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The map label for this gene is cfa [H]

Identifier: 86750023

GI number: 86750023

Start: 3313121

End: 3314350

Strand: Direct

Name: cfa [H]

Synonym: RPB_2906

Alternate gene names: 86750023

Gene position: 3313121-3314350 (Clockwise)

Preceding gene: 86750022

Following gene: 86750024

Centisome position: 62.14

GC content: 64.55

Gene sequence:

>1230_bases
ATGTACGAGCTGGTGCTGCTGACCCCCGACAATGTTGACTCGAAGCTCGCCGGGATGCCGCGCGTGGTGCGAATGGCGCT
CGCCTTCGGTGCGCGGCTGCGCCGCGGCACGCTCGACGTCACCCTGCCCGATGGCCGCAGGTTCCGCATGGGCGGCGCCG
AGCCGGGCCCCGCCGCCGAAATGCGGCTGCACAATTACGCCTTCGCCTCGCGGCTGATCAACGGCGGCGACATCGGCATC
GCCGAAGCCTATCTCAACGGCGATTGGGACACGCCGGACCTGACCCAGTTCCTGTATCTGTTCTGCGTCAATCACGAGCT
GATCCAGGCGATGCTCGGCGACAATCCGATGATGCGCTTCGTCCAGGTGGTCCGGCACTGGTTCAACCGCAACACCAAGC
GGCAGGCGCGGCGCAACATCTACGCGCATTACGACATCGGCAACGCGTTCTATTCGGCCTGGCTCGATCCGAGCATGACC
TATTCCTCGGCGCTGTTCGAGGATCACACCCAGGACCTGACCGCGGCGCAGATCAACAAATATCAGCGGCTCGCCGAAGC
GATCGACCTGCGGCCGGGCCAGACCGTGCTGGAGATCGGCTGCGGCTGGGGCGGTTTCGCCGAATACGCCGCGAAGAATT
TCGACGCCCGCGTCGTCGGCCTCACCATCAGCAAGGAACAGCGCGACTTCGCCCAGGAGCGGATGCAGCGCGCCGGCCTC
GCCGACAAGGTCGAAATCCGGCTGCAGGACTATCGCGACGAACGCGGCCAATACGACCGCATCGCCTCGATCGAAATGAT
CGAGGCGGTCGGCGAGGAATTCTGGCCGCGCTATTTCTCACAATTGCGCGACCGGCTGATGCCCGGCGGGCTGGTCGGGA
TTCAGGCGATCACGATTCAGGACCGCTTCTTCCAGGCCTATCGCCGCGAGGTCGACTTCATCCAGCGCTACGTGTTCCCC
GGCGGGATGCTGCCCTCGCCCGGCGTGCTGAAATCGCTCGGCGACAGGTTCGGCGTCCCGGTCATTCGCGAGCGCATCTT
CGGAGAAGATTATGCCAAGACGCTCGCGACCTGGAGAGACAATTTCCGCGAGGCGTGGCCGACCCTGACGCCGCTCGGCT
TCGACGACCGCTTCCGGCGGCTGTGGGAGTACTATCTCGCTTATTGCGAGGCCGGATTCCTGTCCGGCAATATCGACGTC
CGGCAGGTGGTGTTCGCCAAGACCAACTGA

Upstream 100 bases:

>100_bases
GTCGAACGGCTTTGCAGCGCGGCCGCACGATGCTTATAGTAATCATACGTGAGCCCAGCGTTTCCATCTGTCCGACCTGG
GCGAGATCGATGGAAGTGAA

Downstream 100 bases:

>100_bases
GACCGCGCCCCCGCGACCGCATGCGCTGCACAATGAAGCAGCAGCGCTGCCTTGTGCCGTGCCGGCGCGTCACCTAGGTT
GTGGTCCCGCAACCGCATCC

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MYELVLLTPDNVDSKLAGMPRVVRMALAFGARLRRGTLDVTLPDGRRFRMGGAEPGPAAEMRLHNYAFASRLINGGDIGI
AEAYLNGDWDTPDLTQFLYLFCVNHELIQAMLGDNPMMRFVQVVRHWFNRNTKRQARRNIYAHYDIGNAFYSAWLDPSMT
YSSALFEDHTQDLTAAQINKYQRLAEAIDLRPGQTVLEIGCGWGGFAEYAAKNFDARVVGLTISKEQRDFAQERMQRAGL
ADKVEIRLQDYRDERGQYDRIASIEMIEAVGEEFWPRYFSQLRDRLMPGGLVGIQAITIQDRFFQAYRREVDFIQRYVFP
GGMLPSPGVLKSLGDRFGVPVIRERIFGEDYAKTLATWRDNFREAWPTLTPLGFDDRFRRLWEYYLAYCEAGFLSGNIDV
RQVVFAKTN

Sequences:

>Translated_409_residues
MYELVLLTPDNVDSKLAGMPRVVRMALAFGARLRRGTLDVTLPDGRRFRMGGAEPGPAAEMRLHNYAFASRLINGGDIGI
AEAYLNGDWDTPDLTQFLYLFCVNHELIQAMLGDNPMMRFVQVVRHWFNRNTKRQARRNIYAHYDIGNAFYSAWLDPSMT
YSSALFEDHTQDLTAAQINKYQRLAEAIDLRPGQTVLEIGCGWGGFAEYAAKNFDARVVGLTISKEQRDFAQERMQRAGL
ADKVEIRLQDYRDERGQYDRIASIEMIEAVGEEFWPRYFSQLRDRLMPGGLVGIQAITIQDRFFQAYRREVDFIQRYVFP
GGMLPSPGVLKSLGDRFGVPVIRERIFGEDYAKTLATWRDNFREAWPTLTPLGFDDRFRRLWEYYLAYCEAGFLSGNIDV
RQVVFAKTN
>Mature_409_residues
MYELVLLTPDNVDSKLAGMPRVVRMALAFGARLRRGTLDVTLPDGRRFRMGGAEPGPAAEMRLHNYAFASRLINGGDIGI
AEAYLNGDWDTPDLTQFLYLFCVNHELIQAMLGDNPMMRFVQVVRHWFNRNTKRQARRNIYAHYDIGNAFYSAWLDPSMT
YSSALFEDHTQDLTAAQINKYQRLAEAIDLRPGQTVLEIGCGWGGFAEYAAKNFDARVVGLTISKEQRDFAQERMQRAGL
ADKVEIRLQDYRDERGQYDRIASIEMIEAVGEEFWPRYFSQLRDRLMPGGLVGIQAITIQDRFFQAYRREVDFIQRYVFP
GGMLPSPGVLKSLGDRFGVPVIRERIFGEDYAKTLATWRDNFREAWPTLTPLGFDDRFRRLWEYYLAYCEAGFLSGNIDV
RQVVFAKTN

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=385, Percent_Identity=35.5844155844156, Blast_Score=209, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI133904226, Length=432, Percent_Identity=34.2592592592593, Blast_Score=241, Evalue=4e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 47054; Mature: 47054

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYELVLLTPDNVDSKLAGMPRVVRMALAFGARLRRGTLDVTLPDGRRFRMGGAEPGPAAE
CEEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCCCCHHH
MRLHNYAFASRLINGGDIGIAEAYLNGDWDTPDLTQFLYLFCVNHELIQAMLGDNPMMRF
HHHHHHHHHHHHCCCCCCEEEEHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VQVVRHWFNRNTKRQARRNIYAHYDIGNAFYSAWLDPSMTYSSALFEDHTQDLTAAQINK
HHHHHHHHCCCHHHHHHHCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
YQRLAEAIDLRPGQTVLEIGCGWGGFAEYAAKNFDARVVGLTISKEQRDFAQERMQRAGL
HHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHCCC
ADKVEIRLQDYRDERGQYDRIASIEMIEAVGEEFWPRYFSQLRDRLMPGGLVGIQAITIQ
CCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHH
DRFFQAYRREVDFIQRYVFPGGMLPSPGVLKSLGDRFGVPVIRERIFGEDYAKTLATWRD
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHH
NFREAWPTLTPLGFDDRFRRLWEYYLAYCEAGFLSGNIDVRQVVFAKTN
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MYELVLLTPDNVDSKLAGMPRVVRMALAFGARLRRGTLDVTLPDGRRFRMGGAEPGPAAE
CEEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCCCCHHH
MRLHNYAFASRLINGGDIGIAEAYLNGDWDTPDLTQFLYLFCVNHELIQAMLGDNPMMRF
HHHHHHHHHHHHCCCCCCEEEEHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VQVVRHWFNRNTKRQARRNIYAHYDIGNAFYSAWLDPSMTYSSALFEDHTQDLTAAQINK
HHHHHHHHCCCHHHHHHHCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
YQRLAEAIDLRPGQTVLEIGCGWGGFAEYAAKNFDARVVGLTISKEQRDFAQERMQRAGL
HHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHCCC
ADKVEIRLQDYRDERGQYDRIASIEMIEAVGEEFWPRYFSQLRDRLMPGGLVGIQAITIQ
CCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHH
DRFFQAYRREVDFIQRYVFPGGMLPSPGVLKSLGDRFGVPVIRERIFGEDYAKTLATWRD
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHH
NFREAWPTLTPLGFDDRFRRLWEYYLAYCEAGFLSGNIDVRQVVFAKTN
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]