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The map label for this gene is ompR [H]

Identifier: 86749084

GI number: 86749084

Start: 2228709

End: 2229431

Strand: Reverse

Name: ompR [H]

Synonym: RPB_1961

Alternate gene names: 86749084

Gene position: 2229431-2228709 (Counterclockwise)

Preceding gene: 86749087

Following gene: 86749083

Centisome position: 41.81

GC content: 68.6

Gene sequence:

>723_bases
ATGAGCACCGCCCCGCCCCATATCCTCGTCGTCGAAGACGACCGGGAAACCCGCGCGCTGATCGCGAAATACCTTCGCAA
CAACGAATGTCATGTCGTGACCGCGCAGGACGGCCGCGAGATGGACAGCCGGCTCTCCGACCAGCGCGTCGACCTCGTCG
TGCTCGACGTGATGCTGCCGGGCGAGGACGGCCTCAGCCTGTGCCGGCGCGTGCGGGCGAGCTCGCCGCTGCCGATCATC
ATGCTGACGGCGCGCGGCGAGGACGTCGACCGTATCCTCGGCCTGGAGATGGGCGCCGACGACTACCTCGCCAAGCCGTT
CAATCCGCGCGAATTGCTGGCGCGGATCCGCTCGGTGCTGCGCCGCCAGTCGCTCGCCCAGACCGCCAGCGCCACGTCCG
GCGCGACCGCGCTCACCTTCCTCGGCTGGCGGATCGATTTCCGGCTGCGCGAACTGCGCAACCCCGATGGCGCCCTGGTG
GCGATGACCAGCGCCGAATTCGACCTGCTGCAGGCGTTCTGCGAACGGCCCGGCCGGGTGCTGTCGCGCGAAGCGCTGCT
CGATCTCACCCACGGCCGCAACGCCGGCTCGTTCGAGCGTTCGATCGACGTGCTGGTCAGCCGGATCCGCCGCAAGATCG
AGCCCGACCCGCAGAGCGTCAGCATCATCAAGACGGTGCGCTCCGGCGGCTATATGTTCACGCCCGCCGTCGAAACGGTT
TGA

Upstream 100 bases:

>100_bases
CCACACGGCCTGATTGCGGAATGTTGCAGCGTTTCCACGAGACATATCGGGAAACAAAAAACTCGTTTCAGCTTCGCGCG
GAATTTCGGTAAACGGCGTC

Downstream 100 bases:

>100_bases
TCGAGGCCGCTGCGGCCGGAGGCTTCATGCTCGAGCGGCTCGGCAGGTTTCGATTCAGCGGCATCCGCAGCCAGATCGCG
GTGCTGGTGTTGGCGTCGCT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSTAPPHILVVEDDRETRALIAKYLRNNECHVVTAQDGREMDSRLSDQRVDLVVLDVMLPGEDGLSLCRRVRASSPLPII
MLTARGEDVDRILGLEMGADDYLAKPFNPRELLARIRSVLRRQSLAQTASATSGATALTFLGWRIDFRLRELRNPDGALV
AMTSAEFDLLQAFCERPGRVLSREALLDLTHGRNAGSFERSIDVLVSRIRRKIEPDPQSVSIIKTVRSGGYMFTPAVETV

Sequences:

>Translated_240_residues
MSTAPPHILVVEDDRETRALIAKYLRNNECHVVTAQDGREMDSRLSDQRVDLVVLDVMLPGEDGLSLCRRVRASSPLPII
MLTARGEDVDRILGLEMGADDYLAKPFNPRELLARIRSVLRRQSLAQTASATSGATALTFLGWRIDFRLRELRNPDGALV
AMTSAEFDLLQAFCERPGRVLSREALLDLTHGRNAGSFERSIDVLVSRIRRKIEPDPQSVSIIKTVRSGGYMFTPAVETV
>Mature_239_residues
STAPPHILVVEDDRETRALIAKYLRNNECHVVTAQDGREMDSRLSDQRVDLVVLDVMLPGEDGLSLCRRVRASSPLPIIM
LTARGEDVDRILGLEMGADDYLAKPFNPRELLARIRSVLRRQSLAQTASATSGATALTFLGWRIDFRLRELRNPDGALVA
MTSAEFDLLQAFCERPGRVLSREALLDLTHGRNAGSFERSIDVLVSRIRRKIEPDPQSVSIIKTVRSGGYMFTPAVETV

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=48.0349344978166, Blast_Score=211, Evalue=3e-56,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=39.7435897435897, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=36.8421052631579, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=36.3247863247863, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=37.3390557939914, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=38.4279475982533, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=37.3949579831933, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=35.0649350649351, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=33.7719298245614, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=36.5638766519824, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=33.4801762114537, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=32.15859030837, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790552, Length=235, Percent_Identity=32.3404255319149, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=31.1111111111111, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790299, Length=122, Percent_Identity=30.327868852459, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788905, Length=133, Percent_Identity=33.0827067669173, Blast_Score=61, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=144, Percent_Identity=34.0277777777778, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26728; Mature: 26597

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAPPHILVVEDDRETRALIAKYLRNNECHVVTAQDGREMDSRLSDQRVDLVVLDVMLP
CCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCEEEEEEEEEC
GEDGLSLCRRVRASSPLPIIMLTARGEDVDRILGLEMGADDYLAKPFNPRELLARIRSVL
CCHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHH
RRQSLAQTASATSGATALTFLGWRIDFRLRELRNPDGALVAMTSAEFDLLQAFCERPGRV
HHHHHHHHHCCCCCCCEEEHHHHEEHHHHHHCCCCCCCEEEEECCHHHHHHHHHHCCCHH
LSREALLDLTHGRNAGSFERSIDVLVSRIRRKIEPDPQSVSIIKTVRSGGYMFTPAVETV
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure 
STAPPHILVVEDDRETRALIAKYLRNNECHVVTAQDGREMDSRLSDQRVDLVVLDVMLP
CCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCEEEEEEEEEC
GEDGLSLCRRVRASSPLPIIMLTARGEDVDRILGLEMGADDYLAKPFNPRELLARIRSVL
CCHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHH
RRQSLAQTASATSGATALTFLGWRIDFRLRELRNPDGALVAMTSAEFDLLQAFCERPGRV
HHHHHHHHHCCCCCCCEEEHHHHEEHHHHHHCCCCCCCEEEEECCHHHHHHHHHHCCCHH
LSREALLDLTHGRNAGSFERSIDVLVSRIRRKIEPDPQSVSIIKTVRSGGYMFTPAVETV
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]