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The map label for this gene is aidB [H]

Identifier: 86749547

GI number: 86749547

Start: 2784032

End: 2785681

Strand: Direct

Name: aidB [H]

Synonym: RPB_2427

Alternate gene names: 86749547

Gene position: 2784032-2785681 (Clockwise)

Preceding gene: 86749546

Following gene: 86749550

Centisome position: 52.22

GC content: 66.36

Gene sequence:

>1650_bases
ATGACGCAGCCGTCTTTCGCGACCCACGACGTCTTCAACCAGTCGCCGCCTTTCGAGGAGGTCGATCTGTTCGGGACCGA
TCGGCCGCTGGTCGAGGCGGTGACTTTCAACAATGGCGGTCATGCCCATGTCGAGCTCGAGGCGTTCGGGCGCAATTGGG
GCTCGGCGCATATGGCCGAGCGCGGCCGGCTCGCCAACGAGCAGACGCCGAAGCTCAAGACCTTCGACGCCAAGGGGCTG
CGCCGTGATCAGGTCGAGTTTCATCCCGCCTATCACGAACTGATGTCCGAGAGCTTCCACGCCGGCATCCACAATTCGAC
CTGGGACCACAACGGCCAGCCGGCCGGCGGCTCGGCCGAAGTGGTGCGGGCCGCGAAGTTCTACATGGCGGCGCAGGTGG
AGACCGGGCATCTGTGCCCGGTGACGATGACGCGCGCCTCCGTGGCTGCACTTGCCGCGCAGCCGGAGTTGCTTGCGCAG
ATCATGCCGGTTCTGAGCAGCAAGCGCTACGATCCCGCTTTCGCGCCGTGGTCCGAGAAGCGCGGCATGAGCGTCGGCAT
GGGCATGACCGAGAAGCAGGGCGGCACTGATGTGCGCAGCAACGCGACCCGCGCGATCCGCGACGGCGACGCCTATCGCA
TCATCGGCCACAAATGGTTCATGTCGGCGCCGATGTGCGACGCTTTTCTGGTGCTGGCGCAGGCGGAGGAAGGACTGAGC
TGTTTCTTCATGCCGCGCTTCAAGCCGGATGGTTCGATCAATGACATCCAGTTTCAGCGGCTGAAGGACAAGCTCGGCAA
TCGCTCCAACGCGTCGTCCGAAGTGGAATTCACCGGCGCTTATGCGGTGCCGGTCGGCGAGCCGGGGCGGGGCATCCGCA
CCATCATCCAGATGGTGCAGCTCACCCGGCAGGATTGCGCGATCGCCTCCGCAGGCTTGATGCGGTCCGGGCTCGCGCAC
GCGCTGCATCACGCCCGCCATCGCAGCGTGTTCCAGAAGCACCTCATCGACCACTCGCTGATGCAGTCGGTGCTCGCCGA
TATGGCGCTACAGGTCGAAGCCTCGGTGGCGCTGGTGATGCGGCTGTGCCGGGCGTTCGATCAGGCGCCGCACGATCATC
TCGAAGCCGCCTATATGCGGCTGATGACGCCGGCGGTGAAATACTGGGTGTGCAAATCGGCGCCGCCATTTCTCTACGAG
GCGATGGAGTGCATGGGCGGCAACGGCTATGTCGAGGACGGCATTCTGGCGCGTCACTATCGCGAGGCGCCGGTGAACGC
GATCTGGGAAGGCTCCGGCAATGTGATGTGCCTCGACGTGCTGCGCGCGATGTCACGCGAGAGCGACGCAGGCACCGAAG
TGCTGCAGAGCCTGATCCAGGACACTGCCGGCCTGACCGGCGGACCGGCCGCGGCGAGCCTGGTCGCCCGGGCATTCCTG
CAGGCCGACAACGAGCGCACCGCGCGGCTCGCGGTCGAGACGCTGGCGAAACTCGCCGCCGCCTCCGCGCTCAGCGAAAT
CCACCCCCCGCACGCCGAACTCTTCGCCCGGACGCGGCTGACGCCCGAGCCGGCGACGATGTACGGCGCGGCCGACCTGT
CGGCCGATCAGGCGCAAAGCTTGCTGGCGCGGGCGCTGCCGGAGATGTGA

Upstream 100 bases:

>100_bases
GTATTTCGACGGGGGGCCACAACCCGCGAACCGGCGTGATCTTGCGCGCGTTTGTGCTTAACATGCGCGCGAATCCATTT
GCCTCCCGCCGGGAACACTC

Downstream 100 bases:

>100_bases
TACCAGTCCCTGTCACCAAGTTCGTCATGCCCGCGCTTGTCGCGGGCATCCACGTTGTTCAGCGGTGCATCGTCCAAAGG
CGTGGATGGCCGGGACGAGC

Product: Acyl-CoA dehydrogenase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MTQPSFATHDVFNQSPPFEEVDLFGTDRPLVEAVTFNNGGHAHVELEAFGRNWGSAHMAERGRLANEQTPKLKTFDAKGL
RRDQVEFHPAYHELMSESFHAGIHNSTWDHNGQPAGGSAEVVRAAKFYMAAQVETGHLCPVTMTRASVAALAAQPELLAQ
IMPVLSSKRYDPAFAPWSEKRGMSVGMGMTEKQGGTDVRSNATRAIRDGDAYRIIGHKWFMSAPMCDAFLVLAQAEEGLS
CFFMPRFKPDGSINDIQFQRLKDKLGNRSNASSEVEFTGAYAVPVGEPGRGIRTIIQMVQLTRQDCAIASAGLMRSGLAH
ALHHARHRSVFQKHLIDHSLMQSVLADMALQVEASVALVMRLCRAFDQAPHDHLEAAYMRLMTPAVKYWVCKSAPPFLYE
AMECMGGNGYVEDGILARHYREAPVNAIWEGSGNVMCLDVLRAMSRESDAGTEVLQSLIQDTAGLTGGPAAASLVARAFL
QADNERTARLAVETLAKLAAASALSEIHPPHAELFARTRLTPEPATMYGAADLSADQAQSLLARALPEM

Sequences:

>Translated_549_residues
MTQPSFATHDVFNQSPPFEEVDLFGTDRPLVEAVTFNNGGHAHVELEAFGRNWGSAHMAERGRLANEQTPKLKTFDAKGL
RRDQVEFHPAYHELMSESFHAGIHNSTWDHNGQPAGGSAEVVRAAKFYMAAQVETGHLCPVTMTRASVAALAAQPELLAQ
IMPVLSSKRYDPAFAPWSEKRGMSVGMGMTEKQGGTDVRSNATRAIRDGDAYRIIGHKWFMSAPMCDAFLVLAQAEEGLS
CFFMPRFKPDGSINDIQFQRLKDKLGNRSNASSEVEFTGAYAVPVGEPGRGIRTIIQMVQLTRQDCAIASAGLMRSGLAH
ALHHARHRSVFQKHLIDHSLMQSVLADMALQVEASVALVMRLCRAFDQAPHDHLEAAYMRLMTPAVKYWVCKSAPPFLYE
AMECMGGNGYVEDGILARHYREAPVNAIWEGSGNVMCLDVLRAMSRESDAGTEVLQSLIQDTAGLTGGPAAASLVARAFL
QADNERTARLAVETLAKLAAASALSEIHPPHAELFARTRLTPEPATMYGAADLSADQAQSLLARALPEM
>Mature_548_residues
TQPSFATHDVFNQSPPFEEVDLFGTDRPLVEAVTFNNGGHAHVELEAFGRNWGSAHMAERGRLANEQTPKLKTFDAKGLR
RDQVEFHPAYHELMSESFHAGIHNSTWDHNGQPAGGSAEVVRAAKFYMAAQVETGHLCPVTMTRASVAALAAQPELLAQI
MPVLSSKRYDPAFAPWSEKRGMSVGMGMTEKQGGTDVRSNATRAIRDGDAYRIIGHKWFMSAPMCDAFLVLAQAEEGLSC
FFMPRFKPDGSINDIQFQRLKDKLGNRSNASSEVEFTGAYAVPVGEPGRGIRTIIQMVQLTRQDCAIASAGLMRSGLAHA
LHHARHRSVFQKHLIDHSLMQSVLADMALQVEASVALVMRLCRAFDQAPHDHLEAAYMRLMTPAVKYWVCKSAPPFLYEA
MECMGGNGYVEDGILARHYREAPVNAIWEGSGNVMCLDVLRAMSRESDAGTEVLQSLIQDTAGLTGGPAAASLVARAFLQ
ADNERTARLAVETLAKLAAASALSEIHPPHAELFARTRLTPEPATMYGAADLSADQAQSLLARALPEM

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=262, Percent_Identity=27.4809160305344, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI226958412, Length=271, Percent_Identity=25.830258302583, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI226958414, Length=271, Percent_Identity=25.830258302583, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI4501859, Length=272, Percent_Identity=26.4705882352941, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI4557235, Length=344, Percent_Identity=25.8720930232558, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI76496475, Length=344, Percent_Identity=25.8720930232558, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI7656849, Length=269, Percent_Identity=26.3940520446097, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI21361497, Length=309, Percent_Identity=25.5663430420712, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4557231, Length=267, Percent_Identity=24.3445692883895, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI187960098, Length=267, Percent_Identity=24.3445692883895, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI87082384, Length=452, Percent_Identity=50.2212389380531, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI87081958, Length=276, Percent_Identity=23.9130434782609, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI86563383, Length=469, Percent_Identity=31.1300639658849, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI86563381, Length=469, Percent_Identity=31.1300639658849, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17538396, Length=270, Percent_Identity=27.4074074074074, Blast_Score=99, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=256, Percent_Identity=25.78125, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17506239, Length=268, Percent_Identity=24.6268656716418, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17569725, Length=269, Percent_Identity=23.0483271375465, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17534899, Length=270, Percent_Identity=24.0740740740741, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71990804, Length=252, Percent_Identity=25.3968253968254, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17533517, Length=267, Percent_Identity=25.4681647940075, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21356377, Length=269, Percent_Identity=27.1375464684015, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646207, Length=269, Percent_Identity=27.1375464684015, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281363737, Length=301, Percent_Identity=24.2524916943522, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355753, Length=277, Percent_Identity=25.9927797833935, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24666513, Length=269, Percent_Identity=24.5353159851301, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24660351, Length=270, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 59930; Mature: 59799

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPSFATHDVFNQSPPFEEVDLFGTDRPLVEAVTFNNGGHAHVELEAFGRNWGSAHMAE
CCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCHHHHH
RGRLANEQTPKLKTFDAKGLRRDQVEFHPAYHELMSESFHAGIHNSTWDHNGQPAGGSAE
HCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
VVRAAKFYMAAQVETGHLCPVTMTRASVAALAAQPELLAQIMPVLSSKRYDPAFAPWSEK
HHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHC
RGMSVGMGMTEKQGGTDVRSNATRAIRDGDAYRIIGHKWFMSAPMCDAFLVLAQAEEGLS
CCCEECCCCCCCCCCCCHHHCCHHHHCCCCEEEEECHHHHHCCCHHHHHHHHHHHCCCCE
CFFMPRFKPDGSINDIQFQRLKDKLGNRSNASSEVEFTGAYAVPVGEPGRGIRTIIQMVQ
EEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHH
LTRQDCAIASAGLMRSGLAHALHHARHRSVFQKHLIDHSLMQSVLADMALQVEASVALVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLCRAFDQAPHDHLEAAYMRLMTPAVKYWVCKSAPPFLYEAMECMGGNGYVEDGILARHY
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHH
REAPVNAIWEGSGNVMCLDVLRAMSRESDAGTEVLQSLIQDTAGLTGGPAAASLVARAFL
HCCCCCEEEECCCCEEHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
QADNERTARLAVETLAKLAAASALSEIHPPHAELFARTRLTPEPATMYGAADLSADQAQS
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEECCCCCCHHHHHH
LLARALPEM
HHHHHCCCC
>Mature Secondary Structure 
TQPSFATHDVFNQSPPFEEVDLFGTDRPLVEAVTFNNGGHAHVELEAFGRNWGSAHMAE
CCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCHHHHH
RGRLANEQTPKLKTFDAKGLRRDQVEFHPAYHELMSESFHAGIHNSTWDHNGQPAGGSAE
HCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
VVRAAKFYMAAQVETGHLCPVTMTRASVAALAAQPELLAQIMPVLSSKRYDPAFAPWSEK
HHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHC
RGMSVGMGMTEKQGGTDVRSNATRAIRDGDAYRIIGHKWFMSAPMCDAFLVLAQAEEGLS
CCCEECCCCCCCCCCCCHHHCCHHHHCCCCEEEEECHHHHHCCCHHHHHHHHHHHCCCCE
CFFMPRFKPDGSINDIQFQRLKDKLGNRSNASSEVEFTGAYAVPVGEPGRGIRTIIQMVQ
EEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHH
LTRQDCAIASAGLMRSGLAHALHHARHRSVFQKHLIDHSLMQSVLADMALQVEASVALVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLCRAFDQAPHDHLEAAYMRLMTPAVKYWVCKSAPPFLYEAMECMGGNGYVEDGILARHY
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHH
REAPVNAIWEGSGNVMCLDVLRAMSRESDAGTEVLQSLIQDTAGLTGGPAAASLVARAFL
HCCCCCEEEECCCCEEHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
QADNERTARLAVETLAKLAAASALSEIHPPHAELFARTRLTPEPATMYGAADLSADQAQS
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEECCCCCCHHHHHH
LLARALPEM
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]