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The map label for this gene is nahR [H]

Identifier: 86749097

GI number: 86749097

Start: 2239951

End: 2240904

Strand: Reverse

Name: nahR [H]

Synonym: RPB_1974

Alternate gene names: 86749097

Gene position: 2240904-2239951 (Counterclockwise)

Preceding gene: 86749099

Following gene: 86749096

Centisome position: 42.03

GC content: 66.25

Gene sequence:

>954_bases
ATGGCGACGATCAATCTGCGTAATGTCGATCTCAATCTGCTGATCGTGTTCGACGCGGTGTATGCCACCGGCAATATCAG
CCACGCCGCGCGGCAGCTGGCGCTGAGCCAGCCGGCGGTCTCGAACGCGCTGACGCGGTTGCGCGAGCATTTCGACGATC
CGCTGTTCGTGCGCGCCGGCCGCGGCGTCAAGCCGACGCTGCGCTCGCAGCAGATGATCGAACCCGTGCGCGAAGCGCTG
CGGCTGATCCGCCAGCAATTCGACGGCGACCGCAGCCTCGACCTCGGCTCCTACAAGCGCACCTTCCGGATCGTCATCGT
CGATCCCCTGGAAGCCATGCTGATGCCGACGATGCTGCGCGAGATCAGCGCGCACGCGCCGCAGGTGACGATCGAATCCC
GGCCGCCATGGAACACCAATGTCGCCGACGCTATCATCGCCGGCACGCTGGATCTGGCCTGCTACACCTTTCCGGTCAGC
GCGCCGGGACTGGTGTTCAAGACCATCTGCCCGTGCGACCACGTCATCGTGGCGCGCCGCGGCCACCCGAAGATCGGCGC
CACGCTGGACGCCGAGACCTTCCTGTCACTGGCTCAGGTCGCGCTGATCCCGGAACTGCGCGGCCACACCAACATCGATC
GCGACATCACCACCCGCGGCGGCAACCGGCGGATCGCCTACATGGTCAACAAGGTGTGGTCGATGCCGGGCGTCGTCGGC
AGCACCGACCTGGTCACCGTGATGCCGCGCCGGTTCGCCGAACTGATGGCGCCGAAATTCGGTCTGCAGATCTTCGAGTC
GCCGATCCCGATCTCGCCGCAGGACTATCACATGATCTGGCACGAGAAGAACACCGACGACCCCGGCCACAAATGGCTGC
GCGACACCATGGTGAAGGCGATGCAGCCCGATCCCGCGCCGGCCGGGCTGGTCCCGGCCGCAGCCGCGTGCTAG

Upstream 100 bases:

>100_bases
TTCGTCATGGTGGGCGGGCCGCCGCTGATCTATCTATCAGCCGCGCGAATGATTGAAGCTTGCCTTGCAAGATCAAGGCG
ACAGGGGGACGGCGGGGCCG

Downstream 100 bases:

>100_bases
CCCTCCCCGCAACAACAGCGGGGAGACGAAACGCGATGGTCGAGGCGGTGATCTGGGATTTCGGCGGGGTGCTCACGACC
TCGCCGTTCGAGGCGTTCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MATINLRNVDLNLLIVFDAVYATGNISHAARQLALSQPAVSNALTRLREHFDDPLFVRAGRGVKPTLRSQQMIEPVREAL
RLIRQQFDGDRSLDLGSYKRTFRIVIVDPLEAMLMPTMLREISAHAPQVTIESRPPWNTNVADAIIAGTLDLACYTFPVS
APGLVFKTICPCDHVIVARRGHPKIGATLDAETFLSLAQVALIPELRGHTNIDRDITTRGGNRRIAYMVNKVWSMPGVVG
STDLVTVMPRRFAELMAPKFGLQIFESPIPISPQDYHMIWHEKNTDDPGHKWLRDTMVKAMQPDPAPAGLVPAAAAC

Sequences:

>Translated_317_residues
MATINLRNVDLNLLIVFDAVYATGNISHAARQLALSQPAVSNALTRLREHFDDPLFVRAGRGVKPTLRSQQMIEPVREAL
RLIRQQFDGDRSLDLGSYKRTFRIVIVDPLEAMLMPTMLREISAHAPQVTIESRPPWNTNVADAIIAGTLDLACYTFPVS
APGLVFKTICPCDHVIVARRGHPKIGATLDAETFLSLAQVALIPELRGHTNIDRDITTRGGNRRIAYMVNKVWSMPGVVG
STDLVTVMPRRFAELMAPKFGLQIFESPIPISPQDYHMIWHEKNTDDPGHKWLRDTMVKAMQPDPAPAGLVPAAAAC
>Mature_316_residues
ATINLRNVDLNLLIVFDAVYATGNISHAARQLALSQPAVSNALTRLREHFDDPLFVRAGRGVKPTLRSQQMIEPVREALR
LIRQQFDGDRSLDLGSYKRTFRIVIVDPLEAMLMPTMLREISAHAPQVTIESRPPWNTNVADAIIAGTLDLACYTFPVSA
PGLVFKTICPCDHVIVARRGHPKIGATLDAETFLSLAQVALIPELRGHTNIDRDITTRGGNRRIAYMVNKVWSMPGVVGS
TDLVTVMPRRFAELMAPKFGLQIFESPIPISPQDYHMIWHEKNTDDPGHKWLRDTMVKAMQPDPAPAGLVPAAAAC

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=295, Percent_Identity=31.5254237288136, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI87081766, Length=284, Percent_Identity=27.4647887323944, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786820, Length=281, Percent_Identity=25.9786476868327, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790147, Length=294, Percent_Identity=23.1292517006803, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35112; Mature: 34981

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATINLRNVDLNLLIVFDAVYATGNISHAARQLALSQPAVSNALTRLREHFDDPLFVRAG
CCEEEEECCCEEEEEEEEHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECC
RGVKPTLRSQQMIEPVREALRLIRQQFDGDRSLDLGSYKRTFRIVIVDPLEAMLMPTMLR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHH
EISAHAPQVTIESRPPWNTNVADAIIAGTLDLACYTFPVSAPGLVFKTICPCDHVIVARR
HHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHEEEEECCCCCCHHHHHHCCCCCEEEEEC
GHPKIGATLDAETFLSLAQVALIPELRGHTNIDRDITTRGGNRRIAYMVNKVWSMPGVVG
CCCCCCCEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCC
STDLVTVMPRRFAELMAPKFGLQIFESPIPISPQDYHMIWHEKNTDDPGHKWLRDTMVKA
CCHHHHHHHHHHHHHHCCHHCHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
MQPDPAPAGLVPAAAAC
CCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
ATINLRNVDLNLLIVFDAVYATGNISHAARQLALSQPAVSNALTRLREHFDDPLFVRAG
CEEEEECCCEEEEEEEEHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECC
RGVKPTLRSQQMIEPVREALRLIRQQFDGDRSLDLGSYKRTFRIVIVDPLEAMLMPTMLR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHH
EISAHAPQVTIESRPPWNTNVADAIIAGTLDLACYTFPVSAPGLVFKTICPCDHVIVARR
HHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHEEEEECCCCCCHHHHHHCCCCCEEEEEC
GHPKIGATLDAETFLSLAQVALIPELRGHTNIDRDITTRGGNRRIAYMVNKVWSMPGVVG
CCCCCCCEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCC
STDLVTVMPRRFAELMAPKFGLQIFESPIPISPQDYHMIWHEKNTDDPGHKWLRDTMVKA
CCHHHHHHHHHHHHHHCCHHCHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
MQPDPAPAGLVPAAAAC
CCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]