
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_3018
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   IMVINGP
- ProtClustDB:   PRK05395
- BioCyc:   RPAL316058:RPB_3018-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15993; Mature: 15862

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 24-24 ACT_SITE 102-102 BINDING 76-76 BINDING 82-82 BINDING 89-89 BINDING 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQTIYVLNGPNLNLLGTREPAIYGHATLADVERLCTETAASCGLSAVCRQSNHEGELID
CCCEEEEEECCCEEEEECCCCCEECCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHH
WIHQARDEQAVGIVLNAGGYTHTSVALHDALVGVQIPAVEVHVSNVFARDSFRHHSFIAK
HHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCEECCEEEEEECHHHHHCCCHHHHHHHH
AAFASLCGFGIDGYRLAILGLAAKIGTSAKA
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PQTIYVLNGPNLNLLGTREPAIYGHATLADVERLCTETAASCGLSAVCRQSNHEGELID
CCEEEEEECCCEEEEECCCCCEECCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHH
WIHQARDEQAVGIVLNAGGYTHTSVALHDALVGVQIPAVEVHVSNVFARDSFRHHSFIAK
HHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCEECCEEEEEECHHHHHCCCHHHHHHHH
AAFASLCGFGIDGYRLAILGLAAKIGTSAKA
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA